Genes behind ageing process identified

London, May 26 (ANI): British scientists have identified genes that control the ageing process.

The finding could lead to new drugs to prevent illnesses from heart disease to Alzheimer’s.

In the laboratory, researchers have found that mutations could extend the lifespan of animals such as worms, fruit flies and mice, and appear to play the same role in humans.

Professor Linda Partridge, director of the Institute of Healthy Ageing at University College London, has said that the research could help in the treatment or delay of many diseases simultaneously with medication.

She added that tackling the very causes of ageing, instead of treating the symptoms, could be the best way of dealing with the diseases that result from it.

In her opinion, such scientific advances are offering up hope to improve health during ageing in humans and inspiring a new wave in ageing research.

“Research on the diseases associated with ageing is generally done by separate communities of research workers who read different journals, attend different conferences and generally do not communicate with each other,” The Telegraph quoted Partridge as saying.

She added: “But by tacking the causes of ageing itself we could treat, or at least delay, a broad spectrum of conditions simultaneously.”

Drugs, which inhibit the nutrient pathways in humans, could replicate the effects of a healthy diet.

And thus, they can act not only to increase lifespan but also to target a broad range of ageing related diseases such as cardiovascular disease, cancers, diabetes and Alzheimer’s.

Partridge said that the research indicates a new approach to the treatment of age-related conditions.

“The major burden of ill health is in the older section of the population. The new discoveries about ageing have raised the prospect of increasing the number of years that people enjoy in good health, with broad-spectrum preventative medicines for the diseases of ageing,” said Linda.

She will present the findings at a public lecture at the Royal Society in London. (ANI)

Centenarians’ offspring show personality traits linked with healthy ageing, longevity

Washington, April 4 (ANI): Scientists have found that the children of centenarians generally possess certain personality traits that are associated with healthy ageing and longevity.

Researchers from Boston University School of Medicine’s (BUSM) New England Centenarian Study used questionnaires to obtain measures of the personality traits for neuroticism, extraversion, openness, agreeableness, and conscientiousness were obtained from 246 unrelated offspring of centenarians – 125women and 121men – with an average age of 75.

The researchers said that both the male and female offspring of centenarians scored in the low range of published norms for neuroticism and in the high range for extraversion.

They further said that the women also scored comparatively high in agreeableness.

Both sexes scored within normal range for conscientiousness and openness, and the men scored within normal range for agreeableness, the team added.

According to the researchers, personality traits in the offspring of centenarians appear to have distinctive characteristics that may have important implications for their longevity.

“Interestingly, whereas men and women generally differ substantially in their personality characteristics, the male and female offspring tended to be similar, which speaks to the importance of these traits, irrespective of gender, for health aging and longevity,” Dr. Thomas Perls, director of the New England Centenarian Study.

“It’s likely that the low neuroticism and higher extraversion will confer health benefits for these subjects.

“For example, people who are lower in neuroticism are able to manage or regulate stressful situations more effectively than those with higher neuroticism levels. Similarly, high extraversion levels have been associated with establishing friendships and looking after yourself.

“These findings suggest that personality is an important characteristic to include in studies that assess genetic and environmental determinants of longevity. Such studies are currently underway,” he added.

The study, conducted in collaboration with scientists from the National Institute on Aging, appears on-line in the Journal of the American Geriatrics Society. (ANI)