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Boyden`s Latest Installment in Leadership Series Features Robert Reich

April 6, 2010 By vani Leave a Comment

Legendary US Cabinet Member Shares Perspective on Corporate Leadership, CEO
Compensation and Advantages of Women in the C-Suite -
NEW YORK–(Business Wire)–
Boyden, a global leader in executive search, today released a new installment of
its Boyden Leadership Series featuring an interview with legendary US cabinet
member Robert Reich. The Boyden Reich interview features a thoughtful exchange
on such timely issues as best practices in corporate leadership, CEO
compensation, the role of the Board, motivating global teams and the advantage
of a woman in the corner office.

Robert Reich, currently Professor of Public Policy at the University of
California at Berkeley, is a former US Secretary of Labor and also served
President-Elect Obama`s Transition Advisory Board. He has written twelve books
including his most recent work, Supercapitalism.

“We are very honored to feature Professor Reich in Boyden`s series and share his
perspective on what makes for successful leadership and global workforce
management,” said Trina Gordon, Chairman of Boyden World Corporation and
Managing Director, Boyden Chicago. “Professor Reich`s experience as a pioneering
economist, his experience as one of the ten most successful US cabinet
secretaries of the century and his unique global, multidimensional insight is
valuable to CEOs and aspiring leaders alike.”

In the Boyden interview, Reich discusses key facets of CEO success, including a
practical understanding of the global environment in which their companies
operate, employee motivation, geographical and gender diversity of company
leadership and the opportunity for innovation in the current environment.

“The one benefit from this terrible recession is that it gives top managers the
opportunity to try fundamentally new things,” said Professor Reich in the Boyden
Leadership Series. “Leadership is the art of creating a fabulous team of people
who can come up with innovative solutions and spot new problems and
opportunities quickly, and no individual can do this alone.”

The full interview with Professor Reich is available at www.boyden.com. In
addition, previous issues of Boyden`s Leadership Series including interviews
with David Gergen, Director of Harvard`s Center for Public Leadership and a
former presidential advisor, and James Lillie, President and Chief Operating
Officer of Jarden Corporation, are available on Boyden`s website.

For direct inquiries to Professor Reich, please contact Rebecca Boles at tel: +1
510 642-0560 or rboles@berkeley.edu.

About the Series

The Boyden Leadership Series is a continuing publication that highlights the
views of well-known business leaders on issues relevant to leadership,
management and talent acquisition. The editors of this series conduct interviews
with heads of corporations and other key organizations across the globe to
further growth and idea exchange.

About Boyden World Corporation

Boyden is a global leader in the executive search industry with more than 70
offices in over 40 countries. Founded in 1946, Boyden specializes in high level
executive search, Interim Management and Human Capital consulting across a broad
spectrum of industries. For further information, visit the firm`s website at
www.boyden.com.

Dan Margolis for Boyden
e. dan.margolis@fd.com
t. +1 213 452-6472

Filed Under: International News Tagged With: advantages, chairman, leadership, professor, Women

How to stay fit in flu season

September 20, 2009 By admin Leave a Comment

Washington, Sept 20 (ANI): As cold and flu season approaches, giving up junk food for more healthy options would help maintain a strong immune system.

Dr Ara DerMarderosian, professor of pharmacognosy for University of the Sciences in Philadelphia and an expert in nutraceuticals and natural foods, have provided guidance to change how you eat and break habits that pack on the pounds and compromise immunity.

? Don’t play “food police”

Be conscious of what and how much you eat, but don’t overdo self-monitoring to the point that a healthy lifestyle shifts from being a choice to becoming overwhelming, pushing other activities away and interfering with relationships.

? Pay attention to true hunger

Listen to your hunger signals and refrain from eating when you’re not hungry. Eating when your body doesn’t need food can cause you to overindulge.

? Eat slowly

Eat like a gourmet – enjoy each bite to have, chewing methodically, and truly enjoy the taste of your food. Eating slowly gives your body time to break down the food, which can prevent post-meal indigestion and feeling bloated.

? Focus on eating

Do not watch television, read or work while you eat. When you’re not focused on eating, it’s unlikely you’ll notice how much is going in your mouth.

? Avoid eating when stressed

Stress is a well-known cause of overeating and digestive issues, such as heartburn. A relaxing atmosphere, enjoyable company and conversation, and not feeling rushed for time makes for a healthy meal.

? Everything in moderation

Eating food is pleasurable, so enjoy a few morsels of candy, but limit the quantity. (ANI)

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2000-year-old Roman amphitheatre discovered in Israel

September 20, 2009 By admin Leave a Comment

Washington, September 19 (ANI): A team of archaeologists has discovered a 2000-year-old Roman amphitheatre near Tiberias in Israel.

According to a report in the Haaretz newspaper, Archeologist, Doctor Valid Atrash, from the Israel Antiquities Authority, said that the remnants of the Roman amphitheatre peaks from 15 meters below ground.

The 1990 findings came as a surprise to the archeologists digging near Mount Berniki in the Tiberias hills as there are no references to such a place anywhere in scriptures.

Only at the beginning of 2009, 19-years after the primary discovery, did the uncovering of the theatre in its entirety begin.

The late Professor Izhar Hirshfeld and Yossi Stefanski, the archeologists heading the excavation, initially assessed the remains to belong to the 2nd or 3rd century CE, but quickly realized that they go all the way back to the beginning of the 1st century CE, closer to the founding of Tiberias.

“The most interesting thing about the amphitheatre is its Jewish context,” said Hirshfeld upon the discovery.

“Unlike Tzipori, which was a multi-cultural city, Tiberias was a Jewish city under Roman rule. The findings demonstrate the city’s pluralistic nature and cultural openness, a fact uncommon in those days,” Hirshfeld added.

According to Atrash, in light of the findings, Tiberias appears as particularly liberal for a city that was established over 2000 years ago.

He added that “the theatre was enormous, and being so it attracted a lot of attention. It seated over 7000 people, and appears to have been a prominent landmark for the entire area.”

Zohar Oved, Mayor of Tiberias, said that the discovery of the amphitheatre is undoubtedly “one of the most important findings in the history of the Jewish people” and is planned to open to the public as part of Tiberias archeological gardens in the near future. (ANI)

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HIV uses several routes to escape immune system pressure

September 19, 2009 By admin Leave a Comment

Washington, September 19 (ANI): Researchers at the Emory Vaccine Center have shown that HIV relies upon a number of strategies rather than use any preferred escape route to escape immune system pressure.

The human immune system has the ability to temporarily overpower HIV in early infection.

Studies conducted in the recent past have shown that most newly infected patients develop neutralizing antibodies. These are blood proteins that glob onto the virus and would allow patients to defend themselves – if they were facing only one target.

However, the problem occurs when HIV mutates, and disguises itself enough to get away from the antibodies. The virus eventually wears down the immune system into exhaustion.

The Emory team’s findings attain significance as they suggest that even if any scientist succeeds in identifying a vaccine component that can stimulate neutralizing antibodies, HIV’s capacity for rapid mutation could still be a confounding factor.

Dr. Cynthia Derdeyn, associate professor of pathology at Emory University School of Medicine, Emory Vaccine Center and Yerkes National Primate Research Center, says that a single type of neutralizing antibody may not be enough to contain HIV.

“These neutralizing antibodies work really well – they hit the virus fast and hard. But so far, every time we look, the virus escapes,” she says.

During the study, the researchers took blood samples from the participants a few weeks after infection occurred, and then later as two participants’ immune responses continued.

They isolated individual viruses over the first two years of HIV infection, and tested how well the patients’ own antibodies could neutralize them.

“In one patient where we had very early samples, there was evidence that neutralizing antibody came up within weeks, and that’s earlier than what was previously thought,” Derdeyn says.

In both patients, some viruses mutated part of their outer proteins so that after the mutation, an enzyme would be likely to attach a sugar molecule to it.

Though the sugar molecule interferes with antibody attack, this tactic, known as the “glycan shield”, was not observed in all cases.

Other viruses mutated the part of the outer protein that the neutralizing antibodies stick to directly. In both patients, many changes in the virus’ genetic code were necessary for escape.

“We need to understand early events in the immune response if we are going to figure out what a potential vaccine should have in it. What we can show is that even in one patient, several escape strategies are going on,” Derdeyn says.

According to her, that means that in order to be immune to HIV infection, someone may need to have several types of neutralizing antibodies ready to go.

Seeing how the virus mutates will allow researchers to choose the best parts to put in a vaccine, she says.

The results are online and scheduled for publication in the September issue of the journal Public Library of Science Pathogens.(ANI)

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Negative public opinion about foreign countries an early warning signal for terrorism

September 19, 2009 By admin Leave a Comment

Washington, September 18 (ANI): People’s negative views toward the leadership and policies of other countries may be an indication that a terrorist act may be carried out, say researchers.

Alan Krueger, a Princeton University economist, and Jitka Maleckova, of Charles University in the Czech Republic, came to this conclusion after analysing public opinion polls and terrorist activity in 143 pairs of countries.

Writing about their findings in the journal Science, the researchers say that there is a strong relationship between attitudes expressed toward a foreign country — indicated in surveys on foreign leaders’ performance-and the occurrence of terrorism against that country.

“Public opinion appears to be a useful predictor of terrorist activity,” said Krueger, the Bendheim Professor in Economics and Public Policy.

“This is the first study to relate public opinion across countries to concrete actions such as terrorism,” he added.

He pointed out that the notion that public attitudes can contribute to terrorism has been inadequately explored to date.

According to him, the study’s findings attain significance as they suggest that public opinion may provide a valuable early warning signal of terrorism, and help researchers better understand the causes of terrorism.

The researchers carried out their study by mining public opinion polls of residents in 19 countries in the Middle East and northern Africa conducted by Gallup.

They asked the respondents whether they approved of the job performance of the leaders of nine large countries.

According to the researchers, the countries selected for the study are world powers in terms of size, population or military strength, are the United States, Canada, China, France, Germany, India, Japan, Russia and the United Kingdom.

The opinions, both positive and negative, were linked to the number of terrorist attacks conducted against the nine world powers by people from the 19 countries between 2004 and 2008. The terror attacks were compiled by the National Counterterrorism Center.

Based on the findings, Krueger says that there is not a direct connection between poverty and terrorism, contrary to a popular view.

He adds that economic status has more to do with target countries than it does with the states where the attacks originate.

He says that countries with advanced economies as well as a high degree of civil liberties are most likely to be the targets of terrorism.

The researchers admits that the study does not explain whether terrorists act in response to public opinion or whether they are simply reacting just like the larger public to external events.

However, he insists that, in either case, public opinion surveys can provide a powerful indication of the likelihood of terrorist activity.

Krueger believes that greater disapproval of another country’s leaders or policies may result in more terrorist acts because it increases the number of people who provide material support and encouragement for terrorism, and increases the number of people interested in joining cells and carrying out terrorist acts themselves. (ANI)

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Catalyst simulations for fuel cells may make clean cars a reality

September 19, 2009 By admin Leave a Comment

Washington, Sep 18 (ANI): University of Wisconsin-Madison researchers are working towards developing better catalyst for fuel cells in a bid to make clean cars a reality.

If successful, the researchers could make a car that runs on hydrogen from solar power, and produces water instead of carbon emissions.

Materials science and engineering assistant professor Dane Morgan and Ph.D. student Edward (Ted) Holby have developed a computational model that could optimise an important component of fuel cells, making it possible for the technology to have a more widespread use.

The researchers investigated how particle size is related to the overall stability of a material, and showed with their model that increasing the particle size of a fuel cell catalyst decreases degradation and therefore increases the useful lifetime of a fuel cell.

Fuel cells are electrochemical devices that facilitate a reaction between hydrogen and oxygen, producing electrical power and forming water.

In the type of fuel cells Morgan is researching, called proton exchange membrane fuel cells (PEMFCs), hydrogen is split into a proton and electron at one side of the fuel cell (the anode).

The proton moves through the device while the electron is forced to travel in an external circuit, where it can perform useful work, while at the other side of the fuel cell (the cathode), the protons, electrons and oxygen combine to form water, which is the only waste product.

One of the many hurdles to producing efficient fuel cells for widespread use is the catalyst added to aid the reaction between protons, electrons and oxygen at the cathode.

Current fuel cells use platinum and platinum alloys as a catalyst. While platinum can withstand the corrosive fuel cell environment, it is expensive and not very abundant.

Thus, to maximize platinum use, researchers use catalysts made with platinum particles as small as two nanometers, which are approximately 10 atoms across.

These tiny structures have a large surface area on which the fuel cell reaction occurs.

However, platinum catalysts this small degrade very quickly, which means that the fuel cell doesn’t last long.

The researchers have found a possible solution to the rapid degradation problem-when it comes to catalyst particle size, sometimes smaller isn’t better.

In their modelling work, they showed that if the particle size of a platinum catalyst is increased to four or five nanometers, which is approximately 20 atoms across, the level of degradation significantly decreases.

This means the catalyst and the fuel cell as a whole can continue to function for much longer than if the particle size was only two or three nanometers.

“Fuel cells are just one of many energy technologies – solar, battery, etc. – with enormous potential to reduce our dependence on oil and our carbon emissions. Computer simulation offers a powerful tool to understand and develop new materials at the heart of these energy technologies,” said Morgan. (ANI)

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Susan Sarandon’s daughter Eva Amurri strips for TV show

September 19, 2009 By admin Leave a Comment

Melbourne, Sep 18 (ANI): It seems budding actress Eva Amurri is following in her mother Susan Sarandon’s footsteps, for she is playing the role of a student who turns to stripping in the latest series of US hit show ‘Californication’.

Sarandon was known for doing similar roles more than 20 years ago- in ‘The Hunger’ in 1983, she dropped her clothes for a controversial lesbian love scene with Catherine Deneuve and has never shied away from nudity in films.

And now Eva, 24- born from Sarandon’s relationship with an Italian director during the Eighties- is kick-starting her own acting career in a racy guest appearance on the show.

She stars as Jackie, a student who moonlights in a strip club, during the third season of the show starring David Duchovmy, reports the Daily Telegraph.

The show sees her writhing around Duchovmy’s college professor character Hank Moody, peeling off a corset to dance for him topless.

And later, she is shown at his place taking their relationship to the next level. (ANI)

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Mystery of odd rotating stars solved by scientists

September 19, 2009 By admin Leave a Comment

Washington, September 18 (ANI): A team of scientists has solved a longstanding mystery about a pair of stars called DI Herculis whose peculiar rotation had remained a mystery for three decades.

The shift in the orbit of DI Herculis was a mystery till now.

Now, MIT (Massachusetts Institute Of Technology) researchers and colleagues have determined that the stars are rotating tipped over on their sides, relative to their orbits around each other.

This produces tidal effects that counteract the expected rate for the orbits to shift orientation over time (called precession), finally explaining the mysterious anomaly.

The discrepancy in the rate of precession had been seen as a possible refutation of Einstein’s theory of relativity, so finding a conventional explanation means that relativity has withstood another possible challenge.

This discovery could also help to shed light on how binary stars (about half of all known stars) are formed and how their rotation and orbits evolve over time.

The mystery was solved by postdoctoral researcher Simon Albrecht and assistant professor of physics Joshua Winn and others, who used a high-resolution spectrograph called Sophie on a 1.93-meter telescope at the Observatoire de Haute-Provence in France to make highly detailed observations that revealed the unexpected tilt – one of more than 70 degrees from vertical, the other more than 80 degrees – of the stars’ rotation axes.

The team now hopes to study other unusual binary stars to try to determine how unusual this tipped-over configuration is. (ANI)

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Researchers operate biomedical robots from different locations worldwide via Internet

September 19, 2009 By admin Leave a Comment

Washington, September 18 (ANI): Experts from the University of Washington and SRI International have jointly developed a new software protocol, to standardize the way biomedical robots are managed over the Internet.

Nine research teams from universities and research institutes around the world recently made a successful demonstration of biomedical robots operated from different locations in the U.S., Europe, and Asia with the help of the ‘Interoperable Telesurgical Protocol’.

In a 24-hour period, each participating group connected over the Internet, and controlled robots at different locations.

The tests performed demonstrated how a wide variety of robot and controller designs can seamlessly interoperate, allowing researchers to work together easily and more efficiently.

The demonstration also evaluated the feasibility of robotic manipulation from multiple sites, and was conducted to measure time and performance for evaluating laparoscopic surgical skills.

“Although many telemanipulation systems have common features, there is currently no accepted protocol for connecting these systems. We hope this new protocol serves as a starting point for the discussion and development of a robust and practical Internet-type standard that supports the interoperability of future robotic systems,” said SRI’s Tom Low.

The protocol is expected to allow engineers and designers that usually develop technologies independently, to work collaboratively, determine which designs work best, encourage widespread adoption of the new communications protocol, and help robotics research to evolve more rapidly.

Its early adoption may encourage robotic systems to be developed with interoperability in mind, and avoid future incompatibilities.

“We’re very pleased with the success of the event in which almost all of the possible connections between operator stations and remote robots were successful. We were particularly excited that novel elements such as a simulated robot and an exoskeleton controller worked smoothly with the other remote manipulation systems,” said Professor Blake Hannaford of the University of Washington. (ANI)

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The pen may be mightier than the keyboard for schoolkids

September 17, 2009 By admin Leave a Comment

Washington, September 17 (ANI): It may not be wrong to say that the pen is mightier than the keyboard, for a new study on schoolchildren so suggests.

Virginia Berninger, a University of Washington professor of Educational Psychology, looked at the ability of second, fourth, and sixth grade children to write the alphabet, sentences, and essays using a pen and a keyboard.

“Children consistently did better writing with a pen when they wrote essays. They wrote more and they wrote faster,” said Berninger.

The researcher further said that only for writing the alphabet was the keyboard better than the pen.

Results were mixed for sentences.

However, when using a pen, the children in the three grade levels produced longer essays and composed them at a faster pace.

The study also showed that fourth and sixth graders wrote more complete sentences when they used a pen, and that this ability was not affected by the children’s spelling skills.

The research also showed that many children don’t have a reliable idea of what a sentence is until the third or fourth grade.

“Children first have to understand what a sentence or a complete thought is before they can write one. Talking is very different from writing. We don’t talk in complete sentence. In conversation we produce units smaller and larger than sentences,” Berninger said.

She, however, added: “We need to learn more about the process of writing with a computer, and even though schools have computers they haven’t integrated them in teaching at the early grades. We need to help children become bilingual writers so they can write by both the pen and the computer. So don’t throw away your pen or your keyboard. We need them both.”

She further said: “We need more research to figure out how forming letters by a pen and selecting them by pressing a key may engage our thinking brains differently.” (ANI)

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JRR Tolkien ‘trained as British spy’

September 17, 2009 By admin Leave a Comment

London, Sept 17 (ANI): Lord Of The Rings author JRR Tolkien secretly trained as a British Government spy in the run up to the Second World War, it has emerged.

Tolkien, an Oxford University professor who also wrote The Hobbit, was “earmarked” to crack Nazi codes in 1939.

According to newly released documents, Tolkien was one of 50 intellectuals specially chosen for secret training, reports The Sun.

Tolkien’s involvement with the war effort was revealed for the first time in a new exhibition at GCHQ, the new name for GCCS, the Government’s spy base in Cheltenham, Glos.

The display includes a number of previously unseen exhibits relating to Bletchley Park’s war preparations.

The word “keen” is written on Tolkien’s training file, and it is believed he passed the training course with flying colours.

But he rejected the offer of a job at the famous Bletchley Park code-breaking centre.

A GCHQ historian said: “We simply don’t know why he didn’t join. Perhaps it was because we declared war on Germany and not Mordor.” (ANI)

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Archaeologists discover gemstone carrying portrait of Alexander the Great

September 17, 2009 By admin Leave a Comment

Washington, September 16 (ANI): An archaeological team, during excavations in Israel, has discovered a gemstone that has a portrait of Alexander the Great engraved on it.

The excavations at Tel Dor were carried out by an archaeological team, which was directed by Dr. Ayelet Gilboa of the University of Haifa and Dr. Ilan Sharon of the Hebrew University of Jerusalem.

“Despite its miniature dimensions – the stone is less than a centimeter high and its width is less than half a centimeter – the engraver was able to depict the bust of Alexander on the gem without omitting any of the ruler’s characteristics,” said Dr. Gilboa, Chair of the Department of Archaeology at the University of Haifa.

“The emperor is portrayed as young and forceful, with a strong chin, straight nose and long curly hair held in place by a diadem,” he added.

The Tel Dor researchers have noted that it is surprising that a work of art such as this would be found in Israel, on the periphery of the Hellenistic world.

“It is generally assumed that the master artists – such as the one who engraved the image of Alexander on this particular gemstone – were mainly employed by the leading Hellenistic courts in the capital cities, such as those in Alexandria in Egypt and Seleucia in Syria,” according to the researchers.

“This new discovery is evidence that local elites in secondary centers, such as Tel Dor, appreciated superior objects of art and could afford ownership of such items,” they added.

The significance of the discovery at Dor is in the gemstone being uncovered in an orderly excavation, in a proper context of the Hellenistic period.

This tiny gem was unearthed by a volunteer during excavation of a public structure from the Hellenistic period in the south of Tel Dor, excavated by a team from the University of Washington at Seattle headed by Prof. Sarah Stroup.

Dr. Jessica Nitschke, professor of classical archaeology at Georgetown University in Washington DC, identified the engraved motif as a bust of Alexander the Great.

This has been confirmed by Prof. Andrew Stewart of the University of California at Berkeley, an expert on images of Alexander and author of a book on this topic.

Alexander was probably the first Greek to commission artists to depict his image – as part of a personality cult that was transformed into a propaganda tool. (ANI)

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Study on sheep shows link between personality, survival, and reproductive success

September 17, 2009 By admin Leave a Comment

Washington, September 16 (ANI): Canadian researchers have established a link between personality, survival, and reproductive success by carrying out a study on male bighorn sheep.

Denis Reale, a professor in the Department of Biological Sciences at UQAM and Canada Research Chair in Behavioural Ecology, says that the new study offers insight into personality differences in animals and humans, from an evolutionary perspective.

Since 1969, several teams of researchers have been studying this population of bighorn sheep in Alberta, Canada. They have collected considerable data over the years.

Working in collaboration with researchers from the University of Sherbrooke and the University of Alberta, Reale identified the rams in terms of boldness and docility.

The researchers then conducted paternity tests to determine which rams were reproducing.

They point out that in a system like that of bighorn sheep where there is strong competition among the males for impregnating females, large size and high dominance status are normally key factors in a male’s success.

Males usually attain these conditions in the prime of life, between 6 and 12 years, the researchers say.

However, the paternity tests showed that some young males manage to fertilize females.

The researchers also concentrated on the risk associated with participation in the rut-males can be injured or fall from a cliff in fighting.

Reale and his colleagues hypothesized that the young males that manage to reproduce would be the boldest and most combative, and analysis of the data confirmed it.

However, in exchange for sexual precocity and risk-taking, these rams often die younger than their more docile peers. The latter, instead, invest in the long term, breed later and reach an older age.

Based on their observations, the researchers came to the conclusion that their findings indicate a variation in the personalities and life histories of the population, with two extreme types: one that could be characterised as “live fast and die” and the other as “slow and steady wins the race”.

Depending on their personality, the males managed to breed and to transmit their genes, but in different ways.

The study demonstrates that personality has a direct influence on the lifestyle of individuals.

A research article describing the study has been published in the Journal of Evolutionary Biology. (ANI)

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Popular diabetes drug may help fight breast cancer

September 15, 2009 By admin Leave a Comment

Washington, Sept 15 (ANI): A popular diabetes drug called metformin has been found to be effective in fighting breast cancer.

The findings of the study from Harvard Medical School showed that metformin, along with conventional chemotherapy, shows promise for treating and delaying recurrence of breast cancer.

“We have found a compound selective for cancer stem cells,” said senior author Kevin Struhl, the David Wesley Gaiser professor of biological chemistry and molecular pharmacology at HMS.

“What’s different is that ours is a first-line diabetes drug,” he added.

The drug seemed to work independently of its ability to improve insulin sensitivity and lower blood sugar and insulin levels, all of which are also associated with better breast cancer outcomes.

“There is a big desire to find drugs specific to cancer stem cells,” said Struhl.

“The cancer stem cell hypothesis says you cannot cure cancer unless you also get rid of the cancer stem cells. From a purely practical point of view, this could be tested in humans. It’s already used as a first-line diabetes drug,” he added.

Lead researchers Heather Hirsch and Dimitrios Iliopoulos found that the combination of metformin and the cancer drug doxorubicin killed human cancer stem cells and non-stem cancer cells in culture.

In mice, pre-treatment with the diabetes drug prevented the otherwise dramatic ability of human breast cancer stem cells to form tumours.

In cases where tumours were allowed to take hold for 10 days, the dual therapy also reduced tumour mass more quickly and prevented relapse for longer than doxorubicin alone.

“This is an exciting study,” said Jennifer Ligibel, a medical oncologist at Dana-Farber Cancer Institute and an HMS instructor in medicine, who was not involved in the study.

“There is a lot of interest in studying metformin in breast cancer, but so far we do not have direct evidence that metformin will improve outcomes in patients,” Ligibel said. “That’s what this trial is for.”

The findings appear online in the journal Cancer Research. (ANI)

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Popular stomach acid reducer ups patients’ risk of developing pneumonia threefold

September 15, 2009 By admin Leave a Comment

Washington, September 15 (ANI): Researchers at Wake Forest University School of Medicine have found that a popular stomach-acid reducer, which is used to prevent stress ulcers in critically ill patients who need breathing machine support, triples the likelihood of contracting pneumonia among such patients.

Hospital-acquired pneumonia-the leading cause of infection-related deaths in critically ill patients-increases hospital stays by an average of seven to nine days, cost of care, and the risk of other complications.

“As best we can tell, patients who develop hospital-acquired pneumonia or ventilator-acquired pneumonia have about a 20 to 30 percent chance of dying from that pneumonia. It’s a significant event,” said senior study author Dr. David L. Bowton, professor and head of the Section on Critical Care in the Department of Anesthesiology.

During the study, the researchers compared treatment with two drugs that decrease stomach acid: ranitidine, marketed under the name ZantacTM, and pantoprazole, marketed under the name ProtonixTM or PrilosecTM.

Both drugs decrease stomach acid, but the newer pantoprazole is considered more powerful, and has become the drug of choice in many hospitals.

However, upon the analysis of 834 patient charts, the researchers came to the conclusion that the risk of developing pneumonia was thee times more in the hospitalised cardiothoracic surgery patients who had been treated with pantoprazole.

“We conducted this study, in part, because we thought we were seeing more pneumonias than we were used to having,” said study co-author Marc G. Reichert, pharmacy coordinator for surgery at Wake Forest University Baptist Medical Center.

The researchers say that their study suggests some other steps to keep critically ill patients from developing ventilator-associated pneumonia.

Bowton suggests that doctors consider whether an acid reducer is needed at all, and, in cases where it is needed, ranitidine is recommended because of the apparent decreased risk in developing pneumonia.

Doctors should stop using the drug as soon as the risk of bleeding passes – once the patient is off the breathing machine and eating, either on his/her own or through a feeding tube.

“Stopping the drugs earlier appears to be the best thing for patients,” Reichert said.

The study has been published in a recent issue of CHEST. (ANI)

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Scientists develop ‘electronic nose’ that can sniff out toxins by changing colors

September 14, 2009 By admin Leave a Comment

Washington, September 14 (ANI): A team of scientists has developed a sensor that works as an ‘electronic nose’ in sniffing out some known poisonous gases and toxins, simply by changing colors.

Support for the development and application of this electronic nose comes from the National Institute of Environmental Health Sciences, part of the National Institutes of Health.

Once fully developed, the sensor could be useful in detecting high exposures to toxic industrial chemicals that pose serious health risks in the workplace or through accidental exposure.

While physicists have radiation badges to protect them in the workplace, chemists and workers who handle chemicals do not have equivalent devices to monitor their exposure to potentially toxic chemicals.

The investigators hope to be able to market the wearable sensor within a few years.

“The project fits into the overall goal of a component of the GEI Exposure Biology Program that the NIEHS has the lead on, which is to develop technologies to monitor and better understand how environmental exposures affect disease risk,” said NIEHS Director Linda Birnbaum.

“This paper brings us one step closer to having a small wearable sensor that can detect multiple airborne toxins,” she added.

Kenneth S. Suslick, the M.T. Schmidt Professor of Chemistry at the University of Illinois at Urbana-Champaign, and his colleagues have created what they refer to as an optoelectronic nose, an artificial nose for the detection of toxic industrial chemicals (TICs) that is simple, fast, inexpensive, and works by visualizing colors.

“We have a disposable 36-dye sensor array that changes colors when exposed to different chemicals. The pattern of the color change is a unique molecular fingerprint for any toxic gas and also tells us its concentration,” said Suslick.

“By comparing that pattern to a library of color fingerprints, we can identify and quantify the TICs in a matter of seconds,” he added.

The power of this sensor to identify so many volatile toxins stems from the increased range of interactions that are used to discriminate the response of the array.

To test the application of their color sensor array, the researchers chose 19 representative examples of toxic industrial chemicals.

Chemicals such as ammonia, chlorine, nitric acid and sulfur dioxide at concentrations known to be immediately dangerous to life or health were included.

The arrays were exposed to the chemicals for two minutes.

Most of the chemicals were identified from the array color change in a number of seconds and almost 90 percent of them were detected within two minutes. (ANI)

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Charles Dickens ‘displayed mild OCD symptoms’

September 14, 2009 By admin Leave a Comment

London, Sept 13 (ANI): Charles Dickens developed a ritualistic routine in his domestic life, together with an obsessive approach to work, which is consistent with obsessive compulsive disorder (OCD), and can be seen reflected in some of his characters, claims a new biography.

Dickens had a habit of rearranging furniture whenever he stayed in a hotel room and inspecting his children’s bedrooms every morning, leaving behind notes when he was not satisfied with their tidiness.

According to Michael Slater, emeritus professor of Victorian literature at Birkbeck college, London, and author of the book, Charles Dickens, the genius’ behaviour could be traced to his childhood when poverty forced his family to move home repeatedly, reports The Times.

Slater said: “The disorder of his upbringing may have had the effect on him of wanting to be in control.”

He reckons that Little Dorrit, the main character in Dickens’s novel of the same name, reflected his character.

“There she is, the epitome of neatness, in the squalid atmosphere of the Marshalsea prison making order and making her father comfortable and sweeping and cleaning and tidying all the time,” said Slater.

Slater said there were also signs of OCD in the semi-autobiographical David Copperfield.

Also, when it came to women, the author’s attitude was governed by neatness. (ANI)

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Climate change is faster in Arctic than in any other location on Earth

September 14, 2009 By admin Leave a Comment

Washington, September 13 (ANI): Researchers at the University of Helsinki in Finland have participated in two new studies, which indicate that climate change is progressing faster in Arctic areas than in any other location on Earth.

The study results indicate that the Arctic eco-system has experienced immense changes in the last twenty years.

At many levels, the changes impact the eco-system services that the environment provides for people: the effects extend to the adequacy of natural resources, food production, climate temperature, and result in changes to the landscape.

The changes in the northern nature can be interpreted as an advance warning of what is to be expected on all latitudes.

The results show that spring begins considerably sooner than before.

The blossoming and pollination period of plants starts as much as twenty days sooner in comparison to the situation ten years ago.

Predators are in dire straits because nutrition is now available too soon in relation to the otherwise favourable nesting period.

The distribution of many insects has moved even more north. European winter moths, for example, have destroyed extensive birch areas in Lapland after moving north.

Species invading new areas might supersede the original species in the area, which is already happening to Arctic foxes, which are currently being overrun by red foxes.

Ivory gulls, ringed seals, polar bears and narwhals are examples of species with a small distribution and specialized habitats, and such species will be the first ones to suffer from the changes.

Climate change also has indirect effects that appear in the interaction between different species.

Olivier Gilg and academy professor Ilkka Hanski from the University of Helsinki have teamed up with Benoit Sittler, a researcher from the University of Freiburg, and studied the waning of the previously cyclical population dynamics of the collared lemming in Greenland.

With mathematical models, the researchers showed that the drastic change in the population dynamics of collared lemmings is explained by the fact that snow melts sooner than before.

The lemmings do not procreate as long as before below the snow, and are also easier for predators to hunt.

In addition, frost-melt events in winter form ice layers in the snow layer or at the tundra’s surface, which is why the lemmings are unable to find food like they used to. (ANI)

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Soon, ‘robobees’ that mimic bees’ behaviour

September 14, 2009 By admin Leave a Comment

Washington, Sep 13 (ANI): A Northeastern University neurobiologist is collaborating with Harvard University researchers to develop micro flying robots that will emulate the bees’ brain, body and collective behaviour.

Biology professor Joseph Ayers would create robots, called the robobees, which would mimic the communal feeding behaviour of bee colonies.

The project will draw on the knowledge of computer scientists, engineers, and biologists to construct an electronic nervous system, a supervisory architecture and a high-energy source to power the innovative robots.

“This project will integrate the efforts and expertise of a diverse team of investigators to create a system that far transcends the sum of its parts. We expect substantial advances in basic science at the intersection of these seemingly disparate disciplines to result from this effort,” said Ayers.

Inspired by the biology of the bee and the insect’s colonial behaviour, the project aims to advance miniature robotics and the design of compact high-energy power sources.

The project would also spur innovations in ultra-low-power computing and electronic “smart” sensors that mediate biomimetic control.

In addition, it would refine coordination algorithms to manage multiple, independent machines.

Ayers is widely known for his work in biomimetics- the science of adapting the control systems found in nature to inform design of engineered systems to solve real-world problems-including the development of RoboLobster and RoboLamprey.

The autonomous, biomimetic underwater robotic models emulate the operations of the animals’ nervous systems using an electronic controller based on nonlinear, moving models of neurons and synapses.

“Animals have evolved to occupy every environmental niche where we would hope to operate robots, save outer space. They provide proven solutions to problems that confound even the most sophisticated robots, and our challenge is to capture these performance advantages in engineered devices,” said Ayers. (ANI)

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New method to monitor early sign of oxidative stress that triggers cancer

September 12, 2009 By admin Leave a Comment

Washington, Sept 12 (ANI): Scientists from University of Michigan have developed a new method to monitor early sign of oxidative stress that triggers cancer spread.

Lead researcher Kate Carroll suggests that being able to monitor a marker of oxidative stress that is associated with the activation of tumor cell growth pathways, particularly at an early stage, and then tailor treatments accordingly would allow for more targeted studies and might improve the odds of success with antioxidants and pro-oxidants.

The new method detects sulfenic acid in proteins-a tip off to early oxidative stress and to a specific protein modification associated with cell growth pathways.

Sulfenic acid is produced when a particular oxidant, hydrogen peroxide, reacts with the protein building block cysteine. But because the chemical modification involved is so small and transient, it has been difficult to detect.

To get around that problem, Carroll and Seo used a chemical probe that “traps” sulfenic acid and tags it for recognition by an antibody.

The antibody is labeled with a fluorescent dye that glows when observed with a fluorescence microscope.

The researchers then used the method to assess sulfenic acid levels as a marker of oxidative stress in several systems, including a panel of breast cancer cell lines.

“For each line, we saw a very distinct pattern of sulfenic acid modifications,” indicating different oxidative stress levels and hinting at differences in the underlying molecular events associated with tumor growth,” said Carroll, assistant professor of chemistry and a research assistant professor in the Life Sciences Institute.

“Whether the patterns we see will correlate with response to antioxidant treatment or other therapies that modulate oxidative stress level remains to be seen, but now we at least have a way to investigate that question,” the expert added.

The study appears in Proceedings of the National Academy of Sciences. (ANI)

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