Scientists uncover vulnerable enzyme that can be targeted to kill dangerous pathogens

Washington, August 28 (ANI): A collaborative study conducted by researchers from three institutions in the U.S. has shown that an enzyme, which is essential to many bacteria, can be targeted to kill dangerous pathogens.

Experts at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have also identified chemical compounds that can inhibit this enzyme, and suppress the growth of pathogenic bacteria.

Writing about their study in the journal Chemistry and Biology, the researchers say that their findings are essential to develop new broad-spectrum antibacterial agents to overcome multi-drug resistance.

Dr. Andrei Osterman, an associate professor in Burnham’s ioinformatics and Systems Biology program, targeted the acterial nicotinate mononucleotide adenylyltransferase (NadD), an essential enzyme for nicotinamide adenine dinculeotide (NAD) biosynthesis, which has many crucial functions in nearly all important pathogens.

The bacterial NadD differs significantly from the human enzyme.

“It’s clear that because of bacterial resistance, we need new, wide-spectrum antibiotics. This enzyme is indispensable in many pathogens, so finding ways to inhibit it could give us new options against infection,” said Dr. Osterman.

The research team used a structure-based approach to search for low-molecular-weight compounds that would selectively inhibit bacterial NadD, but not the human equivalent, by screening, in silico, more than a million compounds.

In their experiments, they tested the best predicted compounds against Escherichia coli and Bacillus anthracis (anthrax), which led them to a handful of versatile inhibitory chemotypes, which they explored in detail.

Using protein crystallography, a 3D structure of the enzyme in complex with one of the inhibitors was solved providing guidelines for further drug improvement.

“This is proof-of-concept that NadD is a good target to create antibacterial agents. This knowledge will be useful for both biodefense and public health. The next step is to find better inhibitors. We do not have a silver bullet yet, but we are certainly hitting a golden target,” said Dr Osterman.

The research was supported by a grant from the National Institute of Allergy and Infectious Diseases. (ANI)

‘Mobile ID’ devices herald next generation of biometric gadgets

Washington, August 27 (ANI): Reports indicate that a new generation of small, portable, versatile biometric devices, referred to as ‘Mobile ID’, are flourishing.

These devices gather, process and transmit an individual’s biometric data, which includes fingerprints, facial and iris images.

They were developed by NIST (National Institute of Standards and Technology) researchers working with first responders, criminal justice agencies, the military, industry and academia.

Previous work on standards for these biometric devices has focused primarily on getting different stationary and desktop systems with hardwired processing pathways to work together in an interoperable manner.

But, a new generation of small, portable and versatile biometric devices are raising new issues for interoperability.

“The proliferation of smaller devices including advanced personal digital assistants (PDAs), ultra-portable personal computers and high-speed cellular networks has made portable biometric systems a reality,” said computer scientist Shahram Orandi.

“While the portable systems have made leaps and bounds in terms of capability, there are still intrinsic limitations that must be factored into the big picture to ensure interoperability with the larger, more established environments such as desktop or large server-based systems,” he added.

The new mobile biometric devices allow first responders, police, the military and criminal justice organizations to collect biometric data with a handheld device on a street corner or in a remote area and then wirelessly send it to be compared to other samples on watch lists and databases in near real-time.

Identities can be determined quickly without having to take a subject to a central facility to collect his or her biometrics, which is not always possible.

Soldiers are beginning to use these devices to control access to secured areas, and first responders can use them to ensure that only approved workers are on-site during an incident or investigation. (ANI)

Scientists use titanium dioxide nanoparticles to kill cancer cells, sparing healthy ones

Washington, August 20 (ANI): Scientists in America have developed a way to target brain cancer cells using inorganic titanium dioxide nanoparticles bonded to soft biological material.

This achievement is a result of the joint efforts of scientists from the U.S. Department of Energy’s (DOE) and the University of Chicago’s Brain Tumor Center.

Thousands of people die from malignant brain tumours every year, and the tumors are resistant to conventional therapies.

The researchers say that their nano-bio technology may eventually provide an alternative form of therapy, which targets only cancer cells and does not affect normal living tissue.

“It is a real example of how nano and biological interfacing can be used for biomedical application. We chose brain cancer because of its difficulty in treatment and its unique receptors,” said scientist Elena Rozhkova with the DOE’s Argonne National Laboratory.

The novel approach relies upon a two-pronged approach.

The researchers describe titanium dioxide as a versatile photoreactive nanomaterial that can be bonded with biomolecules.

When linked to an antibody, they say, nanoparticles recognize and bind specifically to cancer cells.

When focused visible light is shined onto the affected region, the researchers add, the localized titanium dioxide reacts to the light by creating free oxygen radicals that interact with the mitochondria in the cancer cells.

Mitochondria act as cellular energy plants, and when free radicals interfere with their biochemical pathways, mitochondria receive a signal to start cell death.

“The significance of this work lies in our ability to effectively target nanoparticles to specific cell surface receptors expressed on brain cancer cells,” said Dr. Maciej S. Lesniak, Director of Neurosurgical Oncology at University of Chicago Brain Tumor Center.

“In so doing, we have overcome a major limitation involving the application of nanoparticles in medicine, namely the potential of these agents to distribute throughout the body. We are now in a position to develop this exciting technology in preclinical models of brain tumours, with the hope of one day employing this new technology in patients,” Lesniak added.

Using X-ray fluorescence microscopy at Argonne’s Advanced Photon Source, the researchers have also found that the tumours’ invadopodia, actin-rich micron scale protrusions that allow the cancer to invade surrounding healthy cells, can be also attacked by the titanium dioxide.

The researchers have thus far carried out tests on cells in a laboratory setting, but animal testing is planned for the next phase.

Results show an almost 100 percent cancer cell toxicity rate after six hours of illumination, and 80 percent after 48 hours.

Also, since the antibody only targets the cancer cells, surrounding healthy cells are not affected, unlike other cancer treatments such as chemotherapy and radiotherapy.

Rozhkova said that a proof of concept is demonstrated, and other cancers can be treated as well using different targeting molecules.

The expert, however, admits that the research is presently in the early stages. (ANI)

New nanocrystal shows potential for cheaper and more versatile lasers

Washington, May 11 (ANI): Scientists at the University of Rochester, along with researchers at the Eastman Kodak Company, have created a nanocrystal that constantly emits light, which has potential for the development of cheaper and more versatile lasers and brighter LED lighting.

Many molecules, as well as crystals just a billionth of a meter in size, can absorb or radiate photons. But, they also experience random periods when they absorb a photon, but instead of the photon radiating away, its energy is transformed into heat.

These “dark” periods alternate with periods when the molecule can radiate normally, leading to the appearance of them turning on and off, or blinking.

“A nanocrystal that has just absorbed the energy from a photon has two choices to rid itself of the excess energy-emission of light or of heat,” said Todd Krauss, associate professor of chemistry at the University of Rochester and lead author on the study.

“If the nanocrystal emits that energy as heat, you’ve essentially lost that energy,” he added.

Krauss worked with engineers at Kodak and researchers at the Naval Research Laboratory and Cornell University to discover the new, non-blinking nanocrystals.

Krauss and Keith Kahen, senior principal scientist of Kodak, were exploring new types of low-cost lighting similar to organic light-emitting diodes, but which might not suffer from the short lifespans and manufacturing challenges inherent in these diodes.

Kahen, with help from Megan Hahn, a postdoctoral fellow in Krauss’ laboratory, synthesized nanocrystals of various compositions.

Xiaoyong Wang, another postdoctoral fellow in Krauss laboratory, inspected one of these new nanocrystals and saw no evidence of the expected blinking phenomenon.

Remarkably, even after four hours of monitoring, the new nanocrystal showed no sign of a single blink-unheard of when blinks usually happen on a scale of miliseconds to minutes.

After a lengthy investigation, Krauss and Alexander Efros from the Naval Research Laboratory concluded that the reason the blinking didn’t occur was due to the unusual structure of the nanocrystal.

Normally, nanocrystals have a core of one semiconductor material wrapped in a protective shell of another, with a sharp boundary dividing the two.

The new nanocrystal, however, has a continuous gradient from a core of cadmium and selenium to a shell of zinc and selenium.

That gradient squelches the processes that prevent photons from radiating, and the result is a stream of emitted photons as steady as the stream of absorbed photons.

With blink-free nanocrystals, Krauss believes lasers and lighting could be incredibly cheap and easy to fabricate. (ANI)

Bamboo cultivation popularised in a big way in India’s northeast

Jorhat, May 3 (ANI): The Indian Government is encouraging bamboo cultivation in a big way in the country’s northeast region with the aim of improving the lives of local communities.

Several steps have been taken to enhance bamboo conservation and productivity in the region.

The Rain Forest Research Institute (RFRI), Jorhat, recently organised a conference to discuss ways to promote the commercial cultivation of bamboo and its management, its use as an inter-crop and the propagation of bamboo in the region.

The Rain Forest Research Institute, Jorhat, and Indian Council of Forestry Research and Education (ICFRE), Dehradun, had jointly organised the conference.

During the conference, strategies on how to develop the northeast as a center of excellence for bamboo was discussed.

“The establishment of bamboo composite center with the collaboration of one of the institute, which is located in Bangalore and here, will be demonstrating all technological aspects which are related to utilisation of bamboo. So that the local entrepreneurs and farmers of this region could be exposed to various uses of bamboo and how they could earn some money out of this bamboo enterprises,” said Jagdish Kishwan, Director General of the Indian Council of Forestry Research and Education in Dehradun.

“As a programme, our bamboo station village program, what we do that the R and D what we do here should be placed before the local people and they also understand about the bamboo propagation and application. So definitely it is going to be the exercise where the local community are involved and they are made known to the research we are doing here and how best that can help in getting additional income for them especially in bamboo and cane,” said N.K. Vasu, Director, Rain Forest research Institute in Jorhat.

Bamboo is one of the world’s most useful renewable natural resources and over 3,000 versatile uses are associated with the social, economic and cultural fabric of the north-eastern States.

Bamboo and its products can be a major potential export commodity in the northeast.

The Central Government is running a National Bamboo Mission to address issues relating to the development of bamboo and to encourage bamboo cultivation.

Farmers find bamboo cultivation quite useful.

“I took up bamboo plantation because it’s very easy, profitable and is not a time consuming job. Bamboo is used for different purposes in our region, in construction, fencing, house, manure, handicrafts etc. These days the demand of raw bamboo in the market is very high. I own 3/4 bighas of bamboo. Whenever financial need arises, I sell bamboo. I earn Rs.2-3 thousand every month. I support my family with this, ” said Jitul Gogoi, a bamboo farmer in Assam.

In northeast, bamboo is traditionally used as construction material, household articles, in handicrafts and papermaking, agriculture, fisheries, transportation and village industry.

India is home to almost 45 per cent of the world’s bamboo forest and two-third of the growing stock of bamboo in the country is available in the northeast.

136 species of bamboo are found across India, of which 89 species in north-east region only.

Bamboo cultivation and its proper utilisation are widely anticipated to benefit the local entrepreneurs and bamboo cultivators. By Vaschipem Kamodang (ANI)

NRHM’s Asha programme benefits women, child

Barolyahir (Uttar Pradesh), Apr 11 (ANI): Poor women and children in rural regions of India are availing many benefits from Asha, a scheme launched by the Government of India under the National Rural Health Mission (NRHM).

The scheme aims at spreading awareness about mother-child health. Hundreds of families of Barolyahir have gained from the services rendered by the Asha.

Under this scheme, a pregnant woman is paid Rs. 1,400, so that she can afford healthy diet and also meet other expenses.

Under the scheme, the mother and child are guided about the Anganwadi (crèche and nursery centres) as well as the need to follow-up periodical vaccination on time.

“The Central Government started this scheme for holistic motherhood. This scheme was launched for the welfare of poor and to promote scientific and healthy delivery of babies. For this, we have started Asha scheme where our women counsellors visit every house of the village.

Asha is functioning in 155 blocks in Barolyahir. They work for about 1500 families.

The women engaged in fieldwork under the scheme visit each household, and conduct survey of pregnant women in the village. They maintain a survey register. They get the pregnant women registered here and also the mid-wives for pre-natal and post-natal situation,” said Dr. Sher Singh, Medical Officer, Primary Health Centre, Barolyahir.

Women counsellors known as Ashayen (missionaries of hope) play a key role in this scheme.

They visit every household and educate the women on the vital maternal care.

“We tell them not to deliver babies at home and also not to visit private hospitals as they are expensive. We advise them to go to the government hospitals and get a benefit of Rs. 1,400. In addition, money for transportation is also given. Above all, under the scheme, both the mother and the child stay healthy,” said Veena Tomar, a member of the Asha, Barolyahir.

These mid-wife counsellors also educate the women on family planning programmes, pre and post-natal treatment, maintaining of proper hygiene and also educating the children.

The Asha has gained widespread name and fame as evident from an increasing number of women coming forth to avail the services rendered under the scheme.

Thus today, many women prefer to visit government hospitals unlike the reliance on private practitioners in the past, courtesy the versatile and integrated services of Asha. (ANI)

Nationalist Hindu leader Advani eyes India’s top post

New Delhi – Lal Krishna Advani, who fled to India from Pakistan as a refugee and emerged as the country’s top Hindu nationalist leader, has brought about a marked transformation in India’s political scene over the past two decades.

The 81-year-old leader of India’s main opposition Bharatiya Janata Party, Advani has helmed the rise of the BJP largely on the basis of Hindu-Muslim tensions and a campaign to have a Hindu temple dedicated to the Hindu god Ram built on the site of a demolished mosque in the northern city of Ayodhya.

In recent years, however, Advani, who is among India’s most versatile politicians, has attempted an image makeover from hardliner to moderate.

He has also tried to connect with young voters ahead of this year’s election, carrying out a vigorous internet campaign and writing a blog. The octogenarian recently tried out some weights at a gym in a tour aimed at youth.

A former journalist, Advani, who has been BJP president three times and a deputy prime minister, has built a reputation as an honest and strict administrator.

Born in Karachi on November 8, 1927, in what is now Pakistan, Advani started his political career in 1942 when he joined Rashtriya Swayamsewak Sangh, BJP’s ideological predecessor. He later joined the Bharatiya Jana Sangh party and was a member of Parliament from 1970 to 1975.

Advani was instrumental in making the BJP a political force, taking it from two parliamentary seats in 1984 to forming a government 15 years later. His campaign on the Ram temple catapulted his political career as well as his party’s.

Advani travelled across India to muster support for the temple, a crusade that ended with the medieval mosque being destroyed in a frenzied attack by Hindu zealots in 1992.

The demolition triggered massive riots between Hindus and Muslims that left more than 2,000 people dead. Advani has denied allegations that he incited the mobs as the temple issue is being decided by the courts.

Advani’s hardliner image was not easily acceptable to constituents during the formation of the BJP-led National Democratic Alliance government after 1996 elections, and the Ayodhya issue led to his associate, Atal Behari Vajpayee, becoming the face of the BJP.

He served as home minister in the Vajpayee cabinet and later became a deputy prime minister until the alliance’s defeat in the last elections in May 2004.

Although Advani is criticized for communal polarization in India, BJP activists claim that he put India on a high-growth trajectory and restructured India’s relations in the post-Cold War era, which saw close ties develop with the United States and Israel.

Advani was the leader of the opposition in Parliament and has held centre stage in the party as Vajpayee’s health deteriorated.

He has tried to distance himself from his hawkish image since 2005 when he praised Pakistan’s founding father, Mohammed Ali Jinnah, and described him as secular, sparking a furore in India.

Political observers said Advani has been trying to cultivate an image as a senior statesman to widen his electoral appeal in what is likely to prove his final attempt for India’s top job.

But with the BJP asserting its agenda on the temple, the party can hardly expect support from Muslims, who account for 13 per cent of India’s 1.17 billion people.

Lately, the BJP has also been faced with internal discord among its leaders as well as problems with its coalition partners, including a breakup with a powerful ally in the eastern state of Orissa.

Lacking his predecessor’s skills in keeping political alliances together, as well as fractious politics inside his own camp, Advani could fall short in his quest for the coveted post. (dpa)

Penelope Cruz turns blonde for new flick

Washington, Mar 11 (ANI): Spanish actress Penelope Cruz has turned into a blonde for her role in the upcoming drama ‘Los Abrazos Rotos’.

Director Pedro Almodovar has revealed that he did not want the actress’ trademark dark and dishevelled hairstyle for the film.

Instead, he opted for a sleek platinum blonde wig – and even managed to convince Cruz to squeeze into a red latex minidress and fishnet tights to complete her dramatic metamorphosis.

“Before beginning the tests for my film I had already decided to avoid the dishevelled styles, inspired by Sophia Loren, which suit Penelope so well. After seeing the photo from Vicky Cristina Barcelona, I was even more convinced about my decision,” Contactmusic quoted Almodovar, as saying.

“I want to try not to repeat hairstyles that Penelope has worn in other films. I really enjoy reinventing her, discovering the number of characters that reside within our beautiful and versatile leading lady,” Almodovar added. (ANI)

NASA mission to seek water ice on Moon

Washington, Feb 18 (ANI): NASA’s Lunar Crater Observation and Sensing Satellite (LCROSS), which will seek water ice on Moon, is enroute from Northrop Grumman’s facility in Redondo Beach, California, to the agency’s Kennedy Space Center in Florida in preparation for a spring launch.

The satellite’s primary mission is to search for water ice on the moon in a permanently shadowed crater near one of the lunar poles.

LCROSS is a low-cost, accelerated-development, companion mission to NASA’s Lunar Reconnaissance Orbiter, or LRO.

At Kennedy, the two spacecraft will be integrated with an Atlas V launch vehicle and tested for final flight worthiness.

LCROSS and LRO are the first missions in NASA’s plan to return humans to the moon and begin establishing a lunar outpost by 2020.

After launch, the LCROSS spacecraft and the Atlas V’s Centaur upper stage rocket will fly by the moon and enter into an elongated orbit to position the satellite for impact.

On final approach, the spacecraft and Centaur will separate.

The Centaur will strike the chosen lunar crater, creating a debris plume that will rise above the surface.

Four minutes later, LCROSS will fly through the debris plume, collecting and relaying data back to Earth before striking the moon’s surface and creating a second debris plume.

Scientists will use data from the debris clouds to determine the presence or absence of water ice.

To remain within budget and a short schedule of 26 months, the LCROSS project team developed a simple yet innovative spacecraft that uses existing NASA systems, commercial-off-the-shelf components modified to survive the harsh conditions of space, and the spacecraft design and development expertise of integration partner Northrop Grumman Space Technologies.

“LCROSS delivers a high science value per dollar,” said Steve Hixson, vice president for advanced concepts at Northrop Grumman Aerospace Systems in Redondo Beach.

“With its versatile, fast and cost efficient architecture, the LCROSS spacecraft serves as a pathfinder for future low-cost Earth and space science missions,” he added. (ANI)

Engineers design robot that would be able to better explore and investigate Mars

Washington, Feb 5 (ANI): Engineers have designed and tested a versatile, low-mass robot that can rappel off cliffs, travel nimbly over steep and rocky terrain, and explore deep craters, which might help future robotic spacecraft better explore and investigate planets such as Mars.

The robot has been designed by engineers from NASA’s Jet Propulsion Laboratory and students at the California Institute of Technology.

While Axle may help robotic spacecraft explore foreign worlds such as Mars, on Earth, it might assist in search-and-rescue operations.

“Axel extends our ability to explore terrains that we haven’t been able to explore in the past, such as deep craters with vertically-sloped promontories,” said Axel’s principal investigator, Issa A.D. Nesnas, of JPL’s robotics and mobility section.

“Also, because Axel is relatively low-mass, a mission may carry a number of Axel rovers. That would give us the opportunity to be more aggressive with the terrain we would explore, while keeping the overall risk manageable,” he added.

The simple and elegant design of Axel, which can operate both upside down and right side up, uses only three motors: one to control each of its two wheels and a third to control a lever.

The lever contains a scoop to gather lunar or planetary material for scientists to study, and it also adjusts the robot’s two stereo cameras, which can tilt 360 degrees.

Axel’s cylindrical body has computing and wireless communications capabilities and an inertial sensor to operate autonomously.

It also sports a tether that Axel can unreel to descend from a larger lander, rover or anchor point.

The rover can use different wheel types, from large foldable wheels to inflatable ones, which help the rover tolerate a hard landing and handle rocky terrain. (ANI)

Rajkot’s Paridhan Utsav 2009 promotes Khadi

Rajkot, Feb. 4 (ANI): To promote Khadi among the youth, the Khadi and Village Industries Commission (KVIC) along with the Friends’ group organized a fashion show on Monday that displayed unique creations from the traditional hand-spun fabric.

The function Paridhan Utsav 2009 witnessed some special designer collection for kids, men and women designed by Rajkot based designers.

“I have done a lot of fashion shows but this show is quiet different as Khadi garments are being displayed here and the designs are very good,” said Jimmy Nanda who won Mrs. India crown in 2007.

The show also saw Kumudben Joshi, chairperson of KVIC, walking down the ramp to promote the Khadi apparels.

“We are giving them (sales counters) their due look, new business management, new market system, we want to tap the markets in a big way so KVIC has planned a programme to build a Khadi plaza,” said Kumudben Joshi.

Used by Mahatma Gandhi against the British rule, khadi gained popularity as a symbol of simplicity and austerity.

A growing number of youngsters beyond politicians have started to wear Khadi garments to make their personal fashion statement.

Besides, the fashion glitterati are waking up to the new style quotient what the lightweight fabric offers.

The versatile Indian fabric is natural and handspun and hand woven from excellent fibers of cotton, silk and wool or a combination of at least two fibers. (ANI)

‘Khadi’ catches imagination of budding designers

Rajkot, Jan 20 (ANI): Taking cue from the latest trends of going ‘green’ budding designers in Gujarat used ‘Khadi’, an eco-friendly handspun fabric for their latest creations.

The students of fashion designing said that Khadi wears brought full circle to the days immediately preceding independence when Mahatma Gandhi had called Khadi soul of nation.

The creations by these students are to be showcased during a fashion show scheduled to coincide with the death anniversary of Mahatma Gandhi.

“People use various fabrics for their clothes, but Khadi has not been experimented with that much as yet. There are hundreds of varieties of khadi available, so we thought that we could make dresses like capri and saree. Our designs have turned out to be innovative,” said Riddhi, a fashion-designing student.

Khadi, a versatile fabric, is natural and handspun and hand woven from excellent fibres of cotton, silk and wool or a combination of at least two fibers. With the youth increasingly taking to Khadi, those who have always endorsed the fabric feel vindicated.

“We want that Khadi should be presented to the nation in a new manner. The young generation should be acquainted with the fabric. We are happy that the friends group in the city has come forward to promote Khadi. We are supporting them and these people have organised a fashion show on January 30,” said Devendra Bhai Desai, a man at a Khadi clothes shop.

‘Khadi’, was symbol of non-violent opposition to the British colonial rule. It soon became a household creation following his clarion call during freedom struggle. (ANI)

Italian artist uses chewed bubblegums to create life-size sculptures!

London, Jan 16 (ANI): Italian artist Maurizio Savini has created a series of life-size sculptures including a buffalo and a bear – using chewed bubble gums.

Savini, based in Rome, created sculptures using thousands of pieces of the bright pink gum, and have sold for as much as 40,000 pounds each.

They include a life-size buffalo, a grizzly bear and suited businessmen suspended in gymnastic poses.

The 39-year-old has been using the unusual material, known in his native Italy as ‘American Gum’ after it arrived during World War II, for the past 10 years.

His sticky sculptures have been exhibited all over the world, including London, Edinburgh, Rome and Berlin, where they have sold for as much.

“The reason I like to use chewing gum is because it seemed to me an amazingly versatile material compared to those used by the traditional arts such as painting,” the Telegraph quoted Savini, as saying.

“Despite its history of it belonging to popular culture, chewing gum does not have a statute of its own within institutional art.

“I believe that in my work on this material is redeemed and acquires a capacity and it has an expressive dignity of its own.

“I work the chewing gum when it is warm and manipulate it with a knife just like some traditional material like clay.

“The most important step is the fixing of the sculptures with formaldehyde and antibiotic,” Savini added. (ANI)

MRI proving a great boon to back pain treatment, says report

Washington, January 2 (ANI): Magnetic resonance imaging (MRI) is providing an increasing number of clinical benefits when used in the evaluation of back pain, and additional technical developments may allow it to provide even more useful orthopaedic benefits in future, according to a research article.

“Because of the many different ways to gather this important information, MRI can be used to identify or display almost every type of spinal tissue or pathology. The imaging sequence can be modified to meet many different clinical needs,” Dr. Victor M. Haughton, a radiologist at the University of Wisconsin Hospitals and Clinics, says in the article published in the Journal of the American Academy of Orthopaedic Surgeons.

The authors write that MRI—which is considered safe, fast and versatile—is being used in several spinal applications like intervertebral disk and facet joint degeneration, spinal canal stenosis, vascular disorders, and trauma.

They also suggest it to be useful for almost every spinal pathology—such as diseases of the spinal cord, nerve roots, vertebrae, disks and blood vessels.

They further say that there is no radiation risk to the patient undergoing MRI.

“The possibilities of magnetic resonance have not yet been realized. It is a rapidly evolving field. When we need tools to identify a possible herniated disk, the simplest type of MR imaging or CT imaging can be used successfully. However, if you want to find out which disk is causing pain, which nerve is firing, which metabolites are present in abnormal amounts, or how well the spinal elements are functioning, MR will provide the answers,” adds Dr. Haughton. (ANI)