IDRI and Merial Enter into Research Collaboration

SEATTLE, Wash., and DULUTH, Ga., July 14 /PRNewswire-USNewswire/ — Global animal health company Merial Ltd. and non-profit biotechnology organization the Infectious Disease Research Institute (IDRI) today announce they have agreed to cooperate regarding the research and development of certain vaccines for animals. The agreement consists of a license option agreement and a sponsored research agreement.

Under the agreements, Merial has an option to use IDRI’s proprietary subunit antigens and adjuvant in a particular vaccine and will then be responsible for any vaccine development and commercialization. Further, Merial will sponsor research at IDRI to evaluate the combination of IDRI’s and Merial’s vaccine technologies for second-generation vaccines.

While pharmaceutical companies offer a wide range of vaccines in their portfolios, there are still many unmet needs in animal health. Efficacious and safe vaccines are required to protect not only animals but also humans, who can be vulnerable to many of the same diseases.

“This is a significant step towards aligning the control of diseases that affect both animals and humans,” said Dr. Steven G. Reed, IDRI’s Founder and Head of Research & Development. “This license is the culmination of years of research and serves as an innovative example of the power of public-private partnerships,” added Reed.

Dr Ellen De Brabander, Merial’s Chief Scientific Officer and Head of Global R&D, said: “Merial is very much enthused by the chance to exploit in animal health some of the scientific breakthroughs emerging from IDRI’s research. Combining these opportunities with Merial’s expertise in recombinant platforms is expected to accelerate progress on several key veterinary vaccines.”

Dr. Laurent Fischer of Merial and IDRI’s Dr. Ajay Bhatia will lead the research.

To align with IDRI’s non-profit and charitable mission, the agreements include global access provisions whereby resulting licensed products are guaranteed to be used in developing countries. Separate from this arrangement with Merial, IDRI is developing human vaccines.

About IDRI – Translating science into global health solutions

IDRI is a Seattle-based non-profit organization committed to applying innovative science to the research and development of products to prevent, detect and treat infectious diseases of poverty. By integrating capabilities, IDRI strives to create an efficient pathway bringing scientific innovation from the lab to the people who need it most. For more information, go to www.idri.org.

About Merial

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health, well-being and performance of a wide range of animals. Merial employs approximately 5,600 people and operates in more than 150 countries worldwide. Its 2009 sales were $2.6 billion. Merial is the Animal Health subsidiary of sanofi-aventis. For more information, please see www.merial.com.

SOURCE Infectious Disease Research Institute (IDRI)

Cherry juice could be the new sports drink

Washington, May 29 (ANI): Natural anti-inflammatory power of tart cherries may help ease the pain for people who run, says a new study.

The research from Oregon Health and Science University, which has been presented at the American College of Sports Medicine Conference in Seattle, Wash, showed people who drank tart cherry juice while training for a long distance run reported significantly less pain after exercise than those who didn’t.

In the study of sixty healthy adults aged 18-50 years, those who drank 10.5 ounces cherry juice twice a day for seven days prior to and on the day of a long-distance relay had significantly less muscle pain following the race than those who drank another fruit juice beverage. On a scale from 0 to 10, the runners who drank cherry juice as their “sports drink” had a 2 point lower self-reported pain level at the completion of the race, a clinically significant difference.

While more research is needed to fully understand the effects of tart cherry juice, researchers say the early finding indicate cherries may work like common medications used by runners to alleviate post-exercise inflammation.

“For most runners, post-race treatment consists of RICE (rest, ice, compression and elevation) and traditional NSAIDS (non-steroidal anti-inflammatory drugs),” said Kerry Kuehl, M.D., a sports medicine physician and principal study investigator.

“But NSAIDS can have adverse effects – negative effects you may be able to avoid by using a natural, whole food alternative, like cherry juice, to reduce muscle inflammation before exercise,” the researcher added.

The researchers suggest cherries’ post-exercise benefits are likely because of the fruit’s natural anti-inflammation power – attributed to antioxidant compounds called anthocyanins, which also give cherries their bright red color. (ANI)