Washington, July 15 (ANI): Researchers at New Jersey’s only NCI-designated Comprehensive Cancer Center have taken a step towards unlocking the mysteries of why some women develop breast cancer at an earlier age than others.
The researchers have expanded a study to identify genetic markers in women with the disease, and their trial will now include more healthy volunteers as well.
According to state health statistics, roughly 13 percent of women diagnosed with breast cancer in New Jersey are younger than age 45, while nearly half of the women diagnosed with the disease and seen at CINJ are not yet 50.
And now, the investigators are hoping to shed light on these figures through an ongoing clinical trial whose goal is to identify genetic markers for the disease.
By including larger numbers of healthy women in the study, the researchers could pinpoint genetic differences between women who develop breast cancer and those who don’t.
Researchers led CINJ medical oncologist Dr. Kim M. Hirshfield recently discovered that some genes might be associated with increased risk of developing breast cancer, while others may actually protect against the development of the disease.
These same gene variations may also play a role in breast cancer outcomes.
“If we are able to identify these slight variations, we can learn more about how breast cancer develops and its outcomes. This information could one day lead to more tailored treatment for those with the disease and perhaps even better prevention methods and screening recommendations,” said Hirshfield.
She noted that the majority of women diagnosed with breast cancer have no known risk factors, and that only five to ten percent of breast cancers are actually caused by changes or mutations in known breast cancer genes.
Study participants will have blood drawn for laboratory analysis. The sample will be used to obtain blood cells as well as DNA. Facts about one’s breast health and overall medical history will be documented.
Both the blood sample and the clinical information will be analyzed and saved for possible future use.
Investigators are looking for more than 3,000 participants to complete the study.
Women and men aged 18 or older with no history of breast cancer, with a diagnosis of breast cancer, or a breast abnormality indicating increased risk for development of breast cancer are eligible to take part in the trial, although other criteria must be met. (ANI)

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Annie Lennox: I””m not anti-Israeli
Jerusalem, Jan 9 (ANI): Scottish singer-songwriter Annie Lennox has posted a message on her Facebook site, claiming that “she is not an anti-Israeli”.
The Eurythmics star participated in an anti-Israeli rally in London on January 3 slamming Israel””s actions in the Gaza Strip.
Responding to those calling her stand as betrayal, Lennox posted a comment entitled “Annie””s Second Official Statement regarding the Situation in Gaza.”
“I am not anti-Israeli nor have I ever been, and for anyone to say that I am is profoundly offensive and completely wrong,” The Jerusalem Post quoted her as saying in the post.
She wrote: “The reason why I spoke out when I did was because at that point in time there was a tiny window of opportunity to prevent a blood bath on both sides before the ground troops went in. I have never condoned suicide bombings, or the firing of missiles into Israel. I repeat… The slaughter of innocent lives on both sides is abhorrent.”
Her comment came in the wake of a number of angry postings on her Facebook site, one of which said that she picked a fine way to make a “fading career relevant.”
Lennox””s first greatest hits compilation, The Annie Lennox Collection, is scheduled to be released in March.
Another posting on Lennox””s facebook site read: “Where were you all this time as Israel has been bombarded by missiles over and over again. A continuous rain of attacks, we have lived in a constant state of alert, living in fear.
“We waited and waited and did nothing and now when we finally – finally – take a stand to defend ourselves are we treated like a terrorist nation. Unfortunately you were clearly oblivious to these events all this time. You have proven your ignorance and are standing on your soapbox without your facts.” (ANI)