Lose weight quickly, not gradually, for long-term success

Washington, May 6 (ANI): The key to long-term weight loss and maintenance is to lose weight quickly, not gradually, in the initial stages of obesity treatment, suggests a new study.

As part of the study, Lisa Nackers and colleagues, from the University of Florida in the US, and her team examined the association between rate of initial weight loss and long-term maintenance of lost weight, by looking specifically at whether losing weight at a slow initial rate results in larger long-term weight reduction and less weight regain than losing weight at a fast initial rate.

The authors analyzed data for 262 middle-aged obese women who took part in the Treatment of Obesity in Underserved Rural Settings (TOURS) trial.

These women followed a six-month lifestyle program encouraging them to reduce their calorie intake and increase their moderate intensity physical activity to achieve an average weight loss of 0.45kg per week.

They were then supported for a further year with an extended care program involving contact twice a month in the form of group sessions, telephone contact or newsletters.

Nackers and team split the women into three groups according to how much weight they lost in the first month of the intervention. Women in the FAST group lost over 0.68kg per week; those in the MODERATE group lost between 0.23 and 0.68kg per week; women in the SLOW group lost less than 0.23kg per week in that first month.

The authors then looked at the womens” weight loss at 6 and 18 months, as well as any weight regain.

They found that there were long-term advantages to fast initial weight loss.

Fast weight losers lost more weight overall, maintained their weight loss for longer and were not more likely to put weight back on than the more gradual weight losers.

In particular, women in the FAST group were five times more likely to achieve the clinically significant 10 percent weight loss at 18 months than those in the SLOW group and those in the MODERATE group were nearly three times more likely to achieve this milestone than women in the SLOW group.

“Our study provides further evidence that, within the context of lifestyle treatment, losing weight at a fast initial rate leads to greater short-term weight reductions, does not result in increased susceptibility to weight regain, and is associated with larger weight losses and overall long-term success in weight management. We suggest that, within lifestyle weight control programs, substantial efforts should be focused on promoting large rather than small behavioral changes during the initial weeks of treatment,” the authors said.

Their findings are published online in International Journal of Behavioural Medicine. (ANI)

Supplementary Nutrition Programme benefits women in Faizabad

Faizabad, May 8 (ANI): Union Government’s Supplementary Nutrition Programme has greatly benefited women and children in Faizabad by curbing malnutrition among the poor families.

Government started the scheme with focus on improving the health and nutritional status of infants aged till six years, pregnant women and lactating mothers.

Under this programme, infants below six years of age are given cooked meals at the school while women in advanced stage of pregnancy are given weekly dry nutrient preparations.

The aim is to supplement the daily nutritional intake by 300 calories, 8 to 10 grams of protein for children, 500 calories and 20-25 grams of protein for women under the ante-natal and post-natal care.

“For children between three to six years, we give hot cooked food, for children below three years of age, we distribute nutritional food. The distribution is done weekly. Some people come here, while for those who cannot; our volunteers visit them by covering the entire area to distribute the food,” said Sunita Soni, Supervisor, Supplementary Nutritionrogramme, Faizabad.

The response of the program has gradually increased unlike the initial stages when many conservative women refused to come out of their mud-houses.

To advise the womenfolk about health and pregnancy related issues, regular ‘Mahila Mandals’ (women council meetings) are organized as part of this program.

Supplementary nutrition is provided as per the programme to needy children and women for 300 days in a year.

“They give us scholarships, Panjiri (traditional formulation of nutrients), good food and books. The programme run by the Indian government is good,” said Ramkumari, a local beneficiary, Faizabad.

Pregnant women are also provided with basic counseling about immunization, iron supplementation and special care for young children. (ANI)

Keeping mentally fit: the daily crossword is not enough

Bonn, Germany – A man sits on a train solving a crossword puzzle, a woman broods over a Sudoku grid while an ad for an electronic memory game flashes across a television screen. There is no shortage of ways to improve the brain’s memory powers – after all, lots of people want to improve their mental abilities.

But are Sudoku, crosswords and other training games any good at improving memory? Are they really effective in training the mind or just a nice way of passing the time?

“If you train your brain, you can improve your performance,” says Carsten Brandenburg from Germany’s Memory Training Association. But not every exercise can radically change a person’s ability to remember things.

“If you repeat the same kind of exercise, your mind gets into a routine, and there is no challenge anymore,” says Brandenburg.

Sudoku is most effective in the initial stages. “The brain is not used to thinking in that manner and that’s why new connections are made between the individual nerve cells,” explains Brandenburg.

The chairwoman of the Professional Association of German Psychiatrists, Christa Roth-Sackenheim says, “We have recently come to understand that the human brain can make new connections and even new paths.”

That explains why Sudoku and computer memory games can have a positive effect on the brain’s memory performance. “You don’t just improve your concentration, you also practice strategic thinking and how to link different facts,” explains the psychiatrist. That ability can be useful in daily life.

The most effective puzzles are those that test more than your existing knowledge which excludes puzzles such as crosswords.

There are a number of books and games for electronic consoles that go in that direction, according to Brandenburg, who also works as a memory coach at Germany’s Memory Clinic in Essen.

“The best exercises are well designed and gradually become more challenging as they progress,” he says.

But computer games and electronic memory puzzles are not all-purpose weapons against memory loss, says psychiatrist Michael Rapp from Berlin’s Charite University Hospital.

“There is no exercise that can make a person more intelligent overall,” says the head of the clinic’s geriatric psychiatry working group.

You don’t need to buy expensive games to keep your brain fit. If you follow a few pointers every day, you will improve your memory or at the very least, keep it at the present level.

“Communicating is essential,” says Brandenburg, adding, “That’s how you learn to query things, gain new knowledge and grapple with questions.”

Another way of improving memory is to learn a new language, according to Roth-Sackenheim. Listening to music, doing domestic chores alone or pursuing a hobby can also help.

“Engaging in physical exercise is important for all age groups,” says Roth-Sackenheim. “That’s because sport trains the brain because you have to remember certain physical movements and practice your coordination.”

There is another alternative – keeping busy with your grandchildren. When elderly people try to understand young people’s lives, they also exercise their brains. (dpa)

Sports teams’ rankings don’t affect their chances of success deeper into any tournament

Washington, March 17 (ANI): Sports teams’ rankings may predict their chances of winning during the initial stages of any tournament, but they start becoming statistically insignificant as the final round draws near, says a University of Illinois expert.

Sheldon H. Jacobson, a professor of computer science, says that the higher-seeded teams are most likely to beat their lower-seeded opponents in the first three rounds of an NCAA Men’s Basketball Tournament.

He, however, add that once the field has been winnowed to the so-called “Elite Eight” teams, each team’s odds of winning are statistically equal, no matter how high or low the teams were initially ranked at the start of the tournament.

“The deeper you get into the tournament, the less effective seeding is in predicting winners,” Jacobson says.

Jacobson says that for the 12 teams that comprise the top three seeds in each of the four regional brackets, seeding is an “excellent predictor” of the outcomes of the first three rounds of games with those teams.

“In the first round, the No. 1 seed has beaten the No. 16 seed 100 percent of the time,” he says.

“But after the Sweet Sixteen, it is a statistical toss-up as to who wins the remaining games. A team’s seeding can be thrown out the window. They really do not give you a good indication of who is going to win the games,” he adds.

Jacobson says that the impetus of the study was not to predict brackets or winners in advance of the tournament, but to see if the top three teams’ seeding in each bracket is a good predictor of how far they will go in the “Big Dance.”

“I have always been surprised that the first seeds seem to do better than the second seeds, who seem to do better than the third seeds, because you would think that there is not really a big difference between the top three seeds from each of the four regions,” he says.

As to whether there is a statistically significant difference between what are ostensibly the top 12 teams in the country, he says: “The answer is both ‘yes’ and ‘no’.

There are differences, but it is not a question as to whether they are different; it is a question as to when they are different, based on the rounds of the tournament. Seeds are important, but they start to lose their strength beginning in the Sweet Sixteen round. By the time they reach the Elite Eight, those teams were not statistically different than anyone else in the field.”

Despite its weakness as a predictive model, Jacobson doesn’t believe the seed-based ranking system used by the NCAA needs to be replaced wholesale.

“The committee has a very challenging job seeding the teams, and the tournament format by design is exciting,” he said.

“We are talking about bringing 65 teams together from all the major conferences – the Big Ten, Big 12, SEC, PAC-10, ACC and the Big East – and then you have many teams that you rarely see on national television. But it should not change the seeding system, since seeds are not designed to predict the winner of each game, but rather, are based on a resume of performance for an entire season.”

An article about Jacobson’s observations, which he has written along with graduate student Douglas M. King, will be published in a forthcoming issue of the Journal of Gambling Business and Economics.(ANI)

Targeting HIV in initial stages of infection may prevent virus from spreading

London, Feb 18 (ANI): A new study suggests that vaccines, which specifically target HIV in the initial stages of infection before it becomes a rapidly replicating, system-wide infection, may be a successful approach in limiting the spread of the disease.

Researchers at Oregon Health and Science University’s Vaccine and Gene Therapy Institute used a vaccination method that involves creating and maintaining resistance by programming a portion of the body’s immune system – effector memory T-cells – to look out for HIV at the site of infection.

“HIV appears to be vulnerable when it is first introduced into mucosal surfaces in the body,” said Louis Picker, M.D., associate director of the OHSU VGTI and director of the VGTI’s vaccine program.

“However, once HIV spreads throughout the entire body, it replicates very rapidly and becomes difficult if not impossible to control. Our approach is to attack during this early period of vulnerability. The approach is similar to that of a homeowner who sprays their house with water before sparks land on the roof. This approach can prevent the roof from catching fire and, in the case of HIV, prevent the spread of the virus,” Picker added.

To determine whether they could proactively “educate” the immune system, scientists used a monkey model of AIDS – simian immunodeficiency virus (SIV) – the monkey counterpart to HIV.

They introduced an altered monkey form of cytomegalovirus (CMV) programmed to express SIV proteins and trigger specialized effector memory T-cells to look for and attack SIV in its early stages.

In total, 12 rhesus macaque monkeys were vaccinated using this method. When the animals were later infected with SIV, one-third were protected.

The research team’s next step is to try to determine why only a portion of the monkeys who are vaccinated using this method are responding.

They also hope to expand the number of subjects to better determine the success rate of the therapy.

The research is published in the early online edition of the journal Nature Medicine. (ANI)

Tots who use gestures more have better vocabulary at kindergarten age

Washington, Feb 13 (ANI): Children who use gestures more as toddlers have a good vocabulary, and are better prepared for school, according to a new study from University of Chicago.

The researchers found that children who convey more meanings with gestures at age 14 months have much larger vocabularies when they enter kindergarten.

Susan-Goldin Meadow, who co-authored the study, said the research showed that the differences particularly favoured children from higher-income families with well-educated parents.

During the study, the research team analysed 50 Chicago-area families from diverse economic backgrounds.

“Vocabulary is a key predictor of school success and is a primary reason why children from low-income families enter school at a greater risk of failure than their peers from advantaged families,” said Goldin-Meadow.

They recorded video of children and primary caregivers for 90-minute sessions during ordinary activities at home.

The analysis showed that differences in gesture appeared early among children.

Researchers found that frequent early gesture among children is connected to stronger verbal skills entering kindergarten.

“It is striking that, in the initial stages of language learning when SES (socioeconomic status) differences in children’s spoken vocabulary are not yet evident, we see SES differences in child gesture use,” Rowe said.

“Children typically do not begin gesturing until around 10 months,” she added.

“Thus, SES differences are evident a mere four months, and possibly even sooner, after the onset of child gesture production,” she added.

The study also showed that fourteen-month-old children from high-income, well-educated families used gesture to convey an average of 24 different meanings during the 90-minute session, while children from lower-income families conveyed only 13.

Moreover, once in school, students from higher-income families had a comprehension vocabulary of 11 compared to 93 for children from lower-income families.

“Child gesture could play an indirect role in word learning by eliciting timely speech from parents; for example, in response to her child’s point at the doll, mother might say, ‘yes, that’s a doll,’ thus providing a word for the object that is the focus of the child’s attention,” wrote the authors. (ANI)