MARTINSRIED, GERMANY and MUNCHEN, GERMANY, Jul 06
(MARKET WIRE) —
MorphoSys AG / MorphoSys Receives Research Grant to Advance Anti-CD38
Cancer Program MOR202 and Explore Relevant Biomarkers processed and
transmitted by Hugin AS. The issuer is solely responsible for the content
of this announcement.
Project is Part of Munich’s Cluster Initiative “m4 – Personalized Medicine
and Targeted Therapies”
MorphoSys AG (FSE: MOR; Prime Standard
Segment, TecDAX) announced today that it has been awarded a grant by the
German Federal Ministry of Education and Research, BMBF. The funding of
approximately EUR 1 million supports MorphoSys in accelerating the
development of its HuCAL-based cancer program MOR202 into clinical
development for the treatment of multiple myeloma. As part of the
program, the Company plans to explore relevant biomarkers for the
anti-CD38 approach in collaboration with Klinikum rechts der Isar, the
university hospital of Munich Technical University. The program is part
of Munich’s biotechnology initiative “m4 – Personalized Medicine and
Targeted Therapies – A New Dimension in Drug Development in the Munich
Region”, which this year received high-tech cluster status in a German
government funding competition.
MOR202 is a fully human, HuCAL antibody directed against CD38, a membrane-
bound glycoprotein that is a promising therapeutic target for the
treatment of multiple myeloma and certain leukemias. In pre-clinical
studies, MOR202 effectively killed cancer cells from primary patient
tumor material and certain hematologic cancer cell lines. Furthermore,
preclinical efficacy was shown by demonstrating inhibition of tumor
growth in SCID-mouse xenograft tumor models. The program is expected to
move into clinical trials in Q1 2011.
“We believe that MOR202 has a very competitive profile and distinct
advantages over similar programs in the industry. As part of the research
program with Klinikum rechts der Isar we plan to explore certain
biomarkers for this new therapeutic approach, thereby further
differentiating our program,” commented Dr. Arndt Schottelius, Chief
Development Officer of MorphoSys AG. “This grant supports the MOR202
program, for which we are on track to file a clinical trial application
in Europe before the end of 2010.”
About MorphoSys:
MorphoSys is an independent biotechnology company that develops novel
antibodies for therapeutic, diagnostic and research applications. The
Company’s HuCAL technology is one of the most powerful methods available
for generating fully human antibodies. By successfully applying this and
other proprietary technologies, MorphoSys has become a leader in the
field of therapeutic antibodies, one of the fastest-growing drug classes
in human health-care. Through its alliances with some of the world’s
leading pharmaceutical companies, MorphoSys has created a pipeline of
more than 60 drug candidates. The Company is expanding its drug pipeline
by adding new partnered programs, and by building a portfolio of
fully-owned therapeutic antibodies. For its proprietary portfolio, the
Company is focused on the areas of oncology and inflammation. Its most
advanced program MOR103, a first-in-class, fully human antibody against
GM- CSF, is currently tested in a Phase Ib/IIa trial in rheumatoid
arthritis patients. Via its business unit AbD Serotec, MorphoSys is
expanding the reach of its technologies in the diagnostics and research
markets. MorphoSys is headquartered in Munich, Germany and listed on the
Frankfurt Stock Exchange under the symbol “MOR”. For further information,
visithttp://www.morphosys.com/
HuCAL(R), HuCAL GOLD(R), HuCAL PLATINUM(R), CysDisplay(R) and RapMAT(R)
are registered trademarks of MorphoSys.
This communication contains
certain forward-looking statements concerning the MorphoSys group of
companies. The forward-looking statements contained herein represent the
judgment of MorphoSys as of the date of this release and involve risks
and uncertainties. Should actual conditions differ from the Company’s
assumptions, actual results and actions may differ from those anticipated.
MorphoSys does not intend to update any of these forward-looking
statements as far as the wording of the relevant press release is
concerned.
For more information, please contact:
MorphoSys AG
Dr. Claudia Gutjahr-Loeser
Head of Corporate Communications & IR
Tel: +49 (0) 89 / 899 27-122
Mario Brkulj
Senior Manager Corporate Communications & IR
Tel: +49 (0) 89 / 899 27-454
Jessica Kulpi
Specialist Corporate Communications & IR
Tel: +49 (0) 89 / 899 27-332
investors@morphosys.com
[HUG#1429636]
Press Release:
http://hugin.info/130295/R/1429636/376667.pdf
This announcement is
distributed by Thomson Reuters on behalf of Thomson Reuters clients.
The owner of this announcement warrants that:
(i) the releases contained herein are protected by copyright and other
applicable laws; and
(ii) they are solely responsible for the content, accuracy and originality
of the information contained therein.
All reproduction for further distribution is prohibited.
Source: MorphoSys AG via Thomson Reuters ONE
Copyright 2010, Market Wire, All rights reserved.