General strike curbs Manipur’s normal life

Imphal, Sep 12 (ANI): Normal life has been curbed in Manipur on Saturday due to a 24 hours general strike called by the Joint Action Committee (JAC) to protest against the alleged fake encounters.

The JAC is a group of NGOs, protesting the recent killing of a driver in an encounter.

The markets, shops, and business establishments in most parts of the state remained closed.

The transport services within the state and also with the neighboring states have been affected due to the strike.

A driver named Md Rehaman alias Tomba was killed along with five others, in an encounter with the security forces on September 8 at Awang Khul in Imphal West district.

The security forces maintain that the youths who were killed in the encounter were militants.

The All Manipur Rickshaw Drivers and Pullers Association (AMRDPA), said that Rehaman, who was member of the organization, was use to ferry passengers from Imphal to Moreh town from last 15 years. (ANI)

Signalling pathway operational in intra-abdominal fat identified

Washington, July 15 (ANI): Ben-Gurion University of the Negev (BGU) researchers and Germany-based University of Leipzig experts have announced the identification of a signalling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.

“Fat tissue in obesity is dysfunctional, yet, the processes that cause fat tissue to malfunction are poorly understood-specifically, it is unknown how fat cells ‘translate’ stresses in obesity into dysfunction,” said Dr. Assaf Rudich, senior lecturer from the Department of Clinical Biochemistry at Ben-Gurion University.

Fat tissue is no longer considered simply a storage place for excess calories, but in fact is an active tissue that secretes multiple compounds, thereby communicating with other tissues, including the liver, muscles, pancreas and the brain.

Normal communication is needed for optimal metabolism and weight regulation, but in obesity, fat (adipose) tissue becomes dysfunctional, and mis-communicates with the other tissues.

According to the researchers, this places fat tissue at a central junction in mechanisms leading to common diseases attributed to obesity, like type 2 diabetes and cardiovascular diseases.

The researchers highlight the fact that fat tissue dysfunction is believed to be caused by obesity-induced fat tissue stress: Cells over-grow as they store increasing amounts of fat. They say that this excessive cell growth may cause decreased oxygen delivery into the tissue; individual cells may die (at least in mouse models), and fat tissue inflammation ensues.

Excess nutrients, they add, may also lead to increased metabolic demands, and cause cellular stress.

The BGU and Leipzig teams collected fat tissue samples from people undergoing abdominal surgery, and identified a signalling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.

They say that the degree of activation of a signalling pathway from these individuals was compared with those of leaner people, those with obesity predominantly characterized by accumulation of “peripheral” fat, and those with obesity with predominant accumulation of fat within the abdominal cavity.

They found that the signalling pathway was more active depending on the amount of fat accumulation in the abdomen, and that it correlated with multiple biochemical markers for increased cardio-metabolic risk.

In their study report, they have revealed that the expression of one of the upstream signaling components, a protein called ASK1, predicts whole-body insulin resistance (an endocrine abnormality that is strongly tied to diabetes and cardiovascular disease), independent of other traditional risk factors.

The researchers have also shown that although non-fat cells within adipose tissue express most of this protein in lean persons, the adipocytes themselves increase its expression by more than four-fold in abdominally-obese persons.

“The importance of this study is not only in contributing to the understanding of adipose tissue dysfunction in obesity, but as a consequence, may provide important leads for novel ways to prevent the dangerous consequences, such as type 2 diabetes, of intra-abdominal fat accumulation,” states Dr. Iris Shai, a BGU researcher at the S. Daniel Abraham International Center for Health and Nutrition and Soroka University Medical Center in Beer-Sheva, Israel.

The study has been published in the Endocrine Society’s the Journal of Clinical Endocrinology and Metabolism. (ANI)

Two Chinese writers pen ‘instant biography’ of Michael Jackson

New Delhi, July 6 (ANI): Two Chinese writers worked continuously for 48 hours to produce an “instant biography” of late King of Pop Michael Jackson.

The 130,000-word book, titled ‘Moonwalk in Paradise’, has been written by Jiang Xiaoyu and Xing Han, and published by Chinese publishing house Xiandai.

A story published by the China Youth Daily suggests that the two writers, who have never met Jackson, have simply written the story from their “accumulated knowledge about the king of pop,” reports the China Daily.

“Though it is hard to tell how big the market for instant books is in China, I am sure we have done a nice job on quickly responding to market needs,” said Zang Yongqing, the general editor of Xiandai.

Jiang, who has written blogs and reviews about the pop icon, said that he hoped his book would help Chinese fans find a better way to relieve their pain.

“I am not only a music critic but also a fan of the King of Pop, so I understand what fans really need,” he said.

However, Zhao Xin, a PhD student of literature at Beijing Normal University, said that “authenticity and accuracy” should be the cornerstones of a biography.

“The writers might infringe on copyright if they never had the chance to interact with the subject,” he said.

More than 10 Chinese publishing houses are also planning to launch instant books about Jackson. (ANI)

Mysore shutdown evokes mixed response

Mysore July 4 (ANI): A dawn to dusk shutdown call given by the Hindu Jagaran Vedike in protest against an attack on a Bharatiya Janata Party (BJP) youth leader evoked a mixed response here today.

Normal life was partially affected by the shutdown.

It may be recalled that a mob armed with weapons attacked Giridhar, the President of Mysore unit of the Bharatiya Janata Yuva Morcha (BJYM), and his friend Wajid on Friday evening. Giridhar is said to in critical condition at Mysore’s Apollo Hospital.

Police said that some persons have been arrested in connection with the attack.

Meanwhile, Karnataka’s Home Minister V.S.Acharya is visiting Mysore this evening to asses the situation and expected to visit the riot-hit areas. (ANI)

Maoist shutdown disrupts normal life in Medinipur

Medinipur (West Bengal), June 22 (ANI): Normal life was affected in Medinipur region of West Bengal, as vehicular traffic, shops, schools and colleges were all affected due to the 48-hour Bandh call given by the Maoists, as a mark of protest against the security forces’s action in Lalgarh.

“Maoists have called for the shutdown because of the atrocities on them and we read about it newspapers and saw it on televisions. As we wanted peace to prevail, we kept the shops and rest of the places shut,” said Ramesh Mukherjee, a local resident.

Police and allied para-military forces deputed by the central government had regained control of Lalgarh police station, which was captured by Maoist rebels in one of the most brazen attacks in recent years that sparked unease in state.

The Maoists had given a call for 48-hour shutdown in five states West Bengal, Chhattisgarh, Bihar, Orissa and Jharkhand, demanding the clampdown by security forces in Lalgarh be withdrawn. (ANI)

Civic body employees’ strike disrupts normal life in Uttarakhand

Dehradun, June 19 (ANI): Normal life has been badly disrupted following an indefinite strike by civic body employees, causing acute water shortage and leading to growing garbage dumps in various parts of Uttarakhand.
Tourists and local residents are bearing the brunt of the ongoing strike as there is acute water shortage and accumulation of garbage dumps in the city.

“We are facing lot of problems. Water comes in the morning and that too for one hour. After one hour it stops coming and the water pressure is also very less. We don’t get any water to drink. There is growing garbage dump and no cleanliness. Also, there is power shortage. What should we do in such condition?” said Sushma, a local resident in Dehradun.

Even the supply of drinking water bottles in the market has run out due to heavy demand.

On Thursday, striking employees gathered at Gandhi Park in Dehradun city and raised anti-government slogans.

The agitating employees demanded implementation of Sixth Pay Commission recommendations and pledged to continue the strike until their demands were met.

“Our demands are first, that there should be no disparity in the payments or salaries of employees and recommendations of sixth pay commission should be implemented. Second, daily wage workers and PTC workers should be regularised. Third, pension and other allowances of all civic body workers should be at par with the state employees. Fourth, appointment should be made for all vacant posts that are vacant for past several years,” said Bhupindar, State President of Local Bodies Association.

The employees belonged to Uttarakhand civic bodies Dehradun Municipal Corporation, Jal Sansthan, and Panchayats. (ANI)

Tight security for PM’s polling booth in Assam

Guwahati, Apr 22 (ANI): Authorities in Guwahati have beefed up security at a school where Prime Minister Dr. Manmohan Singh is expected to cast his vote in the second phase of Lok Sabha polls.

Singh along with his wife Gursharan Kaur are expected to cast their votes on Thursday.
Police officials said ordinary voters would not be put to trouble by the extra security for the Prime Minister.

“Normal checking will be carried out on PM’s arrival. The rest of the voters can also come here and vote. Normal arrangements will be put in place. No inconvenience will be caused to any voter. But every body will be checked,” said G P Singh, Inspector General of Police.
Students at the school said they were excited about the Prime Minister’s visit.

“We are very happy that the Prime Minister is coming here. We hope the voting goes on smoothly and everything has been cleaned here for the PM’s visit,” said Parag Sharma, a student.

Singh is officially a voter from Guwahati.
A powerful bomb blast in a crowded parking area killed four people in Guwahati in the first week of April, ahead of Singh’s visit to the state. olice suspected that the United Liberation Front of Asom (ULFA) was behind the blast. (ANI)

Rajkot has a “batsman” candidate

Rajkot/Jaipur, Apr 21 (ANI): Mukund Dudhatra, an independent candidate from Rajkot, has captured the imagination of the residents by campaigning as a cricket batsman.

Infact the Election Commission has given him a symbol of a “batsman” so he dresses himself like an Indian cricketer and comes out on roads and streets padded up with bat in his hand and helmet on his head.

Dudhatra has also declared his asset of nearly 1.25 crore rupees during nominations, but when it comes to contesting the election he has made sure that he campaigns alone without any pomp and show at a mere cost of 10,000 rupees.

He believes that cricket is considered a religion in the country, which attracts people from all walks of life. He hopes to garner votes especially from the youth who are enthralled with the sport.

“My election symbol is very influential for the youth as most of the candidates who stand for elections are above the age of 50 and will never accept such a symbol, ” he said.

Ganpat, a government employee in Rajkot too was surprised to see him campaign his way, but isn’t still sure to vote Dudhatra for his credibility.

“The Indian Premier League is coming up. We join him and show our enthusiasm-playing cricket with him. We will vote this time, but still not sure whom to vote,” said Ganpat.

Meanwhile, Bharatiya Janata Party supporters in Jaipur have decided to put up cartoon campaigns to influence voters.

The cartoon-centric remarks were apparently put to depict Rajasthan Chief Minister Ashok Gehlot in different postures aiming to highlight the failure of the Congress party.

Gehlot cartoons put up had shown Gehlot as a parrot chirping “corruption”. Also depicted, acting with vengeance against BJP leaders and also cutting ribbons from one place to other.

“People look at it very keenly. Normal hoardings or big hoardings do not create much impact like this on people. Through these cartoons people develop a curiosity in their minds and come from far places to actually watch it. The cartoonist has shown the governments real administration and their deeds and his opinion in a few words,” said

The BJP is trying to hard to attract parliamentary seats in Rajasthan after they lost to the Congress in the 2008 state elections. By Suresh Parekh/Lokendra Singh (ANI)

‘Burping’ astrophysical jets recreated by plasma experiment

London, Feb 21 (ANI): A plasma experiment by scientists has recreated jets of charged particles for the first time in a laboratory, which could shed light on the behaviour of ‘burping’ astrophysical jets from stars and galaxies.

Astrophysical jets are among the largest and most energetic objects in the universe.

The matter inside them travels at nearly the speed of light from colossal black holes at the centres of galaxies. Smaller jets spew at lower speeds from young stars surrounded by discs of gas and dust.

Theorists don’t know exactly how jets form, but they believe the particles inside them are accelerated by magnetic fields, which could be whipped up as matter rotates around a star or black hole.

But, the magnetic fields that seem to keep jets focused can also form kinks that can destabilize the beams, raising questions about how the jets can remain tightly focused over very long distances.

Jets are also clumpy and seem to throw out material in bursts.

“They’re very inhomogeneous with lots of blobs, and it’s very clear that the jet turns on and off,” said Eric Blackman, an astrophysicist at the University of Rochester.

The source of this episodic behaviour is not clear.

But now, according to a report in New Scientist, Blackman and colleagues, led by plasma physicist Andrea Ciardi of the Ecole Normal Superieure in Paris, have recreated the intermittent behaviour that seems to create the clumps seen in telescopes.

“This is the first time we can actually produce episodic behaviour. The experiment shows jets can propagate very far, but they can be quite unstable at the source,” Ciardi told New Scientist.

To create a sequence of bursts, Andrea Ciardi and colleagues fed more than 100 billion watts of power into electrodes connected by a sheet of aluminium foil.

The current created a coiled magnetic field above the foil. It also burned a hole in the foil, turning the aluminium into a soup of charged particles called a plasma.

Because charged particles are accelerated in the presence of a magnetic field, the plasma then sped through the magnetic loop at hundreds of kilometres per second – comparable to speeds seen in stellar jets.

As the first jet was propelled away, more aluminum plasma that had burned off the foil moved in to take its place, and a new jet formed.

The team found that the magnetic environment left over from previous jets seems to stabilize and focus the next jet.

The flows that can be modelled by computer tend to be slow and cool.

Pudritz notes that experiments like this one can get a bit closer to simulating extreme astrophysical conditions, where it is not possible to measure the configuration of magnetic fields. (ANI)

‘Burping’ astrophysical jets recreated by plasma experiment

London, Feb 21 (ANI): A plasma experiment by scientists has recreated jets of charged particles for the first time in a laboratory, which could shed light on the behaviour of ‘burping’ astrophysical jets from stars and galaxies.

Astrophysical jets are among the largest and most energetic objects in the universe.

The matter inside them travels at nearly the speed of light from colossal black holes at the centres of galaxies. Smaller jets spew at lower speeds from young stars surrounded by discs of gas and dust.

Theorists don’t know exactly how jets form, but they believe the particles inside them are accelerated by magnetic fields, which could be whipped up as matter rotates around a star or black hole.

But, the magnetic fields that seem to keep jets focused can also form kinks that can destabilize the beams, raising questions about how the jets can remain tightly focused over very long distances.

Jets are also clumpy and seem to throw out material in bursts.

“They’re very inhomogeneous with lots of blobs, and it’s very clear that the jet turns on and off,” said Eric Blackman, an astrophysicist at the University of Rochester.

The source of this episodic behaviour is not clear.

But now, according to a report in New Scientist, Blackman and colleagues, led by plasma physicist Andrea Ciardi of the Ecole Normal Superieure in Paris, have recreated the intermittent behaviour that seems to create the clumps seen in telescopes.

“This is the first time we can actually produce episodic behaviour. The experiment shows jets can propagate very far, but they can be quite unstable at the source,” Ciardi told New Scientist.

To create a sequence of bursts, Andrea Ciardi and colleagues fed more than 100 billion watts of power into electrodes connected by a sheet of aluminium foil.

The current created a coiled magnetic field above the foil. It also burned a hole in the foil, turning the aluminium into a soup of charged particles called a plasma.

Because charged particles are accelerated in the presence of a magnetic field, the plasma then sped through the magnetic loop at hundreds of kilometres per second – comparable to speeds seen in stellar jets.

As the first jet was propelled away, more aluminum plasma that had burned off the foil moved in to take its place, and a new jet formed.

The team found that the magnetic environment left over from previous jets seems to stabilize and focus the next jet.

The flows that can be modelled by computer tend to be slow and cool.

Pudritz notes that experiments like this one can get a bit closer to simulating extreme astrophysical conditions, where it is not possible to measure the configuration of magnetic fields. (ANI)

‘Burping’ astrophysical jets recreated by plasma experiment

London, Feb 21 (ANI): A plasma experiment by scientists has recreated jets of charged particles for the first time in a laboratory, which could shed light on the behaviour of ‘burping’ astrophysical jets from stars and galaxies.

Astrophysical jets are among the largest and most energetic objects in the universe.

The matter inside them travels at nearly the speed of light from colossal black holes at the centres of galaxies. Smaller jets spew at lower speeds from young stars surrounded by discs of gas and dust.

Theorists don’t know exactly how jets form, but they believe the particles inside them are accelerated by magnetic fields, which could be whipped up as matter rotates around a star or black hole.

But, the magnetic fields that seem to keep jets focused can also form kinks that can destabilize the beams, raising questions about how the jets can remain tightly focused over very long distances.

Jets are also clumpy and seem to throw out material in bursts.

“They’re very inhomogeneous with lots of blobs, and it’s very clear that the jet turns on and off,” said Eric Blackman, an astrophysicist at the University of Rochester.

The source of this episodic behaviour is not clear.

But now, according to a report in New Scientist, Blackman and colleagues, led by plasma physicist Andrea Ciardi of the Ecole Normal Superieure in Paris, have recreated the intermittent behaviour that seems to create the clumps seen in telescopes.

“This is the first time we can actually produce episodic behaviour. The experiment shows jets can propagate very far, but they can be quite unstable at the source,” Ciardi told New Scientist.

To create a sequence of bursts, Andrea Ciardi and colleagues fed more than 100 billion watts of power into electrodes connected by a sheet of aluminium foil.

The current created a coiled magnetic field above the foil. It also burned a hole in the foil, turning the aluminium into a soup of charged particles called a plasma.

Because charged particles are accelerated in the presence of a magnetic field, the plasma then sped through the magnetic loop at hundreds of kilometres per second – comparable to speeds seen in stellar jets.

As the first jet was propelled away, more aluminum plasma that had burned off the foil moved in to take its place, and a new jet formed.

The team found that the magnetic environment left over from previous jets seems to stabilize and focus the next jet.

The flows that can be modelled by computer tend to be slow and cool.

Pudritz notes that experiments like this one can get a bit closer to simulating extreme astrophysical conditions, where it is not possible to measure the configuration of magnetic fields. (ANI)

‘Burping’ astrophysical jets recreated by plasma experiment

London, Feb 21 (ANI): A plasma experiment by scientists has recreated jets of charged particles for the first time in a laboratory, which could shed light on the behaviour of ‘burping’ astrophysical jets from stars and galaxies.

Astrophysical jets are among the largest and most energetic objects in the universe.

The matter inside them travels at nearly the speed of light from colossal black holes at the centres of galaxies. Smaller jets spew at lower speeds from young stars surrounded by discs of gas and dust.

Theorists don’t know exactly how jets form, but they believe the particles inside them are accelerated by magnetic fields, which could be whipped up as matter rotates around a star or black hole.

But, the magnetic fields that seem to keep jets focused can also form kinks that can destabilize the beams, raising questions about how the jets can remain tightly focused over very long distances.

Jets are also clumpy and seem to throw out material in bursts.

“They’re very inhomogeneous with lots of blobs, and it’s very clear that the jet turns on and off,” said Eric Blackman, an astrophysicist at the University of Rochester.

The source of this episodic behaviour is not clear.

But now, according to a report in New Scientist, Blackman and colleagues, led by plasma physicist Andrea Ciardi of the Ecole Normal Superieure in Paris, have recreated the intermittent behaviour that seems to create the clumps seen in telescopes.

“This is the first time we can actually produce episodic behaviour. The experiment shows jets can propagate very far, but they can be quite unstable at the source,” Ciardi told New Scientist.

To create a sequence of bursts, Andrea Ciardi and colleagues fed more than 100 billion watts of power into electrodes connected by a sheet of aluminium foil.

The current created a coiled magnetic field above the foil. It also burned a hole in the foil, turning the aluminium into a soup of charged particles called a plasma.

Because charged particles are accelerated in the presence of a magnetic field, the plasma then sped through the magnetic loop at hundreds of kilometres per second – comparable to speeds seen in stellar jets.

As the first jet was propelled away, more aluminum plasma that had burned off the foil moved in to take its place, and a new jet formed.

The team found that the magnetic environment left over from previous jets seems to stabilize and focus the next jet.

The flows that can be modelled by computer tend to be slow and cool.

Pudritz notes that experiments like this one can get a bit closer to simulating extreme astrophysical conditions, where it is not possible to measure the configuration of magnetic fields. (ANI)

‘Burping’ astrophysical jets recreated by plasma experiment

London, Feb 21 (ANI): A plasma experiment by scientists has recreated jets of charged particles for the first time in a laboratory, which could shed light on the behaviour of ‘burping’ astrophysical jets from stars and galaxies.

Astrophysical jets are among the largest and most energetic objects in the universe.

The matter inside them travels at nearly the speed of light from colossal black holes at the centres of galaxies. Smaller jets spew at lower speeds from young stars surrounded by discs of gas and dust.

Theorists don’t know exactly how jets form, but they believe the particles inside them are accelerated by magnetic fields, which could be whipped up as matter rotates around a star or black hole.

But, the magnetic fields that seem to keep jets focused can also form kinks that can destabilize the beams, raising questions about how the jets can remain tightly focused over very long distances.

Jets are also clumpy and seem to throw out material in bursts.

“They’re very inhomogeneous with lots of blobs, and it’s very clear that the jet turns on and off,” said Eric Blackman, an astrophysicist at the University of Rochester.

The source of this episodic behaviour is not clear.

But now, according to a report in New Scientist, Blackman and colleagues, led by plasma physicist Andrea Ciardi of the Ecole Normal Superieure in Paris, have recreated the intermittent behaviour that seems to create the clumps seen in telescopes.

“This is the first time we can actually produce episodic behaviour. The experiment shows jets can propagate very far, but they can be quite unstable at the source,” Ciardi told New Scientist.

To create a sequence of bursts, Andrea Ciardi and colleagues fed more than 100 billion watts of power into electrodes connected by a sheet of aluminium foil.

The current created a coiled magnetic field above the foil. It also burned a hole in the foil, turning the aluminium into a soup of charged particles called a plasma.

Because charged particles are accelerated in the presence of a magnetic field, the plasma then sped through the magnetic loop at hundreds of kilometres per second – comparable to speeds seen in stellar jets.

As the first jet was propelled away, more aluminum plasma that had burned off the foil moved in to take its place, and a new jet formed.

The team found that the magnetic environment left over from previous jets seems to stabilize and focus the next jet.

The flows that can be modelled by computer tend to be slow and cool.

Pudritz notes that experiments like this one can get a bit closer to simulating extreme astrophysical conditions, where it is not possible to measure the configuration of magnetic fields. (ANI)

King Khan recovering from surgery for a tear on his left shoulder muscle

King Khan recovering from surgery for a tear on his left shoulder muscle King Khan is finally recovering from surgery for a tear on his left shoulder muscle. He was operated yesterday after he returned from London. He was admitted to the Breach Candy Hospital in south Mumbai on Monday.

Shoulder specialist Dr Sanjay Desai, who performed the operation on the 43-year-old actor-producer said: “He resumed his normal diet and had a sound sleep. We have permitted him to go home.”

Dr. Desai further added, “The arthroscopic method of surgery, which was performed on the star, does not require opening of the entire joint. The surgery ensures less pain and minimal scar.”

Shah Rukh Khan had injured himself on the sets of “Dulha Mil gaya” in November last year. His doctors advised him last month to get the tear in the main muscle of his left shoulder fixed immediately. But he decided to undergo the operation after release of “Billu”.

Auto Credit May Bring Some Hope To The Wilting Auto Industry

Auto Credit May Brings Some Hope To The Wilting Auto IndustryLast month federal government announced, in its budget, the formation of the Canadian Secured Credit Facility under which Ottawa will purchase up to $12 billion in securities from financial institutions including banks.

The securities would be supported by loans and leases on vehicles and equipment. This would enable the automakers to offer financing to more consumers and dealers.

This news comes as the much needed relief to the automobile industry scorched by recession. But they seem to be getting much too impatient to wait till June.

“We need it today,” Bigland, chief executive officer of Chrysler Canada Inc., said in an interview at the Canadian International Auto Show. “It’s critical oxygen that the patient needs.”

“We can’t wait six months,” he said.

North America has witnessed a major slowdown on automobile sales due to the rising fuel prices, a subsequent global financial crisis that brought the credit markets to a standstill and wilting consumer confidence.

Bigland observed that in a normal economic climate, about 5 per cent of customers can’t get credit to buy vehicles, but Chrysler dealers across the country have given proof showing that level has shot up to 20 to 25 per cent in the past four months.

“It’s the number one issue affecting our business and it’s getting worse,” he said.

Bio-scientists, curators pool expertise to preserve world’s art, heritage

Washington, Feb 9 (IANS) Biotech scientists have teamed up with curators to stem the decay of world’s art and cultural heritage, hastened by the depredations of climate change.

Many of the world’s cultural treasures are created out of organic materials like paper, canvas, wood and leather which, in prolonged warmth and dampness, attract mould, micro-organisms and insects, causing decay and disintegration.

‘With the world financial crisis and the advent of climate change effects, there is a state of emergency at the museums of several tropical countries…,’ informed Alvaro Gonzalez, director, Venezuela’s Cultural Heritage Conservation Foundation, which is hosting the four-day UN affiliated event.

New biotechnology techniques that will be deliberated upon, include the use of micro-organisms to remove fungus and other problems on artwork, photos, documents, masonry and more.

‘The normal concern about single artefacts is no longer paramount. Storing and protecting entire collections safely has become a priority and scientists have a key role: developing techniques and procedures that are fundamental to heritage conservation,’ said Jose-Luis Ramirez, director of United Nations University’s Programme for Biotechnology for Latin America and the Caribbean (UNU-BIOLAC), an event sponsor.

Giancarlo Ranalli, professor at Universitá degli Studi del Molise in Pesche, Italy, for example, will describe his successful use of micro-organisms instead of chemicals to remove black crusts, nitrates, sulphates and other alterations from masonry, as well as unwanted animal glue from important painted frescos in Pisa and elsewhere in Italy subjected to well-intentioned but ill-advised restoration and preservation attempts in the 1980s.

His masonry restoration work has included the base of Michelangelo’s Pietà Rondanini and the Cathedrals of Milan and Matera.

Similarly, Sofía Borrego Alonso of the Archivo Nacional de la República de Cuba, said using costly chemical biocides to combat infestations of micro-organisms and insects, the principal agents of biodeterioration of cultural documents, not only harms the people that apply them, they accelerate the materials’ deterioration.

She will advocate the use of natural, plant-derived products successfully tested in Cuba’s National Archives.

Spanish researcher Nieves Valentin Rodrigo of the Instituto de Patrimonio Cultural de España, Madrid, takes the idea a step further, promoting the use of micro-organisms as bio-sensors to forewarn curators of potential risks to art objects from such threats as pollution and dust levels.

She said fungi and bacteria can be harnessed to warn of significant environmental fluctuations and the impact of too many visitors.

Besides biotechnologies, experts will revisit ancient ideas such as the Japanese technique of preserving frail items within multiple boxes. And they will highlight the potential use of styrofoam packaging to economically protect items from rising heat, humidity and other environmental hazards, said an UNU-BIOLAC release.

The Institute of History of Cuba will describe its innovative method to assess objectively the state of heritage photo and document collections, while experts from the Philippines will outline their system of ranking artwork restoration priorities.

Gene therapy proves beneficial for patients with rheumatoid arthritis

Washington, Jan 27 (ANI): German scientists have found evidence that gene therapy reduces symptoms in patients with rheumatoid arthritis.

The study led by an investigator at Beth Israel Deaconess Medical Center (BIDMC) was conducted on two patients with severe rheumatoid arthritis.

Originally conceived as a means of treating genetic diseases, such as cystic fibrosis and hemophilia, gene therapy involves implanting a normal gene to compensate for a defective gene in the patient.

“This study helps extend gene therapy research to nongenetic, nonlethal diseases,” explained principal investigator Christopher Evans, PhD, Director of the Center for Advanced Orthopaedic Studies at BIDMC.

He added: “Rheumatoid arthritis [RA] is an extremely painful condition affecting multiple joints throughout the body. Arthritis is a good target for this treatment because the joint is a closed space into which we can inject genes,” adds Evans, who is also the Maurice Muller Professor of Orthopaedic Surgery at Harvard Medical School.

RA is a classic autoimmune disease, which develops when, for unknown reasons, the body’s immune system turns against itself, causing joints to become swollen and inflamed.

Evans had earlier identified interleukin-1 as a good target for drug therapy to cure the disease. But, he added that there was another question to deal with: How could he effectively reach the joints to block the actions of this protein?

And he found the answer in gene therapy-by implanting a gene in the affected joint, he was able to stimulate production of a human interleukin-1 receptor antagonist protein, which serves to block actions of the interleukin-1 protein.

“The idea is that by remaining in place, the new gene can continuously block the action of the interleukin-1 within the joints. In essence, the gene becomes its own little factory, continuously working to alleviate pain and swelling,” said Evans.

In 2005 Evans and colleagues demonstrated that the IL-1Ra gene could be safely transferred to human joints in patients with RA.

And in the current study, the authors aimed to prove that the therapy was not only safe, but that it was of therapeutic benefit.

For the study, they recruited two subjects, both of whom were postmenopausal females under the age of 75 with a diagnosis of advanced rheumatoid arthritis.

Tissue was removed from the subjects’ knuckle joints and then a harmless retrovirus was inserted into the tissue cells, in order to serve as a “vector” to transport the gene into the patients’ joints.

After being placed in culture to grow and replicate, the cells were injected back into the afflicted joints.

Evans said that after four weeks, patients reported reduced pain and swelling.

“In one of the two subjects, these effects were dramatic, and the gene-treated joints remained pain-free even though other joints experience flares,” he said.

Laboratory tests showed that tissues removed from the subject’s joint tissue synthesized lower amounts of disease-related proteins, which confirmed that the reduction in pain and swelling was due to actions of the implanted gene.

“Existing treatments for rheumatoid arthritis are costly and need to be administered regularly. This paper provides us with the first real evidence that painful symptoms can indeed be lessened through gene therapy,” said Evans, adding that in addition to risk of side effects, not all patients respond well.

Work is going on the use of gene therapy for the treatment of osteoarthritis, as well as rheumatoid arthritis.

The study is published in the upcoming issue of the journal Human Gene Therapy. (ANI)

Russian gas for Europe pumped into Ukrainian pipeline

Russian gas for Europe pumped into Ukrainian pipeline Moscow – The Russian gas monopoly Gazprom began Tuesday to pump gas to Europe into a Ukrainian transit pipeline for the first time since a nearly two-week supply blockade began, the Russian Interfax news agency reported.

The supply resumed after both countries laid aside a bitter dispute over fees and the illegal siphoning of gas, which had cut European countries off from energy supplies in the middle of a harsh winter.

Ukraine said it would not obstruct the deliveries, but experts said even after the taps are reopened, it could take up to three days for gas flows to reach Europe and for pressure to return to normal in the pipelines.

The European Union has been hard hit by the gas row since Russia cut all supplies via Ukraine on January 7, accusing it of stealing gas transits.

Roughly one-quarter of all gas burned in the EU comes from Russia, and 80 per cent of it passes through Ukrainian pipelines.

Hundreds of thousands of people have been left without heating fuel, and factories and schools have been forced to close as sub-freezing temperature swept countries in Eastern Europe most severely affected by the gas cut-off. (dpa)

The computer helper: Intel’s new i7 chips – Core 7

The computer helper: Intel's new i7 chips Washington – Move over, Core 2 Duo. Move over, Core 2 Quad. Intel’s new i7 processor is showing up in new computers around the world. Intel is billing the i7 as “the best desktop processor in the world,” and indeed it offers some substantial improvements – in both speed and architecture – over previous models. But is the i7 worth your money? Will it make help you get your work done faster? And will it make your current PC obsolete? Read on for some answers.

Q: What’s new about the i7?

A: A lot. The i7 was designed from the ground up with speed and energy efficiency in mind. To maximise speed, the i7 includes an new, integrated memory controller that does away with the reliance of previous chips on the so-called “front side bus,” and in its place is a new data transmission channel dubbed QuickPath, which can transmit information at up to 25 gigabytes per second, depending upon chip version.

The first i7s out the door are quad-core designs, and all four cores are integrated onto the same piece of silicon for the first time to increase efficiency. Each core can process two instructions at once – a technology known as multithreading. Thanks to multithreading, each i7 processor looks like eight separate processing units to the operating system.

The i7s also introduce a new type of overclocking called “turbo boost.” Essentially, turbo boost temporarily pushes the performance of individual cores when a program requires it, squeezing more speed out of the chip than it normally provides. Thus chips can push themselves when processing demands are heavy, and they can throttle back to stock speeds under normal computing loads.

For power management and efficiency, the i7 includes a dedicated core that monitors power use, ensuring that the chip balances efficiency with suitable power usage.

Currently there are only three i7 chips available. The i7 920 runs each core at 2.66 GHz and is the most reasonably priced of the three – retailing for under 300 dollars. The i7
940 ups the clock rate per core to 2.93 GHz, but the price of this new chip almost doubles. At the very high end, Intel has the i7 Extreme Edition 965, which runs each core at
3.2 GHz and supports the highest QuickPath transmission speeds.

Q: How much faster are the new chips than today’s core 2 quad chips?

A: Significantly. For standard computing applications as well as processor-intensive video, graphics, and multimedia work, the top-of-the-line i7 processors are up to 64 per cent faster than best-of-breed chips from AMD or former-generation quad core chips from Intel itself.

There is one exception, however: games. The i7 provides little to no performance boost to many of today’s 3D games, mostly because current games do not take advantage of the multithreading technology that the i7 incorporates. Newer games should benefit more from the i7.

Q: Can I upgrade my current dual core processor with an i7?

A: No. The i7 processors use a different socket than today’s dual-core and quad-core processors. The i7 processor itself is larger than previous generation core 2 duo and core 2 quad chips. The larger size is necessary to accommodate the integrated memory controller and other features of the chip.

So if you wanted to upgrade your existing PC to use an i7, at the least you would have to purchase a new chip and a new motherboard – and either have the pair installed or, if you are tech savvy, install the combo yourself. Realistically you would probably also have to purchase new system memory. The i7 relies on DDR3 memory (RAM), which is not found in many systems today. The is the type of upgrade that would necessitate the purchase of an entirely new computer for most users.

Q: Are there both dual-core and quad-core i7 chips?

A: No. The i7 is a quad-core only processor, at least for now. It’s doubtful that a dual-core design will be produced. Four cores – and more – are clearly the future.

Q: If I’m buying a new computer, should I look for one with an i7 processor or look for good deals on machines with older processors?

A: In a period when the tech industry is moving to a new processor architecture, it’s usually not a good idea to look for deals on older technology. That’s because your upgrade path with the older technology will have a shorter lifespan, and the useful lifespan of your equipment may be lessened.

What’s more, the low-end i7 processor is priced competitively with today’s dual core and quad core processors, so you should not face a prohibitively higher price by going with the new technology. In the near term, however, the i7 chips are likely to be marketed in higher end computers. You should start to see prices of i7-based PCs moderate by the middle of this year.

Q: Can I get an i7 in a notebook computer?

A: No. Currently i7 processors are desktop-only. The new i7 chips generate a good deal of heat. Intel has stated that mobile versions of the chip should appear late this year.

— Have a computer question? Send it to the Computer Helper at jayd@csi.com. (dpa)

Entrance at Detroit auto show done by Lincoln C concept car

The paint on the wheels wasn’t dark enough. The seat upholstery needed more embellishment. The instrument panel cried out for one last tweak.

For months, Ford (F) designers scrutinized the creation of their latest baby, the Lincoln C concept car of the future unveiled Monday in Detroit. Though the design was “locked” last spring, they found improvements they could make as the one-of-a-kind show car was built.

The result was revealed to reporters and photographers from around the world at the North American International Auto Show. Later this week, designers and engineers from other automakers will scrutinize the car to try to discern its secrets. Starting Saturday, the public gets a look.

“There’s nothing that gives you more elation than seeing the reaction on people’s faces once it rolls out,” says J Mays, Ford’s design chief, in talking about the C.

The Lincoln C is an attempt to show how a small car can be a luxury showpiece, thanks to elegant design and stylish details. It’s about the size of a Ford Focus, but sports a glass roof, center-opening doors and a powertrain capable of more than 40 miles per gallon on the highway.

There’s no indication that the C — a test-bed for ideas — will ever go into production. But it’s in keeping with Ford’s belief of late in a profitable future for premium small cars.

The C started life on paper and a computer screen. Then it became a full-size clay model. When the design passed muster, Ford turned over the making of the actual concept car to contract builder Aria Group in Irvine, Calif.

Aria re-created the outside by making a mold of the clay model. The interior was designed digitally. And the trick was getting the two to mesh.

Each concept car has its own “little quirks,” says Pete Gallagher, Aria’s chief project manager. In this case, it was trying to get the interior components to fit with the outside shell.

The project was helped along by having a longer build time than normal — about eight months — in which to solve the problems. In the fast-paced world of auto design, Aria’s work often involves last-minute rush jobs.

Ford designers also made changes during the construction process. At one point, they decided the car would look better with darker paint in the crevices of the wheels, said Freeman Thomas, director of Ford’s Strategic Concepts Group.

As interior design chief Gary Braddock watched the crafting of the outside of the car, he saw a way to add a flourish to the instrument panel.

The C had flowers and foliage etched into the seat upholstery after designers feared it looked too plain. Mays says the latest car designs are “so clean and modern, we’ve gotten sterile.”

The resulting C, Mays adds, is a Lincoln that can stand up to the classic simplicity of the brand’s most-admired years — 1939, 1956 and 1961. “You start to see the timelessness of a design,” he says.

The designers and builders alike were pleased with the finished car. “It came out beautiful,” Gallagher says.