Plotters of deadly Afghan attacks arrested: official

(Reuters) – Afghanistan’s intelligence department has detained four Taliban insurgents behind a series of deadly attacks against foreign targets in the capital, a spokesman for the agency said on Saturday.

The National Department for Security (NDS) also arrested another Taliban group which planned to stage attacks in Kabul in coming days, Saeed Ansari told reporters.

The first group was involved in five suicide attacks against foreigners in the city, including on the Indian embassy last year and another in February on a guest house used by Indian nationals. Scores of people, many of them Afghans, were killed.

The attacks were planned from Pakistan, where the Taliban have sanctuary, Ansari said.

“This group either managed to flee or went into hiding, but the vigilant officials of the NDS, with the help of people, managed to arrest them,” he said.

The second group consisted of six insurgents who carried out attacks against Afghan and foreign forces on a highway south of Kabul and planned further raids, including suicide bombings. Two of those held were clerics at local mosques in Kabul province.

NDS officials also seized around 450 kgs (1,000 pounds) of explosive materials during a raid against the group which was living in house on the outskirts of Kabul.

Removed from power in a U.S.-led invasion in 2001, the Taliban have made a comeback in recent years, despite the presence of nearly 150,000 foreign troops.

(Reporting by Sayed Salahuddin; Editing by David Fox)

Plotters of deadly Afghan attacks arrested – official

KABUL, July 10 (Reuters) – Afghanistan’s intelligence department has detained four Taliban insurgents behind a series of deadly attacks against foreign targets in the capital, a spokesman for the agency said on Saturday.

The National Department for Security (NDS) also arrested another Taliban group which planned to stage attacks in Kabul in coming days, Saeed Ansari told reporters.

The first group was involved in five suicide attacks against foreigners in the city, including on the Indian embassy last year and another in February on a guest house used by Indian nationals. Scores of people, many of them Afghans, were killed.

The attacks were planned from Pakistan, where the Taliban have sanctuary, Ansari said.

“This group either managed to flee or went into hiding, but the vigilant officials of the NDS, with the help of people, managed to arrest them,” he said.

The second group consisted of six insurgents who carried out attacks against Afghan and foreign forces on a highway south of Kabul and planned further raids, including suicide bombings. Two of those held were clerics at local mosques in Kabul province.

NDS officials also seized around 450 kgs (1,000 pounds) of explosive materials during a raid against the group which was living in house on the outskirts of Kabul.

Removed from power in a U.S.-led invasion in 2001, the Taliban have made a comeback in recent years, despite the presence of nearly 150,000 foreign troops.

(Reporting by Sayed Salahuddin; Editing by David Fox) (For more Reuters coverage of Afghanistan and Pakistan, see: here) (sayed.salahuddin@thomsonreuters.com; Kabul newsroom: +93 799 335 285)) (If you have a query or comment about this story, send an e-mail to news.feedback.asia@thomsonreuters.com)

Bradley expects Howard to be fit for Slovenia

(Reuters) – United States goalkeeper Tim Howard will have a rib injury evaluated later on Saturday but coach Bob Bradley expects him to play against Slovenia in their second Group C match.

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Howard suffered the injury when England striker Emile Heskey slid into him during the first half of the 1-1 draw in Rustenburg on Saturday but carried on after receiving treatment.

“At this point, there is no answer,” Bradley told reporters on Sunday when asked if Howard was doubtful for Friday’s match in Johannesburg.

“When you see the way Timmy handled himself after the collision, you’d certainly expect he will be on the field again.”

“He’ll be evaluated later today and then a decision will be made whether he will need further tests. Obviously he was sore, he did a great job of taking a tough hit, staying in it and playing it really well. We will assess it and figure out how to go on from there.”

The States have Marcus Hahnemann and Brad Guzan available as back-up.

Bradley said that after a tough encounter with England, he expected Friday’s opponent’s Slovenia to offer another style.

“I think it will be a different kind of game, obviously we will watch them but they are a hard working team, well organized and they have an ability to sometimes sit back a little and still catch you on the counter.

“Overall, the pure speed and physicality of Saturday’s game is on the very high end and the Slovenia game, in some ways, might be a little more of a chess match,” he said.

(Writing by Simon Evans; Editing by Jon Bramley)

Sodas, processed foods can accelerate signs of aging

Washington, Apr 27 (ANI): High levels of phosphate in sodas and processed foods can accelerate the aging process in mice and contribute to age-associated complications such as chronic kidney disease, claims a new study.

The study has been published in the FASEB Journal.

“Humans need a healthy diet and keeping the balance of phosphate in the diet may be important for a healthy life and longevity,” said M. Shawkat Razzaque, M.D., Ph.D., from the Department of Medicine, Infection and Immunity at the Harvard School of Dental Medicine. “Avoid phosphate toxicity and enjoy a healthy life.”

To reach the conclusion, Razzaque and colleague examined the effects of high phosphate levels in three groups of mice. The first group of mice was missing a gene (klotho), which when absent, causes mice to have toxic levels of phosphate in their bodies. These mice lived 8 to 15 weeks.

The second group of mice was missing the klotho gene and a second gene (NaPi2a), which when absent at the same time, substantially lowered the amount of phosphate in their bodies. These mice lived to 20 weeks. The third group of mice was like the second group (missing both the klotho and NaPi2a genes), except they were fed a high-phosphate diet. All of these mice died by 15 weeks, like those in the first group. This suggests that phosphate has toxic effects in mice, and may have a similar effect in other mammals, including humans.

“Soda is the caffeine delivery vehicle of choice for millions of people worldwide, but comes with phosphorous as a passenger” said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal. “This research suggests that our phosphorous balance influences the aging process, so don”t tip it.” (ANI)

Reading Franz Kafka’s book can make you smarter

Washington, Sept 16 (ANI): Reading a book written by Franz Kafka or watching a film by director David Lynch can enhance your learning power, suggest researchers.

Psychologists at UC Santa Barbara and the University of British Columbia revealed that exposure to the surrealism in, say, Kafka’s “The Country Doctor” or Lynch’s “Blue Velvet” enhances the cognitive mechanisms that oversee implicit learning functions.

“The idea is that when you’re exposed to a meaning threat-something that fundamentally does not make sense-your brain is going to respond by looking for some other kind of structure within your environment,” said Travis Proulx, a postdoctoral researcher at UCSB and co-author of the article.

“And, it turns out, that structure can be completely unrelated to the meaning threat,” Proulx added.uring the study, Proulx and Steven J. Heine, a professor of psychology at the University of British Columbia asked that participants to read an abridged and slightly edited version of Kafka’s “The Country Doctor,” which involves a nonsensical-and in some ways disturbing-series of events.

And second group read a different version of the same short story, one that had been rewritten so that the plot and literary elements made sense.

The subjects were then put through an artificial-grammar learning task in which they were exposed to hidden patterns in letter strings.

They were asked to copy the individual letter strings and then to put a mark next to those that followed a similar pattern.

“People who read the nonsensical story checked off more letter strings-clearly they were motivated to find structure,” said Proulx.

“But what’s more important is that they were actually more accurate than those who read the more normal version of the story. They really did learn the pattern better than the other participants did.

“People feel uncomfortable when their expected associations are violated, and that creates an unconscious desire to make sense of their surroundings.

“That feeling of discomfort may come from a surreal story, or from contemplating their own contradictory behaviors, but either way, people want to get rid of it. So they’re motivated to learn new patterns,” the expert added.

The findings appear in journal Psychological Science. (ANI)

Chronic alcohol disrupts body’s biological clock

Washington, Sept 1 (ANI): Chronic alcohol consumption can adversely affect body’s biological clock’s ability to synchronize daily activities to light, according to a new study on hamsters.

It continues to affect the body’s clock (circadian rhythm), even days after the drinking ends.

The researchers from Kent State University and the University of Tennessee have shown that alcohol consumption affects the master clock, located in the suprachiasmatic nucleus (SCN) section of the brain.

This clock controls the circadian cycle, a roughly 24-hour cycle, which regulates sleeping and waking, as well as the timing of a variety of other physiological functions, such as hormonal secretions, appetite, digestion, activity levels and body temperature.

Disruption of the clock dramatically increases the risks of developing cancer, heart disease, and depression, among other health problems.

In the new study, the researchers used hamsters to find out how alcohol affects circadian rhythms. The control group received water only. A second group received water containing 10pct alcohol and the third group received water containing 20pct alcohol.

The hamsters that drank alcohol had the hardest time shifting their rhythms after exposure to the dim light.

The more alcohol they drank, the harder it was to adjust.

Exposure to dim light caused the water-only hamsters to wake up 72 minutes earlier than they normally would. The 10pct alcohol group woke up 30 minutes earlier and the 20pct alcohol group woke up only 18 minutes earlier.

The hamsters that consumed alcohol had fewer bouts of activity that lasted longer than the water-consuming controls.

Chronic drinking continues to affect the biological clock even after withdrawal from alcohol.

The researchers aim to apply the research to people, who also show circadian disruptions from drinking.

It suggests that people who drink alcohol, particularly late into the night, may not respond to important light cues to keep their biological clocks in synch with daylight over the next 24 hours. Even low levels of alcohol may impair the response to light cues.

After the first 24 hours, the circadian cycle continues to be affected, even without further consumption of alcohol.

The findings appear in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. (ANI)

Acupuncture, exercise may help women with polycystic ovary syndrome

Washington, Aug 21 (ANI): Acupuncture and exercise can bring relief to women with polycystic ovary syndrome (PCOS), according to a new study.

Nearly 10pct of women of reproductive age suffer from PCOS. The syndrome expresses itself as a large number of small immature cysts on the ovaries that cause a disturbance in the production of hormones and an increase in the secretion of the male sex hormone.

Many women with the condition do not ovulate normally, and the syndrome may lead to infertility.

“We do not know for certain what causes the condition, despite it being so common. We have seen that women with the syndrome often have high activity in that part of the nervous system that we cannot consciously control, known as the ‘sympathetic nervous system,’” said lead researcher Elisabet Stener-Victorin, Sahlgrenska Academy, University of Gothenburg, Sweden.

“We believe that this may be an important underlying factor in the syndrome,” she added.

During the study, one group of women with polycystic ovary syndrome received a specific type of acupuncture called “electro-acupuncture” for four months.

In this type of acupuncture, the needles are stimulated with a weak low-frequency electric current, similar to that developed during muscular work.

A second group of women were provided with heart rate monitors and instructed to exercise at least three times a week.

The study showed that activity in the sympathetic nervous system was lower in the women who received acupuncture and in those who took regular exercise than it was in the control group.

The acupuncture treatment brought further benefits.

“Those who received acupuncture found that their menstruation became more normal,” she said.

“We could also see that their levels of testosterone became significantly lower, and this is an important observation, since elevated testosterone levels are closely connected with the increased activity in the sympathetic nervous system of women”, she added.

The study appears in American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. (ANI)

Grapefruit derivative ‘prevents obesity’

Washington, July 14 (ANI): A new study on mice, conducted by University of Western Ontario researchers, has shown that grapefruit contains a substance that’s a natural fat fighter.

Derived from citrus fruit, particularly grapefruit, the substance has shown it can reduce weight gain and fatty particles in the body, Murray Huff of UWO’s Robarts Research Institute said.

The substance, a flavonoid – a bioactive molecule – called naringenin, shows promise as an inhibitor of conditions associated with type 2 diabetes and cardiovascular disease, he said.

In the study, one group of mice was fed a high-fat diet to induce the symptoms of metabolic syndrome. A second group was fed the exact same diet and treated with naringenin.

Naringenin corrected the elevations in triglyceride and cholesterol, prevented the development of insulin resistance and completely normalized glucose metabolism.

The researchers found it worked by genetically reprogramming the liver to burn up excess fat, rather than store it.

“Furthermore, the marked obesity that develops in these mice was completely prevented by naringenin,” said Huff.

“What was unique about the study was that the effects were independent of caloric intake, meaning the mice ate exactly the same amount of food and the same amount of fat. There was no suppression of appetite or decreased food intake, which are often the basis of strategies to reduce weight gain and its metabolic consequences,” Huff added.

This study investigated naringenin’s preventative properties, but Huff is also investigating whether it can treat obesity and other existing metabolic problems.

The findings are published online in the journal Diabetes. (ANI)

Clever dogs find food by sniffing other dogs’ breath

London, July 8 (ANI): Dogs can find food by sniffing the snouts of fellow canines, finds a new study.

“They’re scavengers,” New Scientist magazine quoted Clive Wynne, a psychologist at the University of Florida in Gainesville, as saying.

“It would seem to be advantageous for them to pay attention to where another dog finds a titbit and go after it,” she added.

During the study, Marianne Heberlein at the Institute of Zoology in Zurich, Switzerland, left 13 dogs to search for food behind one of four barriers.

As the dogs had been shown where the treat was beforehand, they always went to the same place.

However, Heberlein took away the treat from some of dogs, and they found nothing to eat.

Then both groups of dogs were made to interact with 11 dogs from a second group, none of which knew where the treats were.

The researchers noted that sometimes dogs would sniff each other’s nose.

Each of the dogs from the second group was then allowed to search for food behind the barriers.

The researchers revealed that where the first pooch found food, the second dog tended to visit that corner first- especially if the dog had caught a whiff of the other’s breath.

Heberlein said that that showed that the second dog based its search on whether or not it smelled food on the breath of the first dog. (ANI)

New recommendations for drivers with Implanted cardioverter defibrillators

Washington, June 22 (ANI): A team of twelve experts have released a consensus statement with recommendations for drivers with Implantable Cardioverter Defibrillator (ICD).

ICD patients have an ongoing risk of sudden incapacitation that may cause harm to others while driving a car, and thus driving restrictions are imposed making these recommendations an important guideline for such patients.

And, recently, a consensus statement with recommendations for drivers with ICD’s was presented at a press conference at the Europace 2009 meeting, in Berlin, Germany.

Experts from the European Heart Rhythm Association (EHRA), the Council on Cardiovascular Nursing and Allied Professions in ESC (CCNAP) and the Section Cardiac Rehabilitation of the European Association of Cardiovascular Prevention and Rehabilitation, reviewed the literature, assessed the risk, and issued the consensus statement.

“Driving restrictions vary across different countries in Europe. We hope the document may serve as an instrument for European and National regulatory authorities to formulate uniform driving regulations,” said Johan Vijgen, chairperson of the task force.

He added: “Driving restrictions are perceived as difficult for patients and their family and have an immediate consequence for their lifestyle. In addition to the psychological and societal impact, the driving ban may also pose a considerable impact on employment and education and thereby economic status.”

The document presents recommendations for private driving (group 1) and professional driving (group 2).

While the first group includes drivers of ordinary motorcycles, cars, and other small vehicles with or without a trailer, the second group includes drivers of vehicles over 3.5 metric tonnes or passenger carrying vehicles exceeding eight seats excluding the driver.

Since the introduction of the ICD in the early 1980s, multiple trials have demonstrated the efficacy of ICDs for the prevention of sudden arrhythmic death, which resulted in a significant increase in the number of implants.

Many patients are currently implanted for primary prevention (treatment of patients at risk for life-threatening arrhythmias who have never had sustained ventricular arrhythmias). The risk for sudden incapacitation is lower in these patients.

Thus, driving restriction should be less strict for these patients, than for patients implanted for secondary prevention (those who have survived a life-threatening arrhythmia).

“Patients and their families should receive adequate discharge education and standardized information on driving recommendations. This should result in a better adherence to the recommendations. It should be emphasized that the risk is mainly a consequence of the underlying condition and not of the presence of the ICD,” said Vijgen.

The consensus statement has been published in Europace, the official journal of the European Heart Rhythm Association. (ANI)

Trauma prior to pregnancy affects offspring’s behaviour

Washington, May 13 (ANI): Trauma experienced by a mother before pregnancy will influence her offspring’s behaviour, according to a study.

The study was conducted on rats at the University of Haifa.

“The findings show that trauma from a mother’s past, which does not directly impact her pregnancy, will affect her offspring’s emotional and social behaviour. We should consider whether such effects occur in humans too,” said Prof. Micah Leshem, who carried out the study.

Earlier studies have researched trauma during pregnancy, this is the first study to investigate trauma prior to conception.

Rats were used in the investigation as they have found to behave socially in a similar way to humans.

Researchers examined three groups of rats: one group was put through a series of stress-inducing activities two weeks before mating, allowing the female time to recover before becoming pregnant; the second group was similarly treated over the course of a week immediately prior to mating; and the third, control group, were not given any form of stress.

Once the offspring of the rats had matured and were over 60 days old, their social and emotional behaviour, such as amount of anxiety and depression, was evaluated.

The study found that trauma experienced by the females prior to conception had varied effects on the offspring.

According to Leshem, these effects varied between groups and between male and female offspring; but their behaviour was without doubt different from that of the rats from the control group.

All the offspring of stressed mothers showed reduced social contact compared with that of the control mothers’ offspring: these rats spent less time with one another and interacted less.

In other tests, there were important sex differences. The female rats displayed more symptoms of anxiety, while the males exhibited less anxiety.

Finally, those rats whose mothers became pregnant immediately after being stressed were hyperactive, indicating that how long before pregnancy adversity is experienced, is also important.

“The findings of the present study show that adversity from a mother’s past, even well before her pregnancy, does affect her offspring, even when they are adult,” Leshem said.

The study is published in the journal Developmental Psychology. (ANI)

Vibration plate machines may help weight loss, trim abdominal fat

Washington, May 9 (ANI): Vibration plate exercise machines, if used properly, may help you lose weight and trim the particularly harmful belly fat between the organs, claims a new study.

In a study presented at the European Congress on Obesity, scientists found that overweight or obese people who regularly used the equipment in combination with a calorie restricted diet were more successful at long-term weight loss and shedding the fat around their abdominal organs than those who combined dieting with a more conventional fitness routine.

“These machines are increasingly found in gyms across the industrialized world and have gathered a devoted following in some places, but there has not been any evidence that they help people lose weight. Our study, the first to investigate the effects of vibration in obese people, indicates it’s a promising approach. It looks like these machines could be a useful addition to a weight control package,” said the study’s leader, Dirk Vissers, a physiotherapist at the Artesis University College and the University of Antwerp in Belgium.

To reach the conclusion, Vissers and his colleagues studied the effects of the Power Plate in 61 overweight or obese people – mostly women – for a year. The intervention lasted six months, after which the scientists advised all the volunteers to do the best they could with a healthy diet and exercise regime on their own for another six months. Body measurements, including CT scans of abdominal fat, were taken at the beginning of the study and after three, six and 12 months.

The researchers divided the volunteers into four groups. One group was prescribed an individually calculated calorie restricted diet. Dietician visits were scheduled every fortnight for the first three months and every month for the second three months. The dieters were asked not to engage in any exercise for the duration of the six-month intervention.

A second group received the same diet intervention, with the addition of a conventional fitness regime. They attended supervised exercise classes twice a week for an hour and were urged to exercise on their own a third time each week. The sessions included group cycling, swimming, running, step aerobics and some general muscle strengthening exercises.

A third group got the diet intervention plus supervised vibration plate training instead of conventional exercise. They were asked not to do any aerobic exercise during the six-month intervention phase. The physiotherapists gradually increased the speed and intensity of the machine each week, as well as the variety and duration of the exercises from 30 seconds for each of 10 exercises to 60 seconds for each of 22 exercises, such as squats, lunges, calf raises, push-ups and abdominal crunches.

The average time spent on the machine was 11.9 minutes per session in the first three months and 14.2 minutes in the second three months.

A fourth group got no intervention. There were no significant differences between the groups in obesity and abdominal, or visceral, fat at the start of the study.

“Over the year, only the conventional fitness and vibration groups managed to maintain a 5 percent weight loss, which is what is considered enough to improve health,” Vissers said.

During the first six months, the diet only group lost about 6 percent of their initial body weight, but could not maintain a 5 percent weight loss in the subsequent six months. The group that got diet plus conventional fitness lost about 7 percent of their initial body weight in the first six months, but they didn’t put much of it back on and by the end of the study, they had managed to keep off a 6.9 percent loss.

The vibration group lost 11 percent of their body weight during the intervention phase and by the end of the follow-up period they had maintained a 10.5 percent loss. The control group gained about 1.5 percent of their original body weight.

The vibration group lost 47.8 square centimetres of visceral fat during the first six months and still had a loss of 47.7 square centimetres at 12 months. Visceral fat shrank by 17.6 square centimetres in the conventional fitness group in the first six months, but by the end of the year, it was only 1.6 square centimetres less than at the beginning. The diet group had a visceral fat loss of 24.3 square centimetres after six months and 7.5 square centimetres after a year. (ANI)

Facebook emerges as breeding ground for racists, extremists

London, Apr.23 (ANI): Facebook has become a breeding ground for racists and far-right extremists, according to immigrant leaders and anti-racism campaigners, who believe the site’s owners are not doing enough to clamp down on cyber hate.

More than 200 million people around the world belong to the social networking site, which attracts thousands of new members every day.

According to The Independent, the Federation of Poles in Great Britain has become so disturbed by some of the content online that it has written a letter to Facebook’s owner Mark Zuckerburg, calling on him to close down an anti-Polish group where one member said Polish people should be thrown “down the well”.

Jan Mokrzycki, a spokesman for the federation, said: “Generally we try not to react against every inflammatory gesture against Polish people, but the language within the website was so rude and racist that we felt like we had no choice.”

The sheer size of Facebook’s online community makes monitoring extremists difficult. But a number of groups calling on Britain to throw out, and even kill, foreign nationals have been operating freely for months.

A group called “People hate Pakis” boasts more than 80 members and claims to have been set up by “rebels” from Bradford, where inter-racial tension remains a major problem.

A second group calling itself “Get all the Paki’s [sic] out of England” has more than 140 members, many of whom use racist language which is illegal under laws prohibiting incitement to racial hatred.

Facebook declined to comment yesterday. (ANI)

You’re what your mum did not eat during pregnancy

Washington, Apr 14 (ANI): Researchers from University of Utah have found that lack of proper nutrition in the womb may cause permanent genetic changes in the offspring.

In the study conducted using rats, the researchers found that fetuses receiving poor nutrition in the womb become genetically primed to be born into an environment lacking proper nutrition. As a result, the rats were likely to grow to smaller sizes than their normal counterparts.

They were at higher risk for health problems throughout their lives, such as diabetes, growth retardation, cardiovascular disease, obesity, and neurodevelopmental delays.

“Our study emphasizes that maternal-fetal health influences multiple healthcare issues across generations,” said Robert Lane, professor of pediatric neonatology at the University of Utah, and one of the senior researchers involved in the study.

“To reduce adult diseases such as diabetes, obesity, and cardiovascular disease, we need to understand how the maternal-fetal environment influences the health of offspring,” he added.

During the study, the researchers included two groups of rats. The first group was normal. The second group had the delivery of nutrients from their mothers’ placentas restricted in a way that is equivalent to preeclampsia.

The rats were examined right after birth and again at 21 days (21 days is essentially a preadolescent rat) to measure the amount of a protein, called IGF-1, that promotes normal development and growth in rats and humans.

They found that the lack of nutrients caused the gene responsible for IGF-1 to significantly reduce the amount of IGF-1 produced in the body before and after birth.

The findings are published online in The FASEB Journal. (ANI)

You’re what your mum did not eat during pregnancy

Washington, Apr 14 (ANI): Researchers from University of Utah have found that lack of proper nutrition in the womb may cause permanent genetic changes in the offspring.

In the study conducted using rats, the researchers found that fetuses receiving poor nutrition in the womb become genetically primed to be born into an environment lacking proper nutrition. As a result, the rats were likely to grow to smaller sizes than their normal counterparts.

They were at higher risk for health problems throughout their lives, such as diabetes, growth retardation, cardiovascular disease, obesity, and neurodevelopmental delays.

“Our study emphasizes that maternal-fetal health influences multiple healthcare issues across generations,” said Robert Lane, professor of pediatric neonatology at the University of Utah, and one of the senior researchers involved in the study.

“To reduce adult diseases such as diabetes, obesity, and cardiovascular disease, we need to understand how the maternal-fetal environment influences the health of offspring,” he added.

During the study, the researchers included two groups of rats. The first group was normal. The second group had the delivery of nutrients from their mothers’ placentas restricted in a way that is equivalent to preeclampsia.

The rats were examined right after birth and again at 21 days (21 days is essentially a preadolescent rat) to measure the amount of a protein, called IGF-1, that promotes normal development and growth in rats and humans.

They found that the lack of nutrients caused the gene responsible for IGF-1 to significantly reduce the amount of IGF-1 produced in the body before and after birth.

The findings are published online in The FASEB Journal. (ANI)

Coming soon, a sureshot way to treat constipation

Washington, April 9 (ANI): Suffering from constipation? Well, help is on the way – a team of researchers has identified a potential drug target to make it a lot easier to go to the bathroom, especially when all other methods fail.

They have discovered a group of nerve ending receptors, which, when stimulated, causes the bowels to pass waste, and the specific receptor needed to activate bowel clearance.

Also, they tested chemicals that work with those receptors, providing a blueprint for the development of new laxatives.

“We hope that the receptor identified by our study would be exploited more in the design of drugs to treat constipation,” said Bindu Chandrasekharan, a researcher from Emory University who was involved in the study.

The study involved two groups of mice, focusing on a type of receptor also present on human nerves in the gut (a type of adenosine receptor).

The first group of mice had normal adenosine receptors on these nerves and normal bowel movements. The second group of mice completely lacked these adenosine receptors and showed familiar signs of constipation.

The researchers started with simple experiments such as comparing the wet weight, dry weight, and water content in the stools of both groups.

The mice were also made to drink a dye not absorbed by the body to see how it passed or did not pass.

In addition, the researchers used microscopic lasers to separate the nerve cells from the bowel to determine exactly where the receptors are located. Then they tested various chemicals that can activate or inhibit the nerve receptors.

Gerald Weissmann, M.D, Editor-in-Chief of The FASEB Journal, said: “Here’s why: First, we can look forward to a solution to what is sometimes a serious problem, especially infants and the elderly. Second, it’s the first definitive proof that these receptors, the adenosine receptors, control bowel function. This discovery promises to yield agents that will permit us to sit down and ease up in the middle of a busy day.”

The study has been published online in The FASEB Journal. (ANI)

21st century talks no Roosevelt, Churchill sitting and sipping brandy: Obama

London, Apr.3 (ANI): Visiting US President Barack Obama is of the view that leadership-related negotiations in the new millennium (21st century) are far more complicated and different to the negotiations held 68 years ago during and after the second World War.

Speaking on the sidelines of the second Group of Twenty (G-20) Summit that was held here, Obama said: “If there’s just Roosevelt and Churchill sitting in a room with a brandy, that’s an easier negotiation.”

“But that’s not the world we live in, and it shouldn’t be the world that we live in,” he told reporters from India and China during a news conference following a meeting with Indian Prime Minister Dr. Manmohan Singh.

After over eleven hours of meetings, Obama emerged Thursday from his first summit meeting with a handful of modest concrete commitments.

He did not get much of what American officials had been hoping for, notably failing to persuade other countries to commit to more fiscal stimulus spending.

But he, along with the other world leaders present, did get a more forceful and detailed blueprint for a global recovery than a similar gathering 86 years ago, when an earlier generation failed to take collective action to counter the Great Depression. (ANI)

Obama, Manmohan Singh pitch for enhanced Indo-U.S ties

London, April 2 (ANI): The much-awaited meeting between U.S President Barack Obama and Indian Prime Minister Dr. Manmohan Singh took place here on Thursday on the sidelines of the second Group of 20 (G-20) leaders summit, and at the end of it, both leaders pitched for improved and enhanced bilateral ties.

Both leaders met for about 45-minutes with key aides and used the occasion to highlight each other’s leadership skills and contribution to national and international developments.

President Obama told Prime Minister Singh that the United States sees India: “U.S sees India as a global power and a critical partner in helping to deal with the challenges of 21st century such as in climate change, trade, science and innovation.”

Obama further said : “Much of the growth and rise of India can be attributed to the wisdom of Prime Minister Manmohan Singh.”

Acknowledging Dr. Singh’s leadership in unleashing India’s economic prowess, President Obama said: ” I express my admiration for Prime Minister Singh. I am grateful for the opportunity I had at the summit to have met the Prime Minister Singh. I hope by the time the summit is over I can call him my friend. I hope to visit India in near future”

In his response, Dr. Singh said: “Mr. Obama there is enormous admiration and respect for what you stand for. You are a ray of hope in countries such as ours and indeed the world. Under your distinguished leadership in India-U.S relationship will grow further.”

He further described the United States and India as: “We are two democracies which believe in the rule of law. We are two civil societies. There is hardly any middle class family in India that doesn’t have a son or a daughter, brother or a sister studying in the U.S. This itself is a very important link. We want to further strengthen the India-U.S relations.”

“Under your leadership, we will chart out a new path in dealing with economic issues, climate change, challenges from terror, and how to make the world safe of terror. We will work together in bi-lateral and multi-lateral fora,” Dr.Singh added.

At a personal level, Dr. Singh informed President Obama about a conversation that he had had with his daughter.

When he told his daughter that he would be meeting with Obama, his (Dr.Singh’s) daughter said: “I would cherish if you could get Mr.Obama to autograph the book.”

Dr.Singh told President Obama: “The people of India look forward to your visit to our country and a very warm welcome awaits you, yours wife and daughters.”

Among those who attended Thursday’s bilateral interaction were U.S Secretary of State Hilary Clinton, U.S National Security Advisor James Jones, U.S. Treasury Secretary Timothy Geithner and from the Indian side Deputy Planning Commission Chairman Montek Singh Ahluwalia, National Security Adviser M.K.Naryanan, Foreign Secretary Shiv Shankar Menon and others. By Smita Prakash (ANI)

Report: China sending trade mission to US, AS

BEIJING (AP) China is sending a trade mission to the United States this month ahead of the first meeting of a high-level U.S.-Chinese economic forum since President Barrack Obama took office, a state newspaper said Wednesday. The group will visit Washington, Chicago and San Francisco, the China Daily said.

It gave no details of which industries might be represented or whether they might sign contracts to buy American goods. The trip comes ahead of a meeting of the U.S.-Chinese Strategic Economic Dialogue, a wide-ranging forum held twice a year on economic and trade issues.

No date has been set but China has said Obama and Chinese President Hu Jintao will discuss the format during this week’s G-20 summit in London on the global economic crisis. The last meeting was in December.

Beijing sent similar missions to the United States ahead of past rounds of the dialogue to buy jetliners and other goods in an effort to diffuse trade tensions. In February, a 200-member delegation delegation of Chinese businesspeople and officials visited Europe and the government says it signed contracts worth more than $13 billion in Britain, Germany, Switzerland and Spain.

A second group followed in March to look at investment opportunities in auto manufacturing, textiles, chemicals, energy conservation and other areas. Beijing has described the missions as an effort to expand trade at a time when the global financial crisis is fueling protectionist sentiment.

Childhood abuse raises psychosis risk in women

Washington, Apr 1 (ANI): Women with a history of childhood abuse are twice as likely to suffer from severe mental problem, suggests a new study.

However, the same association has not been found in men, which suggests that both boys and girls respond to traumatic and upsetting experiences differently.

During the study, the researchers looked at people aged 16-64 and divided them into two groups.

Those in the first group had experienced psychotic symptoms, such as hallucinations or delusions and received treatment for depression, mania or schizophrenia.

While the second group had no mental health problems, and acted as a control sample. Both groups were asked whether they experienced physical or sexual abuse during their childhood.

The study showed that women with psychosis were twice as likely to report either physical or sexual abuse compared to healthy women.

One possible explanation, according to researchers could be that girls are more likely to ‘internalise’ difficulties than boys.

In other words, girls who are abused may distance themselves from other people, and become overly suspicious of other people’s behaviour.

This may put them at greater risk of psychotic symptoms in the future, such as paranoid delusions.

However, boys may be more likely to ‘act out’ following physical abuse and potentially be at greater risk for antisocial behaviour.

“These findings do not mean that if a child is abused they will develop psychosis; but women with such disorders are more likely to reveal a background which included childhood abuse,” said lead author Helen Fisher, Researcher in Psychosis at the Institute of Psychiatry at King’s College London.

“These findings point to the need for gender-specific interventions for abused children to prevent later mental health and behavioural problems.

“We also know that there are psychological, biological and genetic factors that may contribute to this condition in women and more attention needs to be given to understanding how adult psychosis develops,” she added.

The study appears in the British Journal of Psychiatry. (ANI)