Genes linked to spinal disc degeneration identified

Washington, Mar 13 (ANI): Researchers from University of Alberta have identified certain genes responsible for spinal disc degeneration.

Michele Crites-Battie and Tapio Videman, in the Faculty of Rehabilitation Medicine, have discovered eight genes linked to lumbar disc degeneration.

“We found more genes associated with disc degeneration than was discovered in 30 prior studies. This is very exciting,” said Videman.uring the study, the researchers looked at 25 specific genes they thought could be linked to the disease and narrowed their search down using state-of-the-art DNA analysers.

“Identifying genes involved can provide important insights into the biological mechanisms behind disc degeneration and a better understanding of what is going wrong in the system,” said Crites-Battie.

“This can eventually lead to effective interventions for the problem,” she added.

The pair will conduct further studies to look at the interaction between these eight genes and their environment. This will help them identify what gene forms indicate susceptibility.

“This will tell us who should avoid physical loading, and in which people obesity could be a risk factor for spine problems,” said Videman.

This could be a long process as disc degeneration is what’s called polygenic, meaning it involves more than one gene.

“There are likely to be quite a number of genes involved and a system of complex gene-gene and gene-environment interactions,” said Crites-Battie.

“Obtaining a full appreciation of the genetic architecture of disc degeneration is likely to be a very lengthy, involved process,” she added. (ANI)

Hong Kong sex photos scandal pop star to testify in Canadian court

Hong Kong – The Hong Kong pop star at the centre of a sex photos scandal is to testify against the man accused of downloading pictures from his computer in Canada, a news report said Wednesday.

Edison Chen, 28, has refused to return to Hong Kong for court proceedings surrounding the pictures showing him with a string of naked young starlets that circulated on the internet early last year.

A deal has now been reached for Chen to give evidence instead at a five-day hearing in the Supreme Court of British Columbia on February 23, the South China Morning Post reported.

The case caused an international sensation and the pictures, allegedly stolen from Chen’s laptop when he took it in for repairs, were viewed by millions of fans in Hong Kong, China and Taiwan.

Chen’s refusal to return to Hong Kong has stalled the trial of computer technician Sze Ho-chun, 23, accused of distributing the photos of Chen performing sex acts with well-known starlets.

Sze, who will not appear at the hearing in Canada, has pleaded not guilty to three counts of obtaining access to a computer with a view to making a dishonest gain.

He will go on trial in Hong Kong in April, the newspaper reported, and Chen’s testimony from the Canadian court hearing will be presented as part of the prosecution case.

Chen, who was forced to apologize to the starlets and announce his retirement from showbiz, was named one of Hong Kong’s People of 2008 in a radio poll last week. (dpa)

Ten extinct beasts that could walk the Earth again

London, Jan 8 (ANI): A report in New Scientist has predicted ten extinct creatures that might be brought back to life.

On the assumption that necessary technology to re-create extinct life would soon be available, the selected ten animals are:

Sabre-toothed tiger: There are some spectacularly preserved sabre-toothed specimens from the La Brea tar pits in Los Angeles. There are also some permafrost-preserved specimens that might be a better source of DNA.

Neanderthal: A draft sequence of the Neanderthal genome should be published sometime this year. There is speculation that it could be used to resurrect the Neanderthal. Because of our very close-shared ancestry, humans would make ideal egg donors and surrogate mothers.

Short-faced bear: Recovering the DNA of the short-faced bear should be possible as there are specimens encased in permafrost.

Tasmanian tiger: The existence of various preserved tissues less than a century old means geneticists should be able to get good-quality DNA and produce a complete sequence of the Tasmanian tiger genome before too long.

Glyptodon: The Volkswagen Beetle-sized “colossal” armadillo, with its spiky, club-like tail, once rumbled across the South American countryside. Because there are no frozen glyptodons, obtaining usable DNA will depend on finding well-preserved remains in a cool, dry cave.

Woolly rhinoceros: Resurrecting the woolly rhino has lots going for it. As with the mammoth, there are plenty of specimens preserved in permafrost, and the availability of hair, horns and hooves is a big plus.

Dodo: In 2002, geneticists at the University of Oxford got permission to cut into the world’s best-preserved dodo specimen, a foot bone, complete with skin and feathers. This yielded minute fragments of dodo mitochondrial DNA but nothing more. Since then, no other specimen has yielded even a whiff of dodo DNA, but there is still hope that some will one day be found.

Giant ground sloth: The sloth’s relatively recent extinction means that several specimens have been found with hair, an excellent source of DNA.

Moa: There is plenty of moa DNA to be found in well-preserved bones and even eggs in caves across New Zealand, so obtaining a moa genome should be doable.

Irish elk: This Pleistocene giant was once found across Europe. A typical male of the species stood more than 2 metres tall at the shoulder and sported antlers 4 metres wide. It is actually a deer rather than an elk, and its closest living relative is the much smaller fallow deer.

Gorilla: Conservationists are freezing tissue samples from some threatened species of Gorilla, so clones could be created with the help of a closely related surrogate species if a suitable habitat becomes available. (ANI)

India, Malaysia sign pact on employing labourers

New Delhi, Jan.3 (ANI): India and Malaysia on Saturday signed a Memorandum of Understanding (MoU) for improving recruitment and working condition of employees.

Indian Overseas Affairs Minister Vayalar Ravi and the Malaysian Human Resources Minister Dato Dr. S. Subramaniam signed the MoU in New Delhi.

“It is a major milestone in our friendship mark towards the protection of Indian workers going abroad and of course it will further strengthen relation between Malaysia and India,” said Ravi.

The broad procedure for employment of workers and the responsibilities of employees, workers and recruitment agencies are outlined in the agreement.

With the signing of MoU both the nations have agreed to facilitate orderly recruitment and deployment of workers.

The two governments will work together on pre-departure orientation and upgrading of skills.

They have also agreed for protection and welfare of all categories of workers under the labour and other laws of the host country.

A joint working group (JWG) would be set up to implement the MoU and review employment opportunities and availability of corresponding skills in both countries.

“This joint committee will work out the administrative details of how are we are going to implement the spirit of intentions of this memorandum of understanding.  Hope with this we will have a sufficiently strong legal framework to ensure such recruitment is done in ordinary manner and any problems which might arise could be resolved on the basis of suitable systems and mechanics which will be set up by the joint committee,” said Subramaniam.

The group will also explore new avenues for cooperation in the field of labour and manpower development for mutual benefit.

The JWG consisting of at least three members from each Government will meet twice a year, alternatively in India and Malaysia.

Malaysia is an important destination for Indian workers. According to official estimates of the Malaysian Government, there are approximately 150,000 Indian workers in Malaysia, out of about 2 million foreign workers there.

Most of the Indian workers work in the plantation and construction sectors. During 2007, about 30,916 workers immigrated to Malaysia after obtaining emigration clearance.(ANI)

India, Malaysia sign agreement on employment of workers

New Delhi, Jan 3 (ANI): India and Malaysia today signed an agreement for improvement of conditions of recruitment and employment of their workers in each other”s country.

The MOU was signed by the Overseas Indian Affairs Minister Vayalar Ravi and the Malaysian Human Resources Minister Dato Dr. S. Subramaniam in New Delhi.

The agreement sets out the broad procedure for employment of workers and outlines the responsibilities of employees, workers and recruitment agencies.

India and Malaysia agreed to facilitate employment of workers between the two countries and promote orderly recruitment and deployment of workers.

The two governments will work together on pre-departure orientation and skill up gradation training. They have also agreed for protection and welfare of all categories of workers under the labour and other laws of the host country.

The two countries will constitute a Joint Working Group to implement the MOU and review employment opportunities and availability of corresponding skills in both countries.

The Group will also explore new avenues for co-operation in the field of labour and manpower development for mutual benefit.

The Joint Working Group consisting of at least three members from each Government will meet twice a year, alternatively in India and Malaysia.

Malaysia is an important destination for Indian workers. According to official estimates of the Malaysian Government, there are approximately 1.5 lakhs Indian workers in Malaysia, out of about two million foreign workers there.

Most of the Indian workers work in the plantation and construction sectors. During 2007, about 30,916 workers emigrated to Malaysia on ECR passports after obtaining emigration clearance from the Protector of Emigrants.

During the 4th Joint Commission Meeting between India and Malaysia, which was held on February 23-24, 2007 at New Delhi, the draft MoU was discussed and subsequently, the Malaysian side had handed over a counter Draft.

Formal negotiations on the draft MoU were held between the official delegations of both countries at Kuala Lumpur on June 28, 2007.

The negotiations culminated in finalization and initialing of the MoU. The Cabinet approved signing the MoU on March 20, 2008. (ANI)