Nerve pain pill found effective in treating hot flashes

Washington, May 16 (ANI): A pill used to treat nerve pain has been found effective in treating hot flashes in women, claim Mayo Clinic researchers.

They have found that pregabalin decreased hot flash severity and frequency about 20 percent more than did a placebo.

Pregabalin has been found to offer about the same benefit as gabapentin, an older, related drug, as well as newer classes of antidepressants.

“Hot flashes are a major problem in many women, and for those who opt not to take hormonal therapies or antidepressants, pregabalin appears to be another treatment option,” said the study’s lead author, Charles Loprinzi, M.D., a medical oncologist at the Mayo Clinic in Minnesota.

Women who use pregabalin only need to take two pills a day, versus three for gabapentin, he added.

Gabapentin and a variety of antidepressants are commonly prescribed for treatment of hot flashes and pregabalin is a newer version of gabapentin.

Dr. Loprinzi and colleagues set up a 207-participant study conducted by the North Central Cancer Treatment Group (NCCTG). Patients getting pregabalin started off with lower doses which were increased weekly to the eventual full dose.

The researchers found that for the 163 patients both doses of pregabalin reduced hot flashes to about the same degree, but that toxicities, such as cognitive dysfunction, were increased at the higher dose.

After six weeks of treatment, women receiving pregabalin showed 65 percent decrease in hot flashes compared to 50 percent decrease in those receiving placebo.

“All in all, this study demonstrates that we have another agent to add to the list of medications that offer benefit against hot flashes, even in women using anti-estrogen therapies,” said Dr. Loprinzi .

The findings were presented at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO). (ANI)

Re-polling at 35 booths in Bihar, West Bengal, Sikkim and Gujarat begins

New Delhi, May 4 (ANI): Re-polling at 35 booths in Bihar, West Bengal, Sikkim and Gujarat began this morning.

The Election Commission has ordered re-polling following irregularities during the third phase of Lok Sabha polls last Thursday.

Last Thursday, polling took place for all the 26 Lok Sabha seats of Gujarat. Besides Gujarat, polling was also held in 14 seats in West Bengal, 11 in Bihar, 10 in Maharashtra and one in Sikkim.
The Commission has also ordered re-polling at four booths in Mumbai North Central Parliamentary constituency.

Campaigning for the fourth phase ends on Tuesday. (ANI)

Priya Dutt files nomination papers in North Central Mumbai

Mumbai, Apr 8 (ANI): Congress candidate Priya Dutt today filed her nomination papers from the North-Central constituency of Mumbai.

Daughter of late actor-turned-politician Sunil Dutt was accompanied with large supporters, who reached the Bandra Collector Office to file the papers.

On Monday, she failed to file her nomination papers as she was stuck in traffic jam.

Priya is contesting against Bharatiya Janata Party (BJP) candidate Mahesh Jethmalani.

She won the Mumbai North-Central parliamentary constituency in 2004. (ANI)

Priya Dutt visits Siddhivinayak Temple ahead of filing nomination

Mumbai, Apr. 6 (ANI): Congress leader Priya Dutt stopped over at the Siddhivinayak Temple in Mumbai today ahead of filing her nominations for the North Central Mumbai constituency.

She won the same seat in 2004.

On Sunday, Priya’s brother Sanjay Dutt refused to campaign for her as he had prior commitments with the Samajwadi Party in Lucknow.

Sanjay Dutt is the SP General Secretary.

Priya Dutt is contesting against lawyer Mahesh Jethmalani of the BJP. (ANI)

‘Will seek votes on basis of UPA govt performance’

After piquing his adversaries within the party for the nomination from the South Central Mumbai constituency, Congress MP from North Central Mumbai Eknath Gaikwad is now gearing up for a contest against Mahim MLA Suresh Gambhir of the Shiv Sena.

Gaikwad, 69, had won a surprise victory in 2004 against Lok Sabha Speaker Manohar Joshi of the Shiv Sena.

The former three-term MLA from Dharavi is planning to contest for his second innings in a constituency that has seen its name and boundaries being changed in the delimitation. The following are excerpts from an interview:

What will be your poll plank? My main plank will be the performance of the Congress-led UPA Government at the Centre in the last five years and the manifesto of the Congress Party. My work as an MP, public contacts, relations with people and my work aimed at redressal of public grievances will also be important.

Mumbai East MP Gurudas Kamat was also in the race for your constituency. Do you see any threat from your rivals within the party? I do not feel that such an atmosphere exists. I have been moving around in Chembur and Anushakti Nagar (earlier part of Kamat’s constituency) for the past two days and meeting MLAs and corporators. I cannot sense any discrimination. Gurudas (Kamat) also belongs to the Congress. In a democracy, all feel that they must get a nomination and nothing will happen once my nomination has been declared by Sonia Gandhi and the high command. I am also organising a conclave of workers at Sion where Gurudas will also be present.

Sena candidate Gambhir has pockets of support even among minority voters, apart from the significant number of Maharashtrians. Do you see a strong threat from the Shiv Sena? This will not be of any trouble. Gambhir was elected an MLA with a margin of just over 2,000 votes, and the Congress candidate came number two. Of the seven MLAs in the constituency, five belong to the Congress and two to the Sena. This election is for power at the Centre and is being fought on the policies of the party. My contacts with people will also help. If the constituency was so easy for the Sena, Manohar Joshi would have contested here. However, I am not underestimating Suresh Gambhir.

Your constituency of North Central Mumbai was seen to be jinxed for people who were trying to get re-elected. Barring Sharad Dighe of the Shiv Sena who was elected in 1984 and 1991, the constituency has a record of seeing sitting MPs biting the dust. I have been elected since 1985 from Dharavi. Before I was elected, it was said no one could be elected twice from the constituency. I have won thrice and my daughter (Varsha Gaikwad) has been elected once. We are people who make history.

There is resentment in your stronghold of Dharavi over the arbitrary method in which the Dharavi redevelopment has been initiated. Do you expect a backlash? There is no reason for the people to be cross. Some (Sena) tried to mislead them by asking for 400-sq ft houses, but Dharavi is a difficult slum and giving 400-sq ft houses is not possible owing to the density of population. People have realised the double standards (of the Sena). They (Sena) are also not seeking 400-sq ft houses in the SRA projects that are underway as the work has been undertaken by their builders. We have promised 300-sq ft carpet area houses. If we wanted to cheat them, we could have promised 400 to 450-sq ft super carpet area houses, but we told the truth. I will also get votes from areas like Dadar and Prabhadevi as I have taken up problems of the old buildings. I expect more votes than last time from these areas as earlier Manohar Joshi was in the fray and they had no option. Now they have an option.

What will be the impact of the MNS? The MNS will eat into the Sena votes. I will not be surprised to get a lead in the Dadar Mahim constituency owing to it.

Gawli joins hands with BSP

Mumbai, Feb 27 (ANI): Former mafia don and Maharashtra legislator Arun Gawli’s party-Akhil Bharatiya Sena (ABS) on Friday joined hands with the Bahujan Samaj Party (BSP).

Gawli will contest the Mumbai North Central Lok Sabha seat on a BSP ticket.

“The ABS chief has already given a letter of consent to merge the two parties,” BSP state president Vilas Garud said.

Congress’s Eknath Gaekwad is presently representing the constituency.

Gawli was elected to the assembly from a south Mumbai constituency, Chinchpokli, in 2004. He was sent to custody in September last year in connection with an extortion case. (ANI)

Japanese volcano erupts, spews smoke 2,000 metres in air

Japanese volcano erupts, spews smoke 2,000 metres in air Tokyo – The volcano Mount Asama in north-central Japan erupted Monday, spewing smoke 2,000 metres above its crater and sending ash as far away as Tokyo, the Japan Meteorological Agency said.

The agency issued a warning of continued large ash deposits in the surrounding 4-kilometre area. No casualties were reported.

The volcano erupted at 1:51 am (1651 GMT Sunday), and volcanic smoke was detected until around 8 am.

A thin layer of ash fell on rooftops and car windows in Tokyo’s Tachikawa city, about 100 kilometres south-east of Mount Asama.

The agency said volcanic activity had subsided and the frequency of the volcanic earthquakes had decreased.

The 2,568-metre Mount Asama, on the border between Gunma and Nagano prefectures, last erupted in August.

In southern Japan, several minor volcanic eruptions also had been detected since Sunday on Sakurajima island, south of Kagoshima prefecture, the Fukuoka District Meteorological Observatory said.

The observatory raised the alert level because it said it expected debris could reach surrounding areas within a 2-kilometre radius of the 1,117-metre Sakurajima volcano and volcanic activity might increase. (dpa)

Japanese volcano erupts, smoke reaches 2,000 metres

Japanese volcano erupts, smoke reaches 2,000 metres Tokyo – Mount Asama in north-central Japan erupted early Monday, spewing volcanic ashes to an altitude of 2,000 metres, the Japan Meteorological Agency said.

The agency issued a warning of continued large ash deposits in the surrounding 4-kilometre radius. No casualties have been reported.

The mountain erupted at about 1:51 am from the crater, and volcanic smoke was detected until around 8 am.

Mount Asama, on the border between Gunma and Nagano provinces, erupted in August. (dpa)