South African officials withhold findings of Caster Semenya’s gender test

London, Sep. 19 (ANI): Even before South African star athlete Caster Semenya’s gender was questioned at the World Championships in Berlin, Athletics South Africa (ASA) had found out and withheld the fact that she had internal testes, an e-mail exchange has revealed.

According to the e-mail exchanges published in the Mail and Guardian newspaper, ASA officials were aware of the findings of a Pretoria clinic that Semenya had internal testes and produced abnormal amounts of testosterone for a woman, Times Online reports.

It was ASA’s chief medical officer and team doctor, Harold Adams, who had suggested the need carrying out the tests on Semenya, 18, because of her deep voice, muscular body and facial hair, which later became a subject of controversy in Berlin.

Another email exchange shows that Adams later suggested that the results to be kept confidential while the South African team was in Berlin.

“Thinking about the current confidential matter, I would suggest we make the following decisions. 1. We get a gynae opinion and take it to Berlin. 2. We do nothing and I will handle these issues if they come up in Berlin,” the report quoted from Dr Adams’ email to ASA President Leonard Chuene and General Manager Molatelo Malehopo, as saying.

Following the IAAF establishing that Semenya was a hermaphrodite, South African officials not only angrily denounced it, but also denied carrying out their own tests.

Taking matters a step further, South African Sports Minister Makhenkesi Stofile lost his temper at a press conference and threatened to start a “third world war” if Semenya was banned from international competition because of her gender.

Earlier, Semenya’s ex-coach Wilfred Daniels had said the ASA had duped Semenya into thinking the gender test carried out on her were routine drug tests. (ANI)

Tim Paine is heir-apparent to Haddin, says Harrison

Melbourne, Sep 18 (ANI): Tasmanian Cricket Association chairman Tony Harrison has said that Tim Paine’s match-winning one-day century for Australia against England should make all cricket followers aware of his class and potential.

“Wicketkeeper batsman Tim Paine’s first international one-day century scored against England overnight and his outstanding form behind the stumps have clearly stamped him as the heir-apparent Australian wicketkeeper,” Harrison said.

“Tim has easily fitted into international cricket and looks extremely comfortable in the Australian team,” he said.

Harrison said Paine was now clearly Australia’s second wicketkeeper behind Test incumbent Brad Haddin.

“But I am confident he can and will take the next step,” The Australian quoted Harrison, as saying.

Paine scored 111 runs giving Australia a 111-run victory over England in the penultimate match of their one-day series at Trent Bridge.

Australian selector David Boon today said that Paine was staking a claim for selection as Australia’s wicketkeeper for the domestic summer.

“It will be very important for him to continue to show this form and confidence through to the last game in England and then in the Champions Trophy,” Boon told ABC radio.

“Who knows? If he comes back to Australia and has a strong start to the domestic season his future is in his hands basically.” (ANI)

Will Sarabjeet be spared the gallows under Pak Govt.’s plans to commute death sentences?

Islamabad, Sep.17 (ANI): The Pakistan government is considering commuting death sentences, but such a step may not help the cause of Sarabjeet Singh, the Indian inmate who has been awarded a death sentence by a Lahore anti-terrorism court in October 1991.

Interior Advisor Rehman Malik said the government has sent a draft to the law division seeking legal opinion on the proposal to commute death sentences.

Rehman, however, said that even if the proposal is accepted there would be no mercy for terrorists.

“They (terrorists) will have to face the death penalty,” The Dawn quoted Malik, as saying.

According to an estimate there are 7000 death inmates in Pakistan at present.

Pakistan security agencies have maintained that Singh had admitted that he was sent to Pakistan to carry out serial bomb blasts in Lahore, Faislabad, and Kasur, and was trained by the Indian Army, and the Research and Analysis Wing (RAW).

Singh was awarded the death sentence by a Lahore anti-terrorism court in October 1991.

He challenged the verdict in the Supreme Court, however, the apex court quashed his appeal in September, 2005, saying that the review petition was not filed within the time period as mentioned in the law.

In March 2006, a two member Supreme Court bench dismissed Singh’s petition against his conviction in the Lahore’s Yakki Gate bomb blast in 1990.

Singh has been languishing in Pakistan jails for the last 28 years, as Pakistan has stonewalled release even on humanitarian grounds, despite continuous efforts by Indian diplomatic channels. (ANI)

India Air Force activates Nyoma airfield close to China border

New Delhi, Sep 18 (ANI): The Indian Air Force in a significant move today activated its Nyoma Advanced Landing Ground (ALG) to support the Army in carrying out operations in the inhospitable terrain.

An IAF AN-32 aircraft landed at Nyoma ALG, which is located at an altitude of 13,300 feet in Leh district of Jammu and Kashmir, at 6:25 a.m. today. It is located 23 kms from the Line of Actual Control. (LAC).

The successful landing of a fixed wing aircraft at Nyoma marks the culmination of joint effort by the IAF and Indian Army to enable the IAF to operate in the inhospitable terrain of Leh-Ladakh region in support of the Army.

The landing comes just fifteen months after an AN-32 landed at Daulat-Beg-Oldie (DBO), the highest airfield in the world situated at an altitude of 16,200 feet.

Group Captain SC Chafekar touched down on the Nyoma airstrip. Air Marshal NAK Browne, Air Officer Commanding-in-Chief, Western Air Command and Lieutenant General PC Bharadwaj, General Officer Commanding-in-Chief, Northern Command on board.

Though helicopters have been landing at this ALG, this is for the first time that a fixed wing aircraft has landed at the compact airstrip of Nyoma.

After deliberating on all aspects and carrying out aerial and ground inspection, it was concluded that Nyoma could be developed for fixed wing operations as well.

The Engineer Regiments of 14 Corps undertook the herculean task of developing the ALG to the standards required for fixed wing operations.

Joint development of Nyoma braving the extremely difficult working conditions and hostile weather is yet another step towards enhanced joint partnership between the two services.

Nyoma has been developed with an aim to connect the remote areas of Ladakh region to the mainland. This would also ensure movements in the area when the road traffic gets affected, during the harsh winters besides enabling improved communication network in the region. (ANI)

Stem cell transplantation may correct rare genetic disorder in kids

Washington, Sep 18 (ANI): Scripps Research Institute scientists have offered new hope for parents whose children suffer from the rare genetic disorder ‘cystinosis’ by showing through an experiment on mice that stem cell transplantation can successfully correct the defect.

“After meeting the children who suffer from this disease, like an 18-year-old who has already had three kidney transplants, and the families who are desperately searching for help, our team is committed to moving toward a cure for cystinosis, a lysosomal storage disorder. This study is an important step toward that goal,” said principal investigator Stephanie Cherqui.

In the study, the researchers used bone marrow stem cell transplantation to address symptoms of cystinosis in a mouse model.

The procedure virtually halted the cystine accumulation responsible for the disease, and the cascade of cell death that follows.

Cystine is a by-product of the break down of cellular components the body no longer needs in the cell’s “housekeeping” organelles, called lysosomes.

Normally, cystine is shunted out of cells, but in cystinosis a gene defect of the lysosomal cystine transporter causes it to build up, forming crystals that are especially damaging to the kidneys and eyes.

Cystinosis is a rare but devastating disease affecting children as young as six months, who begin to suffer renal dysfunction, which grows progressively worse with time. Other symptoms include diabetes, muscular disease, neurological dysfunction, and retinopathy.

The only available drug to treat cystinosis, cysteamine, while slowing the progression of kidney degradation, does not prevent it, and end-stage kidney failure is inevitable.

In the new study, the researchers found that transplanted bone marrow stem cells carrying the normal lysosomal cystine transporter gene abundantly engrafted into every tissue of the experimental mice.

This led to an average drop in cystine levels of about 80 percent in every organ.

Not only it prevented kidney dysfunction, there was less deposition of cystine crystals in the cornea, less bone demineralization, and an improvement in motor function.

“The results really surprised and encouraged us. Because the defect is present in every cell of the body, we did not expect a bone marrow stem cell transplant to be so widespread and effective,” says Cherqui.

Cherqui said that adult bone marrow stem cell therapy is particularly well suited as a potential treatment for cystinosis because these cells target all types of tissues.

In addition, stem cells reside in the bone marrow for the duration of a patient’s life, becoming active as needed, a particular benefit for a progressive disease like cystinosis.

The study has been published in the journal Blood. (ANI)

Facebook crosses 300m users mark, cites rapid growth in profits

London, September 16 (ANI): Facebook has announced that it has crossed a benchmark of 300 million active monthly users from across the world and also started raking in profits ahead of schedule.

Founder of the world’s largest social networking site Mark Zuckerberg said the company had not expected to begin reaping financial benefits until sometime next year.

“This is important to us because it sets Facebook up to be a strong independent service for the long term,” The BBC quoted Zuckerberg as saying in a blog post.

“We are succeeding at building Facebook in a sustainable way. We are just getting started on our goal of connecting everyone.

“We face a lot of fun and important challenges that require rethinking the current systems for enabling information flow across the web,” he added.

Mike Schroepfer, Facebook’s vice president of engineering, also said: “Passing these milestones to me means we can continue to fund our development and our innovation and be self sustaining as we grow this network.

“We think 300m is a just a step on the way to get as much of the entire world on the social network communicating with the friends and family and the people they want to communicate with.”

Nick O’Neill of AllFacebook.com added: “That Facebook is able to continue this growth and build a “cash flow positive” business is an impressive feat.

“If the company can cover the cost of scaling to 1 billion users and still manage to break even, there’s no doubt that the company will have a great opportunity to rake in billions.”

The news that the company had crossed the two benchmarks was made at TechCrunch 50 in San Francisco. (ANI)

Scientists develop ‘electronic nose’ that can sniff out toxins by changing colors

Washington, September 14 (ANI): A team of scientists has developed a sensor that works as an ‘electronic nose’ in sniffing out some known poisonous gases and toxins, simply by changing colors.

Support for the development and application of this electronic nose comes from the National Institute of Environmental Health Sciences, part of the National Institutes of Health.

Once fully developed, the sensor could be useful in detecting high exposures to toxic industrial chemicals that pose serious health risks in the workplace or through accidental exposure.

While physicists have radiation badges to protect them in the workplace, chemists and workers who handle chemicals do not have equivalent devices to monitor their exposure to potentially toxic chemicals.

The investigators hope to be able to market the wearable sensor within a few years.

“The project fits into the overall goal of a component of the GEI Exposure Biology Program that the NIEHS has the lead on, which is to develop technologies to monitor and better understand how environmental exposures affect disease risk,” said NIEHS Director Linda Birnbaum.

“This paper brings us one step closer to having a small wearable sensor that can detect multiple airborne toxins,” she added.

Kenneth S. Suslick, the M.T. Schmidt Professor of Chemistry at the University of Illinois at Urbana-Champaign, and his colleagues have created what they refer to as an optoelectronic nose, an artificial nose for the detection of toxic industrial chemicals (TICs) that is simple, fast, inexpensive, and works by visualizing colors.

“We have a disposable 36-dye sensor array that changes colors when exposed to different chemicals. The pattern of the color change is a unique molecular fingerprint for any toxic gas and also tells us its concentration,” said Suslick.

“By comparing that pattern to a library of color fingerprints, we can identify and quantify the TICs in a matter of seconds,” he added.

The power of this sensor to identify so many volatile toxins stems from the increased range of interactions that are used to discriminate the response of the array.

To test the application of their color sensor array, the researchers chose 19 representative examples of toxic industrial chemicals.

Chemicals such as ammonia, chlorine, nitric acid and sulfur dioxide at concentrations known to be immediately dangerous to life or health were included.

The arrays were exposed to the chemicals for two minutes.

Most of the chemicals were identified from the array color change in a number of seconds and almost 90 percent of them were detected within two minutes. (ANI)

New test to detect tainted milk

Washington, Sept 13 (ANI): Researchers have developed a simple test that would help detect tainted milk within few hours.

Amer AbuGhazaleh, from Southern Illinois University Carbondale’s College of Agricultural Sciences, and Salam Ibrahim, a food microbiologist from North Carolina Agricultural and Technical State University, have shown that the combination of certain bacteria and a common purple dye can reveal the presence of toxins in milk in just a few hours.

“To date, detecting the presence of toxins or pesticides has only been possible by sending samples to a laboratory and waiting a few days for the results,” said AbuGhazaleh.

“An important step toward improving the safety of our dairy supply would be the development of an effective, simple and rapid test that would allow farmers or processors to detect the presence of foreign substances,” the expert added.

During the study, the scientists decided to focus on the bacteria that ferment lactose (milk’s sugars), producing lactic acid.

“For one thing, these bacteria already exist in milk, so if you add some, you’re not doing anything strange,” said AbuGhazaleh.

“Second, they produce a change over time (the lactic acid) that we could monitor. If we didn’t see the change, we would know something was wrong,” the expert said.

They began in 2008 with a few bacterial strains they already had and cyanide, also readily available. Experiments showed not only that the toxin could slow or stop lactic acid production but that this effect increased with the toxic load. Further, the effect appeared in less than four hours.

They then added purple dye to milk samples containing both toxins and bacteria and to samples containing only bacteria.

After eight hours, dye in the non-toxic milk turned yellow, indicating the presence of increased lactic acid, while dye in the toxin-laden milk retained its original purple.

“This kind of colour test could be performed by farmers themselves,” AbuGhazleh said.

“They could add the bacteria and the dye to a sample, leave it alone for a little while and then come back to see if there is any change in the color. If there isn’t, there are problems with the milk,” he added. (ANI)

Deployment of women constables cheers farmers in Punjab’s border villages

Rorawala (India-Pakistan Border), Sep.11 (ANI): As women constables of the Border Security Force (BSF) were deployed at the India-Pakistan International Border on Friday, a wave of cheer overwhelmed the villagers here.

Male farmers expressed their delight over the development, saying the presence of women security personnel would encourage their womenfolk to join them in the fields near the border.

The fencing of the 553-kilometer-long border since the 1990s; has created a feeling of reluctance among rural women to cross the border gates to work in fields or to deliver meals.

Most of them were hesitant in undergoing a frisking of their bodies, a security provision to check against the smuggling of unwanted material from across the border.

In such conditions, farmers were compelled to hire outside help on daily wages.

Hailing the step, farmers in the border area said their financial burden would be reduced with their women stepping in to assist them.

They also said that the deployment of women constables would enable them to access cheap labour.

Raj, a woman labourer, said: “I am very happy since it was difficult to get work in the village. We can now go to the fields beyond the fencing and earn much for our families.”

Balwinder Kaur of Rorawala village said that her family owned about ten acres of land beyond the fencing and some times it was difficult to cultivate it due to the shortage of labourers.

Now, with the presence of female security personnel, she said that she and other females of the family were ready to help in the cultivation process beyond the fenced wiring.

Joginder Singh, a farmer, said that he was now looking forward to the fresh meals brought to him by the womenfolk of his family.

Mohammad Aquil, DIG (Border Range) BSF, said the deployment of the lady BSF constables would be done in the state of Punjab within two months.

A senior BSF official said about 178 girls would be posted at the international border dividing India and Pakistan. At a later stage, 60 of these women constables would be deployed along the India-Bangladesh border

These women are aged between 19-25 and are fully trained in the use of weapons, patrolling and other combat tasks, they will be assigned non-combat duties along the fenced border.

Gurbir Kaur, a woman constable, said that the (soldiers)’ uniform always fascinated her. She said that being in uniform was a dream come true.

Raman Preet Kaur, another lady constable, said that apart from frisking, she was also trained to handle a security-related crisis at the border.

These women passed out of the BSF academy in Kharkan near the town of Hoshiarpur on July 25 this year. By Ravinder Singh Robin (ANI)

India, Nepal agree to review Air Service Agreement

New Delhi, Sep 11 (ANI): India and Nepal signed here a Memorandum of Understanding (MoU) for review of Air Service Agreement (ASA) and a technical accord.

As per the understanding reached between the delegation from the two countries, the weekly seat capacity has been increased to 30,000 from the existing 6,000. This step can safely be expected to give a whole new boost to tourism as well as trade between the two countries.

Three new points have been granted to Nepal, namely Dehra Dun, Gorakhpur and Bagdogra and for India, Pokhara, Lumbini, Biratnagar, Nepalgunj, Janakpur, Dhangadi and Bhairahawa.

However, within their overall capacity entitlements, the designated airlines of Nepal shall be entitled to operate not exceeding 10,000 seats per week to/from Mumbai and Bangalore each and not exceeding 15,000 seats per week to/from Delhi. This restriction will become null and void from January 1, 2011.

Regarding the revised route schedule, the Nepali delegation stated that barring Kathmandu, there is no other airport in Nepal which is suitable for operation of international flights.

The designated airlines of each party shall be entitled to operate any number of all-cargo services between each other’s territory with any type of aircraft with full 3rd, 4th and 5th freedom traffic rights. Such all-cargo services may also be operated under co-operative marketing arrangements such as code sharing blocked space.

The delegations took note of the Technical Co-operation Agreement signed between the Airports Authority of India and the Civil Aviation Authority of Nepal. Both sides agreed to take further action for implementation of this Agreement.

The Indian side reiterated its request that permission for the deployment of sky marshals on the flights operated by the designated airlines of India to/from Nepal may be expedited.

The Nepal side took note of the request and informed that the matter had already been referred to the appropriate authority of the Government of Nepal. The Nepal side will pursue the matter. This Memorandum of Understanding shall super cede all previous arrangements to the extent applicable and shall come into force with immediate effect.

The Indian delegation was led by M. Madhavan Nambiar, Secretary, Ministry of Civil Aviation and the Nepal side was led by Nagendra Prasad Ghimire, Secretary, Ministry of Tourism and Civil Aviation. (ANI)

Abandoned by children, inmates of an old-age perform ‘Shraadh’ in Bhopal

Bhopal, Sep.10 (ANI): Abandoned by their own children, many elderly people at an old-age home in Bhopal, performed ‘Shraadh’ for themselves during the ongoing ‘Pitrapaksha’.

As per Hindu tradition, one’s children or family members perform the Shraadh, the ritual of remembering the deceased.

These elderly inmates took the unusual step, as they realised there was no one in their families to perform this ritual.

“They (children) will not do the salvation ritual for us after our death. We are doing it for ourselves. If today they are treating us in this manner, we don’t know what they will do after our death. What can we say?… There is no one to see us. There is no one to listen to our plight… We will die like this here one day,” said Murari Lal Saxena, inmate of Anand Dham old-age-home.

By performing their own ‘shraadh’ rituals, the elderly said they were preparing for their next life.

Parmanad Agrawal, whose family members have died, said in this age and time he couldn’t trust his relatives to do ‘Shraadh’ for him.

“I’m doing my own salvation ritual. So that I don’t suffer in my next life,” said Parmanad Agrawal, an inmate of Anand Dham, the old age home.

Meanwhile, the in-charge of the old-age home Madhuri Mishra said that the inmates did the rituals out of a sense of compulsion.

“All elderly members were worried and in a sad mood. They said since their children have left them in an old age home then why not do their own post-death ritual even if they were still alive. This will leave no burden on their sons after their death. The elderly performed the rituals in the early morning,” said Madhuri Mishra, In-charge, Anand Dham Old-Age-Home.

Hindus believe in reincarnation, or in the cycle of birth. They believe that the body changes with every birth but the soul remains the same.

According to the Hindu philosophy, this birth and death cycle can be broken and the soul can be liberated by performing “Pind Daan” (rituals for dead).

During ‘Pitrapaksha’, children perform the ceremony and pray that the souls of their ancestors should rest in peace. By Ram Chand Sahu(ANI)

Taller people are happier than shorter ones

London, Sept 9 (ANI): Taller people are much happier with their lives than shorter peers, says a new study by U.S. academics.

The research published in science journal Elsevier’s Economics and Human Biology claimed people of greater height ‘live better lives’ on average, as they are better equipped to deal with life’s problems compared to their vertically challenged counterparts and they possess more of a positive outlook.

To reach the conclusion, scientists interviewed around 454,065 American adults, asking them all to detail their height, their emotions and where they saw themselves on an “imaginary life ladder.”

From analyses, boffins found that taller people reported a range of positive emotions such as enjoyment and happiness than shorter people in the survey, reports The Daily Express.

Men who reported that their lives were the ‘worst possible’ were more than eight tenths of an inch (2cm) shorter than the average man.

Women who saw themselves ‘on the bottom step’ were shorter than the average woman by half an inch (1.3cm).

However, not everything was rosy for leggier participants.

The taller you are, the more likely you are to experience stress and anger, whilst tall women have a tendency to over-worry, the study found. (ANI)

Marriage breakdown helped Hilary Swank find new love

Washington, September 9 (ANI): Actress Hilary Swank has accorded finding love again to the breakdown of her marriage.

The ‘Million Dollar Baby’ star, who announced her split with Chad Lowe in 2006, had turned to her agent John Campisi for comfort.

The Oscar-winner revealed their working relationship came to an end when they started dating.

“There was no spark. What’s interesting is, there was never anything. It wasn’t until we were well into the dissipation of our respective relationships,” Contactmusic quoted her as telling Britain’s Hello magazine.

“Going through something so difficult at the same time, we became very good friends. We became closer and closer.

“It was so unexpected. We both recognised that if we were going to take the relationship to the next step, we could no longer work together,” she added. (ANI)

Over-expressed protein may make non-invasive breast cancer invasive

Washington, Sep 9 (ANI): An over-expressed protein can convert active but non-invasive breast cancer into a different cell type, and thereby turn it into invasive breast cancer, according to scientists at The University of Texas M. D. Anderson Cancer Center.

The researchers say that overexpression of the protein 14-3-3? (zeta) launches a molecular cascade that removes bonds that tie the pre-malignant cells together, and hold them in place, converting them from stationary epithelial cells to highly mobile mesenchymal-like cells.

This epithelial-to-mesenchymal transition (EMT) is recognized as a crucial step in metastasis, the spread of cancer to distant organs that causes 90 percent of all cancer deaths.

“We have discovered a key molecular mechanism for the deadly transition of non-invasive breast cancer into invasive disease,” said senior author Dr. Dihua Yu.

The researchers have shown that the zeta protein teams up with the oncoprotein ErbB2, also known as HER2, in a two-hit process to convert normal mammary cells to invasive cancer cells.

The findings of the study also provided a biomarker in zeta to identify high-risk patients for more aggressive treatment before their noninvasive breast cancer converts to invasive disease.

The researchers also got new therapeutic targets among the components of the molecular pathway launched by zeta.

According to Yu, some drugs already aim at these targets.

In addition, they found a solution to a puzzling mystery about how a subset of non-invasive breast cancer with excessive presence of an ErbB2/HER2 develops into invasive breast cancer.

Earlier, the researchers showed that zeta is over-expressed in many other cancer types, like lung, liver, uterine, stomach cancers.

“Our findings might have broader implications relating to the mechanism of invasion and metastasis in other types of cancer,” Yu said.

The researchers said that it would be very challenging to target zeta by drugs because it also regulates other important proteins in normal cellular processes.

The study has been published in the journal Cancer Cell. (ANI)

Hilary Swank says there was no ‘spark’ when she first met beau John Campisi

Washington, Sep 8 (ANI): Hilary Swank has said that there was no initial “spark” between her and new beau John Campisi because both of them were nursing a broken heart at the time, and their romance was completely “unexpected”.

Hilary was in the process of divorcing Chad Lowe when she started working with John in May 2006.

“There was no spark. What’s interesting is, there was never anything. It wasn’t until we were well into the dissipation of our respective relationships. Going through something so difficult at the same time, we became very good friends. We became closer and closer,” Contactmusic quoted Swank as telling Britain’s Hello! Magazine.

“It was so unexpected. We both recognised that if we were going to take the relationship to the next step, we could no longer work together,” she added.

While the 35-year-old star has no intention of marrying John, 41, in the near future, she hopes to start a family with him one day.

She even enjoys spending time with his son Sam, from a previous relationship.

“Sam’s a sweetheart. I most definitely want children. It’s something I’d like to do someday. And when the timing is right I’ll hopefully know it,” she said. (ANI)

Fat-rich junk food may alter genes linked with type II diabetes

London, September 8 (ANI): A team of scientists in Sweden have warned that gorging too much on fat-rich junk food may cause drastic changes to a gene that helps muscle cells burn fat.

Juleen Zierath, of the Karolinska Institute in Stockholm, says that her team’s findings may help improve the scientific understanding of how type II diabetes develops in adulthood.

“Somehow, the environment plays on the genes we have,” says the lead researcher, adding that her study provides new clues to how this happens.

She says that it may be possible that the altered cells become so engorged with unburnt fat that they become “diabetic”, and stop accepting signals from the hormone insulin, which normally triggers the absorption of glucose from the bloodstream.

However, proving that components in the diet can permanently alter genes is itself a breakthrough, as it provides the first evidence that the food people eat may change the function of their DNA, a process scientifically known as “epigenetics”.

During the study, the researchers observed that the DNA itself remained unchanged, except for a masking process called methylation that can permanently mothball a gene by capping individual chemical units or bases.

Before the researchers undertook this research, they had already found in a previous study that muscle cells from people with type II diabetes showed such telltale epigenetic alterations to their DNA, particularly in the PGC-1 gene, which orchestrates metabolic programmes critical to the burning of fat in mitochondria, the chambers in cells that generate energy.

In the current study, the researchers achieved the most significant result when they exposed the healthy muscle cells to the edible fatty acid, palmitic acid.

The team found that the PGC-1 gene became methylated, just as it is in people with diabetes.

“The palmitic acid essentially switches off the gene,” New Scientist magazine quoted Zierath as saying.

She says that the fact that fat produces such an effect is highly significant, as it means that over-consumption of junk food may cause the same response.

“It suggests that if you eat a fat-rich diet, something in that – either the fat itself or the build up of metabolites – triggers the methylation of genes. The net effect is that it switches off the gene,” says Zierath.

The team’s analyses also reveal that the shutdown of PGC-1 led to inactivation of other genes vital for burning or transporting fat.

Zierath says that her team’s next step will be to find out how different diets affect the methylation status of PGC-1 and other genes vital for burning energy, hoping that their efforts will lead to the discovery of a potential mechanism by which type II diabetes develops.

A research article on her study has been published in the journal Cell Metabolism. (ANI)

Indians, Chinese credited with helping make Wellington an international city

Wellington, Sep. 5 (ANI): New Zealand-born Indians and Chinese living in Wellington have been credited with helping the capital in its quest to become an international city.

According to an Asia NZ Foundation report by Auckland University’s Wardlow Friesen, India and China have close links with the city, as one-third of Indians and Chinese living in Wellington are New Zealand-born.

“The report shows how far the city has come in terms of diversity of its population, which was something people had generally embraced and celebrated.

“Its conclusions reflect a very important step on Wellington’s journey to becoming a truly international city,” The Dominion Post quoted Wellington Mayor Kerry Prendergast, as saying.

The study points out that a small Chinatown emerged in Wellington in the 19th century as Chinese moved north after the gold rush, whereas Indian settlement was more sporadic and gradual.

Thanks to diplomatic posts and international universities, Wellington is continuously attracting Asian population, which is predicted to double from 37,000 to 61,000 by 2012, it adds.

Asians living in Wellington consider the city to be “cosmopolitan”, “quiet”, and its people friendly.

“I never feel like a stranger in this city. Actually now it feels like my home,” said Sarjon Warde, originally from Iraq.

There are 121 Asian restaurants in Wellington, including 30 Indian, 29 Chinese and 15 Thai restaurants. (ANI)

Army, IGNOU sign MoU to give soldiers’ second career option

New Delhi, Sep. 4 (ANI): A Memorandum of Understanding has been signed between Indian Army and Indira Gandhi National Open University to meet the twin objectives of empowering soldiers educationally and providing an opportunity for a second career option.

The MoU was signed by Lieutenant General Mukesh Sabharwal Adjutant General and IGNOU Vice Chancellor Professor VN Rajasekharan Pillai in the presence of Army Chief General Deepak Kapoor at South Block today.

The MoU seeks to confer educational certification to soldiers of the Indian Army, within the parameters laid down by IGNOU for Community Colleges, recognizing the ‘in-service’ training done by them; within the broad frame work set out by IGNOU.

IGNOU will register Regimental Training Centres/Human Resource Development Centres of the Indian Army and Army Schools of Instructions as ‘Community Colleges’.

The Army-IGNOU Community Colleges will function as autonomous bodies conducting examinations and their courses as before.

Credits from such approved courses will be transferred to the programme and will count towards the desired credits to be earned for an associate degree.

Certain credits are to be earned for a Graduation Degree which would be from approved elective courses offered by IGNOU or the Army to be undertaken after grant of an Associate Degree.

Approval of these courses with credit ratings would be accorded and reviewed by the ‘Army-IGNOU Academic Committee’ at regular intervals.

With the signing of the MOU with IGNOU leading towards award of academic diploma/associate degree and Graduation Degree to soldiers, a major step forward has been taken to empower the soldier to live a life of dignity and confidence after he leaves the service for a second career.

The project has been named as ‘Gyan Deep’ signifying knowledge. (ANI)

PPP has not given any ‘guarantee’ regarding Musharraf indemnity: Kaira

Islamabad, Sep.4 (ANI): Pakistan Information and Broadcasting Minister Qamar Zaman Kaira has rebutted reports regarding Pakistan People’s Party (PPP) giving assurance not to prosecute former President General Pervez Musharraf on high treason charges.

Kaira said the PPP has not given any ‘guarantee’ to any country regarding clemency to Musharraf.

“Though friendly countries generally give advice on various matters but it is not binding on the government,” Kaira said.

In an interview with The Nation, he categorically rejected media reports that Musharraf’s step down was pre-planned and a part of a ‘secret’ arrangement.

“PPP had expelled Musharraf from Aiwan-e-Sadr with the support of masses,” he stressed.

When asked about Interior Advisor, Rehman Malik’s visit to Saudi Arabia, just before Musharraf’s meeting with king Abdullah bin Abdul Aziz, Kaira said it was a routine affair and it had nothing to do with the Musharraf issue.

Kaira also denied presence of US Blackwater on Pakistani soil, saying Islamabad would never allow any private security agency to operate inside country’s territory.

“Some personnel of private security agencies of the US after taking clearance by the government are protecting the NATO trucks which transport supplies from Port Qasim to Afghanistan and nothing else,” he said.

“As the US is leading war against terror therefore its facilities and staff are more prone to terror attacks than other countries therefore they need more security to protect themselves,” he added. (ANI)