Office vacancy rate hits 16-year high

(Reuters) – The U.S. office vacancy rate in the first quarter reached its highest level in 16 years, but the decline in rents eased and crept closer to stabilization, according to a report by real estate research firm Reis Inc.

U.S. | Housing Market

The U.S. office vacancy rate rose to 17.2 percent, a level unseen since 1994, as the market lost about 11.6 million net square feet of occupied space during the first quarter, according to the report released on Monday. The U.S. vacancy rate inched up 0.2 percentage points from a quarter earlier and was 2 percent higher than a year ago.

“As labor markets stabilize, we expect occupancies and rents to require another 12 to 18 months before showing signs of improvement, given typical lags in commercial real estate,” Reis director of research Victor Calanog said in a statement. “Even as occupancy continues to deteriorate, we’re observing signs of renewed leasing activity across different metros.”

The U.S. office vacancy rate hit a cyclical low of 12.5 percent in the third quarter 2007.

Rental rates fell an average of 0.8 percent in the first quarter, a less steep decline that seen last year. Asking rent fell 4.2 percent from a year earlier. Factoring months of free rent and landlord contributions to space improvements for each tenant, effective rent was down 7.4 percent from a year earlier.

Both asking and effective rent were off 0.8 percent from the fourth quarter 2009. The fact that effective rent is no longer falling at a greater rate than asking rent is an indication that landlords may have offered enough concessions to stimulate leasing activity.

“While we do not foresee positive rent growth resuming until next year at the earliest, office buildings at least do not seem to be experiencing as much distress relative to 12 months ago, when we were just heading into 2009 and most markets and economies around the world were still in deep turmoil,” Calanog said.

LESS OF A BLOODBATH IN 2010

“We expect less of a bloodbath in fundamentals in 2010 versus 2009, but rents will still decline and vacancies will still continue to rise,” Calanog said. “This is bad news for loans supported by office properties that have to contend with at least six to eight more quarters of falling income.”

Tight credit markets also have curbed office construction with only 3.6 million square feet of office space coming online, the lowest level of completions since Reis began publishing quarterly data in 1999.

The office vacancy rate increased in 57 of the 79 primary metropolitan areas Reis tracks. Effective rents fell in 56 out of 79 markets, down from 70 in the fourth quarter 2009.

New York, the largest office market, saw its vacancy rate rise 0.1 percentage point to 11.7 percent from 11.6 percent. Effective rent slid 2.1 percent, less than half the 5.3 percent drop seen in the fourth quarter 2009.

Washington DC has overtaken New York as Reis’s tightest market, with DC sporting the nation’s lowest vacancy rate of 10.4 percent. Detroit, home of the U.S. auto industry, continued to suffer the most, with a 26.2 percent vacancy rate, the highest in the nation.

(Reporting by Ilaina Jonas; Editing by Lincoln Feast)

U.S. office vacancy rate hits 16-year high

NEW YORK, April 5 (Reuters) – The U.S. office vacancy rate in the first quarter reached its highest level in 16 years, but the decline in rents eased and crept closer to stabilization, according to a report by real estate research firm Reis Inc.

The U.S. office vacancy rate rose to 17.2 percent, a level unseen since 1994, as the market lost about 11.6 million net square feet of occupied space during the first quarter, according to the report released on Monday. The U.S. vacancy rate inched up 0.2 percentage points from a quarter earlier and was 2 percent higher than a year ago.

“As labor markets stabilize, we expect occupancies and rents to require another 12 to 18 months before showing signs of improvement, given typical lags in commercial real estate,” Reis director of research Victor Calanog said in a statement. “Even as occupancy continues to deteriorate, we’re observing signs of renewed leasing activity across different metros.”

The U.S. office vacancy rate hit a cyclical low of 12.5 percent in the third quarter 2007.

Rental rates fell an average of 0.8 percent in the first quarter, a less steep decline that seen last year. Asking rent fell 4.2 percent from a year earlier. Factoring months of free rent and landlord contributions to space improvements for each tenant, effective rent was down 7.4 percent from a year earlier.

Both asking and effective rent were off 0.8 percent from the fourth quarter 2009. The fact that effective rent is no longer falling at a greater rate than asking rent is an indication that landlords may have offered enough concessions to stimulate leasing activity.

“While we do not foresee positive rent growth resuming until next year at the earliest, office buildings at least do not seem to be experiencing as much distress relative to 12 months ago, when we were just heading into 2009 and most markets and economies around the world were still in deep turmoil,” Calanog said.

LESS OF A BLOODBATH IN 2010

“We expect less of a bloodbath in fundamentals in 2010 versus 2009, but rents will still decline and vacancies will still continue to rise,” Calanog said. “This is bad news for loans supported by office properties that have to contend with at least six to eight more quarters of falling income.”

Tight credit markets also have curbed office construction with only 3.6 million square feet of office space coming online, the lowest level of completions since Reis began publishing quarterly data in 1999.

The office vacancy rate increased in 57 of the 79 primary metropolitan areas Reis tracks. Effective rents fell in 56 out of 79 markets, down from 70 in the fourth quarter 2009.

New York, the largest office market, saw its vacancy rate rise 0.1 percentage point to 11.7 percent from 11.6 percent. Effective rent slid 2.1 percent, less than half the 5.3 percent drop seen in the fourth quarter 2009.

Washington DC has overtaken New York as Reis’s tightest market, with DC sporting the nation’s lowest vacancy rate of 10.4 percent. Detroit, home of the U.S. auto industry, continued to suffer the most, with a 26.2 percent vacancy rate, the highest in the nation. (Reporting by Ilaina Jonas; Editing by Lincoln Feast)

Stem cell transplantation may correct rare genetic disorder in kids

Washington, Sep 18 (ANI): Scripps Research Institute scientists have offered new hope for parents whose children suffer from the rare genetic disorder ‘cystinosis’ by showing through an experiment on mice that stem cell transplantation can successfully correct the defect.

“After meeting the children who suffer from this disease, like an 18-year-old who has already had three kidney transplants, and the families who are desperately searching for help, our team is committed to moving toward a cure for cystinosis, a lysosomal storage disorder. This study is an important step toward that goal,” said principal investigator Stephanie Cherqui.

In the study, the researchers used bone marrow stem cell transplantation to address symptoms of cystinosis in a mouse model.

The procedure virtually halted the cystine accumulation responsible for the disease, and the cascade of cell death that follows.

Cystine is a by-product of the break down of cellular components the body no longer needs in the cell’s “housekeeping” organelles, called lysosomes.

Normally, cystine is shunted out of cells, but in cystinosis a gene defect of the lysosomal cystine transporter causes it to build up, forming crystals that are especially damaging to the kidneys and eyes.

Cystinosis is a rare but devastating disease affecting children as young as six months, who begin to suffer renal dysfunction, which grows progressively worse with time. Other symptoms include diabetes, muscular disease, neurological dysfunction, and retinopathy.

The only available drug to treat cystinosis, cysteamine, while slowing the progression of kidney degradation, does not prevent it, and end-stage kidney failure is inevitable.

In the new study, the researchers found that transplanted bone marrow stem cells carrying the normal lysosomal cystine transporter gene abundantly engrafted into every tissue of the experimental mice.

This led to an average drop in cystine levels of about 80 percent in every organ.

Not only it prevented kidney dysfunction, there was less deposition of cystine crystals in the cornea, less bone demineralization, and an improvement in motor function.

“The results really surprised and encouraged us. Because the defect is present in every cell of the body, we did not expect a bone marrow stem cell transplant to be so widespread and effective,” says Cherqui.

Cherqui said that adult bone marrow stem cell therapy is particularly well suited as a potential treatment for cystinosis because these cells target all types of tissues.

In addition, stem cells reside in the bone marrow for the duration of a patient’s life, becoming active as needed, a particular benefit for a progressive disease like cystinosis.

The study has been published in the journal Blood. (ANI)

Ponting’s 27th ton helps Australia beat England in fifth ODI

Nottingham (UK), Sep.16 (ANI): Ricky Ponting scored a brilliant 126 of 109 balls to keep Australia in the hunt for a 7-0 whitewash of their one-day series against England, leading his side to a four-wicket victory in the fifth one-day international at Trent Bridge on Tuesday.

Ponting’s 27th ton in ODIs included three sixes and 14 fours, as Australia raced to 302 for six wickets with 10 balls to spare in reply to England’s total of 299 from their 50 overs.

He was well supported by deputy Michael Clarke, who reached 52 off 64.

Irishman Eoin Morgan’s maiden half-century steered England to their best score of the series in a dead rubber after Australia clinched the series 4-0 at Lord’s on Saturday.

Mitchell Johnson brought up the winning runs with a six off Ryan Sidebottom to remain unbeaten on 18, while Cameron White was not out 24.

Poor fielding frustrated England captain Andrew Struass, who demanded improvement from his batsmen after the first four matches.

“Our batters went out and played with a much more bold approach and that paid dividends today. The fielding was poor and that’s something that there should be no excuse for, we do a lot of work on the fielding and we should be better than that,” Fox Sports quoted Strauss, as saying.

The tourists rested Brett Lee, who claimed five wickets in the previous match, replacing him with fellow pacer Peter Siddle.

England brought in Mascarenhas for Luke Wright, who was hit on the toe on Monday while batting against a bowling machine set to mimic Lee’s inswinging yorkers which proved so effective last weekend.(ANI)

Exercise beats shockwaves for chronic shoulder pain

London, Sept 16 (ANI): Supervised exercise helps ease chronic shoulder pain better than sound shockwave treatment, a new study suggests.

In the study, published in the online British Medical Journal, team of researchers based in Oslo, Norway compared the effectiveness of radial extracorporeal shockwave treatment (low to medium energy impulses delivered into the tissue) with supervised exercises in patients with shoulder pain.

The research involved 104 men and women aged between 18 and 70 years.

Participants were randomised to receive either radial extracorporeal shockwave treatment (one session weekly for four to six weeks) or supervised exercises (two 45 minute sessions weekly for up to 12 weeks).

Both groups were similar at the start of the study with regard to age, education, dominant arm affected and pain duration.

All patients were monitored at six, 12 and 18 weeks and were advised not to have any additional treatment except analgesics (including anti-inflammatory drugs) during the follow-up period. Pain and disability were measured using a recognised scoring index.

After 18 weeks, 32 of patients in the exercise group achieved a reduction in shoulder pain and disability scores compared with 18 in the shockwave treatment group.

More patients in the exercise group returned to work, while more patients in the shockwave treatment group had additional treatment after 12 weeks, suggesting that they were less satisfied.

The authors conclude: “Supervised exercises were more effective than radial extracorporeal shockwave treatment for short term improvement in patients with subacromial shoulder pain.” (ANI)

We will not let Commonwealth Games suffer: Shiela Dixit

New Delhi, Sep 14 (ANI): A day after the chief of Commonwealth Games Federation (CGF) Michael Fennel expressed reservations regarding the completion of work and preparations for the 2010 Commonwealth Games, Delhi Chief Minister Sheila Dixit on Monday admitted that there was enough room for improvement and it is being taken care of.

“We are monitoring transport carefully, we are also looking for alternatives. But, there may be things we are unable to complete on time. But, the alternatives are being looked after by our PWD (Public Works Department) Minister, our Transport Minister, our power guys, everyone. So, we will not, from our side, let the Commonwealth games to suffer,” Dixit told media after a cabinet meeting in the national capital.

“We are satisfied, but at the same time we are also nervous. There are many things, which we know, have to be done at this time,” Sheila Dixit Delhi CM said.

Fennel has expressed dissatisfaction over the preparations of the Commonwealth Games and has sought Prime Minister Manmohan Singh’s intervention in the issue.

Dixit also said that hosting the games was a matter of honour for the nation and Delhi would prove competent in hosting it, but admitted some things might not be complete on time.

She informed that Fennel had visited the Thyagraj stadium and was satisfied with the preparations. He, though, was sceptical regarding the availability of power.

“Mike Fennel did pay me a visit about a month back, he spoke to me about just one thing, he said that, we hope power will be available. So, we said, “yes it would be available”. He had come at a time when there was a power crisis in Delhi. Apart from that, he spoke about Thyagraj, saying that we have been around and we are quite satisfied,” said Dixit.

The CGF General Assembly is due to meet in New Delhi early next month to assess the work a year ahead of the Oct 3-14 games. (ANI)

Natalizumab drug improves quality of life of MS patients

Washington, Sept 13 (ANI): A new study has found that multiple sclerosis patients taking Tysabri (Natalizumab) experienced a significant improvement in both their physical function and psychological well-being.

“The symptoms that an MS patient deals with on a daily basis result in significant psychological and physical effects that can adversely impact their quality of life,” said Dr William Stuart, medical director of the Multiple Sclerosis Center of Atlanta.

“In a previous pivotal trial, TYSABRI not only showed a reduction in relapse rates and disability progression, but also improved quality of life.

“Results from this observational study further demonstrate the impact of TYSABRI on improving MS patients’ well-being as reported by patients who live with this disease every day,” he added.

The study assessed the health outcomes from patients’ perspectives before starting TYSABRI and after the third, sixth and 12th infusions of TYSABRI.

After six TYSABRI infusions, patients reported statistically significant improvement in disease-specific quality of life (QoL), which measures the physical impact of MS in terms of mobility and self care, as well as the psychological impact of MS in terms of anxiety/depression.

The participants also scored higher in general health-related quality of life.

The findings were presented at the 25th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). (ANI)

War talks can boost older adults’ mental health

London, Sept 11 (ANI): Encouraging elderly to talk about old times can actually improve their memory and limit effects of dementia, finds a new study.

The research team led by Professor Catherine Haslam, at the University of Exeter, showed that ‘reminiscence therapy’ can significantly increase cognitive recall and agility of the mind by up to 12 per cent within six weeks.

During the study, the researchers recruited 73 people – aged between 70 and 90 and some with dementia – and split them into three groups.

The first group was made to sit around once a week in sets of five and reminisce about the old days such as childhood, weddings and family holidays, as well objects that could spark memories such as old-fashioned ink pots and hats.

After six weeks, the standard cognitive tests showed that the memory had improved by 12 per cent. Those suffering dementia saw an improvement of about eight per cent.

In contrast, the two other groups – one that was encouraged to play skittles – and another that was encouraged to have one on one chats showed very little improvement in their brain power.

“The people we were talking to were more than happy to bring up the war. It emerged as a very important part of their lives. As well as it improving their memory some people found it incredibly enjoyable,” the Telegraph quoted Prof Haslam, a neuropsychologist as saying.

“It doesn’t actually reverse dementia but it seems to make the most of their residual abilities,” she added.

Professor Alex Haslam, her husband, who was also carrying out research into social groups at the university, said the result were very significant.

“If you had a drug that could do that you would that you would make a lot of money. The drug in this case is the social group,” he said. (ANI)

New biomarker can bring rapid relief from major depression

Washington, Sept 11 (ANI): Scientists from University of California have identified a biomarker that can help accurately predict whether a particular drug will be effective in treating major depression.

During the study, the researchers measured changes in brain-wave patterns using quantitative electroencephalography (QEEG), a non-invasive, computerized measurement that recognizes specific alterations in brain-wave activity.

These changes precede improvement in mood by many weeks and appear to serve as a biomarker that accurately predicts how effective a given medication will be.

The new non-invasive test would help predict within a week whether a particular drug will be effective.

The added benefit of the biomarker test is that it ispainless and fast – about 15 minutes – and only involves the placement of six electrodes around the forehead and on the earlobes.

The researchers recruited a total of 375 people who had been diagnosed with major depressive disorder (MDD) and prescribed the antidepressant escitalopram, commonly known as Lexapro.

Then they examined a biomarker called the antidepressant treatment response (ATR) index – a specific change in brain-wave patterns.

The study showed that the ATR predicted both response and remission with an accuracy rate of 74 percent, much higher than any other method available.

The researchers also found that they could predict whether subjects were more likely to respond to a different antidepressant, bupropion, also known as Wellbutrin XL.

“Until now, other than waiting, there has been no reliable method for predicting whether a medication would lead to a good response or remission,” said Dr. Andrew Leuchter, professor of psychiatry at the Semel Institute for Neuroscience and Human Behavior at UCLA and lead author of the study.

“And that wait can be as long as 14 weeks. So these are very exciting findings for the patient suffering from depression,” said Leuchter.

The study results appear in the journal Psychiatry Research. (ANI)

Cooperative factories must help in ensuring sugar availability: Pawar

New Delhi, Sep 10(ANI): Agriculture Minister Sharad Pawar on Thursday urged cooperative sugar factories to play a more pro-active role and shoulder the responsibility of importing more raw sugar, not only for better utilization of their processing capacity, but also to fulfill their obligation of providing adequate and affordable sugar to the nation.

Addressing the 50th Annual Meeting of the General Body of National Federation of Cooperative Sugar Factories Ltd. here, Pawar said the government has already taken steps to assist sugar factories to further help sugarcane farmers to improve productivity as well as sucrose content in sugarcane by way of soft loans at four per cent per annum from SDF.

Pawar said that in view of the significant drop in sugarcane production, there isn’t for increasing sugarcane producing area immediately. The Central Government has also decided to give a one time short term loan assistance from SDF at four per cent per annum for the purchase of inputs like seed, fertilizers and pesticides.

“The loan given to the sugar factories has to be passed on to the farmers at not more than four per cent interest in cash or kind, before March 31, 2010,” Pawar added.

Pawar also requested the delegates to assess their individual capability and capacity to pay during 2009-10 sugar season and give remunerative price to the farmers, keeping in view the long term requirement of sugarcane.

This will encourage them to increase acreage under sugarcane as well as invest more in the sugarcane crop by way of inputs like fertilizers and pesticides, he added.

Pawar further requested the sugar factories to utilize modernization and expansion loans before investing in projects for utilizing the by-products.

The minister also talked about two important aspects -increased availability of sugarcane by way of improvement in productivity as well as recovery of sugar and controlling the cyclical nature of the sugarcane and sugar economy- which need to be addressed not only by the Government, but also by the sugar factories as well as the sugarcane farmers.

Stating that the country is reeling under pressure of high sugar prices along with lack of availability of sugar, not only in the domestic market, but also in the international market, Pawar discussed some unprecedented steps taken by the Government to supplement the domestic production of sugar and also ensure availability of sugar to the more vulnerable sections of the society.

He expressed hope that these steps would not only increase availability of sugar in the market within September, 2009, especially during the festival season, but also have a positive impact in controlling the sugar prices. (ANI)

New ‘Taliban killer’ sights for British troopers on Afghanistan frontier

London, Sep 9(ANI): After reports of British soldiers facing weapons’ shortage in the Afghanistan frontier, a range of new thermal weapons’ sights has been launched to enable soldiers to dominate the battlefield in Afghanistan.

According to reports, the British Ministry of Defence will buy almost 11,000 new sights for 150 million pounds, allowing the Army to equip 95 infantry companies of more than 100 men.

As part of the Ministry of Defence’s Future Integrated Soldier Technology (Fist) programme troops have been issued with a small glass prism-like sight, which project a red laser dot. It would help a soldier to quickly align the red dot on an enemy who is very close and hit him with guaranteed accuracy.

“This means the infantryman can pick up the enemy coming in. At night the enemy’s field craft has to be pretty adept because he has to remain in dead ground all the way up to your position and that is hard yards. This will allow us to dominate the night,” The Telegraph quoted Col Bill Pointing, a former battalion commander in charge of the project, as saying.

“This will allow the infantry to operate quicker, better, at longer range, at night and in difficult weather conditions,” he added.

It will provide improved protection, day and night surveillance and target acquisition, and assistance with navigation, command and control and battle preparation.

The new thermal weapons’ sights would also allow soldiers to conduct surveillance and engage targets in all weather and light levels, including zero light where normal night sights would be rendered ineffective.

“There is a considerable improvement in terms of us infantry engaging the Taliban at very close quarters in the villages of Afghanistan, especially at night time. It will help us to put very effective fire into them,” said Cpl Ciaran Hanna of the Irish Guards. (ANI)

Donkeys help five-year-old to “find his voice”

London, Sept 8 (ANI): Donkeys have helped a five-year-old boy suffering from selective mutism – a severe childhood anxiety disorder in which a person who is normally capable of speech is unable to speak in given situations -to “find his voice”.

Edward Wright was diagnosed with selective mutism at the age two.

His mother, Michelle, says she wasn’t worried initially but gradually she could not help noticing his silence.

The Daily Express quoted her as saying: “I was worried…He’d chat at home but if we were in a supermarket or at the doctors he wouldn’t say a word. It was as if he was scared of people he didn’t know hearing his voice.”

“At nursery he’d point to pictures of what he wanted to do each day rather than telling the staff. At first we thought he was just shy,” she added.

Although Edward’s family could not understand his behaviour, his speech therapist said his symptoms showed he was suffering from selective mutism.

Edward’s special coordinater suggested visits to a donkey-riding centre might help.

The Elisabeth Svendsen Trust (EST) For Children And Donkeys is situated on the outskirts of Leeds.

Every week nearly 150 children with disabilities and special needs spend time with the donkeys here.

Michelle explained: “The idea was that the games and activities Edward would do with the donkeys might help him overcome whatever was stopping him talking.”

Edward attended sessions at the centre last September and showed marked improvement in the weeks to follow.

Michelle said: “Gradually he became more confident…after a few weeks he began whispering commands into the donkeys’ ears. Later he would say instructions out loud to stop and start them while riding. It was lovely to see.”

She added: “At school he now talks to friends in the playground and he answers teachers when they ask questions. Every day he has an hour or two of speech therapy which also helps.

“Edward talks about the donkeys a lot, especially his favourite one Eeyore. The donkeys really have helped him find his voice.” (ANI)

Abilities India Pistons and Rings Ltd. awarded two gold trophies in ACMA awards

New Delhi, Sep 3 (ANI/Business Wire India): Abilities India Pistons and Rings Ltd. expert in manufacturing of Pistons and Piston Rings for 2 and4 stroke engines, for automobiles (mainly two / three wheelers) has won two Gold trophies, for excellence in Exports as well as in productivity and quality, in the golden Jubilee ceremony of ACMA awards (2008 – 2009).

Abilities India Pistons and Rings Ltd. is the largest manufacturer in India of two stroke pistons kits and is supplying it to USA, Europe and more than 35 countries through out the world.

Speaking on the occasion, Sunil Arora, Joint MD, AIP, stated that, “The real growth is going to start now. The market is ripe for the OEMs and there is tremendous scope to grow. With optimum capex and engineering excellence the company is gearing for the challenge. It was also a part of the ACMA Advance cluster which gave it the impetus to continuously strive for excellence.”

AIP is working as a leader for the manufacture of Pistons and Rings for automobiles (mainly two / three wheelers), chain saws, brush cutters, agriculture sprayers and compressors. AIP is a major OEM supplier for many reputed vehicle and engine manufactures of the country and overseas. AIP has to its credits the development of nearly 200 models of pistons for Chain Saws / Brush Cutters, which places it in a unique position to be a global supplier of Pistons to the OEM and after-markets as the necessary infrastructure for these models is readily available.

Abilities India Pistons and Rings Ltd. was established in the 1966 by R.S. Arora and converted into a limited company in 1995; the company has gone from strength to strength, overcoming many challenges on the way with great aplomb. It is an ISO/TS16949:2002 certified company, recognized EXPORT HOUSE as well as recipient of several AWARDS from EEPC and ACMA for excellence in Exports and Quality and Productivity.

Always keeping its employees first and firmly believing that the company’s success lies in its efficient and happy employees, the company continuously evolves practices that will ensure Total Employee Involvement. Stress is given to ‘all round improvement’ by making 5S, Poka Yoke, Kaizen, Deskilling and Talent development a part of its daily activities. (ANI)

Gogoi sets Sept.15 surrender deadline for Black Widow terror group

Guwahati, Sep.1 (ANI): Assam Chief Minister Tarun Gogoi on Tuesday set a September 15 deadline for the Dima Halam Daogah (Jewel) a.k.a. the “Black Widow” terror group to surrender.

Talking to reporters here, Gogoi said that the state government would not extend the cease-fire deadline set earlier for the group.

“No extension of cease-fire deadline with Black Widow beyond September 15,” Gogoi tersely said.

Gogoi’s tough stand was reiterated three days fater he had undertaken a four-hour whirlwind tour to Haflong, the headquarters of North Cachar Hills district where the DHD (J) is active.

Gogoi, who reviewed the ground situation in the insurgency-hit district and held key meetings with top administration and security officials, stressed that the DHD (J) must stop all kinds of insurgent activities and extortion campaigns as a precondition to talks.

He said “the group must also hand over all the arms before coming forward for talks.” The arms will be deposited in an armoury, to be supervised by both police and the outfit.

The Calcutta Telegraph had earlier quoted Gogoi, as saying that the government had been receiving feelers from the DHD (J), expressing the outfit’s willingness to sit for a dialogue. But it would not accept any such offer unless the outfit’s leadership, and not a section of its cadres, came forward for talks.

DHD (J) chief Jewel Gorlosa, was arrested along with another leader, Partho Warisa, from Bangalore in June this year, forcing the outfit’s lower ranked cadres to declare a unilateral cease-fire.

Dispur, however, continued its operation against the outfit. The unilateral ceasefire, declared by the DHD (J) in North Cachar Hills for three months, will expire on September 7.

Gogoi also made it clear that Dispur would not agree to the demand of renaming North Cachar Hills into Dima Hajao Raji and that the district would not suffer any vivisection in future.

The chief minister expressed satisfaction over the “visible improvement” in law and order in the district in the past three months.

He assured tribal leaders that measures would be taken to usher in peace, rehabilitate violence-hit people and chalk out a special development package for the district. (ANI)

Tata Motors suffer Q1 loss, but confident of improvement

Mumbai, Sep 1 (ANI): Tata Motors, India’s largest vehicle maker have posted a consolidated loss for its fiscal first quarter, but remained confident about the prospects of its loss-making Jaguar and Land Rover (JLR) unit.

This was disclosed by the C Ramakrishnan, Chief Financial Officer at a press conference that was also addressed by Ravi Kant, Vice Chairman and Prakash Telang, Managing Director of the company here on Monday.

The company, which controls about 60 percent of the world’s fifth-biggest truck and bus market, said that increased borrowing to support investments and new product development caused an increase in depreciation and interest costs.

It said JLR unit’s sales fell about 52 percent in the quarter from a year ago due to adverse global market conditions.

The company is eyeing some support from the commercial banks to meet the crisis.

“We are working on to tie up our working facilities with commercial banks for Jaguar and Land Rover (JLR)…this has been put in place, some work is still going on which would be finalise in next few weeks,” said Ramakrishnan.

The company reported 3.29 billion rupees consolidated loss for April-June.

In the year-ago quarter, Tata Motors posted a net profit of 7.2 billion rupees, but said the figures were not comparable as the previous period contained JLR numbers only for June 2-30. Tata said JLR made a loss before tax of 62 million pounds during the fiscal first quarter. JLR sold 35,900 units during the quarter, up from 32,600 in the March quarter.

In July, Tata Motors reported a standalone net profit of 5.14 billion rupees for its Indian operations. But officials hoped that market would recover despite a weal monsoon.

“I can say that things would have been better, but the monsoon has not been so good that caution optimism but we still believe that things would be slightly better in coming time,” said Prakash Telang, Managing Director, Tata Motors.

Auto sales in India have been rising on an improving economy, easier finance and new launches, including Tata Motor’s Nano, the world’s cheapest car, which hit the roads in July.

The company’s consolidated debt at the end of June stood at 240 billion rupees. The company has said it would look at capital raising at an appropriate time to deleverage its balance sheet. (ANI)

Force India, Fisichella on pole position for Belgian Grand Prix

Spa-Francorchamps (Belgium), Aug 29(ANI): Formula One Racing team Force India, which is backed by liquor baron Vijay Mallya, on Saturday claimed the pole position in qualifying session for Sunday’s Belgian Grand Prix, as Giancarlo Fisichella exhibited an incredible performance to come on top.

It was Force India team’s first-ever pole and the fourth for Fisichella, as he recorded a remarkable qualifying time with a lap of 1 minute, 46.308 seconds to start the Belgian Grand Prix at the front of the grid.

“It’s unbelievable. I didn’t expect to be on pole. It’s amazing. It’s fantastic. I’m so happy. Pole position! Is it true?,” Fisichella said.

“I need to thank the team because they did a fantastic job. I’m really, really happy – and really confident for tomorrow!,” he added.

Meanwhile, Toyota driver Jarno Trulli will start second and BMW Sauber’s Nick Heidfeld will start third following a qualifying session that produced many surprises.

Force India has recently introduced a series of updates to Fisichella and Adrian Sutil’s cars, which showed signs of improvement at last weekend’s European Grand Prix, where both drivers ran well. (ANI)

New Cytotron treatment effective in treating cancer patients in Bangalore

Bangalore, Aug 28 (ANI): The new Cytotron treatment that includes use of radio frequency, high power non-ionizing, non-thermal electromagnetic waves instead of high frequency radiation has emerged as a popular therapy for cancer patients in Bangalore.

Developed by Rajah Vijay Kumar of India in 1987, the Cytotron device helps in tissue regeneration, degeneration and repair for the purposes of treating several chronic or degenerative diseases such as cancer and arthritis.

The treatment modality is non-invasive, painless and free from side effects.

Clinical test have shown that Cytotron is very effective in curing certain conditions such as a damaged knee by regenerating the cartilage tissue.

Dr. Nayar of Ojus Health Care, Bangalore, said that Cytotron treated patients have survived for a longer period than patients treated by other methods.

“When there is hardly any chance of survival after one year, those kind of patients have been taken for the clinical trials and from that we found that as against the expected 0-5 per cent may be surviving after one year. We got a very interesting and encouraging result of may be up to 50 per cent in different series. So 40-50 per cent to even may be little more per cent of people are able to survive year or more,” said Dr. Nayar.

Dr. Nayar also said that the treatment is safe and healthy cells are not affected in any way.

“This is something, which is very unique. It’s safe. It’s absolutely harmless and with this machine, we can target it to the exact depth in the body tissue,” said Dr. Nayar.

One such success story of Cytotron treatment is that of Abraham, a surgeon-cum-cancer patient.

Abraham, who is a patient of arthritis, has been undergoing the treatment for the past 15 days. He said that he has found improvement in his conditions and is now able to walk without any pain.

“I felt the difference, the swelling came down and the pain also reduced. I felt some sort of relief in that one. So the actual duration day told 21 days, so after 15 days of treatment, it’s comfortable and my all the symptoms got relieved. I am finding improvement in my condition,” said Abraham.

Doctors consider Cytotron as a useful method to treat cancer. By Shweta ANI)

Scientists uncover vulnerable enzyme that can be targeted to kill dangerous pathogens

Washington, August 28 (ANI): A collaborative study conducted by researchers from three institutions in the U.S. has shown that an enzyme, which is essential to many bacteria, can be targeted to kill dangerous pathogens.

Experts at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have also identified chemical compounds that can inhibit this enzyme, and suppress the growth of pathogenic bacteria.

Writing about their study in the journal Chemistry and Biology, the researchers say that their findings are essential to develop new broad-spectrum antibacterial agents to overcome multi-drug resistance.

Dr. Andrei Osterman, an associate professor in Burnham’s ioinformatics and Systems Biology program, targeted the acterial nicotinate mononucleotide adenylyltransferase (NadD), an essential enzyme for nicotinamide adenine dinculeotide (NAD) biosynthesis, which has many crucial functions in nearly all important pathogens.

The bacterial NadD differs significantly from the human enzyme.

“It’s clear that because of bacterial resistance, we need new, wide-spectrum antibiotics. This enzyme is indispensable in many pathogens, so finding ways to inhibit it could give us new options against infection,” said Dr. Osterman.

The research team used a structure-based approach to search for low-molecular-weight compounds that would selectively inhibit bacterial NadD, but not the human equivalent, by screening, in silico, more than a million compounds.

In their experiments, they tested the best predicted compounds against Escherichia coli and Bacillus anthracis (anthrax), which led them to a handful of versatile inhibitory chemotypes, which they explored in detail.

Using protein crystallography, a 3D structure of the enzyme in complex with one of the inhibitors was solved providing guidelines for further drug improvement.

“This is proof-of-concept that NadD is a good target to create antibacterial agents. This knowledge will be useful for both biodefense and public health. The next step is to find better inhibitors. We do not have a silver bullet yet, but we are certainly hitting a golden target,” said Dr Osterman.

The research was supported by a grant from the National Institute of Allergy and Infectious Diseases. (ANI)

Bariatric surgery can eliminate diabetes symptoms

London, Aug 28 (ANI): Weight-loss surgery can help eliminate the symptoms of type 2 diabetes in nearly 80 percent patients, an international study has found.

The research team led by Professor Henry Buchwald of the Department of Surgery at the University of Minnesota, Minneapolis, observed almost 135,000 patients for the study.

The findings concluded that 78 per cent patients had a “complete resolution” of diabetes for up to two years post-surgery, while 87 either saw resolution or noted an improvement in their condition, reports Timesonline.

Type 2 diabetes is common to obese people and occurs when the body stops producing or using insulin, the hormone that maintains the sugar level in blood.

Losing weight can help the body to efficiently use available insulin, and thus prevent kidney failure, nerve damage and eye problems.

The weight-loss surgery, medically known as the bariatric surgery, or the gastric-band operation, fits a band around the upper part of the stomach, restricting the amount people can eat before feeling full. Though the operation can benefit diabetes patients, it is advised only for the very obese, who’ve failed to lose weight otherwise.

But charity Diabetes UK is a little sceptical about the findings of the research.

Zoë Harrison, care adviser for the charity, said: “Although the data shows good results from bariatric surgery, it must be remembered that any surgery carries serious risks.

“Bariatric surgery should be considered only as a last resort. It can lead to dramatic weight loss, which in turn may result in a reduction in people taking their type 2 diabetes medication, and even in some people needing no medication at all. This does not mean type 2 diabetes has been cured.

“These people will still need to eat a healthy, balanced diet and be physically active to manage their diabetes.” (ANI)

Bariatric surgery can eliminate diabetes symptoms

London, Aug 28 (ANI): Weight-loss surgery can help eliminate the symptoms of type 2 diabetes in nearly 80 percent patients, an international study has found.

The research team led by Professor Henry Buchwald of the Department of Surgery at the University of Minnesota, Minneapolis, observed almost 135,000 patients for the study.

The findings concluded that 78 per cent patients had a “complete resolution” of diabetes for up to two years post-surgery, while 87 either saw resolution or noted an improvement in their condition, reports Timesonline.

Type 2 diabetes is common to obese people and occurs when the body stops producing or using insulin, the hormone that maintains the sugar level in blood.

Losing weight can help the body to efficiently use available insulin, and thus prevent kidney failure, nerve damage and eye problems.

The weight-loss surgery, medically known as the bariatric surgery, or the gastric-band operation, fits a band around the upper part of the stomach, restricting the amount people can eat before feeling full. Though the operation can benefit diabetes patients, it is advised only for the very obese, who’ve failed to lose weight otherwise.

But charity Diabetes UK is a little sceptical about the findings of the research.

Zoë Harrison, care adviser for the charity, said: “Although the data shows good results from bariatric surgery, it must be remembered that any surgery carries serious risks.

“Bariatric surgery should be considered only as a last resort. It can lead to dramatic weight loss, which in turn may result in a reduction in people taking their type 2 diabetes medication, and even in some people needing no medication at all. This does not mean type 2 diabetes has been cured.

“These people will still need to eat a healthy, balanced diet and be physically active to manage their diabetes.” (ANI)