‘Dancing’ algae can ‘waltz’ and ‘minuet’

Washington, April 21 (ANI): Scientists at the Cambridge University, UK, have discovered that freshwater algae can form stable groupings in which they dance around each other, resembling forms like waltz and minuet.

The researchers studied the multicellular organism Volvox, which consists of approximately 1,000 cells arranged on the surface of a spherical matrix about half a millimetre in diameter.

Each of the surface cells has two hair-like appendages known as flagella, whose beating propels the colony through the fluid and simultaneously makes them spin about an axis, miraculously held together only by the fluid flows they create.

The researchers found that colonies swimming near a surface can form two types of “bound states”; the “waltz”, in which the two colonies orbit around each other like a planet circling the sun, and the “minuet”, in which the colonies oscillate back and forth as if held by an elastic band between them.

The researchers have developed a mathematical analysis that shows these dancing patterns arise from the manner in which nearby surfaces modify the fluid flow near the colonies and induce an attraction between them.

The observations constitute the first direct visualisations of the flows, which have been predicted to produce such an attraction.

They have been implicated previously in the accumulation of swimming microorganisms such as bacteria and sperm cells near surfaces.

These findings also have implications for clustering of colonies at the air-water interface, where these recirculating flows can enhance the probability of fertilization during the sexual phase of their life cycle.

According to Professor Raymond E. Goldstein, the Schlumberger Professor of Complex Physical Systems in the Department of Applied Mathematics and Theoretical Physics (DAMTP) and lead author of the study, “These striking and unexpected results remind us not only of the grace and beauty of life, but also that remarkable phenomena can emerge from very simple ingredients.”

This greater understanding of the nature of self-propulsion and collective behaviour of these organisms promises to elucidate key evolutionary steps toward greater biological complexity.

Moreover, the flagella of Volvox are nearly identical to the cilia in the human body, whose coordinated action is central to many processes in embryonic development, reproduction, and the respiratory system.

For this reason, the study of flagellar organisation has potentially broad implications for human health and disease. (ANI)

Pentagon planning to regrow human limbs

Washington, March 27 (ANI): Scientists at the Pentagon have completed the first phase of their plan to regrow soldiers’ limbs, by turning human skin into the equivalent of a blastema – a mass of undifferentiated cells that can develop into new body parts.

Now, researchers are on to phase two: turning that cellular glop into a square inch of honest-to-goodness muscle tissue.

The Worcester Polytechnic Institute (WPI) just got a one-year, 570,000 dollars grant from Darpa, the Pentagon’s blue-sky research arm, to grow the new tissues.

“The goal is to genuinely replace a muscle that’s lost,” biotechnology professor Raymond Page tells Danger Room. “I appreciate that’s a very aggressive goal,” he added.

According to Page, it’s only one part in a larger, even more ambitious Darpa program, Restorative Injury Repair, which aims to “fully restore the function of complex tissue (muscle, nerves, skin) after traumatic injury on the battlefield.”

Muscles are famous for their ability to regenerate. They’re broken down and rebuilt with every gym workout.

But when too much of a muscle is lost – either from injury or illness – “instead of the regenerative response, you get scarring,” Page said.

He’s hoping to get a different result, by carefully growing fresh muscle, outside the body.

Step one will be trying to get those undifferentiated cells to turn into something like muscle cells. That means making sure the cells have myosin and actin – two proteins that are key to forming the cellular cytoskeleton, and to building muscle filaments.

Then, Page and his team will try to get those cells to form around a scaffolding of tiny threads, made of biomaterial. (ANI)