Flame-spewing ‘squirts’, ‘Judgements’ helped UK win Somme battle

London, May 10 (ANI): The mystery behind Britain’s relatively fewer collateral losses during the capture of German trenches in Somme has finally been unravelled. The British employed flame spewing 56ft long, 2.5 tonne machines called “Squirts”, and “Judgements” to secure the World War One victory.

These formidable machines could rain fire as far as 300 feet. The British unleashed the force of four such killer machines on the very first day of the Somme battle, i.e. July 1st 1916.

They were built secretly in the shallow tunnels beneath the mud of no man’s land. They were operated by a crew of eight men from the Royal Engines Special Brigade – “Z” company – but took 300 men to assemble them underground, each component part being taken into the shallow tunnels, known as “Russian Saps”, in sequence. The devices then had to be filled with oil, taken underground in hundreds of cans.

According to The Telegraph, two were destroyed by German shells in the build-up to the attack and could not be operated. Two others were deployed on the morning of the assault and were credited with helping the British in those areas to capture the German trenches with comparatively few losses.

Glasgow University”s Archaeological Research Division (GUARD), is confident it has located one of the four, at Montagne de Cappy, just south of Mametz, by studying private diaries, trench maps, mine plans, aerial photographs and official accounts of the battle.

They have also conducted geophysical studies of the site, using ground penetrating radar, which have indicated the presence of metallic objects, thought to be the remains of the weapon.

The strange-looking, tubular weapons were only 14 inches wide and worked like a large syringe. A piston was pushed by compressed gas into a long chamber containing the fuel. This was then forced out through the nozzle on the surface, from where the jet of flame was projected.

For all the hours they took to assemble, the devices could only be fired three times, with each blast lasting only ten seconds.

These machines were specifically built to inspire terror in the hearts of those who had the misfortune of encountering it.

“The idea was to fill the enemy with terror. It was a weapon, not of mass destruction, but of mass terror, pure and simple. The idea was to force the Germans to keep their heads down long enough for your infantry to cross no-man”s-land,” Peter Barton, a historian and author involved in the project told the paper.

“They were meant to scare the Germans. It didn”t kill that many people. The idea was just to make them so frightened of this horrific thing. The effect of the flame was utterly stupendous. Where they were used, the British captured the German lines with very little loss at all,” he added. (ANI)

Now, painless vaccines!

it surely was too much pain, for a lot of good. Now, the trade-off is unlikely to stay current.

In what would make childhood immunisation easier and pain-free, scientists have developed a patch — the size of a postage stamp — which they claim could be used to deliver cheap, needle-free vaccines.

A new study, led by the University of Queensland, has found that a vaccine delivered by ‘Nanopatch’ induces a similarly protective immune response as a vaccine delivered by needle and syringe, but uses 100 times less vaccine.

According to the scientists, the patch could be used in developing countries where clean needles and refrigeration are scarce.

“The Nanopatch targeted specific antigen presenting cells found in a narrow layer just beneath the skin surface and as a result we used less than one hundredth of dose used by a needle while stimulating a comparable immune response.

“Our result is ten times better than the best results achieved by other delivery methods and does not require the use of other immune stimulants, called adjuvants, or multiple vaccinations.

“Because the Nanopatch requires neither a trained practitioner to administer it nor refrigeration, it has enormous potential cheaply deliver vaccines in developing nations,” lead scientist Professor Mark Kendall said.

According to the scientists, the Nanopatch comprises of several thousands of densely packed projections invisible to the human eye. The influenza vaccine was dry coated onto the projections and applied to skin of mice for two minutes.

“By using far less vaccine we believe that the Nanopatch will enable the vaccination of many more people.

When compared to a needle and syringe a Nanopatch is cheap to produce and it is easy to imagine a situation in which a government might provide vaccinations for a pandemic such as swine flu to be collected from a chemist or sent in the mail.

“This is an exciting discovery and our next step s to prove the effectiveness of Nanopatches in human clinical rials,” Professor Kendall said.

Pair to front court after drug lab find

Two people have been charged after the discovery of a drug laboratory on the Sunshine Coast.

Police allegedly found the lab on a property at Yandina yesterday.

A 36-year-old man has been charged with five offences, including possession of a dangerous drug, and a 32-year-old woman has been charged with failing to take reasonable care with a syringe and unlawful possession of glassware.

The couple are due to appear in court next month.

Man accused of hospital syringe hold-up

A 37-year-old man has been charged with aggravated robbery after allegedly trying to steal drugs at Gunnedah Hospital.

Police say the man was seeking treatment for a throat infection when he produced a syringe and threatened hospital staff about 1:00pm (AEDT).

He allegedly fled the hospital after forcing a nurse to hand over numerous ampoules of drugs from the emergency room.

The man was arrested four hours later and taken to Tamworth police station.

He was refused bail and is due to face court later today.

‘Syringe that administered fatal drugs to MJ set to be auctioned’

London, March 16 (ANI): Michael Jackson’s family is desperate to stop the syringe, used to inject drugs that killed the singer, from being auctioned, it has emerged.

Lawyers reportedly informed the King of Pop’s siblings Janet and Tito that an unnamed seller has put it up for sale.

It has been speculated that the needle may fetch a price of up to 5million dollars.

The needle is apparently doing rounds in auction houses in Vegas and may be sold off on June 25, marking the first anniversary Jackson’s death.

“This is one of the sickest lots ever put up. The syringe is no longer needed in the inquest or in Murray’s forthcoming trial but the moral implications don’t bear thinking about,” the Mirror quoted a source as saying.

The insider added: “The guy who has possession of the needle has been in meetings with his legal team, making sure it is legitimate and his to sell. The plan is to flog it for up to 5million dollars in a big Vegas casino but he’s been told he may have to sell it somewhere that doesn’t have ‘reciprocal legal agreements with the United States’, such as Brazil or even Libya.

“The validity of the sale is a matter of interpretation, dependent on whether the DA believes a crime has even been committed.

“Rumours are leaking thick and fast and the Jackson family are aware of the auction plan.

“They are furious and incensed that someone is yet again trying to profit from him. It’s an incredibly distressing time for them.”

The ‘Thriller’ hitmaker’s autopsy result had suggested he died from “lethal levels” of a powerful anaesthetic, propofol.

Jackson’s personal physician Dr. Conrad Murray has been charged for administering the drugs that eventually resulted in his death. (ANI)

No toxic substance found in Urumqui’s latest syringe attack victims’ body

Urumqui, Sep. 14 (ANI): The blood samples of Urimqui’s latest syringe attack victims showed no trace of radioactive, toxic or viral substances, such as AIDS, an expert at a Beijing-based laboratory has said.

However, Director of Disease Control and Biological Security Office with China’s Academy of Military Medical Sciences, Qian Jun, has said that the victims have showed signs of depression.

“Although no radioactive or toxic substances were found, some patients showed various levels of anxiety and depression and have been recommended for psychological counselling,” China daily quoted Quian, as saying.

Meanwhile, the first group of syringe attack suspects were prosecuted in Urumqi, capital of the Xinjiang Uygur autonomous region.

At least 500 cases of attacks have surfaced in the city since mid-August.

Two men and a woman were given sentences ranging from seven to 15 years in jail for syringe stabbings or robberies in which they threatened their victims with needles.

The court sentenced 19-year-old Yilipan Yilihamu to 15 years in prison for injecting a woman with a hypodermic needle on August 28 at a roadside fruit stall. (ANI)

Urumqi syringe attacks are ‘terror events’, say Chinese officials

New Delhi, Sep 10 (ANI): Chinese officials in Urumqi have termed the recent syringe attacks as “terror attacks”.

“They aimed to unsettle the city’s atmosphere,” said Yan Yuxing, former president of Urumqi Municipal Intermediate People’s Court.

The attacks, which targeted innocent people in the capital of northwest China’s Xinjiang Uygur autonomous region, were not practical jokes or simple crimes perpetrated by one individual but organized and planned stabbings to disturb the social order, said Du Xintao, an official with the regional Public Security Department.

Local authorities said late on Tuesday that another four suspects involved in the syringe attacks were prosecuted on Monday, bringing the number prosecuted to eight.

Police have caught 45 suspects during the scare, the China Daily reports.

To tackle the crisis, the government has posted guards in public places like buses, schools and hospitals.

The health department is treating victims. No deaths have been reported, nor have there been any cases needing anti-viral drugs, said an official with the regional center of disease control and prevention.

The government also held several press conferences and published several public notices since Sept 2 informing the public about the attacks and promising to punish the attackers.

Urumqi residents welcomed the government’s transparency over the syringe attacks. (ANI)

Syringe attacks continue in Urumqi despite death penalty warning

Urumqi (China), Sep. 9 (ANI): Despite a death penalty warning, 77 cases of needle attack were reported between Sunday and Monday evenings in Urumqi, the capital of Xinjiang Uygur autonomous region, police say.

So far, police have caught 45 suspects during the syringe scare, of whom 12 remain in police custody.

The procuratorate has approved the arrests of four. Eight people have been sent to drug rehab, according to Urumqi police authorities.

Despite signs of recovery in the city after assaults caused fear among residents and triggered mass protests, the Urumqi municipal government implemented traffic control Monday night on the city’s main streets.

Shops and businesses in the city center were ordered to close early. The control lasted from 9 pm Monday to 9 am Tuesday.

The Public Security Department of the Xinjiang Uygur autonomous region reiterated syringe attackers must be given punishment in order to protect residents and maintain social order.

The pledge followed a joint notice on Sunday of the court, the prosecutor’s office and the police bureau of Urumqi, which said an attacker may face a life sentence or even the death penalty.he department emphasized that those who stab others, no matter what means they use, are considered to have committed crimes and must be punished according to law.

Those who pretend to suffer syringe attacks and cause fear among the public will also face punishment, according to the public notice. (ANI)

Xinjiang riots: Urumqi party chief, Xinjiang police chief removed

Urumqi, Sep. 6 (ANI): In the aftermath of Xinjiang riots that erupted on July 5, the party chief of Urumqi and police chief of northwest China’s Xinjiang Uygur Autonomous Region have been sacked.

According to a decision by the CPC Xinjiang Autonomous Regional Committee, Li Zhi, secretary of the Urumqi Municipal Committee of the Communist Party of China (CPC), was replaced by Zhu Hailun.

Xinjiang’s police chief Liu Yaohua was also replaced by Zhu Changjie, party chief of Xinjiang’s Aksu Prefecture, Xinhua reports.

Fresh protests broke out this week after hundreds of Urumqi residents said that they were attacked by syringes. Five people were killed in the following protests.

Local hospitals had dealt with 531 victims of hypodermic syringe stabbings by Thursday, 106 of whom showed obvious signs of needle attacks.

Chinese military medical experts on Saturday ruled out the possibility that radioactive substance, anthrax and toxic chemical were used in recent syringe attacks in Urumqi City.

“According to the preliminary test results, such possibilities can be ruled out,” said Qian Jun, director of Disease Control and Biological Security Office with China’s Academy of Military Medical Sciences.

Samples had been sent to Beijing for further test, he added.

Xinjiang police has captured 25 suspects amid the syringe scare. (ANI)

Further unrest in west China’s Urumqi region following syringe attacks

Urumqi (China), Sep 3(ANI): Following a spate of ethnically motivated syringe attacks in China’s Xinjiang province, renewed mass demonstrations and violence was reported in the region on Thursday.

Thousands of people gathered at the residential quarter of Xiaoximen, at Renmin Cinema and Beiyuanchun farmers’ produce wholesale market and demanded security assurance from authorities, Xinhua reports.

Local Police had detained 15 people and arrested four in connection with the attacks, but it did not say what ethnic group they belonged to.

In recent weeks, ethnic-fueled violence has plagued the city, following the riots that occurred between Uyghurs, who are predominantly Muslim, and ethnic Han Chinese, the majority group in China.

Unconfirmed reports of deaths in those riots range from 200 to many more. (ANI)

Scientists imitate viruses to deliver therapeutic genes

Washington, September 1 (ANI): Australian scientists have developed a new gene therapy vector that uses the same machinery as viruses to transport their cargo into cells.

David Jans, from the Nuclear Signaling Laboratory at Monash University in Victoria, says that this achievement has raised the hope that one day therapeutic DNA will begin to be transferred to a cell’s nucleus far more efficiently than in the past, and thus there will be more effective treatments for several genetic disorders and some types of cancers.

“Through the use of proteins that mimic key functions of viruses for the packaging and transport of therapeutic DNA, we hope to improve the efficiency, and above all, the specificity of human gene therapy,” he said.

“Following the creation of efficient, specific and safe DNA delivery vectors, the challenges in human gene therapy will be able to move on from questions of delivery to actual clinical application,” he added.

A gene therapy vector is used to deliver a therapeutic gene or a portion of DNA into a cell nucleus similar to how a syringe is used to inject medicines.

To create the new gene therapy vector, Jans and his colleagues used pieces of different genes to create a protein called a “modular DNA carrier”, which can be produced by bacteria.

Writing about their work in The FASEB Journal, the researchers have revealed that this protein carries and delivers therapeutic DNA to a cell’s nucleus, where it reprograms a cell to function properly.

While experimenting in their laboratory, the research team combined these carrier proteins with therapeutic DNA, and attached them to cell membrane receptors and the nuclear import machinery of target cells.

In turn, according to the researchers, the packaged DNA moved into the cell through the cytoplasm and into the nucleus.

“Effective gene therapy is clearly the best way to treat heritable diseases. It’s also an approach to other diseases where the environment or infection messes up our genes.” said Dr. Gerald Weissmann, the Editor-in-Chief of The FASEB Journal.

“The Australians have worked out how viruses identify our nuclear ZIP-code, and have delivered therapeutic genes to the same address. This work opens up a new era of pharmaceutical development,” Dr. Weissmann added. (ANI)

Jackson’s doctor denies giving potent painkillers before death

London, June 29 (ANI): Michael Jackson’s personal doctor has denied that he gave a shot of potent painkiller Demerol before the star collapsed in his home.

Dr. Conrad Murray was quizzed for three hours by the Los Angeles Police Department on June 27.

Murray is also believed to have plunged a syringe into Jackson’s heart in his failed attempts to save him.

But, according to his lawyer Edward Chernoff, Murray has told investigators that, contrary to reports, he did not give the King of Pop the powerful painkillers in the hours before his death on June 25.

“There was no Demerol. No OxyContin,” Sky News quoted Chernoff as having told the LA Times.

Homicide detectives probing into the death insist that it is not a criminal investigation, and that they interviewed Murray to know what happened in the finals moments of Jackson’s life.

Spokeswoman Miranda Sevcik said in a statement: “Investigators say the doctor is in no way a suspect and remains a witness to this tragedy.”

She added: “The impression that he has been hiding from authorities, that’s not correct.”

The coroner’s examination recently ruled out foul play, though the exact cause of the death has yet to be determined.

A spokesman confirmed Jackson was on prescription medicine, but refused to say whether that might have led to the singer’s demise.

The Jackson family reportedly carried out their own private second autopsy to gather evidence for a legal battle if no one is charged over the tragedy. (ANI)

Unconscious Jackson still had pulse when doctor found him

New York, June 29 (ANI): Michael Jackson’s personal doctor has told officials that the King of Pop was unconscious when he reached him but still had a pulse, according to the doctor’s lawyers.

Dr Conrad Murray was quizzed for three hours by the Los Angeles Police Department on June 27.

He is suspected of injecting the singer with the potent painkiller Demerol before the star collapsed in his home.

Murray is also believed to have plunged a syringe into Jackson’s heart in his failed attempts to save him.

But, according to his lawyer Matthew B. Alford, Murray has told investigators that, contrary to reports, he did not give the 50-year-old the powerful painkillers in the hours before his death on June 25.

“He doesn’t know what caused this,” the New York Times quoted Alford as saying.

Homicide detectives investigating the death have insisted it is not a criminal investigation, and that they interviewed Murray to know what happened in the finals moments of Jackson’s life.

The coroner’s examination recently ruled out foul play though the exact cause of the singer’s death is yet to be determined.

A spokesman confirmed that Jackson was on prescription medicine, but refused to say whether that might have led to the singer’s demise.

The Jackson family reportedly carried out their own private second autopsy to gather evidence for a legal battle if anybody found to be responsible was not brought to justice. (ANI)

Criminal investigation launched into Jackson’s death

London, June 29 (ANI): A criminal investigation has been launched into the sudden death of Michael Jackson, his family’s lawyer has revealed.

Attorney Brian Oxman said that homicide detectives had been called in to investigate the death, and the Jackson family was looking to begin a legal battle of their own if anybody found to be responsible was not brought to justice.

The family carried out their own private second autopsy to gather evidence to start legal action, after foul play was ruled out in the first one.

“I can tell you, and this is a new development, there is a criminal investigation taking place by the Los Angeles Police Department. That is the case. They have told the family,” British tabloid The Sun quoted Oxman as saying.

The King of Pop’s personal doctor Conrad Murray was questioned by the Los Angeles Police Department (LAPD) on June 27.

Murray is suspected of giving the singer a shot of the potent painkiller Demerol before he collapsed in his rented Los Angeles home.

He is thought to have plunged a syringe into the star’s heart in his failed attempts to save him.

Speaking about Murray, Oxman added: “I don’t know what he did. But the reports I have heard are disturbing. A Demerol shot sure sounds consistent with what I knew.”

A police spokesman said: “Dr Conrad Murray voluntarily contacted the Los Angeles Police Department. Detectives assigned to Robbery and Homicide Division met with him and conducted an extensive interview. Dr Murray was co-operative and provided information which will aid the investigation.” (ANI)

Now, painless nanoneedles to deliver drugs to cell organelles directly

Washington, May 23 (ANI): Always dreaded those moments when the doctor got that syringe ready to painfully jab it into your arm? Well, not anymore, for scientists have now designed gold-plated nanoneedles that can deliver the medicine right into the tiny organs of cells and that too without causing any pain.

Thinner than a human hair, the new nanoneedle distributes molecules directly to the right organelles, doing away with the problem of the cell organelles’ failure to collect and use drugs released into the bloodstream.

“What we have here, is a powerful tool for delivering a very tiny amount of drugs into cells that have initially been removed from the body and can-after being injected by the nanoneedle-be placed back into the body for tracking, diagnosing, and treatment of illness,” National Geographic News quoted study co-author Min-Feng Yu, a University of Illinois molecular biologist, as saying.

However, the idea of a nanoneedle isn’t as new as it seems, for scientists have long been trying to use tiny syringes to inject cells.

But needles, developed earlier, have been relatively clumsy, damaging cells as they poked them.

Thus, to avoid building a squirting tube, the researchers designed a solid needle that didn’t need to be hollow and was cell-friendly 50 nanometres wide.

Tiny particles are attached to the nanoneedle’s thin outer layer of gold via “linker” particles. After entering an organelle, the nanoneedle releases the particles.

The researchers have said that designing nanoneedles that can be programmed to target multiple cells and automatically deliver drugs into those cells at the same time, could mean that there may be a day when nanoneedles needn’t be rocket science.

The findings have been published online by the journal Nano Letters. (ANI)

How Salmonella survives in environment

Washington, Mar 24 (ANI): Researchers at University of Liverpool have shown how a single-celled organism, living freely in the environment, could be a source of Salmonella transmission to animals and humans.

Salmonella are microscopic living creatures that can contaminate almost any food type, causing diarrhoea, abdominal pain and fever.

Scientists know that Salmonella – which can also cause typhoid fever – has evolved unique mechanisms to prevent the body’s immune system from functioning effectively, but until now it was not understood how it survives so successfully in the environment.

Now, Liverpool scientists, in collaboration with the Institute for Animal Health, have demonstrated that Salmonella use a secretion system to protect themselves inside amoeba – a single-celled organism living on land and in the water.

Their study suggests that amoeba may be a major source of Salmonella within the environment and could play a significant role in transmission of infection to man and animals.

Salmonella uses a system, called SP12 type III, which acts as a bacterial machine inside organisms and causes disease in humans, animals and plants.

The system employs a ‘syringe-like’ mechanism to inject bacteria into cells that would normally release compounds to rid the body of harmful substances.

This system changes the structure of the cell and prevents these compounds from coming into contact with pathogens and destroying them.

“Salmonella has managed to survive extremely successfully in the environment, finding its way into our food and causing illness, despite the body’s best efforts to fight it off. We found that it uses a system, which operates, in the human immune system as well as inside amoeba living in the environment. This system essentially protects Salmonella within cellular compartments, called phagosomes, where it can survive and multiply,” Dr Paul Wigley, from the National Centre for Zoonosis Research, based at the University’s Leahurst campus, said.

“Its ability to survive in amoeba is a huge advantage to its continued development as it may be more resistant to disinfectants and water treatment. This means that we need to work to understand ways of controlling amoeba in water supplied to animals and prevent it acting as a ‘Trojan Horse’ for Salmonella and other pathogens,” he added. (ANI)

Used-syringe racket busted in Ahmedabad

Ahmedabad, Feb. 27 (ANI): The Municipal Corporation of Ahmedabad on Friday considered several raids across the city and recovered huge quantities of used syringes and other medical wastes, suspected to be the reason behind the recent Hepatitis B outbreak.

District health officials and police raided various go-downs of scrap dealers. Five go-downs were sealed from where a large quantity of used syringes, needles and bio-medical wastes were found.

According to health officials, the scrap dealers used to purchase used syringes and biomedical wastes from doctors in hepatitis-hit Modasa town.

“When the drugs department raided various warehouses in Modasa, a suspected person told us that they used to collect medical wastes from the doctors and they used to distribute it in Ahmedabad,” said Chetan Khurana, Sub Inspector, Asarva Police Station.

The dealers were booked on Wednesday night by Gujarat police.

Modasa, and some other adjoining areas are battling the Hepatitis-B epidemic. The recent exposure of the deadly syringe racket that first hoards medical waste and then sells-seems to be the reason behind the quick spreading of the disease in the state. (ANI)

Used-syringe racket busted in Ahmedabad

Ahmedabad, Feb. 27 (ANI): The Municipal Corporation of Ahmedabad on Friday considered several raids across the city and recovered huge quantities of used syringes and other medical wastes, suspected to be the reason behind the recent Hepatitis B outbreak.

District health officials and police raided various go-downs of scrap dealers. Five go-downs were sealed from where a large quantity of used syringes, needles and bio-medical wastes were found.

According to health officials, the scrap dealers used to purchase used syringes and biomedical wastes from doctors in hepatitis-hit Modasa town.

“When the drugs department raided various warehouses in Modasa, a suspected person told us that they used to collect medical wastes from the doctors and they used to distribute it in Ahmedabad,” said Chetan Khurana, Sub Inspector, Asarva Police Station.

The dealers were booked on Wednesday night by Gujarat police.

Modasa, and some other adjoining areas are battling the Hepatitis-B epidemic. The recent exposure of the deadly syringe racket that first hoards medical waste and then sells-seems to be the reason behind the quick spreading of the disease in the state. (ANI)

Now, blood jabs that help athletes beat injury

London, Feb 22 (ANI): Injecting athletes with their own blood can speed recovery from a whole range of sporting injuries, say scientists.

The procedure – known as platelet-rich plasma therapy (PRPT) – dates back to the 1970s and has previously been used in orthopaedic surgery in hospitals to help mend broken bones.

Sports docs reckon its use is so well tested that it could be deployed as a rapid healing trick for a number of sporting injuries without the need for surgery, reports The Times.

The process involves blood being withdrawn with a syringe, then spun in a centrifuge to isolate the body-healing platelets which are then injected into the damaged tissue.

Research has found that athletes who undergo the treatment report functional recovery in half the time expected.

In one study 15 of 20 patients with tennis elbow – and contemplating surgery were given PRPT; the other five relied on anaesthetic.

Two months later the patients receiving the therapy reported a 60 percent reduction in pain compared with only 16 percent for the others. (ANI)

Microchips to identify elephants in Jim Corbett National Park

Jim Corbett National Park, Jan 21 (ANI): Elephants in Jim Corbett National Park in Uttarakhand have been installed with microchips, which will act as their identification proof.

Installed with the help of a syringe, these chips will help the authorities identify the elephants from among the wild ones.

The chips would provide a unique identification number to the elephants, which would enable the wildlife authorities at the park, to keep a track on these elephants through the means of a digital reader.

The chips would also ensure that the owner of the elephants, which are used to ferry visitors around the park, do not exchange their old and ailing jumbos with another elephant.

“The microchip gives a unique identification number to the elephant. The chances of that animal mixing with others and even the owners exchanging their animals with other elephants are reduced,” said DS Rawat, Warden, Jim Corbett National Park.

The authorities at the park would only allow the elephants installed with microchips to take the visitors for a trip around the park.

So far around 17 elephants have been installed with these microchips and many more are in queue to get their digital identification. By Vipul Goel (ANI)