Courtney Love wants to revive her acting career

London, May 21 (ANI): Courtney Love is looking to return to the big screen, as she wants to renew her acting career.

The rocker has acted in a few Hollywood films like 200 Cigarettes and Man on the Moon, and has even received nomination for Best Actress Golden Globe for her performance in The People vs. Larry Flynt.

Love, who has been away from Hollywood for a while now, recently released her fourth Hole album, but has now, expressed a wish to return to movies.

“When I first started acting I passed on The Matrix, on L.A. Confidential. I passed on a lot of stuff because I really wasn”t ready to pass on the rock thing. I”m still not ready to give that up but I”d like to do the acting part-time,” The Daily Star quoted her as telling Kerrang! Magazine. (ANI)

Natural hydrogel may boost spinal cord healing

Washington, Sep 18 (ANI): A jab of biomaterial gel into a spinal cord injury site may significantly improve healing, according to researchers at the Barrow Neurological Institute at St. Joseph’s Hospital and Medical Center.

Dr. Mark Preul and Dr. Alyssa Panitch have found in a study that injection of an engineered hydrogel made up mainly of hyaluronic acid (a naturally-occurring body substance) into the spinal cord injury site decreases scarring, and promotes a realignment of the spinal cord fibres around the injury site.

The hyaluronic acid, which forms a scaffold-like configuration may help to structurally stabilize the spinal cord injury site.

The researchers traced cells in the brain stem after injury, and found much higher levels in the hydrogel treated animals as compared to animals that did not receive the treatment, and approached nearly normal levels.

Treated animals had higher functional scores than their non-treated counterparts.

“Spinal cord injury is devastating to civilian and military populations – especially to the young. There has been little progress toward paradigms of regeneration and few results that show real, sustained functional recovery. We’ve been so pre-occupied with regeneration, but that is a highly complicated and difficult to define goal. This project is a synergy of neurosurgeons and bioengineers that attempts repair of the SCI lesion cavity using a tissue-engineering biomaterials approach,” says Preul.

He added that the team aimed at finding ways to structurally allow the body to better heal itself.

“In this project we did not add anything to the hyaluronic acid. It may be that adding growth factors or cells into the gel matrix may allow even better results,” he said.

Preul said that the results show “we may be on a practical path that can give hope to the many people who suffer this sort of injury.”

The work was presented at the Annual Meeting of the American Association of Neurological Surgeons in San Diego where it won the Synthes Prize for Spine Research. (ANI)

BJP- Shiv Sena finalises seat sharing for Maharashtra assembly polls

Mumbai, Aug 31 (ANI): Though the party’s top leadership is struggling to set the house in order, the Bharatiya Janata Party (BJP) Maharashtra unit has finalised the seat sharing agreement with the Shiv Sena on Monday for the upcoming assembly polls in the state.

According to BJP sources the talks with Shiv Sena are almost over and an official announcement would be made in a day or two.

Both the parties agreed for the existing 171:117 formula for the 288 Assembly seats, sources added.

In the 2004 Assembly elections, the Shiv Sena-BJP alliance had allotted seven seats to Shetkari Sanghatana led by vetern farmer’s leader Sharad Joshi. As Joshi’s party is no more a partner of Sena-BJP combine, both the parties are expected to share these seats.

BJP is claiming the Chindwada seat, as the sitting legislator of that constituency joined the party.

The poll managers of the saffron alliance are confident of achieving seat matrix despite trouble faced by the BJP central leadership.

Meanwhile, the ruling Congress – Nationalist Congress Party (NCP) combine is still not sure on maintaining the alliance. Also the strategy of Raj Thackeray’s Maharashtra Navnirman Sena (MNS) is not yet clear.

The MNS is holding its cards close to the chest as to go alone or ally with one of the two major political groups, or opt for the Third Front. (ANI)

Keanu Reaves ‘rekindles romance with ex’

Washington, Aug 28 (ANI): Hollywood actor Keanu Reaves has reportedly rekindled romance with ex-girlfriend Anita Hodson.

According to the Star magazine, the couple is dating again.

The Matrix star met Hodson when she was working as a personal assistant for his mother. They began dating in March 2008, but split soon after.

However, they’re back and inseparable.

“They got together again in the spring. She’s practically moved in with him,” Contactmusic quoted an insider as saying.

“She wants to get married and have his baby. She doesn’t ever want to let Keanu go,” the insider added. (ANI)

Laser beam powered optical transistor may lead to ultrafast light-based computers

London, July 2 (ANI): Swiss researchers have made an optical transistor that uses one laser beam to control another, an instrument that could form the heart of a future generation of ultrafast light-based computers.

Conventional computers are based on transistors, which allow one electrode to control the current moving through the device and are combined to form logic gates and processors.

According to a report in New Scientist, the new component achieves the same thing, but for laser beams, not electric currents.

A green laser beam is used to control the power of an orange laser beam passing through the device.

This offers another possible route to light-based rather than electronic, computing.

Such “photonic” computing is desirable because components using optical fibres carrying light could be much faster than those using wires to carry electricity.

However, previous attempts to make optical transistors for such circuits only produced very weak effects.

The new device could change that.

To make their device, Vahid Sandoghdar and colleagues at the Swiss Federal Institute of Technology in Zurich, suspended tetradecane, a hydrocarbon dye, in an organic liquid.

They then froze the suspension to -272 degrees Celsius using liquid helium – creating a crystalline matrix in which individual dye molecules could be targeted with lasers.

When a finely tuned orange laser beam is trained on a dye molecule, it efficiently soaks up most of it up – leaving a much weaker “output” beam to continue beyond the dye.

But when the molecule is also targeted with a green laser beam, it starts to produce strong orange light of its own and so boosts the power of the orange output beam.

This effect is down to the hydrocarbon molecule absorbing the green light, only to lose the equivalent energy in the form of orange light.

“That light constructively interferes with the incoming orange beam and makes it brighter,” said Sandoghar’s colleague Jaesuk Hwang.

Using the green beam to switch the orange output beam from weak to strong is analogous to the way a transistor’s control electrode switches a current between “on” and “off” voltages, and hence the 0s and 1s of digital data.

Doing it with a single molecule means billions could be packed into future photonic chips. (ANI)

Emerging techniques show promise to repair injured ankle

Washington, July 2 (ANI): A new study has suggested that people with ankle injuries who do not respond successfully to initial treatment may fully recover with the help of two new procedures.

The study reviews emerging techniques that have shown promise in treating injuries to the talus, the small bone, which is located between the heel bone and the lower bones of the leg. The talus helps form the ankle joint.

Lead author Matthew Mitchell, MD, an orthopaedic surgeon in private practice in Casper, Wyoming, said that although most injuries to the talus can be successfully treated using traditional “first-line” therapies involving removal of dead tissue (called “debridement”) and drilling, about one-fifth to one-quarter of people with ankle injuries need additional “second-line” restorative treatment to heal successfully.

He said that the two new techniques rely on cells grown in a lab, and eliminate the need for ostetomy (cutting the bone of the tibia) in some cases.

Autologous chondorcyte implantation, or ACI, involves removing cartilage cells from the knee or the ankle and growing them in a lab. Once grown, the cartilage is transplanted to the talus. ACI usually involves an ostetomy in order to implant the cells.

In matrix-induced autologous chondrocyte implantation, or MACI, cells are grown on a special backing material, or “matrix,” and then transplanted to the talus. In the authors’ experience, an osteotomy is not necessary to implant the cells.

According to Dr. Mitchell, of these two techniques, the newer MACI technique may offer the most benefits to the patient.

“Both ACI and MACI show a lot of promise, but I think the advantage of MACI is that an osteotomy is not necessary in order to successfully implant the matrix. You only need to make an incision to place the graft, which decreases the morbidity of the procedure quite a bit,” he said.

“In my experience so far with this emerging technique in Australia, the results have been as good as, or better than, other restorative techniques,” he added.

The study has been published in the July 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS). (ANI)

New nanotechnology technique may boost longevity of dental fillings

Washington, July 2 (ANI): A novel nanotechnology technique can boost the longevity of dental fillings, claims a Medical College of Georgia (MCG) researcher.

The tooth-coloured fillings are usually more attractive than silver ones, but the bonds between the white filling and the tooth quickly age and degrade.

“Dentin adhesives bond well initially, but then the hybrid layer between the adhesive and the dentin begins to break down in as little as one year. When that happens, the restoration will eventually fail and come off the tooth,” said Dr. Franklin Tay, associate professor of endodontics in the MCG School of Dentistry.

He added: “Our adhesives are not as good as we thought they were, and that causes problems for the bonds.”

To make a bond, a dentist etches away some of the dentin’s minerals with phosphoric acid to expose a network of collagen, known as the hybrid layer.

Acid-etching prepares the tooth for application of an adhesive to the hybrid layer so that the resin can latch on to the collagen network, but the imperfect adhesives leave spaces inside the collagen that are not properly infiltrated with resin, leading to the bonds’ failure.

Thus, in order to prevent the aging and degradation of resin-dentin bonding by feeding minerals back into the collagen network, Tay is investigating guided tissue remineralisation.

Guided tissue remineralisation is a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralised gaps between collagen fibres.

Tay got the idea of the technique by examining how crystals form in nature.

“Eggshells and abalone [sea snail] shells are very strong and intriguing. We’re trying to mimic nature, and we’re learning a lot from observing how small animals make their shells,” said Tay.

The crystals, called hydroxyapatite, bond when proteins and minerals interact.

Tay will use calcium phosphate, a mineral that’s the primary component of dentin, enamel and bone, and two protein analogs also found in dentin so he can mimic nature while controlling the size of each crystal.

“When crystals are formed, they don’t have a definite shape, so they are easily guided into the nooks and crannies of the collagen matrix,” he said.

In theory, the crystals should lock the minerals into the hybrid layer, and prevent it from degrading.

If the concept of guided tissue remineralisation works, Tay will create a delivery system to apply the crystals to the hybrid layer after the acid-etching process.

The study has been published in the Journal of the American Dental Association. (ANI)

Holocaust survivors’ silent behaviours tell their children about their experiences

Washington, June 23 (ANI): A new ethnographic study suggests that the aspects of knowing about a parent’s or grandparent’s Holocaust experiences and traumas are transmitted to other members of the family through unspoken and sometimes unintentional behaviours in the home.

Lead researcher Dr. Carol Kidron, an anthropologist at the University of Haifa, says that this leads to a “knowledge” and presence of the Holocaust that, despite remaining unspoken, contributes to the life experiences and constitutes the personality of the person exposed to it.

During the study, the researchers interviewed 55 children of Holocaust survivors, and found the large majority to reveal that their only knowledge of their parents’ Holocaust experiences were transmitted to them via silent, taken-for-granted everyday interpersonal interaction.

According to them, the children were able to get a sense of their parents’ experiences through the unspoken.

One recalled hearing a parent’s nightly cries. Another remembered wondering about the numbers branded on a parent’s arm, and others described watching their parents reminiscing or looking through old photographs or memorabilia.

Contrary to previous studies that suggested that the children of Holocaust survivors suffer effects of posttraumatic stress disorder (PTSD), Dr. Kidron concluded that 80 percent of the interviewees in the current study did not perceive themselves as suffering from such effects.

Moreover, the “knowledge”, the silent day-to-day presence of Holocaust memories that the descendents of Holocaust survivors gleaned, sufficed: As children, they frequently felt no need to question their parents in depth.

A prominent 95 percent of the interviewees assured that they were not interested in telling the story of their parents’ Holocaust experiences in the public domain, or their own.

“By forming an experiential matrix, these silent traces maintain an intimate and nonpathological presence of the Holocaust death-world in the everyday life-world,” Dr. Kidron said.

According to the researcher, the findings of this study contrast the common belief that a survivor’s silence results in a damaged relationship with his or her children, or in the absence of an inter-generational Holocaust legacy transmitted to the second generation.

It is precisely the presence of the Holocaust past in everyday silent interaction, rather than the vocal transmission of Holocaust testimony or history, that sustains and commemorates the genocidal past in the private familial domain.

The accounts provided by the interviewees in this study “depict the dynamic, normative, and self-imposed silent presence of the Holocaust death-world interwoven with everyday life,” and indicate that children’s relationships with their survivor parents were equally normative.

Dr. Kidron presented the study at a conference hosted by the University of Haifa. (ANI)

CT scans safe, efficient for chest pain diagnosis

Washington, May 16 (ANI): Screening with coronary computerized tomographic angiography (CTA) is a safe and effective way to rule out serious cardiovascular disease in patients who come to hospital emergency rooms with chest pain, according to the first long-term study.

Chest pain is a common and costly health complaint, which makes a large number of patients to reach hospital emergency departments.

Although just five to 15 percent of those patients are found to be suffering from heart attacks or other cardiac diseases, more than half are admitted to the hospital for observation and further testing.

Researchers from the University of Pennsylvania School of Medicine found that CTA streamlines the process and provides a faster, and less expensive way to evaluate which patients have an acute coronary syndrome that require treatment.

“The ability to rapidly determine that there is nothing seriously wrong allows us to provide reassurance to the patient and to help reduce crowding in the emergency department. The use of this test is a win-win,” said lead author Dr. Judd Hollander, professor and clinical research director in Penn’s department of Emergency Medicine.

None of the patients enrolled in the trial after getting a negative scan – a scan showing no evidence of dangerous blockages in the coronary arteries – had heart attacks or required bypass surgery or placement of cardiac stents in the year following their test.

According to the authors, the findings provide a roadmap for how to appropriately and cost-effectively use this advanced imaging technology, which generates lifelike, three-dimensional photos of the heart and the matrix of blood vessels that surround it.

Investigators followed 481 patients who received negative CTA scans for one year after their hospital visit-11 percent of patients were rehospitalized and 11 percent received additional cardiac testing – stress tests or cardiac catheterizations – over the following year.

But, none had heart attacks or needed revascularization procedures to prop open blocked coronary arteries, while one patient in the study died of an unrelated cause during the year.

In earlier studies, it was shown that CTA is both a quicker and less expensive way to screen low-risk chest pain patients than conventional testing methods.

Those studies also showed that CTA helps get patients home faster.

“The evidence now clearly shows that when used in appropriate patients in the ED, we can safely and rapidly reduce hospital admission and save money. It seems time to make a national coverage decision that will facilitate coronary CTA in the emergency department,” said Hollander.

The study was presented at the Society for Academic Emergency Medicine’s annual conference. (ANI)

Dirty Dancing polled Britain’s Top Film

Washington, May 14 (ANI): Dirty Dancing is Britons’ favourite film, according to a new online poll.

The 1987 movie, starring Patrick Swayze and Jennifer Grey, pipped The Shawshank Redemption and Star Wars to top the poll to find Britain’s favourite film.

The survey was carried out by the Cinema Advertising Association, reports Contactmusic.

High School Musical, Lord Of The Rings, Grease and Mamma Mia! landed fourth, fifth, sixth and seventh spots respectively.

The Sound Of Music, The Matrix and Gone With The Wind rounded off the top ten.

The top 10 movies:

1. Dirty Dancing

2. The Shawshank Redemption

3. Star Wars

4. High School Musical

5. Lord Of The Rings

6. Grease

7. Mamma Mia!

8. The Sound Of Music

9. The Matrix

10. Gone With The Wind. (ANI)

Sea urchins’ digging teeth are designed to stay sharp

Washington, May 5 (ANI): Scientists at Weizmann Institute, US, have revealed how the teeth of sea urchins are designed to stay sharp, which might give engineers insights into creating ever-sharp tools or mechanical parts.

The urchins dig holes to fit their globular bodies using their five teeth, which, like those of rodents, are ground down at the tip but continue to grow on the other end throughout the animals’ lives.

The amazing part, however, is that the teeth, which need to be harder and stronger than the rocky limestone being dug out, are themselves made almost entirely of calcite – the same calcite that makes up much of the limestone.

In a series of studies spanning more than a decade, Professors Steve Weiner and Lia Addadi of Weizmann’s Structural Biology Department have discovered that the urchins’ secret lies in a combination of ingenious design strategies.

In the latest of these studies, the scientists found that the sea urchins’ teeth contain crystals of magnesium calcite, which are smaller, harder and denser than those of pure calcite.

They are concentrated at the grinding tip of the tooth, particularly in the tip’s center, where the most force is being exerted in the course of grinding.

What holds these crystals at the center of the tip is a matrix of larger and softer calcite crystals.

While in most such materials a matrix of hard fibers contains a softer filling, the reverse is true for the urchins’ tooth.

A matrix of relatively soft calcite fibers holds the harder magnesium calcite crystals, which allows these crystals to spread over the entire surface of the tooth.

The presence of magnesium calcite crystals acts like sand paper that helps to grind the rock down.

In the latest study, the researchers used X-ray photoelectron emission spectromicroscopy and other high-resolution imaging methods to uncover yet another amazing structural feature of sea urchin tooth design.

They found that all the crystalline elements that make up the tooth are aligned in two different arrays, and that these arrays are ‘interdigitated,’ or interlocked like the fingers of folded hands, just at the tip of the tooth where most of the wear occurs.

The scientists believe that interlocking produces a notched, serrated ridge resembling that of a carpenter’s file.

This ridge is self-sharpening: as the tooth is being ground down, the crystalline layers break in such a way that the ridge always stays corrugated. (ANI)

Berries may help keep wrinkles at bay

Washington, Apr 22 (ANI): The latest beauty cream that can be added in a woman’s skin care regimen can be found in berries. A new study has found that an antioxidant present in the fruit could help fight skin damage due to ultraviolet (UV) rays.

Using a topical application of the antioxidant ellagic acid, researchers at Hallym University in the Republic of Korea markedly prevented collagen destruction and inflammatory response – major causes of wrinkles – in both human skin cells and the sensitive skin of hairless mice following continuing exposure to UV-B, the sun’s skin-damaging ultraviolet radioactive rays.

Ji-Young Bae, a graduate student in the laboratory of Dr. Young-Hee Kang, presented results of the two-part study on April 21, at the Experimental Biology 2009 meeting in New Orleans. The presentation was part of the scientific program of the American Society for Nutrition.

Ellagic acid is an antioxidant found in numerous fruits, vegetables and nuts, especially raspberries, strawberries, cranberries and pomegranates. Earlier studies have suggested it has a photoprotective effect.

The Kang laboratory found that, in human skin cells, ellagic acid worked to protect against UV damage by blocking production of MMP (matrix metalloproteinase enzymes that break down collagen in damaged skin cells) and by reducing the expression of ICAM (a molecule involved in inflammation).

The scientists then turned to young (four weeks), male, hairless mice – genetically bred types of mice often used in dermatology studies because of the physiological similarities of their skin to that of humans. For eight weeks, the 12 mice were exposed to increasing ultraviolet radiation, such as that found in sunlight, three times a week, beginning at a level sufficient to cause redness or sunburn and increasing to a level that would have definitely caused minor skin damage to human skin.

During these eight weeks, half of the exposed mice were given daily 10 microM topical applications of ellagic acid on their skin surface, even on the days in which they did not receive UV exposure. The other mice, also exposed to UV light, did not receive ellagic acid.

Following the analyses, the mice exposed to UV radiation without the ellagic acid treatment developed wrinkles and thickening of the skin, the researchers found.

Second, as hypothesized, the exposed mice that received topical application of ellagic acid showed reduced wrinkle formation.

Third, as suggested in the study of human cells, the ellagic acid reduced inflammatory response and MMP secretion due to protection from the degradation of collagen. The ellagic acid also helped prevent an increase of epidermal thickness.

The researchers say the results demonstrate that ellagic acid works to prevent wrinkle formation and photo-aging caused by UV destruction of collagen and inflammatory response. (ANI)

Gene that suppresses skin cancer growth identified

London, March 30 (ANI): Scientists at the National Institutes of Health (NIH) in the U.S. have announced the discovery of a gene that suppresses tumour growth in melanoma, the deadliest form of skin cancer.

The finding was made as part of a systematic genetic analysis of a group of enzymes implicated in skin cancer, and many other types of cancer.

According to the analysis, one-quarter of human skin cancer tumours had mutations in genes that code for matrix metalloproteinase (MMP) enzymes.

The researchers believe that their findings may pave the way for more individualized cancer treatment strategies, where MMP and other key enzymes play a functional role in tumour growth and spread of the disease.

They even say that their study may help understand why drugs designed to treat cancer by blocking MMP enzymes have not been very successful as yet.

During the current study, the team led by researchers from the National Human Genome Research Institute (NHGRI) have found that MMP-8 actually serves as a tumour suppressor gene in melanoma, which is why may not be wise to block all MMPs in skin cancer patients with mutation in this gene.

The researchers say that a better approach may be to look for drugs that restore or increase MMP-8 function, or for drugs that block only those MMPs that are truly oncogenes-genes that encode proteins involved in normal cell growth.

“This research is an illustrative proof of concept that shows the value of genomic strategies for understanding cancer and possible therapies,” Nature magazine quoted Dr. Eric Green, NHGRI Scientific Director, as saying.

“It is gratifying to see that genomic technologies are guiding scientific discovery, advancing cancer research, especially melanoma research,” Green added.

While experimenting on mice, the researcher observed that when they injected the animals with cells expressing normal MMP-8, they would not develop skin ulcers.

However, when the mice were injected with cells expressing mutated MMP-8, they went on to develop ulcerations and metastases in their lungs.

A research article on the gene discovery has been published in the journal Nature Genetics. (ANI)

Jada Pinkett-Smith laughs off ‘sham marriage’ rumours

Washington, Mar 27 (ANI): Jada Pinkett Smith has laughed off rumours that her marriage to Will Smith is just a veil to hide their real sexual orientations.

She was responding to online gossipmongers who recently claimed that the couple’s love was not for real, and that they were both secretly gay.

However, the ‘Matrix Reloaded’ star is unfazed by all such reports, insisting there is nothing she could say to convince her marriage critics.

“I don’t have an open marriage and no, we’re not gay – and you don’t trust that? Well then there’s nothing that I really have to say to anybody about anything, because at the end of the day, I’m living my life, and I’m happy,” Contactmusic quoted Pinkett Smith as telling American news organisation National Public Radio.

The Hollywood couple celebrate their twelfth wedding anniversary this year.

Will and Jada have two children together: son Jaden, 10, and daughter Willow, eight.

The ‘I Am Legend’ actor also has a 16-year-old son, Trey, from a previous relationship. (ANI)

Mamma Mia! becomes biggest selling UK DVD ever

London, Jan 1 (ANI): Mamma Mia! the movie has become the biggest-selling DVD in the UK ever.

According to the Official Charts Company, the release racked up enough sales during the Christmas break to become the first disc to sell more than five million DVDs.

Mamma Mia! has already been named as the fastest-selling DVD, selling 1.669 million on its first day of sale.

The movie soundtrack has been confirmed as the biggest selling compilation of 2008, with a million copies flying off the shelves

It has beaten ”Pirates Of The Caribbean: The Curse Of The Black Pearl”, which has sold 4.7 million copies in the UK.

“Right from its release, Mamma Mia! has been a record breaker – when it was issued on DVD, it became the fastest seller of all time,” the Telegraph quoted Official Charts Company managing director Martin Talbot, as saying.

“This latest landmark further underlines the popularity of the movie, which is now ”officially” the British public”s favourite DVD of all time – with one-in-four British households owning a copy,” Talbot added.

Here is the official all-time DVD top 50 from 1998 to 2008:

1. Mamma Mia! The Movie
2. Pirates of the Caribbean: The Curse of the Black Pearl
3. The Lord of the Rings: Fellowship of the Ring
4. The Lord of the Rings: The Two Towers
5. Casino Royale
6. Pirates of the Caribbean: Dead Man”s Chest
7. The Shawshank Redemption
8. Gladiator
9. The Lord of the Rings: The Return of the King
10. Shrek 2
11. Harry Potter & the Goblet of Fire
12. Finding Nemo
13. Grease
14. Harry Potter & the Prisoner of Azkaban
15. Madagascar
16. Love Actually
17. Dirty Dancing
18. Harry Potter & the Chamber of Secrets
19. The Simpsons Movie
20. Harry Potter & the Order of the Phoenix
21. The Day After Tomorrow
22. Transformers
23. Hot Fuzz
24. Pirates of the Caribbean: At World”s End
25. The Chronicles of Narnia: The Lion, The Witch & The Wardrobe
26. War of the Worlds
27. Ocean”s Eleven
28. Bridget Jones”s Diary
29. Harry Potter & the Philosopher”s Stone
30. Spiderman
31. Shrek
32. I Robot
33. Charlie & the Chocolate Factory
34. Saving Private Ryan
35. Shrek the Third
36. Star Wars III: Revenge of the Sith
37. The Da Vinci Code
38. The Incredibles
39. Troy
40. The Matrix
41. The Green Mile
42. High School Musical
43. Monsters Inc
44. The Matrix Reloaded
45. The Bourne Identity
46. Bridget Jones: The Edge of Reason
47. Ice Age 2: The Meltdown
48. The Polar Express
49. Star Wars: Trilogy
50. Shaun of the Dead

(ANI)