1988 pic shows US Fritzl, wife as loving couple

London, Sep 1 (ANI): A picture of American Fritzl, Phillip Garrido, and his wife Nancy, taken in 1988, has portrayed them to be a loving couple.

The picture of Garrido, then 37, and Nancy, 34, shows them hugging one another as they posed for the camera, soon after he had been released from jail on parole for kidnap and rape.

Both had met at Leavenworth prison, Kansas, where he was serving his sentence and she was visiting a relative, and they got married in the jail.

After Garrido got out they had the picture taken to send to his father Manuel, who refused to attend the ceremony.

It was signed on the back: “All our love, Phillip and Nancy Garrido”.

“You can see that he is a very handsome man and you can imagine him dominating Jaycee,” the Sun quoted Manuel as saying.

“Nancy was extremely attractive and would have and did do anything for Phil.

“They look like the typical All-American couple – but when you know Phil like I do you know there is something terrible under the surface,” he added. (ANI)

Janet may be named executor of Jacko’s estate

London, June 29 (ANI): Late King of Pop Michael Jackson’s sister, Janet, may be named executor of his estate, if reports are to be believed.

“She’s in charge, she has the documents, she has control of his stuff,” the Daily Star quoted a relative as saying.

The ‘Thriller’ hitmaker reportedly passed away with debts estimated at 300million pounds.

A New York Post report says that a spokeswoman for Janet has refused to comment on her possibility of being named executor of Jackson’s estate.

Janet was seen arriving on Saturday at her late brother’s rented home in Los Angeles.

She drove up in a Bentley as movers loaded her brother’s belongings into trucks. (ANI)

Jacko’s family started hunting for cash hours after his death, reveals nanny

London, June 28 (ANI): Late King of Pop Michael Jackson’s nanny, Grace Rwaramba, has revealed that she was shocked to see how the ‘Thriller’ star’s family started hunting for cash hours after his death.

The 42-year-old woman, considered to be closest to Jackson and his three children, was in London when she heard the news that the singer had died at a rented Los Angeles home on Thursday.

She says that while preparing to board a plane to fly home and comfort the orphaned kids, she got received a shocking call from one of the Jackson family.

“The relative said, ‘Grace, you remember Michael used to hide cash at the house? I’m here. Where can it be?’” the News of the World quoted her as saying.

“I told them to look in the garbage bags and under the carpets. But can you believe that? They just lost Michael a few hours ago and already one of them is calling me to know where the money is!

“They also told me the children were crying and asking about me. They can’t believe their father died,” she added.

Uganda-born Grace-who has spent five years working as Jackson’s secretary, and 12 as nanny-also spelled out her fears over the orphaned kids Prince, 12, Paris, 11 and seven-year-old Prince Michael II, known to the family as Blanket.

She admitted: “I’m really distraught for them. Michael hadn’t been eating and the kids have been so scared for him. Now the youngest has been saying, ‘Why Daddy? God should have taken me not him.’”

Grace revealed that she fled America to join TV interviewer Barak at her Swiss holiday home after being abruptly sacked by ailing Jackson just two months ago.

She presently finds herself at the centre of the billion-pound custody battle for the children, currently being looked after by Jacko’s mum Katherine, 79. (ANI)

‘Gilani’s fake son-in-law’ is a master forger on the loose in Lahore!

Lahore, June 26 (ANI): Sharing a surname with some famous personalities of the world would obviously make people proud, but in Pakistan, Prime Minister Yousuf Raza Gilani’s name is being utilized by tricksters for fraudulent activities.

Pakistan police has registered a case against a man named, Tasawarul Hassan Gilani for swindling a person while pretending to be a close relative of the prime minister, The Daily Times reports.

Claiming to be the son-in-law of the prime minister, Gilani sold a car having fake documents to a person named Shahzada Ahsan.

Ahsan, who complained about the forgery to the police, said he never thought that he would be cheated by Gilani, as he pretended to be Yousuf Raza Gilani’s close relative.

Ahsan said that surname ‘Gilani’ removed all doubts from his mind.

He added that he was shocked to the core, as the Excise Department confirmed that vehicle’s documents which Gilani had given him were fake.

Ahsan claimed that the ‘fake Gilani’ decamped him after taking 0.6 million rupees for starting a business besides pocketing the car’s price.

The swindler is still out of the police’s clutches. (ANI)

Genetic pathway responsible for plant growth identified by scientists

Washington, May 21 (ANI): Researchers at Iowa State University, US, have discovered a previously unknown genetic pathway in plant cells that regulates plant growth.

Yanhai Yin, an assistant professor in genetics, development and cell biology, Iowa State University, examined signaling mechanisms of a plant hormone called brassinosteroids.

The hormone controls the growth of cells.

“The brassinosteroids (BRs) have a major impact on how large the plant grows,” said Yin.

“Previously, we knew that steroids promote growth,” said Yin. “In model plants like Arabidopsis (a relative of mustard) and crops such as corn and rice, if you have more steroids, you have more growth, and if you have less steroids, you have less growth and the plant is smaller,” he added.

Now, Yin knows that the HERK1 (named for Hercules – the Greek and Roman god who possessed superhuman strength) pathway, induced by BRs, is controlling much of that growth.

There are many other internal and external factors such as light, nutrition and hydration that effect plant growth, but the HERK1, along with some unknown signals, have a great effect.

Yin and his team of Hongqing Guo, assistant scientist; Lei Li, Huaxun Ye, and Xiaofei Yu, all graduate students; and Alexandria Algreen, undergraduate student; have shown that by over-expressing HERK1, they were able to increase a plant’s size by 10 to 15 percent.

By under-expressing HERK1, the plants were about 50 percent smaller.

Now, Yin and his group are trying to find what regulates HERK1 and how HERK1 controls growth.

Understanding what make plants get bigger could be a critical component when producing grain and bio-mass for biofuels.

“With that knowledge, maybe we have one more tool to manipulate corn and rice if we want more grain, or if we want more mass for bio-energy crops,” said Yin. (ANI)

Is Lindsay Lohan a bad influence to sister Ali Lohan’s mental health?

New York, May 6 (ANI): Actress Lindsay Lohan’s critics say that being her sister may harm her sister Ali’s mental health, for the ‘Mean Girls’ star is nowhere a good role model.

Experts believe that the sibling relationship could cause harm to 15-year-old Ali, as Lindsay in no way can make positive life choices.

“If you have an older child who is breaking a lot of the rules and engaging in dangerous and risky behavior, this can have a negative impact on the younger child,” the New York Daily News quoted Dr. Eva Ritvo, psychiatrist and vice chair of psychiatry at the University of Miami School of Medicine, as saying.

“Adolescents are trying to break away from their family and they don’t always make the best choices.

“They’re looking for role models other than their parents, and often turn to peers and older sisters, who can have a very powerful influence on the younger child,” she said.

Impressionable Ali can hardly help but notice Lindsay’s partying, stints in and out of rehab, and her skin-and-bones appearance. But how she reacts to those things could go one of two directions, experts say.

Teens having out-of-control older sibs may copy them, while others fall into the role of trying to protect loved ones from the person.

“You either try to outdo or you become a caretaker,” says Dr. Keith Ablow, psychiatrist and Fox News contributor, who founded the website www.LivingtheTruth.com.

“The course Ali is taking appears to be more in the direction of copying than in shrinking from the cameras and the revelry,” he said.

Psychologist Donna LaMar said that Ali could be helped if a caring adult steps in and offers guidance, support and perspective. That person does not necessarily have to be a relative in order to be effective, she said.

“It could be a teacher or in her case, maybe someone in the business,” LaMar said.

“The person could just say to her, hey what are you doing? What are you searching for and what do you need in your life right now?

“It’s never too late.

“There is always a choice to be made,” she stated.

For now, Ali, who was recently spotted holding Lindsay’s hand as they left West Hollywood’s Chateau Marmont together, appears to be choosing her sister.

“Trying to get what you need as a 15-year-old girl can be a tall order when your sister is very famous and very unpredictable,” Ablow said.

“A 15-year-old should not have to be in the role or either caretaker or competitor, but she should be in a comfortable place where she can become an individual, where she can look at the world with security and choose what defines her,” he added. (ANI)

Hooch death toll set to rise in West Bengal

Tamluk (Kolkata), May 6 (ANI): The death toll in the hooch tragedy in West Bengal is rising as more and more people fell ill.

Unofficial reports say at least 24 people have died in Tamluk region while another 100 people are undergoing treatment at various hospitals. But officials said only 11 died and 30 were hospitalized.

Debashish Sen, Chief Electoral Officer demanded immediate action to stop people from consuming spurious liquor.

“We have taken initiative to check this menace, so that it doesn’t spread. Police and administration should immediately shutdown this business. Not only there but such a move should be carried out across Medinipur district,” said Sen.

A number of victims were admitted to Tamluk government hospital, and 14 of them were said to be critical.

“Every patient who is coming here is dying. People are dying on the way itself. I think whosoever drank the spurious liquor, I believe is dying. About 150-200 people drank it and most of them are now dying,” said Nirmal Mondal, a victim’s relative.

The State Government has ordered an enquiry into the incident and also ordered the closure of all illicit liquor shops in the region.

In January, 27 people had lost their lives and several had fallen ill after consuming illicit liquor in Kidderpore region of West Bengal.

The state police had also arrested six people in connection with the incident. (ANI)

Thieves rob vets while they march to honour dead comrades

Wellington – Thieves robbed a group of New Zealand war veterans Saturday as they marched in honour of their dead comrades on the country’s most sacred day of remembrance, known as Anzac Day. When the vets got back to their Returned and Services’ Associations’ (RSA) club rooms at Waitakere, near Auckland, after the annual dawn service they found 2,600 New Zealand dollars (1,456 US dollars) they collected the day before by selling remembrance poppies on the streets had been stolen.

The money was intended to be spent on welfare benefits for poor veterans of two world wars.

“I just can’t believe they took that from people who gave so much,” local RSA president David Bell told Television New Zealand.

“It’s akin to robbing a soldier’s grave,” said a woman relative of a veteran. (dpa)

Indian comedian Ajay Kumar is world’s smallest actor

London, Apr 23 (ANI): At 2 feet 6 inches, Ajay Kumar, an Indian comedy star, has been officially recognised as the world’s smallest actor.

Hailing from Kerala, Kumar, better known by his stage name Unda Pakru, has made it into the Guinness Book of World Records after starring in 50 films over 13 years.

“There’s no point complaining about being a dwarf. I am small in size but I have got the talent and can work like a normal man,” The Telegraph quoted Ajay as saying.

The tiny actor has not only earned fame and a small fortune through his acting, but is even considered as an eligible bachelor by families seeking a good husband for their daughters.

In 2005, when he married Gayatri, 5ft 1in-who is more than twice her husband’s height-the ceremony was broadcasted on local television across India’s southwestern states.

Ajay said: “We had a traditional arranged marriage. My mother was looking for a match for me when our neighbour said she had a relative with an educated and beautiful daughter.

“My mother arranged the meeting and I liked her, so we got engaged. My five-month-old daughter is a normal size like her mother, so I am very happy.”

“There are hundreds of dwarves like me but they don’t all succeed. It’s about mind, not just the body.” (ANI)

Latvian priest detained for smuggling phone in cake for prisoner

Riga – A priest was arrested in the Latvian capital Riga on Monday for allegedly helping to smuggle a mobile phone hidden inside a traditional Russian Easter cake into prison, the Baltic News Service reported.

The prison chaplain reportedly passed the celebratory “Kulich” pastry to an inmate at Riga Central Prison along with six eggs and an Easter card on behalf of a relative of the convict, according to information released by the Baltic state’s prison service.

Russian Easter cake is traditionally baked for Orthodox Easter, which fell on Sunday and was celebrated by many of Latvia’s large Russian minority.

Usually, ingredients include raisins, nuts, honey and sour cream.

A scan of the items revealed the presence of the contraband communicator. Criminal proceedings have been launched against the chaplain for smuggling illegal items to prison inmates. (dpa)

Obama’s brother denies sex assault on young girls

London, April 13 (ANI): U.S. President Barack Obama’s half brother, Samson, has denied that he had tried to sexually assault a group of young girls in Britain last year.

Samson was refused UK visa when records showed that he had been arrested for attempted sex attack on a group of young girls, including a 13 year-old in Berkshire last November, as per reports.

The 41-year-old, one of the President’s 11 half brothers and sisters by his father who had four partners, was said to have been later fingerprinted but not charged before he left the country.

Samson, however, has allegedly told a UK-based relative, Ian Manners, that he was detained over a pub scuffle, insisting: “I was involved in a pub fight which had nothing to do with any young girls.”

“He would not get involved with 13- year-old girls. It is unthinkable,” the Sun quoted Manners as saying. (ANI)

Lost Darwin ‘evolution egg’ surfaces 200 years on

London, Apr 10 (ANI): An egg collected by Charles Darwin on his five-year voyage on the HMS Beagle in the 1830 and lost for nearly 200 years has been found in a drawer at the University of Cambridge.

The small dark brown egg, with Darwin’s name written on it, was found by Liz Wetton, 80, a volunteer at the Zoology Museum’s bird egg collection.

It bears a large crack, caused after the great naturalist put it in a box that was too small for it, reports The Independent.

The egg is the only one known to exist from Darwin’s Beagle collection.

Researchers have known that Darwin collected 16 bird eggs during his trip between 1831 and 1836 but all were thought to be lost.

The finding was made in February during Wetton’s routine egg sorting.

“The funny thing is that this is Darwin’s year, so the timing is perfect, it couldn’t be better. I’ve always been interested in birds, I’m a bird watcher. And strangely enough, the egg is chocolate-coloured too: when someone in the museum saw it, they said, ‘It’s Darwin’s Easter egg!’” she said.

The egg, which belongs to the common tinamou, a relative of the ostrich, was donated to the museum by Alfred Newton, a friend of Darwin’s who was a professor of zoology at Cambridge.

When the museum’s curators consulted his private notebook, they discovered a reference to the egg which revealed: “One egg, received through Frank Darwin, having been sent to me by his father who said he got it at Maldonado (Uruguay) and that it belonged to the Common Tinamou of those parts. The great man put it into too small a box and hence its unhappy state.” (ANI)

Health dept, docs discuss way out of tricky organ donation issues

CHENNAI: If the blood relative of a brain-dead patient is in need of a vital organ, can the family who is willing to sign papers for donation
demand that the organ be given to the relative? Is the doctor or hospital coordinating a cadaver organ donation liable if the organ retrieved loses it vitality? If the organs of a brain-dead person, the result of a road accident, is removed, will it mean tampering with evidence in a medico-legal case?

These and other related questions came up for a detailed discussion on Saturday when doctors from at least 50 hospitals in Tamil Nadu, mostly licensed transplant centres, met officials from the state health department at a workshop on cadaveric transplantation in Tamil Nadu’, organised by the director of medical services and rural health. The workshop was organised to discuss the Transplant of Human Organs Act 1994 and a series of government orders issued by the health department since January 2008 to promote cadaver transplant.

Over the past six months, the state has seen a rapid increase in organ donation. Forty kidneys, 14 livers, six hearts, 26 corneas, 14 heart valves and skin were harvested from 20 cadavers. Health secretary V K Subburaj said that the meeting was called to discuss problems the network faced in the last six months. “We are sure in the next few months we would be able to streamline the system for cadaver organ donation that would possibly reduce the need for any live donors,” he said.

IT secretary PWC Davidar, instrumental in issuing the government orders (GOs) while he was in the health department, discussed the GOs. “These are not just a set of rules written to be filed as orders. We want every hospital to certify brain death,” he said.

One city-based doctor wanted to know if the donor’s relatives had the right to dictate who the recipient should be. “In one case, the donor’s brother was blind and was waiting for a corneal transplant. They were willing to donate all the organs but requested that one eye be used for his brother. It was tricky situation and we did not know how to handle it,” he said.

Most government officials were for hospitals remaining firm. “With the present rules we don’t have provisions for that. We only encourage voluntary donation with no strings attached,” said Dr J Amalorpavanathan, convenor, cadaver transplant programme.

After hearing out narrations of several incidents, Davidar said that the department would look at options such as passing government orders that could deal with such special situations. “Sometimes, when the donor’s blood relative is in need of an organ, we will have to work it out as well,” he said. “We are also working on orders for organ transplant in medico-legal cases,” he said.

Presently, doctors take in only those cases where the cause of death is ascertained as a road accident. “We also take written consent from the investigating officer that the organ donation will not hamper investigations,” said Dr Amalorpavanathan.

Doctors clarified that no doctor or hospital was legally bound for the viability of the organs before or after transplants. Hospitals agreed to pay Rs 10,000 as annual fee for being a part of the organ sharing network. They decided that a website giving limited information about organ donation and organ sharing would help the public and ensure patient confidentiality.

Asha Goel murder: Lie detector test on accused

MUMBAI: The metropolitan magistrate’s court has granted crime branch the permission to conduct brain mapping and lie detector tests on Praveen
Vatsa, an accused in the Asha Goel murder case. A police team will take Vatsa to the government forensic lab at Bangalore next week.

Asha, a Canada-based doctor, was found murdered in a flat on Malabar Hill on August 23, 2003. She had come to the city to settle property disputes between her brothers, Subhash and Suresh. Asha wanted to ensure that her third brother, Shekhar, got his dues.

In September 2003, the police arrested one Pradeep Parab, whose interrogation led to the arrest of three more persons-Pawankumar Goenka, Manohar Shinde and Narendra Goel. Narendra was Asha’s relative. Vatsa, Narendra’s domestic help, was arrested last week after officials found out that he had lied about his employer’s whereabouts.

Police believe that Vatsa was part of the murder conspiracy. While Suresh died in 2004, the police have sought Interpol’s help to bring in Subhash, who is in Canada.

Teen’s body found near Sangam Vihar

NEW DELHI: A day after the body of a 14-year-old boy was recovered from an animal carcass dump at Ram Pyari camp near Sangam Vihar, the southeast
district police claim to have vital leads and are close to cracking the case. The police have identified the deceased as Sandeep Singh, a resident of Govindpuri. He was a student of class VII at a government school in Kalkaji.

“We hope to solve this case by tomorrow. Based on our investigations, we are almost certain the boy was neither kidnapped from the front of his house nor picked up from near his school. In all probability, he was murdered inside his Govindpuri residence and then dumped at Sangam Vihar. We have ample evidence to prove that a close relative of the boy is involved in the crime. However, we’re confirming certain facts for which we have asked his relatives, including his mother who stays in his native village in UP, to report to us,” said a senior officer investigating the crime.

The Sangam Vihar police had received a call on Thursday evening about a man coming in a three-wheeler and dropping off a gunny bag that was quite heavy. The bag seemed to contain a body and suspicion grew when the driver fled from the scene after locals noticed him. “The boy was wearing a white shirt and blue trousers. He had a vermilion mark on his forehead, but had no footwear on him,” recalled a police source.

The source added that the person who informed PCR had been able to partially note down the number of the three-wheeler. “Based on information provided by him, we are checking all three-wheelers with similar numbers. The boy’s identity was revealed through the ID card he was carrying,” said a senior cop.

The sleuths revealed that so far there have emerged two possible reasons behind the murder “the most probable reason being to stop the kid from revealing an illicit relationship within the family that he had witnessed himself. However, the property angle is also emerging as a major possibility,” said the officer.

When questioned, DCP (southeast) Shalini Singh refused to divulge much in this regard. “We have got vital leads and we’re working on them. It will be premature to draw conclusions right now,” she told Times City.

Chris Brown not applying for university education

Washington, Mar 25 (ANI): Rapper Chris Brown has denied reports that he’s applying for university education.

The rumours started off after the 19-year-old singer was spotted visiting Norfolk State University in his native Virginia at the weekend with mother and cousin.

However, the Kiss Kiss hitmaker has denied the reports, insisting a relative is a prospective student at the University.

A representative for Brown tells TMZ.com the singer visited the college as a “support factor” for his cousin, and has “not applied”, “not enrolled” and is “not interested” in returning to his studies at this point, reports Contactmusic.

Meanwhile, the embattled star is due to be arraigned in a Los Angeles court in April after his alleged bust up with girlfriend Rihanna. (ANI)

New form of destructive terrorist material unlikely

Washington, March 25 (ANI): Scientists have determined that it is highly unlikely that terrorists could produce a new and particularly dangerous form of the explosive responsible for airport security screening of passengers’ shoes.

Gerard Harbison, a chemist at the University of Nebraska-Lincoln, and his team, used computer simulations to analyze a variety of potential peroxide-based explosives in the same chemical class as triacetone triperoxide (TATP).

That powerful, easy-to-make explosive was used by the “shoe bomber,” Richard Reid, in his failed attempt to blow up a transatlantic airline flight in 2001.

Harbison’s team became intrigued by “Internet lore,” reports circulating on the Web claiming creation of another explosive – tetracetone tetraperoxide (TeATeP) – which is reputedly a more lethal relative to TATP.

Initially working on detection methods of peroxide explosives for the Defense Advanced Research Projects Agency, the group instead began to investigate the structure of TeATeP to evaluate likelihood of its use as a terrorist’s weapon.

“Our analysis indicates that potentially new and destructive terrorist materials, which would tax our detection capabilities, may be too unstable for a practical synthesis,” said Harbison.

“We consider it unlikely that any of the previous syntheses were actually successful, and the Internet myths about TeATeP are nothing more than that. So, the good news is basically this is something we don’t have to worry about,” he added.

The group investigated 20 molecular structures of various acetone peroxide compounds and found that all substances larger than TATP are likely too sensitive to be used as weapons.

“The energies we’re seeing in the analysis are extreme enough,” Harbison said, adding that a review of previous TeATeP synthesis reports raised many questions.

“If you look at the actual literature on people who claim to have made TeATeP, it’s very ambiguous. We think probably what happened when people thought they were making TeATeP was that they were actually making TATP,” he added.

According to Harbison, this synthesis error is common and often fatal. When trying to make TATP, a less stable relative, diacetone diperoxide, often is created.

“Using computational chemistry, we can narrow down the domain of potential hazards, things that aren’t going to be on the horizon,” he said.

“I think we now know so much more about not just what works for improvised-explosive-device detection but also what doesn’t work, and we don’t have to try it out experimentally,” he added. (ANI)

Shadows of Saturn’s moons onto its rings signal approach of equinox

Washington, March 24 (ANI): Images taken by the cameras of NASA’s Cassini spacecraft have captured, for the first time, the shadows of Saturn’s moons cast onto its broad expanse of rings, which signals the approach of a phase known as equinox.

Like Earth and most of the other planets, Saturn’s spin axis is tilted relative to its motion around the Sun.

This condition results in the cyclical passage of the Sun, seen from Saturn, from the southern hemisphere to the north and back again, and the full sweep of seasonal changes on Saturn and its rings and moons, over the course of Saturn’s year, equal to 29.5 Earth years.

Thus, about every 15 Earth years, or half-Saturn-year, the Sun passes through the plane containing the planet’s rings.

During these times, the shadows of the planet’s rings fall in the equatorial region on the planet, and the shadows of Saturn’s moons external to the rings, especially those whose orbits are inclined with respect to the equator, begin to intersect the planet’s rings.

When this occurs, the equinox period has essentially begun, and any vertical protuberances within the rings, including small embedded moons and narrow vertical warps in the rings, will also cast shadows on the rings.

At exactly the moment of equinox, the shadows of the rings on the planet will be confined to a thin line around Saturn’s equator and the rings themselves will go dark, being illuminated only on their edge.

The onset of this novel geometry begins with the appearance of the shadows of Saturn’s moons on the icy platform of its rings.

The next equinox on Saturn, when the Sun will pass from south to north, is August 11, 2009.

Because of these unique illumination circumstances, Cassini imaging scientists have been eager to observe the planet and its rings around the time of equinox, and Cassini’s first extended mission, which began on July 1, 2008, and extends to September 30, 2010, was intended to gather observations during this time.

Eventually, more moons will cast shadows on the rings and all shadows will grow longer as exact equinox approaches.

The shadows will be their longest just before and just after equinox when the Sun exactly crosses the ring plane on Aug. 11, 2009.

According to Carolyn Porco, leader of the Cassini imaging team in Boulder, Colorado, “One of the best things about being in orbit around Saturn are those mind-expanding opportunities that arise every now and again to see some celestial phenomenon you couldn’t possibly see here on Earth.” (ANI)

Family history linked to increased blood clot risk

Washington, Mar 24 (ANI): Children and siblings of people with venous thrombosis, or blood clots in the veins, may be more than twice as likely to develop the condition than those without a family history, say Dutch researchers.

Venous thrombosis typically begins in leg veins, although the clot may subsequently break off and travel to the lungs.

“Because universal screening is not cost-effective, research efforts are focused on selection criteria that may be used to increase the chance of finding a genetic risk factor,” the authors write.

“Family history is an evident candidate,” they added.

To reach the conclusion, Irene D. Bezemer, M.Sc., and colleagues at Leiden University Medical Center, Leiden, the Netherlands, collected blood samples and information about family history and environmental risk factors from 1,605 patients who had experienced their first clot between 1999 and 2004.

Their data was compared with that of 2,159 control participants who were the same sex and age but had not had venous thrombosis.

Among patients with venous thrombosis, 505 (31.5 percent) had at least one first-degree relative with a history of the condition, compared with 373 controls (17.3 percent). A positive family history was associated with a more than two-fold increase in the risk of venous thrombosis; the risk was increased further if the relative developed clots at a younger age and as much as quadrupled if more than one relative was affected.

Family history did not correspond well with known genetic risk factors, suggesting that there may be unknown genetic risk factors or that venous thrombosis may cluster in a family due to characteristics of the shared household, the authors note.

“Both in those with and without genetic or environmental risk factors, family history remained associated with venous thrombosis,” the authors write.

“The risk increased with the number of factors identified; for those with a genetic and environmental risk factor and a positive family history, the risk was about 64-fold higher than for those with no known risk factor and a negative family history,” they added.

The relative risk associated with family history was similar to that associated with a genetic risk factor.

The study has been published in the March 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. (ANI)