Farmers grew rice in China’s Yangtze Basin 4,000 years ago

Washington, September 18 (ANI): New findings in the form of carbonized rice have indicated that farming in the Yangtze Basin in China existed as early as 4,000 years ago.

According to a report in Epoch Times, excavation in the Xiezi Area of Hubei Province yielded a total of 402 cultural relics, including carbonized rice.

Stone tools, pottery, bronze, jade and porcelain were unearthed, as well as a number of spinning wheels, drop spindles made of clay and other textile tools.

There were also stone mounds and smelting relics such as slag.

A variety of grains and seeds were found, and experts believe there may be carbonized wheat among the plant findings at the site.

The relics were determined to be from the Neolithic Era or New Stone Age at the time of the Shang Dynasty (ca. 1600-1050 B.C.) and Western Zhou Dynasty (ca. 1046-771 B.C.)

The combination of the relics that were found and their stratigraphic age provides valuable information about the diet structure, production methods, and living conditions of the inhabitants of the area during the time of the Shang and Western Zhou dynasties.

Archeological team leader, Luo Yunbin explained that there had been speculation in the past about edible rice production in the Yangtze Basin, but the new findings provide solid physical evidence that there was agricultural development in that area during ancient times. (ANI)

Holiday Inn hotel made of key cards is world’s first

Melbourne, Sep 18 (ANI): A Holiday Inn hotel made entirely of key cards has been unveiled in New York.

The 37-square-metre hotel, built by world record-holding Cardstacker Bryan Berg, is made from more than 200,000 key cards and weighs 1814 kilograms.

It includes a guest bedroom, bathroom and lobby, with life-sized furniture.

The design was created by Holiday Inn, the world’s largest hotel group, to mark the relaunch of 1200 of its hotels around the world.

“The Key Card Hotel is a fun and interactive way to showcase the changes happening at our hotels and is the only structure of its kind to ever be created by a hotel brand,” News.com.au quoted Kevin Kowalski, Senior Vice President, Global Brand Management, Holiday Inn, as saying.

Berg, who will also build a freestanding three-metre replica of New York’s Empire State Building in the lobby of the Key Card Hotel using Holiday Inn playing cards, said constructing the hotel has been a great challenge.

“This is my largest cardstacking challenge to date and the only card creation I have ever made at full human scale,” Berg added about the hotel.

The first 250 guests who attended the Key Card Hotel grand opening received a free night stay at any Holiday Inn.

The company’s 1 billion dollar relaunch is one of the largest in the history of the hospitality industry. (ANI)

Archaeologists discover gemstone carrying portrait of Alexander the Great

Washington, September 16 (ANI): An archaeological team, during excavations in Israel, has discovered a gemstone that has a portrait of Alexander the Great engraved on it.

The excavations at Tel Dor were carried out by an archaeological team, which was directed by Dr. Ayelet Gilboa of the University of Haifa and Dr. Ilan Sharon of the Hebrew University of Jerusalem.

“Despite its miniature dimensions – the stone is less than a centimeter high and its width is less than half a centimeter – the engraver was able to depict the bust of Alexander on the gem without omitting any of the ruler’s characteristics,” said Dr. Gilboa, Chair of the Department of Archaeology at the University of Haifa.

“The emperor is portrayed as young and forceful, with a strong chin, straight nose and long curly hair held in place by a diadem,” he added.

The Tel Dor researchers have noted that it is surprising that a work of art such as this would be found in Israel, on the periphery of the Hellenistic world.

“It is generally assumed that the master artists – such as the one who engraved the image of Alexander on this particular gemstone – were mainly employed by the leading Hellenistic courts in the capital cities, such as those in Alexandria in Egypt and Seleucia in Syria,” according to the researchers.

“This new discovery is evidence that local elites in secondary centers, such as Tel Dor, appreciated superior objects of art and could afford ownership of such items,” they added.

The significance of the discovery at Dor is in the gemstone being uncovered in an orderly excavation, in a proper context of the Hellenistic period.

This tiny gem was unearthed by a volunteer during excavation of a public structure from the Hellenistic period in the south of Tel Dor, excavated by a team from the University of Washington at Seattle headed by Prof. Sarah Stroup.

Dr. Jessica Nitschke, professor of classical archaeology at Georgetown University in Washington DC, identified the engraved motif as a bust of Alexander the Great.

This has been confirmed by Prof. Andrew Stewart of the University of California at Berkeley, an expert on images of Alexander and author of a book on this topic.

Alexander was probably the first Greek to commission artists to depict his image – as part of a personality cult that was transformed into a propaganda tool. (ANI)

Spanking found to have negative effects on low-income toddlers

Washington, September 16 (ANI): Spanking negatively affects the behaviour of toddlers in low-income families, according to a new study.

Published in the journal Child Development, the longitudinal study looked at how low-income parents discipline their young children.

It showed that spanking 1-year-olds leads to more aggressive behaviours and less sophisticated cognitive development in the next two years.

Verbal punishment, however, was not found to be associated with such effects, especially when it was accompanied by emotional support from mothers.

Besides, 1-year-olds’ fussiness predicted spanking and verbal punishment at ages 1, 2, and 3.

The study explored whether mothers’ behaviours lead to problematic behaviour in children, whether children’s challenging behaviours elicit harsher discipline, or both.

It looked at more than 2,500 exclusively low-income White, African American, and Mexican-American mothers and their young children, interviewing and observing them at home when the children were 1, 2, and 3 years old.

All participants’ family incomes were at or below the federal poverty level.

Using their own interpretations of spanking, mothers reported how often anyone in the home had spanked their children in the past week.

The study also looked at how often mothers verbally punished-scolded, yelled, or made negative comments-their children.

It showed that African American children were spanked and verbally punished significantly more than the other children in the study.

The authors speculated that that might be due to cultural factors, such as belief in the importance of children’s respect for elders and in the value of physical discipline to instil that respect.

Moreover, some African American mothers said that in preparing their children for a harsh, physically dangerous, and racially discriminating world, there was little room for error in their childrearing.

The study also shed light on information about the effects of such types of discipline.

“Our findings clearly indicate that spanking affects children’s development,” said Lisa J. Berlin, research scientist at the Center for Child and Family Policy at Duke University and the study’s lead author.

Specifically, children who were spanked more often at 1 behaved more aggressively when they were 2, and had lower scores on tests measuring thinking skills when they were 3.

Similar findings were made even after taking into consideration such family characteristics as mothers’ race and ethnicity, age, and education; family income and structure; and the children’s gender.

The study also found that children who were more aggressive at age 2, and had lower cognitive development scores at ages 1 and 2, were not spanked more at ages 2 and 3.

“So the mothers’ behaviours look more influential than the children’s,” said Berlin.

Unlike spanking, however, verbal punishment alone didn’t affect either children’s aggression or their cognitive development.

Interestingly, when verbal punishment was accompanied by emotional support from moms, the children did better on the tests of cognitive ability. (ANI)

New air filter system can destroy up to 99.9 per cent of bugs on aircraft

London, September 16 (ANI): British researchers have developed an air filter system that destroys up to 99.9 per cent of infectious viruses and bacteria as well as pollutants that can circulate in the confines of an aircraft, especially on long-haul flights.

According to a report in The Times, the machine has been developed by aerospace giant BAE Systems, in collaboration with Quest International, a small company based in Cheadle, South Manchester, UK.

The device, called AirManager, uses a controlled electric field to filter out and destroy any airborne particles or germs as they pass through an aircraft’s air conditioning system, emitting only clean, sterilized air.

After four years of development and tests, BAE says it has received its first orders from a major European airline and announced the technology is also being considered for use in NHS hospitals as a way to stop the spread of “superbugs” such as MRSA and Clostridium difficile.

The air on board a passenger jet must be pressurized in order for passengers to be able to breathe, but scientists and lobby groups have previously claimed that passengers can be exposed to toxins as a result of the “bleed air” system that is used to redirect air from the engines to the cabin and cockpit.

Air inside the cabin is then circulated and re-circulated up to 30 times an hour, far more than in conventional air conditioning systems, meaning that infectious viruses and bacteria can quickly spread.

Unlike conventional filters, which are designed to sieve out particles from the air as it passes through perforated barriers at high speed, David Hallam, an engineer and founder of Quest International, said that the AirManager used an “avalanche of electrons” emitted in a closed electric field to break down and destroy the atomic structure of any pollutants or germs.

“This works with swine flu, avian flu, norovirus, MRSA, even a modified form of anthrax,” Hallam said.

Hallam said that he originally designed the “close coupled field” in the late 1990s to rid nursing homes of biological odours caused by bacteria.

But, the filter was later found to have an effect in reducing the airborne transmission of bacteria such as MRSA (methicillin-resistant Staphylococcus aureus) and Clostridium difficile.

BAE Systems expressed interest in the technology four years ago for use on aircraft and the system was recently tested on the flight deck and cabin air systems of Boeing 757 and Avro RJ passenger jets by five European airlines, with successful results. (ANI)

Gene linked to male infertility identified

Washington, Sept 16 (ANI): Scientists from Virginia Commonwealth University have identified a gene that may contribute to male infertility.

The research team hopes that the new findings would lead to new approaches to male contraception.

Sperm are produced in the testicles through a three-step process called spermatogenesis.

During the final stage, known as spermiogenesis, a lot of changes take place, including the packaging of DNA into the sperm head and the formation of the sperm tail, which propels the sperm cell toward the egg.

The study conducted using mouse model showed that mice lacking a protein called meiosis expressed gene 1, or MEIG1, were sterile as a result of impaired spermiogenesis – the process that encompasses changes in the sperm head and the formation of the tail.

The team also found that MEIG1 associates with the Parkin co-regulated gene protein, or PACRG protein, and that testicular PACRG protein is reduced in MEIG1-deficient mice.

PACRG is thought to play a key role in assembly of the sperm tail, and the reproductive phenotype of PACRG -deficient mice mirrors that of the MEIG1-mutant mice.

“We discovered that MEIG1 is essential for male fertility. Moreover, our findings reveal a critical role for the MEIG1/PACRG partnership in the function of a structure that is unique to sperm, the manchette. The absence of a normal manchette in mice lacking MEIG1 totally disrupts the maturation process of sperm,” said Dr Jerome F. Strauss III, dean in the VCU School of Medicine.

“In addition to having an impact on fertility, the discovery identifies a new target for drug discovery for a much needed reversible male method of contraception,” he added.

The study is published in the Early Edition of the Proceedings of the National Academy of Sciences. (ANI)

Some animals can reflect upon, monitor, regulate their states of mind

Washington, September 15 (ANI): Conducting extensive research into animal cognition, psychologists at the University at Buffalo have found that some animals may share humans’ ability to reflect upon, monitor or regulate their states of mind.

“Comparative psychologists have studied the question of whether or not non-human animals have knowledge of their own cognitive states by testing a dolphin, pigeons, rats, monkeys and apes using perception, memory and food-concealment paradigms,” said Dr. J. David Smith, a comparative psychologist at the university.

“The field offers growing evidence that some animals have functional parallels to humans’ consciousness and to humans’ cognitive self-awareness,” he added.

He counts dolphins and macaque monkeys among such species.

Recounting the original animal-metacognition experiment with Natua the dolphin, Smith said: “When uncertain, the dolphin clearly hesitated and wavered between his two possible responses, but when certain, he swam toward his chosen response so fast that his bow wave would soak the researchers’ electronic switches.”

He added: “In sharp contrast, pigeons in several studies have so far not expressed any capacity for metacognition. In addition, several converging studies now show that capuchin monkeys barely express a capacity for metacognition. This last result,” Smith says, “raises important questions about the emergence of reflective or extended mind in the primate order. This research area opens a new window on reflective mind in animals, illuminating its phylogenetic emergence and allowing researchers to trace the antecedents of human consciousness.”

Smith describes metacognition as a sophisticated human capacity linked to hierarchical structure in the mind because the metacognitive executive control processes oversee lower-level cognition, to self-awareness because uncertainty and doubt feel so personal and subjective, and to declarative consciousness because humans are conscious of their states of knowing and can declare them to others.

Therefore, Smith says: “It is a crucial goal of comparative psychology to establish firmly whether animals share humans’ metacognitive capacity. If they do, it could bear on their consciousness and self-awareness, too.”

He concludes, “Metacognition rivals language and tool use in its potential to establish important continuities or discontinuities between human and animal minds.”

A research article describing his study has been published in the journal Trends in Cognitive Science. (ANI)

Research team all set to explore sacred Maya pools of Belize

Washington, September 14 (ANI): A team of expert divers, a geochemist and an archaeologist is all set to become the first to explore the sacred pools of the southern Maya lowlands in rural Belize.

The expedition, made possible with a grant from the National Geographic Society and led by a University of Illinois archaeologist, will investigate the cultural significance and environmental history and condition of three of the 23 pools of Cara Blanca, in central Belize.

Called ‘cenotes’, these groundwater-filled sinkholes in the limestone bedrock were treated as sacred sites by the Maya, according to University of Illinois archaeologist Lisa Lucero, who will lead the expedition next spring.

“Any openings in the earth were considered portals to the underworld, into which the ancient Maya left offerings,” said Lucero. “We know from ethnographic accounts that Maya collected sacred water from these sacred places, mostly from caves,” she added.

Studies of shallow lakes and cenotes in Mexico and Guatemala have found that the Maya also left elaborate offerings in the sacred lakes and pools.

Items found on the bottom of lakes in these regions include masks, bells, jade, human remains, figurines and ceramic vessels decorated with animals, plants and the gods of fertility and death.

“Diving the sacred pools of Cara Blanca, in central Belize, is necessary to determine if they have similar sacred qualities,” Lucero said.

“Once underwater, we will first have to cut out some of the jungle wood so that we can even reach the bottom,” said Patricia Beddows, a lecturer of earth and planetary sciences at Northwestern University and an expert diver who has explored cenotes on the Yucatan Peninsula of Mexico.

“After mapping for fragile Maya artifacts, we will also take water data and manually drill sediment cores,” she added.

“The sediment samples will provide a record of changes in surface and water conditions,” Beddows said.

“Were the Maya challenged by droughts in the area? Did the water quality suddenly go bad due to sulfur or other geologic factors? We hope these cenotes will provide a rich story of linked human and environmental conditions,” she said.

One of the three pools the researchers will explore has a substantial Maya structure on its edge, likely ceremonial.

Preliminary investigations of the structure conducted by archaeologist Andrew Kinkella, of Moorpark College, turned up a lot of jars and the fragments of jars.

“This could indicate that the site was important for collecting sacred water,” Lucero said. (ANI)

Scientists make first high-resolution 3D images of a polymer solar cell’s insides

Washington, September 14 (ANI): Researchers from the Eindhoven University of Technology and the University of Ulm in Germany have made the first high-resolution 3D images of the inside of a polymer solar cell.

This gives them important new insights in the nanoscale structure of polymer solar cells and its effect on the performance.

The investigations shed new light on the operational principles of polymer solar cells.

These solar cells do not have the high efficiencies of their silicon counterparts yet. Polymer cells, however, can be printed in roll-to-roll processes, at very high speeds, which makes the technology potentially very cost-effective.

Added to that, polymer cells are flexible and lightweight, and therefore suitable to be used on vehicles or clothing or to be incorporated in the design of objects.

In these hybrid solar cells, a mixture of two different materials, a polymer and a metal oxide are used to create charges at their interface when the mixture is illuminated by the sun.

The degree of mixing of the two materials is essential for its efficiency.

Intimate mixing enhances the area of the interface where charges are formed but at the same time obstructs charge transport because it leads to long and winding roads for the charges to travel.

Larger domains do exactly the opposite.

The vastly different chemical nature of polymers and metal oxides generally makes it very difficult to control the nanoscale structure.

The Eindhoven researchers have been able to largely circumvent this problem by using a precursor compound that mixes with the polymer and is only converted into the metal oxide after it is incorporated in the photoactive layer.

This allows better mixing and enables extracting up to 50 percent of the absorbed photons as charges in an external circuit.

The importance of the degree of mixing was clearly demonstrated by visualization of the structure of these blends in three dimensions.

Traditionally such visualization has been extremely challenging, but by using 3D electron tomography, the team has been able to resolve the mixing with unprecedented detail on a nanoscale.

From these images, the researchers at the Institute of Stochastics in Ulm have been able to extract typical distances between the two components, relating to the efficiency of charge generation, and analyze the percolation pathways, that is, how much of each component is connected to the electrode.

These quantitative analyses of the structure matched perfectly with the observed performance of the solar cells in sunlight. (ANI)

World’s most advanced CT scanner to see through solids

Washington, September 11 (ANI): Researchers at The University of Nottingham, UK, have created the most advanced 3D X-ray micro Computed Tomography (CT) scanner in the world, which will help scientists from a wide variety of departments across the University literally see through solid materials, including soil.

Known as the ‘Nanotom’, the machine will make previously difficult and laborious research much easier as it allows researchers to probe inside objects without having to break into them.

The Nanotom will produce high-resolution 3D and slice images of solids with a pixel resolution of up to half micron or 500 nanometres.

It will be based at the School of Biosciences as the centrepiece of research into efforts to understand the microscopic interactions between plant root growth and soil structure.

The first project to use it will examine the sensing ability of roots to grow in the best direction for the health of the plant through the soil.

It aims to provide evidence of how the root reacts and adapts to soil stresses like drought and compaction by adjusting the genetic information in the tips of the root as it grows.

The Nanotom will allow researchers to follow the progress of the root growth and soil structural development for the first time without disturbing the sample of the plant growing in the soil.

The eventual aim of research like this is to contribute to worldwide efforts for food security and sustainable food production by preserving and improving the vital but finite soil resources of the planet.

It will enable scientists to come up with a recipe for the best soil composition and level of compaction as well as informing plant breeding programmes.

Accurate soil structure measurement will be also be essential in changing farming practices to cut CO2 which is released into the atmosphere during traditional ploughing of agricultural soil.

According to Dr Sacha Mooney from the University’s Division of Agricultural and Environmental Sciences, “This new kit will completely revolutionize our work in trying to understand the key factors that control some of the many functions that soils perform.”

“Of course it’s not just soils we’ll be scanning, I think I am just as excited about the opportunity to look inside newly created environmental building materials, eco-friendly crops developed to improve yield and even chocolate bars for the food industry,” Mooney added. (ANI)

Silk made by common Australian green lacewing toughest: Study

Melbourne, September 10 (ANI): A new research has found that Australian lacewings build tougher silk than silkworms.

Scientists at CSIRO Entomology have learnt that silk made by the common Australian green lacewing can be stretched up to six times further than silkworm silk.

Moreover, its unusual structure makes it potentially much easier to manufacture artificially.

The common Australian green lacewing (Mallada signata) produces silk to create tiny stiff stalks to hold each of its eggs on.

The insect pushes out a liquid drop of silk dope before stretching it out to the point at which it stiffens and then placing the egg safely on top.

Researchers found that the lacewing silk was different from the silk created by other insects and had had its own evolutionary pathway.

Unlike the plank-like structure of other silks from spiders or silkworms, lacewing silk contains two fibrous proteins structured like a concertina door, giving it extra toughness and elasticity.

According to Dr Tara Sutherland, who was part research team, the lacewing silk protein is also shorter and less repetitive, making it easier to reproduce artificially by fermentation in bacteria.

“Silks are made under benign conditions. They’re made at room temperature, from an aqueous system and from readily replaced building blocks, so it’s a very environmentally friendly process, in contrast to the synthetic equivalents,” ABC Science quoted Sutherland as saying.

She added: “The material has a lot of strength and it’s very, very light so it’s quite remarkable. It’s also very tough.”

Apart from the traditional textile uses, the biocompatibility of the natural fibre allows this kind of silk to be used in high-tech medical applications such as providing the scaffolding for growing new human cells on.

The research will be published in the Journal of Structural Biology. (ANI)

Long working hours make parents compromise on food choices

Washington, Sept 10 (ANI): Long work hours and irregular schedules are forcing people to compromise on food choices for themselves and their children, suggests a new study.

The research team from Cornell University measured food choice coping strategies in low- to middle-income families in five categories: (1) food prepared at/away from home; (2) missing meals; (3) individualizing meals (family eats differently, separately, or together); (4) speeding up to save time; and (5) planning.

They found that fathers who worked long hours or had nonstandard hours and schedules were more likely to use take-out meals, miss family meals, purchase prepared entrees, and eat while working.

Similarly, mothers were also likely to purchase restaurant meals or prepared entrees or missed breakfast.

About a quarter of mothers and fathers said they did not have access to healthful, reasonably priced, and/or good-tasting food at or near work.

The findings suggest that better work conditions may be associated with more positive strategies such as more home-prepared meals, eating with the family, keeping healthful food at work, and less meal skipping.

“This study examined how work conditions are related to the food choice coping strategies of low- and moderate-income parents,” said Dr Carol M. Devine, RD, Division of Nutritional Sciences, Cornell University, and colleagues.

“Study findings will enhance understanding of social and temporal employment constraints on adults’ food choices and may inform workplace interventions and policies…The importance of work structure for employed parents’ food choice strategies is seen in the associations between work hours and schedule and food choice coping strategies, such as meals away from home and missed family meals.

“Long work hours and irregular schedules mean more time away from family, less time for household food work, difficulty in maintaining a regular meal pattern, and less opportunity to participate in family meals; this situation may result in feelings of time scarcity, fatigue, and strain that leave parents with less personal energy for food and meals,” the researchers added.

The study appears in the Journal of Nutrition Education and Behavior. (ANI)

How addictive drugs influence learning and memory

Washington, Sep 10 (ANI): In a new study on mice, researchers have found why and how the use of addictive drugs take control of reward signals and influence neural processes associated with learning and memory.

The study could help explain how drug-associated memories, such as the place of drug use, drive and perpetuate the addiction.

It is known that the neurochemical dopamine, a key player in the brain’s reward system, is involved in the process of addiction.

Research has indicated that dopamine participates in neural processes associated with learning, such as the strengthening of neuronal connections, called synaptic potentiation.

Evidence has also implicated the hippocampus, a deep-brain structure that is critical for formation of new memories, in the development of drug addiction.

“Although addictive drugs like nicotine have been shown to influence the induction of synaptic potentiation, there has been little or no research in freely moving animals that monitors ongoing induction of synaptic potentiation by a biologically relevant drug dose,” explains senior author Dr. John Dani from the Department of Neuroscience at the Baylor College of Medicine in Houston, Texas.

The researchers recorded from the brains of freely moving mice while applying physiologically relevant concentrations of nicotine, the addictive component in tobacco.

The researchers found that nicotine induced synaptic potentiation correlated with the mice learning to prefer a place associated with the nicotine dose.

Importantly, these effects required a local dopamine signal within the hippocampus.

The finding reinforces the view that dopamine enables memory for specific events.

Overall, the results point to some intriguing possibilities about how drug-associated memories might contribute to behaviors associated with addiction.

“An animal’s memories or feelings about the environment are updated when the dopamine signal labels a particular event as important, new, and salient. Normally these memories help us to perform successful behaviors, but in our study, those memories were linked to the addictive drug.

When specific environmental events occur, such as the place or people associated with drug use, they are capable of cuing drug-associated memories or feelings that motivate continued drug use or relapse,” concluded Dani.

The study has been published in the latest issue of the journal Neuron. (ANI)

Song birds have to deal with cover artists too

Washington, Sep 9 (ANI): Just like great singers among humans, birds too have to deal with cover artists who copy songs.

A new research has revealed that some bird species have evolved to sing the same tune as their rivals, in order to compete effectively.

Led by Dr. Joseph Tobias and Dr Nathalie Seddon from the Edward Grey Institute, University of Oxford, the research team analysed the calls and songs of two antbird species that were living side-by-side in the Amazon rainforest- the Peruvian warbling-antbird and the yellow-breasted warbling-antbird.

The study was aimed at investigating their similar songs, and, in particular, at testing the theory that the birds’ songs could become increasingly similar to enable effective communication between competing species.

The above notion has attracted controversy as many scientists have argued that convergence in territorial or mating signals results in needless confrontation or crossbreeding and the creation of hybrids.

“Biologists have long been fascinated by convergence in ecological traits as it offers tangible evidence of evolution and the forces of selection by which it operates, but until now there is no clear evidence that social competition between animal species can produce convergent signals. We examined this idea by analysing the structure and function of songs in two birds which we knew to be strong social competitors,” said Tobias.

The researchers studied the species in Peru and Bolivia at one site where they lived together, and two sites where they lived in isolation.

Firstly, they recorded three sets of signals-songs, calls, and plumage colour of both species (including a total of 504 songs from 150 individuals).

Later, they played them back to individuals of each species to test the significance of songs of both types.

The results showed that territorial songs of both species were extremely similar particularly where they lived together, such that territorial birds treated songs of both species as equally threatening.

In the meantime, they discovered that non-territorial signals like calls and plumage were highly divergent.

“In effect, the territorial songs of these birds are more or less interchangeable in design and function. Given that they last shared a common ancestor more than 3 million years ago, it is almost equivalent to humans and chimpanzees – which diverged around 5 million years ago – using the same language to settle disputes over resources” said Tobias.

“Our results provide the first compelling evidence that social interaction can cause convergent evolution in species competing for space and resources.

They also suggest that while competition drives convergence in territorial songs, this is offset by divergence in non-competitive signals such as plumage colour to promote species recognition and reduce the chance of interbreeding,” he added.

The study has been published in Evolution.(ANI)

Researchers make bacteria to produce useful proteins

Washington, Sep 7 (ANI): Researchers at the University of British Columbia have turned the bacterium Caulobacter crescentus into a protein production factory by adapting a single protein on its surface, thus making useful proteins that can act as vaccines and drugs.

C. crescentus is a harmless bacterium that has a single protein layer on its surface.

Led by Dr. John Smit, the researchers adapted the system that secretes this protein, which self-assembles into a structure called the “S-layer”, to secrete instead many proteins that are useful for vaccines and other therapeutic purposes.

In other words, by keeping the S-layer protein intact and genetically inserting new things inside it, they produce a very dense display of useful proteins on the cell surface.

The researchers are now hoping to use the entire bacterium in a therapeutic application.

Bacteria are commonly used in biotechnology to produce useful protein products.

If the bacteria secrete the protein rather than keep it contained within the cell, purification costs are greatly lowered.

The researchers have developed a commercially available kit based on this technology, which could be especially useful in developing countries as it might be used to manufacture HIV-blocking agents very cheaply and with little specialist expertise.

“This S-layer system is very efficient at producing and secreting proteins – we can make the bacterium into a protein pump, secreting over half of all the protein it makes as engineered S-layer protein,” said Smit.

He added: “Applications of S-layer display that we are currently developing include anti-cancer vaccines, an HIV infection blocker and agents to treat Crohn’s and colitis, and diarrhoea in malnourished populations”.

Smit presented the findings at the Society for General Microbiology’s meeting at Heriot-Watt University, Edinburgh. (ANI)

High-performance, low-cost green LEDs to brighten up the future

Washington, September 6 (ANI): A scientist is aiming to develop a high-performance, low-cost green LED (Light-emitting diode).

According to Christian Wetzel, professor of physics and the Wellfleet Professor of Future Chips at Rensselaer Polytechnic Institute (RPI), “Going green means different things to different people. For companies, going green means making a profit by selling equipment and services that allow one’s customers to be more efficient and reduce costs.”

“I’m doing both of those, but I’m also trying to make an LED that literally shines green light,” he said.

First discovered in the 1920s, LEDs are semiconductors that convert electricity into light.

When switched on, swarms of electrons pass through the semiconductor material and fall from an area with surplus electrons into an area with a shortage of electrons.

As they fall, the electrons jump to a lower orbital and release small amounts of energy. This energy is realized as photons – the most basic unit of light.

Unlike conventional light bulbs, LEDs produce almost no heat.

The color of light produced by LEDs depends on the type of semiconductor material it contains.

“We have high-performance red LEDs, we have high-performance blue LEDs, and if we paired them with a high-performance green LED we would be able to produce every color visible to the human eye – including true white,” said Wetzel.

“Every computer monitor and television produces its picture by using red, blue, and green. That means developing a high-performance green LED would likely lead to a new generation of high-performance, energy-efficient display devices,” he added.

“The problem, however, is that green LEDs are much more difficult to create than I, or anyone else, imagined,” he explained.

Simple preliminary attempts to create green LEDs, by merely adding more indium (In) to the gallium nitride (GaN) materials that composed blue LEDs, were unsuccessful.

The resulting green LEDs just weren’t strong or bright enough to stand toe-to-toe with red or blue.

Wetzel and his research group have been working to tweak precisely how to add more indium, and how to grow the structure more carefully into a device, with the goal of boosting the strength and light output of green LEDs.

“They’re endeavoring, he said, to close the green gap,” said Wetzel.

Once they overcome the challenge of developing efficient green LEDs, Wetzel envisions LED technology will quickly evolve from its current applications in signs and small displays and grow into a universally adopted, globally used replacement for traditional light bulbs and compact fluorescence tubes. (ANI)

Ancient Indus Valley script communicated language, determines computer modeling

Washington, September 2 (ANI): A team of mathematicians and scientists has rejected claims that the Indus Valley people were functionally illiterate, by employing computer modeling to prove that the Harappan script communicated language.

In 2004, perhaps out of befuddlement and frustration, a group of scholars declared that the ancient Indus Valley script marked only rudimentary pictograms and that the people during the Harappan period were functionally illiterate.

According to a report in the TIME, that hypothesis, which caused a minor uproar in the world of Indus Valley researchers, was recently rejected by a team of mathematicians and computer scientists assembled from institutions in the US and India.

They employed computer modeling to prove that the Harappan script communicated language, and has reinvigorated attempts to crack what is one of the lingering puzzles of ancient history.

The group examined hundreds of Harappan texts and tested their structure against other known languages using a computer program.

Every language, the scientists suggest, possesses what is known as “conditional entropy”: the degree of randomness in a given sequence.

In English, for example, the letter t can be found preceding a large variety of other letters, but instances of tx and tz are far more infrequent than th and ta.

“A written language comes about through this mix of built-in rules and flexible variables,” said Mayank Vahia, an astrophysicist at the Tata Institute for Fundamental Research in Mumbai who worked on the study.

Quantifying this principle through computer probability tests, the scientists determined that the Harappan script had a similar measure of conditional entropy to other writing systems, including English, Sanskrit and Sumerian.

If it mathematically looked and acted like writing, they concluded, then surely it is writing.

But this is just a first step. Vahia and his colleagues hope to piece together a solid grammar from the sea of impenetrable Indus signs.

Their August research paper charted the likelihood of certain characters appearing in parts of a text – for example, a fish sign appeared most frequently in the middle of a sequence and a U-shaped jar sign toward the end.

Bit by bit, the structure of the script is coming into view.

“We want to find the bedrock against which all further interpretation of the language should be checked,” said Vahia.

Down the road, he imagines he could write in “flawless Harappan” – even though he may have no idea what the assembled sequences would mean. (ANI)

Scientists create world’s smallest semiconductor laser

Washington, August 31 (ANI): Researchers at the University of California (UC), Berkeley, have created the world’s smallest semiconductor laser, capable of generating visible light in a space smaller than a single protein molecule, an invention that breaks new ground in the field of optics.

The UC Berkeley team not only successfully squeezed light into such a tight space, but found a novel way to keep that light energy from dissipating as it moved along, thereby achieving laser action.

While it is traditionally accepted that an electromagnetic wave – including laser light – cannot be focused beyond the size of half its wavelength, research teams around the world have found a way to compress light down to dozens of nanometers by binding it to the electrons that oscillate collectively at the surface of metals.

This interaction between light and oscillating electrons is known as surface plasmons.

Scientists have been racing to construct surface plasmon lasers that can sustain and utilize these tiny optical excitations.

However, the resistance inherent in metals causes these surface plasmons to dissipate almost immediately after being generated, posing a critical challenge to achieving the buildup of the electromagnetic field necessary for lasing.

Zhang and his research team took a novel approach to stem the loss of light energy by pairing a cadmium sulfide nanowire – 1,000 times thinner than a human hair – with a silver surface separated by an insulating gap of only 5 nanometers, the size of a single protein molecule.

In this structure, the gap region stores light within an area 20 times smaller than its wavelength.

Because light energy is largely stored in this tiny non-metallic gap, loss is significantly diminished.

With the loss finally under control through this unique “hybrid” design, the researchers could then work on amplifying the light.

Trapping and sustaining light in radically tight quarters creates such extreme conditions that the very interaction of light and matter is strongly altered, the study authors explained.

“This work shatters traditional notions of laser limits, and makes a major advance toward applications in the biomedical, communications and computing fields,” said Xiang Zhang, professor of mechanical engineering and director of UC Berkeley’s Nanoscale Science and Engineering Center.

The achievement helps enable the development of such innovations as nanolasers that can probe, manipulate and characterize DNA molecules; optics-based telecommunications many times faster than current technology; and optical computing in which light replaces electronic circuitry with a corresponding leap in speed and processing power.

Scientists hope to eventually shrink light down to the size of an electron’s wavelength, which is about a nanometer. (ANI)

Same neural networks in brain process familiar and newly learnt words

Washington, August 29 (ANI): A series of experiments conducted as part of the Academy of Finland’s Neuroscience Research Programme (NEURO) have shown that the brain uses the same neural networks to process both familiar and newly learnt words.

In one experiment, participants learnt the name and/or purpose of 150 ancient tools. They had never heard those words before.

Their brain function was measured by means of magnetoencelography during the naming of the tools, both before and after the learning period.

It was observed that their brains used the same neural networks to process both familiar and newly learned words.

Academy Professor Riitta Salmelin, HUT Low Temperature Laboratory, who is in charge of the research, revealed that the names of objects were processed in the left temporal and frontal lobe within half a second of showing the image of the tool to the subject.

“If the subject had only recently learned the name of the tool, the naming process induced an activation that was just as strong or stronger than the activation induced by the image of a familiar object,” the researcher said.

Salmelin added that the learning of the meaning of ancient tools did not cause corresponding clear differences in the function of the brain.

According to the researcher, it seems that the processing of meanings in the brain differs essentially from the processing of names.

On the other hand, said Salmelin, the performance results indicated that new definitions were learnt even faster than new names.

The research team are now working on a follow-up study to explore the retention of learned words.

“We are also conducting a separate series of experiments to find out how our brain learns phonetic structures and, on the other hand, how the brain learns to identify letter combinations that are typical of a certain language,” Salmelin said.

Another area of interest in the ongoing study is the role of grammar in language learning.

The researchers say that they will try to explore how the brain learns to use the vocabulary and grammatical structure of an experimental miniature language. (ANI)

Scientists uncover vulnerable enzyme that can be targeted to kill dangerous pathogens

Washington, August 28 (ANI): A collaborative study conducted by researchers from three institutions in the U.S. has shown that an enzyme, which is essential to many bacteria, can be targeted to kill dangerous pathogens.

Experts at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have also identified chemical compounds that can inhibit this enzyme, and suppress the growth of pathogenic bacteria.

Writing about their study in the journal Chemistry and Biology, the researchers say that their findings are essential to develop new broad-spectrum antibacterial agents to overcome multi-drug resistance.

Dr. Andrei Osterman, an associate professor in Burnham’s ioinformatics and Systems Biology program, targeted the acterial nicotinate mononucleotide adenylyltransferase (NadD), an essential enzyme for nicotinamide adenine dinculeotide (NAD) biosynthesis, which has many crucial functions in nearly all important pathogens.

The bacterial NadD differs significantly from the human enzyme.

“It’s clear that because of bacterial resistance, we need new, wide-spectrum antibiotics. This enzyme is indispensable in many pathogens, so finding ways to inhibit it could give us new options against infection,” said Dr. Osterman.

The research team used a structure-based approach to search for low-molecular-weight compounds that would selectively inhibit bacterial NadD, but not the human equivalent, by screening, in silico, more than a million compounds.

In their experiments, they tested the best predicted compounds against Escherichia coli and Bacillus anthracis (anthrax), which led them to a handful of versatile inhibitory chemotypes, which they explored in detail.

Using protein crystallography, a 3D structure of the enzyme in complex with one of the inhibitors was solved providing guidelines for further drug improvement.

“This is proof-of-concept that NadD is a good target to create antibacterial agents. This knowledge will be useful for both biodefense and public health. The next step is to find better inhibitors. We do not have a silver bullet yet, but we are certainly hitting a golden target,” said Dr Osterman.

The research was supported by a grant from the National Institute of Allergy and Infectious Diseases. (ANI)