Early daycare leads to smarter teens

Washington, May 15 (ANI): Teenagers who receive better child care during early years fair slightly higher on measures of academic and cognitive achievement compared to their counterparts who don’t, a new research indicates.

A long-running study funded by the National Institutes of Health shows that teens who had spent the most hours in child care in their first 4½ years reported a slightly greater tendency toward impulsiveness and risk-taking at 15 than did peers who spent less time in child care.

The study is the first to track children for a full decade after they left childcare.

“Previous findings from the study indicate that parents appear to have far more influence on their child”s growth and development than the type of child care they receive,” said James A. Griffin, Ph.D., deputy chief of the Child Development and Behavior Branch, at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the NIH institute that funded the study, “The current findings reveal that the modest association between early child care and subsequent academic achievement and behavior seen in earlier study findings persists through childhood and into the teen years.”

The 1,364 youth in the analysis had been evaluated periodically since they were 1 month of age, as part of the NICHD Study of Early Child Care and Youth Development (SECCYD), the largest, longest running and most comprehensive study of child care in the United States.

The families that participated in the study were from diverse geographic, demographic, economic and ethnic backgrounds.

From 1 month of age through sixth grade, children were evaluated at least annually on tests of cognitive and academic progress. When the students were 15, the researchers tested the students” academic achievement and, using a questionnaire, had the students evaluate their own behaviors. These included measures of behavioral problems (acting out in class); impulsivity (acting without thinking through the consequences); and risk taking (engaging in behaviors that might harm themselves or others).

A new finding that emerged at age 15 was that youth who had spent more time in quality childcare as young children reported fewer acting-out behavior problems as teenagers.

“These results underscore the importance of interaction between children and their daytime caregivers,” said first author Deborah Lowe Vandell, Ph.D., professor and chair of the Department of Education at University of California, Irvine. “We”re seeing enduring effects of the quality of staff-child interaction.”

The study also indicated that the results were consistent amongst boys and girls, and to find out if childcare could have benefits for children from economically disadvantaged homes, the researchers created a risk index with such factors as family income, the mother”s level of education and others.

“High quality child care appears to provide a small boost to academic performance, perhaps by fostering the early acquisition of school readiness skills,” said James A. Griffin, Ph.D., deputy chief of the NICHD Child Development & Behavior Branch. “Likewise, more time spent in child care may provide a different socialization experience, resulting in slightly more impulsive and risk-taking behaviors in adolescence. These findings underscore the importance of studying the linkages between early care and later development.”

The study results appear in the May/June issue of the journal Child Development. (ANI)

Co-ordination between home, preschool, school key to child’s progress

Washington, May 14 (ANI): Co-ordination between home, preschool, and school is fundamental to child’s progress, a new study claims.

Robert Crosnoe, associate professor of sociology at the University of Texas at Austin, analysed more than 1,300 children living in 10 locations in the United States to reach the conclusion.

The kids were followed from birth in the Study of Early Child Care and Youth Development.

It was carried out under the auspices of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) by researchers at the University of Texas at Austin, Tufts University, the University of North Carolina at Chapel Hill, the University of California, Irvine, the University of Virginia, and the NICHD Early Child Care Research Network.

Crosnoe said: ” The study has implications for policy as Congress reauthorizes the No Child Left Behind Act. Our findings point to the importance of improving coordination among parents, preschool classrooms, and elementary schools to boost children”s achievement.”

The experts evaluated children”s homes and child care/preschool settings when the children were 4-1/2 years old, studied their first grade classrooms, and evaluated reading and math test scores through fifth grade.

In doing so, they gauged whether the links between various combinations of cognitive stimulation and children”s achievement were simply due to the socioeconomic circumstances of the children”s families, or whether children from different socioeconomic backgrounds got more or less, academically, from each combination.

Crosnoe added: “The ultimate payoff of attempts to improve one context of early childhood depends in part on whether related contexts are improved, too.”

Moreover, even though children from advantaged families are more likely to experience this convergence of support for learning across the contexts of their lives, the study found that low-income children may benefit more from it.

Crosnoe further briefed: “Helping children, especially those from poor families, get off to a good start in elementary school has become a major focus of education policy. These policy interventions typically target one setting—the home, preschool, or elementary school—but rarely the intersection of all three.”

He ended: “To do so, policymakers must put renewed focus on the home-preschool partnerships often advocated by early intervention programs and the family-school partnerships advocated by No Child Left Behind, the Elementary and Secondary Education Act.” (ANI)

Parent involvement vital in elementary years

Washington, May 14 (ANI): Children whose parents are more involved across elementary school have fewer problem behaviors and better social skills, but that children”s academics aren’t affected, according to a new study.

The study carried out under the auspices of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), was based on information about more than 1,300 children from 10 U.S. cities who were followed from birth to fifth grade.

The study aimed at learning how parent involvement affects children”s academic, social, and emotional well-being in elementary school. The children studied were mostly White and about evenly divided by gender.

According to the findings, parents’ involvement – visits to the school, encouraging educational progress at home, remedied children”s problem behaviors (including both aggressive and disruptive behaviours as well as anxiety and depression. At the same time, their so-called pro-social skills (such as cooperation and self-control) improved.

Their involvement however, did not affect achievement possibly because it wasn’t specific to academic performance of the child.

“The study shows that parents continue to wield considerable influence on children”s development through elementary school,” according to the researchers. “Therefore, the study has implications for policies to encourage involvement.”

The study is published in the May/June 2010 issue of the journal Child Development. (ANI)

Obese kids are bullied more

Washington, May 3 (ANI): A new study has shown that obese children are more likely to be bullied regardless of gender, race, socioeconomic status, social skills or academic achievement.

A research team, led by Julie C. Lumeng, assistant professor in the Department of Pediatrics and Communicable Diseases at the University of Michigan”s C.S. Mott Children”s Hospital, studied 821 children who were participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Study of Early Child Care and Youth Development.

These children were recruited at birth in 10 study sites around the country.

The researchers evaluated the relationship between the child”s weight status and the odds of being bullied as reported by the child, mother, and teacher.

The study accounted for grade level in school, gender, race, family income-to-needs ratio, racial and socioeconomic composition of the school, and child social skills and academic achievement as reported by mothers and teachers.

The researchers found that obese children had higher odds of being bullied no matter their gender, race, family socioeconomic status, school demographic profile, social skills or academic achievement.

The authors concluded that being obese, by itself, increases the likelihood of being a victim of bullying. Interventions to address bullying in schools are badly needed, Lumeng added.

The study will be published in the June issue of the journal Pediatrics. (ANI)

Self-regulation can help at-risk children perform better at academics

Washington, April 28 (ANI): Self-regulation is the key to academic success for at-risk children, a new American study has found.

Self-regulation refers to children”s ability to control their behaviour and impulses.

The study was conducted by then-Oregon State University graduate student Michaella Sektnan, who did the research as her master”s thesis working with Megan McClelland, an associate professor at OSU.

Sektnan is now a faculty research assistant for OSU Extension Family and Community Health.

For her paper, which will appear in a fall edition of Early Childhood Research Quarterly, Sektnan used data on 1,298 children from birth through the first grade from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development.

“Family risk” in the data was defined by ethnic minority status, low maternal education, low family income and chronic depressive symptoms in the mother.

Sektnan said: “We know that these risk factors can lead to a gap in academic achievement.

“The relationship to risks such as poverty, ethnic status, and maternal education has been well-documented. What we wanted to know was, controlling for these factors, does self-regulation make a difference?”

It turns out the answer to that question is yes.

Controlling for these risk factors, Sektnan found that children whose parents and teachers reported that they had strong self-regulation in preschool and kindergarten did significantly better on math, reading and vocabulary at the end of first grade.

Sektnan said: “For all outcomes, higher self-regulation was related to higher reading, math and vocabulary, regardless of which risk factor was present.

“This builds on the increasing body of knowledge about the need to develop self-regulation skills in young children.”

To give an example, McClelland points to the test scores of the children in this national survey.

At-risk children with stronger self-regulation in kindergarten scored 15 points higher on a standardized math test in first grade, 11 points higher on an early reading test, and nearly seven points higher on a vocabulary test than at-risk children with weaker self-regulation.

McClelland said: “These were pretty impressive increases in children”s achievement.

“I”m a proponent of building self-regulation in children but even for me, these results were surprising. The discrepancy between these children, tested at a very young age, and their academic scores compared to their peers who were not as able to regulate their behaviour was larger than we anticipated.”

She went on: “Obviously, these issues – poverty, educational status, maternal depression – are extremely serious and must be addressed.

“But we now know that we can also help children be successful by teaching them how to self-regulate.”

McClelland added: “Self-regulation is not just about compliance or being obedient.

“It”s about a very basic, but very necessary skill: being able to listen and pay attention, think, and then act. The message to parents may be to put down the flash cards and see if another approach, like playing a simple game of ”Simon Says” works better.” (ANI)

Strict control over kids’ diet not linked with childhood weight gain

Washington, May 27 (ANI): Strict maternal control over eating habits during early childhood-such as determining how much a child should eat and coaxing them to eat certain foods-might not have any connection with future weight gain in kids, according to a study.

The study suggests that such behaviour may be a response to concerns over a child’s increasing weight.

“Our findings suggest that controlling maternal feeding practices probably do not cause increased weight gain, as some previous studies have proposed. In fact, some degree of control may actually be beneficial in helping certain children maintain their weight,” said lead author Dr. Kyung E. Rhee, a researcher with the Weight Control and Diabetes Research Center at The Miriam Hospital.

Many studies have linked controlling or restrictive feeding practices with disinhibited child eating, increased caloric intake and excessive weight gain.

This prompted many experts to recommend that parents avoid these overly restrictive behaviours when helping children control their weight.

However, in the latest study, the researchers have found that the relationship between controlling feeding practices and child weight has been inconsistent and has not conclusively determined whether these practices cause, or are a consequence of, weight gain.

The researchers examined the data of 789 children (equal number of boys and girls), who participated in the National Institute of Child Health and Human Development’s Study of Early Child Care and Youth Development.

Child heights and weights were obtained at ages 4, 7 and 9 and changes in body mass index (BMI) were measured between 4-7 years and 7-9 years.

The researchers also measured maternal feeding practices at each age interval by asking mothers the question: “Do you let your child eat what he/she feels like eating?”

It was found that in boys, increases in restrictive feeding practices between the ages of 4 and 7 were linked with a decreased risk of increased BMI by the time the boys were 7-9 years old.

However, when it came to girls, mothers seemed to increase their control when they thought that their daughters had gained significant amounts of weight between the ages of 4 and 7.

“Our findings mirror those of other studies that have found that parents are much less likely to recognize or be concerned about the overweight status of sons compared to daughters. These behaviours may represent a sensitivity to societal values that girls should be slim while boys have a physical or social advantage in being larger,” said Rhee.

Thus, the researchers have said that restrictive feeding practices may actually be necessary for some children to help regulate their food intake, promote healthier eating habits and limit excessive weight gain.

The study has been published online in the journal Obesity. (ANI)

Key proteins linked to ovulation identified

Washington, May 15 (ANI): Researchers from the National Institutes of Health have identified two proteins that play a vital role in ovulation process.

The discovery, researchers hope, would help in treating infertility resulting from a failure of ovulation. It will also aid in developing new means to prevent pregnancy by preventing the release of the egg.

The proteins, called ERK1 and ERK2, appear to bring about the maturation and release of the egg.

“Ovulation results from a complex interplay of chemical sequences,” said Dr Duane Alexander, director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

“The researchers have identified a crucial biochemical intermediary controlling the release of the egg.

“The finding advances our understanding and may one day contribute to new treatments for infertility as well as new ways to prevent pregnancy from occurring,” Alexander added.

ERK1 and ERK2 are a critical nexus between the surge in luteinizing hormone and ovulation, said Dr Louis V. De Paolo chief of the NICHD Reproductive Sciences Branch.

“This is a key chemical pathway that affects not only ovulation, but egg cell maturation and granulosa cell differentiation into luteal cells,” Dr. De Paolo added.

Luteinizing hormone is a hormone produced by the anterior pituitary gland.

Previously, researchers did not know how luteinizing hormone triggered the ovary’s release of the egg and the production of progesterone by the granulosa cells.

In the current study, the researchers discerned that luteinizing hormone appears to signal the release of the ERK 1 and ERK 2 proteins.

“We’re still at the tip of the iceberg. We need to understand it all,” said De Paolo said. (ANI)

Now, ‘DNA patches’ to treat canine form of muscular dystrophy

Washington, Mar 17 (ANI): Researchers have developed a new technique in which DNA patches are used to treat dogs with the canine version of Duchenne muscular dystrophy, a paralysing and often fatal disease of muscles.

Called “exon skipping”, the technique uses tailor-made snippets of DNA-like molecules as molecular “patches”, which cover up mutant DNA sequences that code for making an important muscle protein.

The mutant sequences occur in portions of the gene known as exons, which contain the information needed to make the muscle protein.

By covering up the mutant regions, the DNA patches allowed the dogs to make an imperfect-but functional-version of the protein, and significantly improve their muscle functioning.

The researchers say that their findings have shown that the DNA patches could be delivered by injection throughout the entire body in a much larger animal than a mouse, raising the possibility that they might be successfully delivered into the human body as well.

The current study also represents an advance over the earlier efforts in that it was able to use several different kinds of DNA patches.

A combination of different patches, known as a cocktail, would be needed to treat most of the human cases of the disease, which can involve many different exons.

The canine version of Duchenne muscular dystrophy occurs naturally in dogs, and affects the same gene that is affected in the human form of the disease.

“This is a promising finding. It’s an important step toward realizing the goal of developing a treatment that could alleviate the symptoms of this disorder,” said Dr. Duane Alexander, director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

The study was published online in the Annals of Neurology. (ANI)

Women’s low vitamin B12 levels up their kids’ risk of neural tube defects

Washington, Mar 2 (ANI): Women with low blood levels of vitamin B12 shortly before and after conception may have children with increased risk of a neural tube defect, according to a new study.

Researchers at the National Institutes of Health, Trinity College Dublin, and the Health Research Board of Ireland have found that women with the lowest B12 levels had five times the risk of having a child with a neural tube defect as compared to those with the highest B12 levels.

Also, the study revealed that women who consumed little or no meat or animal-based foods were the most likely group of women to have low B12 levels, along with women who had intestinal disorders that prevent them from absorbing sufficient amounts of B12.

Neural tube defects are a class of birth defects affecting the brain and spinal cord.

It is already known that taking another nutrient, folic acid, during the weeks before and after conception can reduce a woman’s chances of having a child with a neural tube defect. Folic acid is the synthetic form of the vitamin folate.

“Vitamin B12 is essential for the functioning of the nervous system and for the production of red blood cells,” said Dr. Duane Alexander, director of the National Institute of Child Health and Human Development.

He added: “The results of this study suggest that women with low levels of B12 not only may risk health problems of their own, but also may increase the chance that their children may be born with a serious birth defect.”

For the study, the researchers analysed stored blood samples originally collected during early pregnancy from three groups of Irish women between 1983 and 1990. During that time, pregnant women in Ireland rarely took vitamin supplements.

They explained that the lack of routine vitamin supplementation would enable them to identify a sufficient number of women with low Vitamin B12 to conduct their analysis.

As low folate levels are a known risk factor for neural tube defects, the researchers used statistical techniques to evaluate the role of Vitamin B12 independently of the role of folate.

It was found that women with low B12 concentrations (estimated at less than 250 ng/L, before pregnancy) had 2.5-3 times the risk of having a child with a neural tube defect compared to those with higher levels.

Women with levels in the deficient range (0-149 ng/L ) were at the highest risk: 5 times that of women with higher levels.

Scientists said that it is not known how B12 and folate might interact to influence the formation of the neural tube, the embryonic structure that gives rise to the spine and brain.

They pointed out that the two vitamins are jointly involved with several key biochemical reactions, as well as with the synthesis of DNA.

Lack of either Vitamin B12 or folate in any of these chemical processes theoretically could increase the risk of a neural tube defect.

An NICHD author of the paper said that as Vitamin B12 comes from foods of animal origin, women who adhere to a strict vegan diet may be at risk for a B12 deficiency.

He added it is advisable for women with digestive disorders that interfere with the absorption of foods to consult a physician before getting pregnant, to make sure they are receiving adequate amounts of B12.

“Our results offer evidence that women who have adequate B12 levels before they become pregnant may further reduce the occurrence of this class of birth defects,” wrote the authors.

The study appears in the journal Pediatrics. (ANI)