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Genes controlling insulin ‘alter’ body clock

Washington, Sept 18 (ANI): Scientists at University of California, San Diego have identified certain insulin-regulating genes that can also alter the timing of the body clock.

They said that the findings can lead to new approaches to treating disorders such as metabolic syndrome that can result, at least in part, from chronic disruption of the sleep-wake [...]

Stem cell transplantation may correct rare genetic disorder in kids

Washington, Sep 18 (ANI): Scripps Research Institute scientists have offered new hope for parents whose children suffer from the rare genetic disorder ‘cystinosis’ by showing through an experiment on mice that stem cell transplantation [...]

Gene linked to male infertility identified

Washington, Sept 16 (ANI): Scientists from Virginia Commonwealth University have identified a gene that may contribute to male infertility.

The research team hopes that the new findings would lead to new approaches to male contraception.

Sperm are produced in the testicles through a three-step process called spermatogenesis.

During the final stage, known as spermiogenesis, a lot of [...]

Master gene that switches on disease-fighting cells identified

London, Sep 14 (ANI): British scientists have identified the master gene, called E4bp4, that causes blood stem cells to turn into disease-fighting ‘Natural Killer’ (NK) immune cells.

The discovery, by researchers at Imperial College London, UCL and the Medical Research Council’s National Institute for Medical Research, could one day help scientists boost the body’s production of [...]

Vitamin C can help protect DNA damage of skin cells

Washington, Sept 10 (ANI): Researchers at the University of Leicester and Institute for Molecular and Cellular Biology in Portugal have found that vitamin C can help protect DNA damage of skin cells and lead to better skin regeneration.

Previous research has shown that DNA repair is upregulated in people consuming vitamin C supplements.

In the new [...]

Kelly Osbourne blames her DNA for drug addiction

Washington, Sept 10 (ANI): ‘Dancing with the Stars’ contestant Kelly Osbourne has blamed her genes for her drug addiction.

Kelly’s father, rockstar Ozzy Osbourne, has had a long struggle with drugs, which makes her believe her DNA was pre-programmed to make her an addict.

Contactmusic quoted Kelly as telling BBC Radio 5 Live: “I don’t have any [...]

Engineered human fusion protein stops HIV-1 replication in mice

Washington, September 9 (ANI): Inspired by New World owl monkeys’ ability to make a fusion protein that potently blocks HIV-1 infection, scientists at the University of Geneva in Switzerland have engineered a human HIV-1 inhibitor.

Lead researcher Jeremy Luban points out that owl monkeys make AoT5Cyp, and that the human genome encodes the equivalent of [...]

New gene may provide better immune defense against anthrax

Washington, Sept 9 (ANI): Scientists from University of California have identified a gene in anthrax-causing bacteria that could be used as a potential therapeutic target for the deadly disease.

The ClpX gene in bacterium Bacillus anthracis not only contributes to the severity of the anthrax disease but also makes it more difficult for a patient’s immune [...]

Turning off oncogene may inhibit lung cancer stem cells’ growth

Washington, Sep 9 (ANI): A lung cancer oncogene, called PKCiota, is necessary for the proliferation of lung cancer stem cells, and turning it off could act as a key for the treatment of this deadly disease, according to scientists at the Mayo Clinic campus in Florida.

These stem cells are rare and powerful master cells that [...]

Fat-rich junk food may alter genes linked with type II diabetes

London, September 8 (ANI): A team of scientists in Sweden have warned that gorging too much on fat-rich junk food may cause drastic changes to a gene that helps muscle cells burn fat.

Juleen Zierath, of the Karolinska Institute in Stockholm, says that her team’s findings may help improve the scientific understanding of how type [...]

Missing protein in rare genetic brain disorder restored

Washington, Sep 7 (ANI): By using protease inhibitors, researchers at the University of California-San Francisco (UCSF) have restored to normal levels a key protein that is involved in early brain development, and causes the rare brain disorder lissencephaly.

Reduced levels of the protein called LIS1 have been shown to cause lissencephaly, which is characterized by brain [...]

Spare gene in fish provides raw materials for evolution of new Traits

Washington, September 4 (ANI): In a new research, scientists have discovered that a duplicate copy of a gene involved in embryonic development of fish has taken up a newer role in the evolution of fish scales.

Scientists have suspected that spare parts [...]

‘Master switch’ gene may help control obesity

Washington, Sept 4 (ANI): Scientists from University of Michigan claim to have discovered a gene, which when switched off, can control obesity in mice and help them remain thin.

According to Alan Saltiel, the Mary Sue Coleman Director of the U-M Life Sciences Institute, deleting the [...]

Single gene behind essential tremor, Parkinson’s disease identified

Washington, September 2 (ANI): A single gene promotes development of essential tremor in some patients and Parkinson’s disease in others has been identified by an international team of researchers.

In a study report published in Parkinsonism and Related Disorders, Mayo Clinic researchers in Florida and their collaborators worldwide note that patients with essential tremor shake [...]

Smoking, overweighing up breast cancer risk

Washington, September 2 (ANI): A study conducted in Canada has reinforced the correlation between being overweight, smoking and breast cancer.

Published in the Journal of Cancer Epidemiology, the study is unique because it did not include subjects who were diagnosed for BRCA1 and BRCA2 gene mutations, which predispose women to breast cancer.

The study entirely focused on [...]

Gene behind gum disease, osteoporosis, arthritis identified

Washington, Aug 31 (ANI): An international team of researchers have identified a gene that is common in the development of gum disease, rheumatoid arthritis, and osteoporosis.

Experts at Hospital for Special Surgery say that their findings about the gene, called interferon regulator factor-8 (IRF-8), may lead to new treatments in [...]

Counting duplicated genome segments now possible with new computational method

London, August 31 (ANI): Counting copies of duplicated genome sequences and doing initial analyses of their contents are possible with the aid of a new computational method, according to a study.

Led by scientists at the University of Washington (UW), the study suggests that the number of copies of particular DNA segments can differ from [...]

New, improved zebrafish cloning method may further human health research

London, August 31 (ANI): In what may eventually prove very useful in human health research, scientists at Michigan State University have come up with a more efficient method to clone zebra fish.

What makes this work an important achievement is the fact that zebra fish, which have served as an excellent model for understanding normal [...]

How plant tissues know which end is their growing tip

Washington, August 30 (ANI): A team of scientists has silenced nine genes in a multicellular organism, which allowed them to discover molecular secrets of how certain plant tissues know which end is their growing tip, also referred to as polarized growth.

The research was carried out by biologist Magdalena Bezanilla and colleagues at the University of [...]

Novel method to make safer human stem cells uses just one gene

London, Aug 29 (ANI): Inching closer to curing diseases like Parkinson’s using cells generated from a patient’s own body, researchers have successfully reprogrammed human nerve cells back to an embryo-like state by using just a single gene.

It is known that embryonic stem cells are pluripotent – they can develop into any of the body’s cell [...]