Young age at first drink can turn under-15s into alcoholics

Washington, Sept 19 (ANI): Drinking at young age may affect genes linked to alcoholism and make youngsters vulnerable to severe problems, says a new study.

The study led by Dr Arpana Agrawal, from Washington University School of Medicine in St. Louis, revealed that the younger an individual was at first drink, the greater the risk for alcohol dependence and the more prominent the role played by genetic factors.

“There seemed to be a greater genetic influence in those who took their first full drink at a younger age,” said Agrawal.

“That’s very consistent with what has been predicted in the literature and in the classification of types of alcohol dependence, but we present a unique test of the hypothesis,” she added.

During the study, the researchers studied 6,257 adult twins from Australia and measured the extent to which age at first drink changed the role of heritable influences on symptoms of alcohol dependence.

The study showed that when twins started drinking early, genetic factors contributed greatly to risk for alcohol dependence, at rates as high as 90 percent in the youngest drinkers.

The team also found that those who were 15 or younger when they started drinking tended to have a greater genetic risk for alcohol dependence.

However, some who were 16 or older before they took their first drink later became alcohol dependent, but their dependence was related more to environmental factors.

“Something about starting to drink at an early age puts young people at risk for later problems associated with drinking,” Agrawal says.

“We continue to investigate the mechanisms, but encouraging youth to delay their drinking debut may help.

“Some early-onset drinkers do not develop alcohol problems and some late-onset drinkers do – we are working on why that is the case, but it is important to note that this is one risk factor among many and does not determine whether a person will, or will not, develop alcohol dependence.

“But age at first drink is a well-known risk factor, and there have been two main hypotheses about why:

One has been that common genetic and environmental factors contribute both to the risk for alcohol dependence and to the likelihood a person will be younger when consuming their first drink,” she added.

The study will be published Alcoholism: Clinical and Experimental Research. (ANI)

US Army Nurse reveals ‘humane’ side of Saddam Hussein

Washington, Sep. 11 (ANI): Saddam Hussein might be remembered as a brutal international criminal by the rest of the world; but to retired U.S. Army Nurse Robert Ellis, who spent more time with the dictator than any other American, he was a patient with a humane side.

Ellis worked as the senior American medical advisor at Baghdad’s Camp Cropper, where Hussein was held for eight months until his execution in December 2006, Fox News reports.

During this period, Hussein who went by the code name “Victor” grew close to his caregiver, who was known to him by the code name “Alice.”

The report quoted Ellis as saying that when he told Hussein that he had to return to St. Louis to see his dying brother, Hussein hugged him and said: “I will be your brother.”

Ellis’ new book, “Caring for Victor,” is a record of his time with the ruthless tyrant.

For Ellis, the mission caused serious internal conflict.

“I was always conflicted throughout the whole mission. My job was to keep these people alive and healthy so they could be interrogated,” he said.

Ellis says that by remaining “non-judgmental,” he was able to see another side of a human who was considered to be a brutal killer.

“By me spending time with him, I got to see his other side, a side that you don’t hear about. They play by a different set of rules over there,” he added. (ANI)

Sleep can reduce mistakes in memory

Washington, Sept 11 (ANI): Here’s a pointer for students flubbing multiple-choice tests: Sleep can reduce mistakes in memory, says a new study.

The first-of-its-kind study led by a cognitive neuroscientist at Michigan State University, appears in the September issue of the journal Learning and Memory.

Kimberly Fenn, principal investigator and MSU assistant professor of psychology, said: “It’s easy to muddle things in your mind.”

“This research suggests that after sleep you’re better able to tease apart the incorrect aspect of that memory,” the expert added.

To reach the conclusion, Fenn and colleagues from the University of Chicago and Washington University in St. Louis studied the presence of false memory in groups of college students. While previous research has shown that sleep improves memory, this study is the first to address errors in memory, she said.

Study participants were exposed to lists of words and then, 12 hours later, exposed to individual words and asked to identify which words they had seen or heard in the earlier session. One group of students was trained in the morning (10 a.m.) and tested after the course of a normal sleepless day (10 p.m.), while another group was trained at night and tested 12 hours later in the morning, after at least six hours of sleep.

Three experiments were conducted, using different stimuli. In each, the students who had slept had fewer problems with false memory – choosing fewer incorrect words. (ANI)

Teen pregnancy ‘a symptom, not cause, of psychological stress’

Washington, July 28 (ANI): Teenage mothers suffer a lot of psychological stress in their lives, however, a new research has shown that the distress comes before the pregnancy, not because of it.

“Psychological distress does not appear to be caused by teen childbearing, nor does it cause teen childbearing, except apparently among girls from poor households,” said Stefanie Mollborn, Ph.D., an assistant professor of sociology at the Institute of Behavioral Science of the University of Colorado at Boulder.

The study has been published in the September issue of the Journal of Health and Social Behavior.

To reach the conclusion, researchers used data from two large long-term U.S. surveys that followed thousands of teen girls and women.

Participants responded to items on symptoms associated with depression, such as how often they found things that did not usually bother them to be bothersome, how easily they could shake off feeling blue or whether they had trouble concentrating.

The researchers did not use the term “depression,” which is a clinical diagnosis.

Only the combination of poverty and existing distress was a good predictor of teen pregnancy.

“Psychologically distressed girls are at risk for teen childbearing and vice versa, even if the two things usually do not cause each other,” Mollborn said.

“This could help educators and clinicians identify at-risk adolescents,” Mollborn added.

Looking for symptoms of depression or distress should be part of normal health screening for all teenagers, said Diane Merritt, M.D., director of Pediatric and Adolescent Gynecology at the Washington University School of Medicine in St. Louis.

“Talking to teenagers about their sexuality and responsible behavior is key,” she said.
ne of the best ways to prevent teen pregnancy is for teens to have long-term goals and good self-esteem, Merritt added. (ANI)

Anna Kournikova spotted with diamond ring on engagement finger

Melbourne, July 07 (ANI): Anna Kournikova has been spotted with a huge diamond ring on her engagement finger.

The hot Tennis star, who has long been linked to singer Enrique Iglesias, showed off her ring when she came to watch World Team Tennis on Monday night, the Daily Telegraph reports.

However, when she was asked if the ring meant she was committed, she simply replied: “I thought you were the good press.”

The Russian bombshell became conscious and hid her hand behind her back.

Kournikova was scheduled to play for the St. Louis Aces but will miss the season because of a wrist injury.

She still participated in a kid’s clinic, signed autographs and cheered on her teammates. (ANI)

Kids’ brains are organised differently than adults’

Washington, May 16 (ANI): Children often confront their parents over some or the other issue. Perhaps scientists have now found out why kids show such behaviour.

Researchers at Washington University and Oregon Health and Science University suggest that children’s brains are organised differently than adults’.

However, the same study also provides parents with a rejoinder: hile the overarching organization scheme differs, one of the most important core principals of adult brain organization is present in the brains of children as young as 7.

“Regardless of how tempting it might be to assume otherwise, a normal child’s brain is not inherently disorganized or chaotic. It’s differently organized but at least as capable as an adult brain,” says senior author Dr. Steven E. Petersen, the James McDonnell Professor of Cognitive Neuroscience at Washington University School of Medicine in St. Louis.

Scientists previously revealed four brain networks with varying responsibilities in the adult brain. Two of those networks appear to be co-captains in charge of most voluntary brain function. The networks typically involve tight links between several brain regions that are physically distant from each other.

In the new study, this is where the organizational contrast arises. The researchers observed that instead of having networks made of brain regions that are distant from each other but functionally linked, most of the tightest connections in a child’s brain are between brain regions that are physically close to each other.

Lead researchers Dr. Damien A. Fair, a former Washington University graduate student who is now associated with Oregon Health and Science University, and Alexander L. Cohen, a current Washington University graduate student, directed analysis of data from 210 subjects ranging from 7 to 31 years old.

“We took a group of the youngest subjects, analysed their results, then dropped data from the youngest and added data from the next-oldest and redid the analysis until we had worked our way through all subjects. The result was a detailed movie of how the organizational transition from a child’s brain to an adult’s brain takes place. It clearly shows a switch from localized networks based on physical proximity to long-distance networks centred on functionality,” Fair says.

Scientists already knew that children had many fewer long-distance links among brain regions than adults, but when they looked more closely, they found there were enough of these links and nodes with multiple connections to establish small-world organization.

The researchers set the lower limit for study subjects at 7 years of age because the brain is approximately 95 percent of its adult size at this age, but they are currently examining ways to adapt the study to the changing physical geography of younger brains.

They have also begun looking at the same phenomena in subjects with brain injuries and developmental disorders.

The study has been published online in PLoS Computational Biology. (ANI)

Kids’ brains are organised differently than adults’

Washington, May 16 (ANI): Children often confront their parents over some or the other issue. Perhaps scientists have now found out why kids show such behaviour.

Researchers at Washington University and Oregon Health and Science University suggest that children’s brains are organised differently than adults’.

However, the same study also provides parents with a rejoinder: hile the overarching organization scheme differs, one of the most important core principals of adult brain organization is present in the brains of children as young as 7.

“Regardless of how tempting it might be to assume otherwise, a normal child’s brain is not inherently disorganized or chaotic. It’s differently organized but at least as capable as an adult brain,” says senior author Dr. Steven E. Petersen, the James McDonnell Professor of Cognitive Neuroscience at Washington University School of Medicine in St. Louis.

Scientists previously revealed four brain networks with varying responsibilities in the adult brain. Two of those networks appear to be co-captains in charge of most voluntary brain function. The networks typically involve tight links between several brain regions that are physically distant from each other.

In the new study, this is where the organizational contrast arises. The researchers observed that instead of having networks made of brain regions that are distant from each other but functionally linked, most of the tightest connections in a child’s brain are between brain regions that are physically close to each other.

Lead researchers Dr. Damien A. Fair, a former Washington University graduate student who is now associated with Oregon Health and Science University, and Alexander L. Cohen, a current Washington University graduate student, directed analysis of data from 210 subjects ranging from 7 to 31 years old.

“We took a group of the youngest subjects, analysed their results, then dropped data from the youngest and added data from the next-oldest and redid the analysis until we had worked our way through all subjects. The result was a detailed movie of how the organizational transition from a child’s brain to an adult’s brain takes place. It clearly shows a switch from localized networks based on physical proximity to long-distance networks centred on functionality,” Fair says.

Scientists already knew that children had many fewer long-distance links among brain regions than adults, but when they looked more closely, they found there were enough of these links and nodes with multiple connections to establish small-world organization.

The researchers set the lower limit for study subjects at 7 years of age because the brain is approximately 95 percent of its adult size at this age, but they are currently examining ways to adapt the study to the changing physical geography of younger brains.

They have also begun looking at the same phenomena in subjects with brain injuries and developmental disorders.

The study has been published online in PLoS Computational Biology. (ANI)

Coaching can reduce hospitalizations of asthmatic kids

Washington, May 06 (ANI): A new study has shown that working with an asthma coach helps to significantly reduce hospitalizations of low-income, African-American children with asthma.

For the study, researchers at Washington University School of Medicine in St. Louis and the University of North Carolina at Chapel Hill worked with nearly 200 parents of children between 2-8 years old on Medicaid who had been hospitalized for asthma at St. Louis Children’s Hospital.

Kids were randomly assigned to an asthma coach or to usual care following discharge from the hospital, which included asthma education, an asthma management plan and a suggested follow-up appointment with the child’s pediatrician within one week of discharge.

“Compliance with asthma care can often be a challenge,” said Robert C. Strunk, M.D., a Washington University asthma specialist at St. Louis Children’s Hospital.

“The asthma coach provided support for parents dealing with the unrelenting demands of their child’s illness,” he added.

During two years, the coach was available to parents, 35 of the 96 patients (36.5 percent) in the coaching group were hospitalized at least once, compared with 55 of the 93 patients (59 percent) in the usual-care group.

Edwin B. Fisher, Ph.D., professor of health behavior and health education at the University of North Carolina at Chapel Hill, co-author of the paper and global director of Peers for Progress, a program to promote peer support in chronic disease, said: “Beyond the good news it provides for asthma care, the asthma coach sets an important model for treating a variety of chronic diseases in children and adults.”

“These kinds of programs help people put into practice in their daily lives the plans they agree to in the doctor’s office. That’s going to be an increasingly important part of health care as more people have problems like asthma and diabetes,” Fisher added.

The study was published in the March 2009 issue of Archives of Paediatrics and Adolescent Medicine. (ANI)

Endoscopic surgery can effectively relieve sinusitis symptoms

Washington, May 1 (ANI): A new study claims that endoscopic sinus surgery can significantly relieve symptoms of chronic rhinosinusitis – inflammation of the sinus cavities.

The research team, led by a Georgetown physician, conducted the first large-scale analysis of surgical outcomes from the procedure.

In the May issue of Otolaryngology Head Neck Surgery, researchers found that symptoms usually associated with the chronic condition, including nasal obstruction, facial pain, postnasal discharge, headaches, and impaired smell, all substantially improved after endoscopic sinus surgery.

“This kind of surgery is indeed beneficial to patients when standard medical treatment doesn’t resolve the condition,” says the study’s lead investigator, Alexander C. Chester, MD, a physician and clinical professor at Georgetown University Medical Center. Two other physicians from St. Louis University School of Medicine collaborated in the study.

Endoscopic sinus surgery is an extremely common procedure – about 200,000 procedures are performed each year – yet this is the first meta-analysis of symptom relief following the surgery, Chester says. It was conducted by examining 21 different published studies, which included 2,070 patients, analyzing improvement for each symptom.

“Reports of relative symptom relief vary across studies, so it was important to pool the study results. We wanted to know not only if symptoms improve overall, but if they improve to a similar degree, and if these benefits last,” says Chester.

“Our findings offer reassurance that, with minor exceptions, individual symptoms usually improve substantially and similarly following surgery,” Chester, an internist, said.

The researchers assessed symptom relief using two different measures. The most precise is called “effect size” where any effect greater than .8 is considered a large effect. The researchers found that with a 1.73effect size, nasal obstruction improved the most, followed by postnasal discharge (1.19), facial pain (1.13), headache relief (.98) and improvement in smell (.97). A second way of measuring symptoms, which is less accurate but more commonly used, compares the percent of improvement after surgery compared to before surgery. They found the following percentage improvements: 61 percent in facial pain, 59 percent in nasal obstruction, 53 percent in headache, 49 percent in smell, and 47 percent in postnasal discharge.

They also found that improvements do not decrease over time, as some smaller studies had suggested. (ANI)

Under Obama, three in five Americans see improvement in race relations

New York, Apr.28 (ANI): The latest New York Times/ CBS News poll claims that the Barack Obama presidency is seeking to alter the public perception of race relations in the United States.

According to the poll, three out of five Americans now say race relations are generally good, and the percentage of blacks who say so has doubled since last July.

The poll found Black Americans remain among the president’s staunchest supporters — 70 percent of black respondents now say the country is headed in the right direction, compared with 34 percent of whites.

The poll found broad support for Obama’s approach on a variety of issues, including one of the most contentious: whether Congress should investigate the harsh interrogation tactics authorized by George W. Bush.

Sixty-two percent of Americans share Obama’s view that hearings are unnecessary.

Americans seem to have high hopes for the president — 72 percent said they were optimistic about the next four years and by and large, Americans expect him to make significant progress in health care, energy and immigration policy, issues central to his ambitious domestic agenda.

But this optimism is tempered by a feeling of resignation about two of the most difficult challenges he faces: reviving the economy and ending United States military involvement in Iraq.

Most Americans say Obama has begun to make progress on both fronts, but many do not expect either the recession or the war to be over by the end of his term.

Obama’s 68 percent job approval rating is higher than that of any recent president at the 100-day mark.

But while Americans clearly have faith in Obama, the poll revealed something of a disconnect between what the public thinks the president has already accomplished and what it expects him to achieve.

Obama will mark his 100th day in office on Wednesday with a trip to St. Louis and a prime time news conference, where aides say he will make the case that he has made “a down payment” on fixing the nation’s biggest problems.

The nationwide telephone survey was conducted Wednesday through Sunday with 973 adults. For purposes of analysis, blacks were over sampled in this poll, for a total of 212, and then weighted back to their proper proportion in the poll, based on the census. The margin of sampling error is plus or minus three percentage points for all people, and plus or minus seven points for blacks. (ANI)

Keri Hilson Joins Keyshia Cole and The Dream on the 20-City ‘A Different Me’ Tour

Keri Hilson Joins Keyshia Cole and The Dream on the 20-City ‘A Different Me’
Tour

The Tour Kicks off May 13th in Cincinnati, Ohio

SANTA MONICA, Calif., April 20 /PRNewswire/ — Singer/Songwriter Keri Hilson
will join Keyshia Cole and The Dream on the A Different Me tour which will
kick off on May 13th in Cincinnati, Ohio. Riding on the success as a guest
artist on Lil Wayne’s “I Am Music Tour,” Hilson has been given another
opportunity to engage fans with an exciting stage performance during the
20-city tour.

Hilson’s debut album In A Perfect World recently debuted at #1 on Billboard’s
R and B/Hip Hop Chart. Her current single “Knock You Down,” featuring Kanye West
and Ne-Yo, is steadily climbing the charts, and the video landed today at the
#1 spot on BET’s 106 and Park.

Cole and Hilson collaborated on Hilson’s third single “Get Your Money Up,”
which is also featured on the new album.

Stay connected to Keri Hilson by visiting http://www.kerihilsonmusic.com/.

A DIFFERENT ME TOUR DATES
DATE CITY VENUE

Wednesday, May 13 Cincinnati Aronoff Center

Thursday, May 14 Milwaukee Riverside Theatre

Friday, May 15 Chicago Chicago Theatre

Saturday, May 16 Detroit Fox Theatre

Thursday, May 21 Atlanta Fox Theatre

Friday, May 22 Greensboro Special Events Arena

Saturday, May 23 Atlantic City Mark Etess Arena Taj Mahal

Sunday, May 24 NYC WAMU @ MSG

Thursday, May 28 DC Constitution Hall

Saturday, May 30 Norfolk Ntelos Pavilion

Sunday, May 31 Columbia, SC Township Auditorium

Tuesday, June 2 Newark NJPAC

Friday, June 5 Mashantucket, CT MGM Foxwoods

Saturday, June 6 Baltimore Pier Six Pavilion

Tuesday, June 9 Nashville Ryman Auditorium

Thursday, June 11 St. Louis Fox Theatre

Saturday, June 13 Dallas Nokia Live

Sunday, June 14 Houston Reliant Arena

Thursday, June 18 Oakland Paramount Theater

Saturday, June 20 LA Nokia

SOURCE Interscope Records

Yvette Gayle, +1-310-865-6278, fax, +1-310-865-7903, yvette.gayle@umusic.com,
or Fairley McCaskill, +1-310-865-9634, fax, +1-310-865-7903,
fairley.mccaskill@umusic.com, both for Interscope Records

Soon, smartphones to provide ultrasound imaging

Washington, April 22 (ANI): Scientists in the U.S. hope to bring the minimalist approach to medical care with the use of a medical imaging device that fits in the palm of the hand.

William D. Richard, Ph.D., Washington University in St. Louis associate professor of computer science and engineering, and David Zar, research associate in computer science and engineering, have made commercial USB ultrasound probes compatible with Microsoft Windows mobile-based smartphones.

In order to make commercial USB ultrasound probes work with smartphones, the researchers had to optimize every aspect of probe design and operation, from power consumption and data transfer rate to image formation algorithms.

As a result, it is now possible to build smartphone-compatible USB ultrasound probes for imaging the kidney, liver, bladder and eyes, endocavity probes for prostate and uterine screenings and biopsies, and vascular probes for imaging veins and arteries for starting IVs and central lines.

“You can carry around a probe and cell phone and image on the fly now,” said Richard.

“Imagine having these smartphones in ambulances and emergency rooms. On a larger scale, this kind of cell phone is a complete computer that runs Windows. It could become the essential computer of the Developing World, where trained medical personnel are scarce, but most of the population, as much as 90 percent, have access to a cell phone tower,” he added.

Zar said: “Twenty-first century medicine is defined by medical imaging. Yet 70 percent of the world’s population has no access to medical imaging. It’s hard to take an MRI or CT scanner to a rural community without power.” (ANI)

Final game of Cubs-Cards series rained off

CHICAGO (Reuters) – Sunday’s game between the Chicago Cubs and St Louis Cardinals was postponed because of poor weather and will be played as part of a day-night double-header on July 12.

The final game in a series of four was called off before a pitch could be thrown following steady rain in cold conditions and a dismal forecast for the evening.

“The weather’s terrible and, looking at the radar, there’s no end in sight,” Cubs manager Lou Piniella told Chicago’s website (www.chicago.cubs.mlb.com).

“Early in the season with the cold weather and wet fields, you can get some injuries. That’s my biggest concern. No question, our bullpen could use a break.”

Both teams were scheduled to have Monday off but were keen not to play then given another poor weather forecast followed by the start of a 20-game stretch on Tuesday.

The Cubs led the four-game series 2-1, Aramis Ramirez having hit a game-winning two-run homer in the 11th inning on Saturday for the home team.

(Writing by Mark Lamport-Stokes in Los Angeles; Editing by John O’Brien; To query or comment on this story email sportsfeedback@thomsonreuters.com)

King Penguin Properties, LLC Adds to Planned Distressed Real Estate Team

NEW YORK, April 15 /PRNewswire/ — King Penguin Properties, LLC (KPP) is
pleased to announce the addition of David Riehl to its distressed real estate
team. Mr. Riehl joins a distressed real estate fund that will focus on
acquiring assets in the five boroughs of New York City.

Mr. Riehl most recently worked as a distressed debt analyst for Cedarcrest
Fund, LP in New York where he analyzed and purchased troubled bank loans from
US banks, The FDIC and The National Credit Union Administration. He has
performed extensive due diligence on distressed commercial properties located
in the New York metro area and in other major cities across the United States.
He has experience with the overall start-up process of a private investment
fund including legal formation, fundraising, asset acquisition, financial
reporting and fund management.

Mr. Riehl is a member of the National Association of Bankruptcy Trustees and
The International Debt Buyers Association. He has experience in dealing with
workout attorneys to solve creditor disputes and has been both a secured and
unsecured creditor in a number of bankruptcy cases. He has initiated legal
proceedings in roughly 75 cases and has significant experience with the
foreclosure process. In addition to his workout experience, Mr. Riehl managed
a portfolio of REO properties in upstate New York acquired through distressed
debt investments and oversaw their liquidation for a significant return on
investment.

Mr. Riehl started his career at Merrill Lynch in Washington, D.C. where he
worked on a team of financial advisors. Mr. Riehl holds a Bachelor of Arts
from Webster University, St. Louis and a Graduate Certificate in Business from
Columbia University in the City of New York.

About King Penguin Properties, LLC:

Founded in 1998 and based in New York City, King Penguin Properties owns and
manages multi-family, residential, office, and commercial property in North
America and Europe. For more information please refer to their website at
www.kpp.us.com

SOURCE King Penguin Properties, LLC

Norah Lawlor, Lawlor Media Group, +1-212-967-6900, Norah@lawlormediagroup.com

Sharks, Bruins top field for Stanley Cup Playoffs

NEW YORK (Reuters) – The San Jose Sharks and the Boston Bruins will be the top conference seedings when the Stanley Cup playoffs begin on Wednesday.

The league-leading Sharks will host the eighth-seeded Anaheim Ducks on Thursday in one of four Western Conference opening series, the NHL said on Sunday.

Defending Stanley Cup champions Detroit (2) will open at home against Columbus (7) on Thursday, Vancouver (3) host St Louis (6) on Wednesday and Chicago (4) will face Calgary (5) a day later.

The best-of-seven matchups shift to the home of the lower seeds after two games.

In the East, conference leader Boston will host Montreal (8) on Thursday, while second-placed Washington will begin its series against New York Rangers (7) at home on Wednesday.

New Jersey (3) will meet Carolina (6) at Newark on Wednesday, while Pittsburgh (4) host Philadelphia (5) on the same day.

St Louis’s 1-0 victory at Colorado on Sunday, the final day of the regular season, determined the final Western pairings.

In the East, Philadelphia’s 4-3 loss to the New York Rangers on Sunday gave Pittsburgh fourth place and the home-ice advantage in their series.

(Reporting by Gene Cherry in Raleigh, North Carolina; Editing by John O’Brien)

‘Meetings on the Move’ spark workplace productivity, fights obesity

Washington, Apr 12 (ANI): For those wondering how to improve their employees’ productivity, ‘Meetings on Move’ concept might do the needful.

Researchers from Washington University in St. Louis have revealed that implementing the ‘Meetings on Move’ concept would significantly increase productivity and improve employees’ health by getting them up from their desks and on the move.

“Forty percent of the population are absolute couch potatoes,” said Dr Debra Haire-Joshu, and professor of social work at Washington University.

“That’s almost a learned behaviour. You learn to sit at school; you learn to sit at work.

“What ‘Meetings on the Move’ (MOTM) really does is get us active like we used to be when we were kids. We can learn then to bring activity back into our daily life, just like we learned to take it out.

“On a personal level, I struggle with a chronic condition – migraines, and research shows that getting away from a computer and adding extra physical activity can help chronic conditions like that,” she added.

The researchers said that MOTM could improve productivity by reenergizing employees by getting their blood pumping.

Ideas or problems can look very different once an individual steps out of the office.

It can also lower stress and help improve chronic conditions such as diabetes or migraines. (ANI)

The Obamas will go the full distance to get their favourite pizzas!

Washington, April 11 (ANI): U.S. President Barack Obama and First Lady Michelle Obama had a St. Louis chef flown all the way to Washington, D.C., to make pizzas for them in the White House’s kitchen.

Chris Sommers, who runs a pizza place in St. Louis called Pi, flew to the nation’s capital Thursday to make 20 pizzas for the Obama family and staff.

“It’s surreal, it’s a huge honour,” People magazine quoted Sommers, 33, as saying.

Obama first tried Sommers’ San Francisco-style pies while campaigning in Missouri last fall.

Sommers wanted to deliver a few frozen pies to the President after the election, but was unable to do so due to security reasons.

Finally, Obama’s closest aide Reggie Love arranged to have the chef bring 20 pounds of dough and three gallons of sauce at Sommers’s expense to the White House kitchen and cook there on Friday.

“It will be casual lunch,” says Sommers.

Helping him will be his girlfriend Anne Schuermann, 24, and Pi chef Ryan Mangialardo, 27.

“Hopefully we’ll have a chance to say hello to the President,” Sommers said. (ANI)

New test can help assess efficacy of Alzheimer’s drugs

Washington, Apr 10 (ANI): Researchers at Washington University School of Medicine in St. Louis have developed a new test that can assess whether an Alzheimer’s drug could really reduce the production of amyloid beta (A-beta)- one of the possible underlying causes of Alzheimer’s disease in humans.

With the test, called stable isotope-linked kinetics (SILK), the researchers showed that an Alzheimer’s drug given to healthy volunteers reduced A-beta production

The test could speed up the development of new treatments for the disease.

In the clinical trials by Eli Lilly and Company, the scientists are studying the drug candidate, LY450139, which is also known as semagacestat.

Ongoing clinical trials are studying the effect that semagacestat may have on cognitive function and biochemical and brain imaging biomarkers in patients with Alzheimer’s disease.

The researchers said that they wanted to see if SILK could detect the drug’s impact on A-beta synthesis in healthy volunteers.

“Bringing an Alzheimer’s disease drug into clinical trials from tests in animal models has always been challenging. We haven’t had a way to quickly and accurately assess a drug’s effects, and that meant there always had to be some degree of educated guesswork when it came to setting the optimal dosage for humans. SILK may help to eliminate much of that guesswork,” said study director Randall Bateman.

The researchers are currently using SILK to know if increased A-beta production, reduced clearance or a combination of the two lead to the A-beta buildup in the brain- a process believed to trigger Alzheimer’s disease.

Until SILK, there has not been a way to directly measure the production or clearance of A-beta.

Scientists have assessed the efficacy of potential new Alzheimer’s drug candidates by monitoring the cognitive functions of patients with the disease for extended periods of time, which require large, lengthy and expensive studies.

In the new study, the scientists reported a dose-dependent drop in A-beta production, and measured an 84 percent reduction in A-beta production with the highest study drug dose.

The SILK procedure takes 36 hours, but provides scientists a more detailed assessment of amyloid beta production and clearance levels than they can obtain through conventional methods.

“You could use a spinal tap to look directly at the amount of A-beta present in the cerebrospinal fluid, but we’ve shown that natural processes cause A-beta levels to change dynamically. Such changes make it more difficult to assess the effects of a drug in that fashion,” said Bateman.

The results have been published in Annals of Neurology. (ANI)

Sienna Miller in trouble for calling Pittsburgh “S-sburgh”

New York, Apr 9 (ANI): Hollywood actress Sienna Miller recently got into trouble while filming ‘The Mysteries of Pittsburgh’, when she tried to sound rhyming and called Pittsburgh “S-sburgh”.

The journalist interviewing Miller picked up her fault, and blew the matter out of proportion.

“It was a stupid joke because it rhymes. In the hands of a responsible journalist, humor and sarcasm will be translated appropriately,” the New York Daily News quoted Miller as saying.

“It was not meant as disrespectful in any way. In England, we have great rhyming slang, and everyone spends their day rhyming. But for all the trouble that comment caused, there were many people who were supportive,” she added.

However, co-actor Peter Sarsgaard defended Miller, as he stated that her words were unnecessarily made the subject of controversy.

“If I said that, no one would’ve cared. But a pretty British girl says it, and everyone is ready to pounce, I’ve said crap like that. I’m from St. Louis. You know what I’ve said about St. Louis?!” Peter said.

“Nooo! All wonderful things. You can like a place and dis it at the same time. Take NYC. There’s garbage in the streets. What other city does that?” Peter added. (ANI)

Heartburn pills of no help against asthma

London, Apr 9 (ANI): Heartburn medications are often prescribed to people with poorly controlled asthma, however, the treatment has been found ineffective in reducing asthmatic symptoms, say researchers.

The study led by the American Lung Association’s Asthma Clinical Research Centres has shown that heartburn medications do not help control asthma symptoms prescribed to those without significant heartburn.

The researchers found that participants who took esomeprazole (Nexium) had as many asthma episodes as participants who were given an inactive pill, or placebo.

“This study goes against the idea that mild or silent acid reflux contributes to uncontrolled asthma,” New England Medical Journal quoted Dr Mario Castro, a Washington University pulmonary specialist at Barnes-Jewish Hospital who led the study in St. Louis as saying.

“It establishes that heartburn medications are not indicated for adults with uncontrolled asthma when they have mild or no symptoms of acid reflux,” he added.

However, Castro said that the prescription heartburn medication is still indicated for those with severe heartburn and poorly controlled asthma because it might improve asthma control in some of these patients.

During the study, the researchers examined 412 patients who had poorly controlled asthma despite being treated with inhaled corticosteroids

However, they had either no or very mild acid reflux symptoms. Each participant was randomly assigned to receive either 80 milligrams of esomeprazole or a placebo daily.

In both the groups, episodes of poor asthma control occurred with similar frequency.

“Despite using four-times the typical dose of the heartburn medication, we achieved no improvement in asthma symptoms, control or exacerbation rates,” said Castro. (ANI)