Monkey as butlers’ help maimed US soldiers in Afghanistan lead a normal life

London, May 6 (ANI): American soldiers and officers who were physically disabled while fighting in Afghanistan and Iraq, are being given monkeys as butlers to perform their daily tasks.

The clever capuchins are trained to react to where a laser pen is shined. Provided by a charity, the primate pets help amputees and paralysed soldiers lead normal lives.

Wheelchair-bound Corporal Tim Jeffers, who lost both of his legs, his right eye and part of a hand in Iraq, said of his monkey butler: “He has changed my life and is my best friend.”

Jeffers is among dozens of US war veterans to get a trained primate called Webster, The Sun reports.

He said: “After six months in a military hospital I struggled with daily tasks like turning on a light switch or using a TV remote. But Webster changed all that. He leaps into action at the point of a laser pen and can fetch on command.

“Webster can operate a remote, get objects from a high shelf and open jars of peanut butter.”

The primates, which have been trained at a cost of 30,000 pounds each, are the brainchild of a charity called Helping Hands: Monkey Helpers For The Disabled.

A fund called The Paralysed Veterans of America now provides with much-needed grants.

South American capuchin monkeys were found to be the best primates to train and are also good-natured. Regular monitoring of the creatures ensures their own health and well-being. (ANI)

HIV uses several routes to escape immune system pressure

Washington, September 19 (ANI): Researchers at the Emory Vaccine Center have shown that HIV relies upon a number of strategies rather than use any preferred escape route to escape immune system pressure.

The human immune system has the ability to temporarily overpower HIV in early infection.

Studies conducted in the recent past have shown that most newly infected patients develop neutralizing antibodies. These are blood proteins that glob onto the virus and would allow patients to defend themselves – if they were facing only one target.

However, the problem occurs when HIV mutates, and disguises itself enough to get away from the antibodies. The virus eventually wears down the immune system into exhaustion.

The Emory team’s findings attain significance as they suggest that even if any scientist succeeds in identifying a vaccine component that can stimulate neutralizing antibodies, HIV’s capacity for rapid mutation could still be a confounding factor.

Dr. Cynthia Derdeyn, associate professor of pathology at Emory University School of Medicine, Emory Vaccine Center and Yerkes National Primate Research Center, says that a single type of neutralizing antibody may not be enough to contain HIV.

“These neutralizing antibodies work really well – they hit the virus fast and hard. But so far, every time we look, the virus escapes,” she says.

During the study, the researchers took blood samples from the participants a few weeks after infection occurred, and then later as two participants’ immune responses continued.

They isolated individual viruses over the first two years of HIV infection, and tested how well the patients’ own antibodies could neutralize them.

“In one patient where we had very early samples, there was evidence that neutralizing antibody came up within weeks, and that’s earlier than what was previously thought,” Derdeyn says.

In both patients, some viruses mutated part of their outer proteins so that after the mutation, an enzyme would be likely to attach a sugar molecule to it.

Though the sugar molecule interferes with antibody attack, this tactic, known as the “glycan shield”, was not observed in all cases.

Other viruses mutated the part of the outer protein that the neutralizing antibodies stick to directly. In both patients, many changes in the virus’ genetic code were necessary for escape.

“We need to understand early events in the immune response if we are going to figure out what a potential vaccine should have in it. What we can show is that even in one patient, several escape strategies are going on,” Derdeyn says.

According to her, that means that in order to be immune to HIV infection, someone may need to have several types of neutralizing antibodies ready to go.

Seeing how the virus mutates will allow researchers to choose the best parts to put in a vaccine, she says.

The results are online and scheduled for publication in the September issue of the journal Public Library of Science Pathogens.(ANI)

Some animals can reflect upon, monitor, regulate their states of mind

Washington, September 15 (ANI): Conducting extensive research into animal cognition, psychologists at the University at Buffalo have found that some animals may share humans’ ability to reflect upon, monitor or regulate their states of mind.

“Comparative psychologists have studied the question of whether or not non-human animals have knowledge of their own cognitive states by testing a dolphin, pigeons, rats, monkeys and apes using perception, memory and food-concealment paradigms,” said Dr. J. David Smith, a comparative psychologist at the university.

“The field offers growing evidence that some animals have functional parallels to humans’ consciousness and to humans’ cognitive self-awareness,” he added.

He counts dolphins and macaque monkeys among such species.

Recounting the original animal-metacognition experiment with Natua the dolphin, Smith said: “When uncertain, the dolphin clearly hesitated and wavered between his two possible responses, but when certain, he swam toward his chosen response so fast that his bow wave would soak the researchers’ electronic switches.”

He added: “In sharp contrast, pigeons in several studies have so far not expressed any capacity for metacognition. In addition, several converging studies now show that capuchin monkeys barely express a capacity for metacognition. This last result,” Smith says, “raises important questions about the emergence of reflective or extended mind in the primate order. This research area opens a new window on reflective mind in animals, illuminating its phylogenetic emergence and allowing researchers to trace the antecedents of human consciousness.”

Smith describes metacognition as a sophisticated human capacity linked to hierarchical structure in the mind because the metacognitive executive control processes oversee lower-level cognition, to self-awareness because uncertainty and doubt feel so personal and subjective, and to declarative consciousness because humans are conscious of their states of knowing and can declare them to others.

Therefore, Smith says: “It is a crucial goal of comparative psychology to establish firmly whether animals share humans’ metacognitive capacity. If they do, it could bear on their consciousness and self-awareness, too.”

He concludes, “Metacognition rivals language and tool use in its potential to establish important continuities or discontinuities between human and animal minds.”

A research article describing his study has been published in the journal Trends in Cognitive Science. (ANI)

What makes us uniquely human

Washington, Sept 2 (ANI): In a remarkable piece of detective work, scientists working at Trinity College Dublin have discovered three genes that are unique to humans.

In the study published online in Genome Research, boffins have made a crucial discovery of genes that have evolved in humans after branching off from other primates.

In the field of molecular evolution, the prevailing wisdom was that new genes could only evolve from duplicated or rearranged versions of preexisting genes. It seemed highly unlikely that evolutionary processes could produce a functional protein-coding gene from what was once inactive DNA.

However, recent evidence suggests that this phenomenon does in fact occur. Researchers have found genes that arose from non-coding DNA in flies, yeast, and primates. No such genes had been found to be unique to humans until now, and the discovery raises fascinating questions about how these genes might make us different from other primates.

Now, in the latest study, David Knowles and Aoife McLysaght of the Smurfit Institute of Genetics at Trinity College Dublin undertook the task of finding protein-coding genes in the human genome that are absent from the chimp genome. Once they had performed a rigorous search and systematically ruled out false results, their list of candidate genes was trimmed down to just three. Then came the next challenge.

“We needed to demonstrate that the DNA in human is really active as a gene,” said McLysaght.

The authors gathered evidence from other studies that these three genes are actively transcribed and translated into proteins, but furthermore, they needed to show that the corresponding DNA sequences in other primates are inactive. They found that these DNA sequences in several species of apes and monkeys contained differences that would likely disable a protein-coding gene, suggesting that these genes were inactive in the ancestral primate.

The authors also note that because of the strict set of filters employed, only about 20 percent of human genes were amenable to analysis. Therefore they estimate there may be approximately 18 human-specific genes that have arisen from non-coding DNA during human evolution. (ANI)

Early life nurturing influences social behaviors in adulthood

Washington, Sept 1 (ANI): A new study, conducted by researchers at the Yerkes National Primate Research Center, Emory University, has shown that early life nurturing impacts later life relationships.

The researchers used prairie voles as a model to understand the neurochemistry of social behavior.

Prairie voles are small, highly social, hamster-sized rodents that often form stable, life-long bonds between mates.

By influencing early social experience in prairie voles, researchers gained insight into what aspects of early social experience drive diversity in adult social behavior.

In the wild, there is striking diversity in how offspring are reared. Some pups are reared by single mothers, some by both parents and some in communal family groups.

For the study, Todd Ahern, a graduate student in the Emory University Neuroscience Program, and Larry Young, PhD, professor of psychiatry and behavioral sciences at the Yerkes Research Center and Emory University School of Medicine, compared pups raised by single mothers (SM) to pups raised by both parents (BP) to determine the effects of these types of early social environments on adult social behavior.

“Our findings demonstrate that SM- and BP-reared animals experienced different levels of care during the neonatal period and that these differences significantly influenced bonding social behaviors in adulthood,” Ahern said.

Young added: “These results suggest naturalistic variation in social rearing conditions can introduce diversity into adult nurturing and attachment behaviors. SM-raised pups were slower to make life-long partnerships, and they showed less interest in nurturing pups in their communal families.

The researchers also found differences in the oxytocin system. Oxytocin is best known for its roles in maternal labor and suckling, but, more recently, it has been tied to prosocial behavior, such as bonding, trust and social awareness.

“Very simply, altering their early social experience influenced adult bonding,” Ahern said.

Further studies will look at the altered oxytocin levels in the brain to determine how these hormonal changes affect relationships.

The study is currently available online in a special edition of Frontiers in Behavioral Neuroscience. (ANI)

Gene breakthrough could banish inherited diseases

London, Aug 26 (ANI): Researchers at Oregon Health and Science University’s Oregon National Primate Research Center (ONPRC) have developed a new technique that could banish a host of crippling inherited diseases forever.

The landmark research raises the prospect of wiping out diseases passed on from mothers to their children through mutated DNA in cell mitochondria.

“We believe this discovery in nonhuman primates can rapidly be translated into human therapies aimed at preventing inherited disorders passed from mothers to their children through the mitochondrial DNA, such as certain forms of cancer, diabetes, infertility, myopathies and neurodegenerative diseases,” said Shoukhrat Mitalipov, from Oregon Health and Science University (OHSU).

Mitochondria are structures that are found in all cells that provide energy for cell growth and metabolism, which is why they are often called the cell’s “power plant.”

The structures produce energy to power each individual cell. Mitochondria also carry their own genetic material.

When an egg cell is fertilized by a sperm cell during reproduction, the embryo almost exclusively inherits the maternal mitochondria present in the egg. This means that any disease-causing genetic mutations that a mother carries in her mitochondrial DNA can be passed on to her offspring.

OHSU researchers’ method transfers the mother’s chromosomes to a donated egg that has had its chromosomes removed, but which has healthy mitochondria, thereby preventing the disease from being passed on to one’s offspring.

During the research, scientists collected groups of unfertilized eggs from two female rhesus macaque monkeys (monkeys A and B). They then removed the chromosomes, which contain the genes found in the cell nucleus, from the eggs of monkey B, and then transplanted the nuclear genes from the eggs of monkey A into the eggs of monkey B.

Then the eggs from monkey B, which now contained their own mitochondria but monkey A’s nuclear genes, were fertilized. The fertilized eggs developed into embryos that were implanted in surrogate monkeys.

The initial implantation of two embryos resulted in the birth of healthy twin monkeys. These monkeys are the world’s first animals derived by spindle transfer.

Follow-up testing showed that there was little to no trace of cross-animal mitochondrial transfer using this procedure. This shows that the researchers were successful in isolating nuclear genetic material from mitochondrial genetic material during the transfer process.

“In theory, this research has demonstrated that it is possible to use this therapy in mothers carrying mitochondrial DNA diseases so that we can prevent those diseases from being passed on to their offspring,” Mitalipov said.

“We believe that with the proper governmental approvals, our work can rapidly be translated into clinical trials for humans, and, eventually, approved therapies,” Mitalipov added.

The research has been published in the Aug. 26 advance online edition of the journal Nature. (ANI)

Key feature of immune system survived in humans for 60 million years

Washington, August 19 (ANI): A new study has concluded that one key part of the immune system survived in the humans and other primates for almost 60 million years.

Researchers at the Oregon State University (OSU) and the Cedars-Sinai Medical Center in the US carried out the study.

They found out that one key part of the immune system, the ability of vitamin D to regulate anti-bactericidal proteins, is so important that is has been conserved through almost 60 million years of evolution and is shared only by primates, including humans – but no other known animal species.

The fact that this vitamin-D mediated immune response has been retained through millions of years of evolutionary selection, and is still found in species ranging from squirrel monkeys to baboons and humans, suggests that it must be critical to their survival, according to researchers.

Even though the “cathelicidin antimicrobial peptide” has several different biological activities in addition to killing pathogens, it’s not clear which one, or combination of them, makes vitamin D so essential to its regulation.

The research also provides further evidence of the biological importance of adequate levels of vitamin D in humans and other primates, even as some studies and experts suggest that more than 50 percent of the children and adults in the US are deficient in “the sunshine vitamin.”

“The existence and importance of this part of our immune response makes it clear that humans and other primates need to maintain sufficient levels of vitamin D,” said Adrian Gombart, an associate professor of biochemistry and a principal investigator with the Linus Pauling Institute at Oregon State University.

In the new study, researchers from OSU and the Cedars-Sinai Medical Center describe the presence of a genetic element that’s specific to primates and involved in the innate immune response.

They found it not only in humans and their more recent primate ancestors, such as chimpanzees, but also primates that split off on the evolutionary tree tens of millions of years ago, such as old world and new world primates.

The genetic material – called an Alu short interspersed element – is part of what used to be thought of as “junk DNA” and makes up more than 90 percent of the human genome.

In this case, the genetic element is believed to play a major role in the proper function of the “innate” immune system in primates – an ancient, first line of defense against bacteria, viruses and other pathogens. (ANI)

Why male and female lemurs are of same size

Washington, July 15 (ANI): Rice University biologist Amy Dunham has put forward a new theory for one of primatology’s long-standing mysteries-why are male and female lemurs the same size?

In most primate species, males have evolved to be much larger than females, but this has not been found to be true in case of lemurs.

Some theories have suggested that environment played a role or that lemur social development was altered due to the extinction of predatory birds.
“Scientifically, this is quite a big question that researchers have debated for over 20 years. I actually started doing research on lemurs as an undergraduate, working in Ranomafana (National Park in Madgascar), and the question about size monomorphism has bugged me since then,” said Dunham.
In the new study, Dunham has offered one of the first new theories on lemur monomorphism in more than a decade.
After conducting an exhaustive review of the observational work done on lemurs, Dunham concluded that male lemurs do guard their mates, just like other primates.

But unlike gorillas and other primates that fight for mating rights with females, male lemurs have evolved to passively guard their mates.
They do this by depositing a solid plug inside the female’s reproductive tract just as they finish mating. The plug is deposited as a liquid protein but quickly hardens and stays in place for a day or two.

Since many female lemurs are sexually responsive to males for only one day out of the entire year, the plug serves the purpose of preventing other males from mating with the female, while also freeing the male to mate with other females during the brief time they are available.
“If the female has a short receptivity period, as most lemurs do, then we hypothesize that this is likely to be an advantageous strategy,” said Dunham.
To test their hypothesis, the researchers examined 62 primate species and found that copulatory plugs were most likely to occur in species where female sexual receptivity was very brief and where males and females were the same size.

This was true both for lemur species and for a few other species, like South American squirrel monkeys.
The study has been published in the Journal of Evolutionary Biology. (ANI

German zoo renames baboon called Obama after racist claims

London, July 11 (ANI): A zoo in Germany has reportedly renamed a baby baboon from Obama to Okeke, after being accused of racism.

The Dresden Zoo was said to have named the baby mandrill after the US President, while being caught up in Obama-mania.

According to a report in The Local, a black advocacy group slammed the move, accusing the zoo of racial insensitivity, and demanded that the animal be renamed, reports The Telegraph.

Manuela Collmar, keeper at the zoo’s Afrika Haus, said that names of all newborn were marked with the same letter each year, and the mandrill’s case was no exception.

She defended the name saying that Obama was “meant to be positive and an honour in light of his visit to Dresden in June.”

Director Karl-Heinz Ukena also denied racist claims, and apologised for any harm caused.

The primate will now be called Okeke, which Ukena says means “he who was born on market day”. (ANI)

Chimps can learn to make their own tools watching video demos

London, July 1 (ANI): St Andrews University researchers in Scotland have shown that chimpanzees can be learn how to make their own tools by watching demonstrations on video.

For this work, the researchers trained a chimpanzee to make a long pole for prizing out-of-reach fruit from a tree, and then filmed the animal constructing the handy tool from a variety of different parts.

They say that watching a video of the feat, other chimps were also able to make their own similar tools.

Elizabeth Price, who led the study at the university’s School of Psychology, said that she wanted to discover whether chimps could learn to make a tool from separate parts after watching other animals use materials to improve their lives.

She pointed out that some birds are able to use twigs to pull grubs out of hiding places, and monkeys have been known to strip leaves from branches to fish for termites.

According to her, the findings of her study are “the first evidence that chimpanzees can socially learn how to construct tools,” and show that the animals are more intelligent than previously thought.

“It is very exciting as we didn’t know chimps could do this,” the Scotsman quoted her as saying.

“You could say the videos were like Blue Peter and ‘Here’s one I made earlier’.

“The chimps really needed to see the full instructional video to learn how to make the long tool and gain the reward.

“Most of those who didn’t watch the video, couldn’t make the tool,” she added.

Along with Professor Andrew Whiten of St Andrews University, Elizabeth led an international team of primate experts to uncover the remarkable learning feats of the chimpanzees.

The researchers presented chimpanzees in a primate centre at the University of Texas with a grape that was just out of reach.

They showed some chimps a video of another chimpanzee expertly slotting one stick into another to create a rake, and then using the tool to get the fruit.

Others were shown a shorter video showing a chimpanzee using a ready-made tool.

The researchers found chimpanzees that watched the full video demonstration were able to copy what they saw, and make the tools themselves.

In a follow-up test, since the grapes were put within reach, the use of a longer tool was unnecessary.

The researchers observed that the chimps that had learnt the skill by watching the full video persisted in making the rake, which in the new scenario was more awkward to use.

However, a few individual chimps that had watched the shorter video still managed to make a tool, did not do so when the grape was close enough to reach without help.

Elizabeth said: “These results are important not only because they provide the first evidence that chimpanzees can socially learn how to construct tools, but also because they suggest that social learning can have a potent effect on how an individual approaches related problems later.”

Based on the observations made during the study, she came to the conclusion that learning from others can lead to a less flexible approach to novel situations.

She and her colleagues are now planning to discover the extent to which our own species is vulnerable to a similar effect, by looking at children’s abilities.

Elizabeth added: “Social learning plays a major role in the spread of complex technologies in humans.”

The research has been published in the online edition of the journal Proceedings of the Royal Society B. (ANI)

Primates evolved larger brains to hop between trees

Washington, July 1 (ANI): A new study, in which scientists scanned a 54-million-year-old skull roughly the size of a walnut, has suggested that primates such as lemurs, monkeys, apes, and humans might have evolved larger brains as a result of the need to move quickly from tree to tree.

According to a report in National Geographic News, the 1.5-inch-long (4-centimeter-long) skull belongs to the long-gone Ignacius graybullianus, described as a cousin of our earliest ancestors, which arose less than ten million years after the dinosaurs vanished.

Discovered in Wyoming roughly 25 years ago, the fossil “is the most complete early primate skull known,” said study co-author Jonathan Bloch, a vertebrate paleontologist at the University of Florida.

Due to its completeness and age, the skull gives us the clearest idea yet what early primates were like, according to the researchers.

After taking more than 1,200 detailed X-ray images of the skull, researchers combined them to help create a 3-D model of Ignacius’ brain.

The model showed a brain just one-half to two-thirds the size of the smallest modern primate brain, the study said.

It seems that such a small brain was enough for tree dwelling and fruit seeking.

Ignacius’ teeth, for example, suggest it had a fruit diet, while the animal’s claws and flexible joints hint at tree dwelling.

The finding therefore reopens the question of what triggered the evolution of large brains in later primate species, if not branch living or fruit eating?

One activity Ignacius seems unsuited for is jumping from tree to tree, as opposed to simply climbing branches.

In primates, this type of leaping generally requires long hind limbs, large inner-ear organs linked to balance-and strong visual processing.

Instead of a robust center of vision, Ignacius’ brain had large lobes dedicated to smelling, the model suggests.

The prehistoric primate “was mostly a nose-first animal that relied on smell instead of sight, unlike modern primates, which have far more developed visual processing areas,” explained lead study author Mary Silcox, a vertebrate paleontologist at the University of Winnipeg.

“For primates, stepping up vision would have been key for leaping safely,” she surmised.

But, to do that, the brain had to be larger, which eventually happened as a result of evolution. (ANI)

Common ancestor of humans and monkeys evolved from primates in Asia

Washington, July 1 (ANI): A new fossil primate from Myanmar suggests that the common ancestor of humans, monkeys and apes evolved from primates in Asia, not Africa, as was earlier believed by researchers.

A major focus of recent paleoanthropological research has been to establish the origin of anthropoid primates (monkeys, apes and humans) from earlier and more primitive primates known as prosimians (lemurs, tarsiers and their extinct relatives).

Prior to recent discoveries in China, Thailand, and Myanmar, most scientists believed that anthropoids originated in Africa.

Earlier this year, the discovery of the fossil primate skeleton known as “Ida” from the Messel oil shale pit in Germany led some scientists to suggest that anthropoid primates evolved from lemur-like ancestors known as adapiforms.

According to Dr. Chris Beard, a paleontologist at Carnegie Museum of Natural History in Pittsburgh, Pennsylvania and a member of the international team of researchers behind the Myanmar anthropoid findings, the new primate, Ganlea megacanina, shows that early anthropoids originated in Asia rather than Africa.

These early Asian anthropoids differed radically from adapiforms like Ida, indicating that Ida is more closely related to modern lemurs than it is to monkeys, apes and humans.

The 38-million-year-old Ganlea megacanina fossils, excavated at multiple sites in central Myanmar, belong to a new genus and species.

Heavy dental abrasion indicates that Ganlea megacanina used its enlarged canine teeth to pry open the hard exteriors of tough tropical fruits in order to extract the nutritious seeds contained inside.

“This unusual type of feeding adaptation has never been documented among prosimian primates, but is characteristic of modern South American saki monkeys that inhabit the Amazon Basin,” said Dr. Beard.

“Ganlea shows that early Asian anthropoids had already assumed the modern ecological role of modern monkeys 38 million years ago,” he added.

Ganlea and its closest relatives belong to an extinct family of Asian anthropoid primates known as the Amphipithecidae.

Two other amphipithecids, Pondaungia and Myanmarpithecus, were previously discovered in Myanmar, while a third, named Siamopithecus, had been found in Thailand.

A detailed analysis of their evolutionary relationships shows that amphipithecids are closely related to living anthropoids and that all of the Burmese amphipithecids evolved from a single common ancestor. (ANI)

Eyes have given us real ‘superpowers’, says expert

Washington, June 20 (ANI): Making a startling discovery, a scientist has claimed in his new book that the evolution of vision has provided humans with four real superpowers: telepathy, X-ray vision, seeing the future, and speaking with the dead.

And, as it turns out, these superpowers have been instrumental in shaping the way people interact with one another and see the world.

Mark Changizi, a neurobiology expert and assistant professor in the Department of Cognitive Science at Rensselaer Polytechnic Institute, has detailed the most basic scientific assumptions about human vision in his book, titled ‘The Vision Revolution: How the Latest Research Overturns Everything We Thought We Knew About Human Vision’.

“Our brains don’t come with user’s manuals listing all the powers we’re capable of – much of what our eyes can do is still not yet known. That’s why I think this is new, important, exciting stuff, because we are still today learning about powers we didn’t even know we have,” said Changizi.

The new book is a guided tour in which Changizi sets out to answer four misleadingly simple questions-Why do we see in colour? Why do our eyes face forward? Why do we see illusions? And why does reading come so naturally to us?

The short answers of the above questions are-because we are telepathic, because we have X-ray vision, because we can see into the future, and because we can commune with the dead.

However, the longer answers are more like that of Charles Darwin, for example, our X-ray vision is actually advanced binocular vision that developed to allow our primate ancestors to see the forest through a vast clutter of leaves and trees.

Our telepathy is actually our colour vision, which evolved to allow us to sense the emotions on the faces of others.

And our clairvoyance is actually an ages-old hack that enables our minds to compensate for the one-tenth of a second lag between when we see something and when our brain receives the visual information.

In The Vision Revolution, Changizi has tackled the four questions with a unique, interdisciplinary perspective.

A self-described “square, stick-in-the-mud, pencil-necked scientist,” he has employed humour, a sprinkling of pop culture references, and intuitive everyday analogies to paint a rich picture of leading-edge theoretical neuroscience and evolutionary biology.

“In targeting the book toward non-experts as well as my research peers, I believe it becomes more exciting for both kinds of readers.

Non-experts don’t want a book written just for non-experts. They want to read a book they know is genuinely part of the scientific conversation. And experts don’t always need to have all the enjoyment sucked out of their readings, as in most journal articles,” said Changizi.

The new book, which hit store shelves this month, is published by BenBella Books. (ANI)

How the brain processes speech

London, May 27 (ANI): A review of human and non-human primate studies suggests that scientists are very close to forming a conclusive theory about the brain processes speech and language.

Dr. Josef Rauschecker of Georgetown University and his co-author Sophie Scott, a neuroscientist at University College, London, say that both human and animal studies have confirmed that speech is processed in the brain along two parallel pathways, each of which run from lower- to higher-functioning neural regions.

The authors describe these pathways as the “what” and “where” streams, which are similar to how the brain processes sight, but are located in different regions.

Both pathways begin with the processing of signals in the auditory cortex, located inside a deep fissure on the side of the brain underneath the temples – the so-called “temporal lobe”.

Information processed by the “what” pathway then flows forward along the outside of the temporal lobe, and the job of that pathway is to recognize complex auditory signals, which include communication sounds and their meaning (semantics).

The “where” pathway is mostly in the parietal lobe, above the temporal lobe, and it processes spatial aspects of a sound – its location and its motion in space – but is also involved in providing feedback during the act of speaking.

Rauschecker says that auditory perception – the processing and interpretation of sound information – is tied to anatomical structures.

“Sound as a whole enters the ear canal and is first broken down into single tone frequencies, then higher-up neurons respond only to more complex sounds, including those used in the recognition of speech, as the neural representation of the sound moves through the various brain regions,” he says.

“In both species, we are using species-specific communication sounds for stimulation, such as speech in humans and rhesus-specific calls in rhesus monkeys. We find that the structure of these communication sounds is similar across species,” he adds.

Rauschecker believes that the findings of this research may ultimately yield some valuable insights into disorders that involve problems in comprehending auditory signals, such as autism and schizophrenia.

“Understanding speech is one of the major problems seen in autism, and a person with schizophrenia hears sounds that are just hallucinations. Eventually, this area of research will lead us to better treatment for these issues,” Rauschecker says.

The study is published in the June issue of Nature Neuroscience. (ANI)

47-mln-yr-old fossil “missing link” between humans and lemurs

Washington, May 20 (ANI): The analysis of a 47-million-year-old fossil, dubbed “Ida”, has led paleontologists to suggest that it is a critical “missing link” species in primate evolution, which connects humans and lemurs.

According to a report in National Geographic News, in a new book, documentary, and promotional Web site, paleontologist Jorn Hurum, who led the team that analyzed the 47-million-year-old fossil, suggests that the fossil bridges the evolutionary split between higher primates such as monkeys, apes, and humans and their more distant relatives such as lemurs.

“This is the first link to all humans,” said Hurum, of the Natural History Museum in Oslo, Norway. “Ida represents the closest thing we can get to a direct ancestor,” he added.

Ida, properly known as Darwinius masillae, has a unique anatomy.

The lemur-like skeleton features primate-like characteristics, including grasping hands, opposable thumbs, clawless digits with nails, and relatively short limbs.

“This specimen looks like a really early fossil monkey that belongs to the group that includes us,” said Brian Richmond, a biological anthropologist at George Washington University in Washington, D.C.

Richmond noted that there’s a big gap in the fossil record from this time period.

Researchers are unsure when and where the primate group that includes monkeys, apes, and humans split from the other group of primates that includes lemurs.

“Ida is one of the important branching points on the evolutionary tree, but it’s not the only branching point,” Richmond said.

At least one aspect of Ida is unquestionably unique: her incredible preservation, unheard of in specimens from the Eocene era, when early primates underwent a period of rapid evolution.

“From this time period there are very few fossils, and they tend to be an isolated tooth here or maybe a tailbone there,” Richmond explained.

“So you can’t say a whole lot of what that (type of fossil) represents in terms of evolutionary history or biology,” he added.

In Ida’s case, scientists were able to examine fossil evidence of fur and soft tissue and even picked through the remains of her last meal: fruits, seeds, and leaves.

What’s more, the newly described fossil was unearthed in Germany’s Messel Pit.

According to Richmond, Ida’s European origins are intriguing, because they could suggest-contrary to common assumptions-that the continent was an important area for primate evolution. (ANI)

Mexico City revives small pox rituals for modern flu

Mexico City – The bells of Mexico City’s cathedral rang in prayer, and the figure of Our Father Jesus of Health was taken out onto the streets of the city’s historic centre Sunday for the first time in 150 years to ask God for protection.

As in the times of smallpox, Roman Catholics joined in prayer against the ongoing flu epidemic, including cases of swine flu, that has left 149 people dead in the country in less than a month.

They had good reason. The streets and metro system of the nation’s capital turned ghostly as residents donned face masks, handed out by the Mexican army. Football games were played in empty stadiums. Schools were closed until May 6 and other public gatherings were shut down.

Additional worry came from a 5.7-scale earthquake that shook the city to its bones Monday and sent masked workers fleeing from buildings. Fortunately for the city, it was spared the added insult of physical damage from the temblor.

But times are different from the 16th century Aztecs of the ancient Tenochtitlan who had to face the smallpox brought ashore by the Spaniards. They are different from the later devastating epidemics of measles, cholera or mumps.

In fact, residents of Mexico City have many better weapons against disease – face masks, anti-viral drugs, modern communications and an efficient government that can quarantine if need be.

But time-honoured methods still carry their weight in modern Mexico. That was clear on Sunday with the procession of Our Father Jesus of Health, and with the novena – usually a nine-day-long series of prayers – to Our Lady of Guadalupe being organized by the Archdiocese of Mexico City for the coming days.

“You who have rescued us from other plagues, entrust us to the mercy of He who healed us with His wounds and freed us from death with His Resurrection,” the devout are praying, at the request of Mexico’s Primate Cardinal Norberto Rivera.

On Sunday, most churches in the Mexican capital had cancelled all community masses until further notice, following last minute orders from church authorities. In the coming days, there will be no communal, large-scale first communions or confirmations and no large wedding masses.

When it comes to faith, something has changed with respect to the plagues of old. Earlier, churches would fill up to pray at times of epidemics, said Archdiocese spokesman Hugo Valdemar, whereas now – in the face of scientific progress – people know that concentrating in closed spaces can be worse. Viruses pass from person to person even in God’s house.

Some onlookers were incredulous late Sunday as the procession carrying Our Father Jesus of Health – a figure of Christ on the cross that had not been carried through the streets since 1850 – advanced, carried by men with blue face masks.

“That won’t do any good,” one person muttered.

However, Valdemar disagreed.

“It is a centenary tradition to take out Our Father Jesus of Health on people’s shoulders when a pest or epidemic attacks the population,” he noted.

Mexico has one of the largest numbers of Roman Catholic faithful in the world, second only to Brazil. Religion has deep roots among the population, particularly with the adoration of Our Lady of Guadalupe.

The Guadalupe basilica, which usually hosts many thousands of faithful every Sunday, is now holding masses only behind closed doors.

Cardinal Rivera invited all Catholics to pray at home, follow mass on the radio and on television and take part in the novena of prayer.

The goal is to ask the Virgin Mary “to free the city and the country from this threat that is hanging on their residents, as she prodigiously did in the past, especially in the pests that the same city suffered in the years 1554, 1695, 1736 and 1850.” (dpa)

Monkey menace, a poll issue in Shimla

Shimla, Apr 9 (ANI): The general elections approaching, the monkey menace in Shimla has become a major poll issue.

Among the worst hit areas are Hamirpur, Sirmour, Solan, Kangra, Mandi andhimla districts covering almost all four parliamentary seats of Himachalradesh.

Most of the farmers grow fruits and crops such as maize and wheat. But monkeys are destroying the crop. They want to elect a candidate who can assure them riddance from the monkeys.

As a farmer, Shyamlal from Pantegli village said, “The monkeys destroy whatever we sow in the fields. The monkeys are shifting from the city to the villages. We used to sow maize but that was completely destroyed by the monkeys.”

The farmers believe that the politicians promise to find a permanent solution to the monkey problem during elections, only to forget afterward.

In the 11th Assembly elections too, farmers had made it a poll issue. After the elections, the State Government tried to open Primate Protection Parks but these proved to be a complete failure.

Sterilization of the monkeys is a solution but not much has been done in this regard.

“As per the Wildlife Institution of India, until 70 per cent of any species is sterilized, the population of the species cannot be controlled. But over the years, the BJP and the Congress Governments are saying that they will establish sterilization centres in Shimla, Una and Hamirpur districts to curb the monkey menace and spend 20 million for the purpose. But till today, all they could do was sterilize 4000 monkeys and that too of all age groups,” said Kuldeep Tanvar, a social worker and a Communist party of India leader.

An amendment in the Wildlife Protection Act is needed to tackle the problem. There is also a need to reintroduce the export policy, for exporting monkeys for biomedical research, which was in practice before 1978. By Hemant Chauhan (ANI)

Hunters begin search for Russian Yeti

London, Feb 19 (ANI): Hunters are tracking a family of Yetis after reports that the creatures are living in a mountain cave complex in a Russian town.

According to a report in the Daily Star, sightings have been made near the remote Russian mining town of Tashtagol in Siberia.

The animals are said to be more than 6ft tall with ginger-black hair and leave large, distinctive footprints that include toe marks.

“There have been reports over the years about these creatures, but the number has increased dramatically,” said Galina Pustogacheva, spokesman for the town. “We have had more than 10 sightings in recent weeks,” she added.

The creatures have been seen walking on two legs by villagers from the hamlets of Elbeza and Kabarza and tourists visiting the region around the Azass caves on Mount Shoriya.

Sightings have worried locals and forced officials to launch an expedition, led by hunters and anthropologists.

“People here are scared the creatures will attack villages because of hunger,” said Nikita Shulbayev, deputy head of the local administration.

“We made a decision to send an expedition to research this issue. We need to understand whether they are dangerous for people. We need to calm people down,” she added.

“Scientists from Kemerovo University will help us discover what the creatures are – whether they are a rare kind of bear or a surviving primate from pre-historic times,” she informed.

No photographs have been taken of the beasts.

But, according to one witness, “The creature reminds me of a bear. In his footprints, one can clearly see toes. He is 1.5 to two metres high. He is covered with red and black hair and can climb trees.” (ANI)

Apes’ faces ‘reveal family ties’

London, Feb 12 (ANI): Humans can discern family resemblances in great apes and some monkeys, hints a new study.

According to lead researcher Alexandra Alvergne, an anthropologist at the University of Montpelier, France, if humans can garner enough information from primate faces to tell kin from stranger, then perhaps closely related animals can do the same.

“We do not know if the others species use [facial recognition], but we know that it is possible,” New Scientist quoted her, as saying.

The finding could shed light how, among promiscuous species such as chimpanzees, fathers determine which children are their own.

Facial recognition might also help closely related individuals avoid inbreeding, Alvergne says.

To see if other primate faces convey enough information to determine relatedness, the scientists tested whether humans could see a family resemblance in chimpanzees, lowland mountain gorillas, mandrills and chacma baboons.

The research team showed volunteers – 618 in all – a picture of one individual, followed by three different members of the same species. One of the three was the parent of the first animal.

On average, volunteers picked the related chimpanzee, gorilla and mandrill at rates well above chance, but not so for baboons. This could be because baboon faces convey few obvious giveaways to kinship.

The study has been published in the International Journal of Primatology. (ANI)

Ancestral genome of apes and humans had burst of DNA sequence duplication

Washington, Feb 12 (ANI): A new study has suggested that the genome of the evolutionary ancestor of humans and present-day apes underwent a burst of activity in duplicating segments of DNA.

“The new study shows big differences in the genomes of humans and great apes within duplicated sequences containing rapidly evolving genes. Most of these differences occurred at a time just prior to the speciation of chimpanzees, gorillas, and humans,” said University of Washington (UW) researchers Tomas Marques-Bonet and Jeffrey M. Kidd who headed the study.

“It is unclear why, but the common ancestor of humans, chimps and gorillas had an unusual activity of duplication,” said Kidd. “Moreover, we don’t yet know the functions of most of the genes that were affected by these duplications,” he added.

The great ape ancestors, from whom humans, gorillas and chimps descended, lived in Africa between 8 million and 12 million years ago.

Most scientists think that the lineage that eventually led to chimps and humans diverged from the African great ape ancestors about 5 million to 7 million years ago.

“What’s exciting for us to learn was that sequence duplication acceleration occurred in an era when other types of mutations had slowed within the hominid (human-like) lineage,” said Evan Eichler, UW professor of genome sciences.

“There was significant increase in genome activity in both the number of duplication events and the number of base pairs of DNA that were affected,” Marques-Bonet noted.

The results suggest that evolutionary properties of copy-number mutations, such as repeated segments, differ from other forms of mutations.

To understand the pattern and rate of genomic duplication during evolution, the researchers constructed a map of segmental duplications for four primate genomes: macaque, orangutan, chimpanzee, and human.

They then compared the duplications across the four species. They characterized a duplication as shared if it occurred in two or more of the four species and lineage-specific if it was found in just one species.

A small fraction of the duplicated content was human-specific, while the major part of duplications was shared with the other species.

According to the researchers, “Our team found striking examples of recurrent duplications of DNA segments that happened independently in different lineages.”

“Most of the shared duplications were already present in the chimp-human common ancestor, but these are highly variable in copy number between and within human and great ape species,” they added. (ANI)