Ricerca Releases Foresight Similarity Analysis Service

CONCORD, Ohio–(Business Wire)–
Ricerca Biosciences, LLC, a uniquely integrated preclinical contract research
organization (CRO) providing services to the biopharmaceutical industry, is
pleased to announce its innovative similarity analysis service, Foresight.

Foresight allows compound assay results to be compared against the assay results
of a large reference set of pharmacologically active compounds. The tool helps
predict in vivo effects from in vitro pharmacology data and provides insight
into additional, non-obvious compound activities.

The analysis service allows scientists to discover clues to the possibilities of
a compound, providing a resource for discovery and innovation. Foresight can be
used to direct compound modification to avoid adverse effects and determine new
indications for safe or novel compounds.

“Foresight provides a glimpse into the future of a compound and uses data from
the past to suggest ways to increase the acuity of that vision. Additionally,
Foresight allows our clients to apply their scientific know-how to years of
historical data with sophisticated analysis tools. Until August 31, 2010, we are
offering an introductory price of $3,500 per compound,” stated Chairman and CEO
of Ricerca, Ian Lennox.

For over forty years, Ricerca has been working with clients to profile compounds
in the discovery space. With the development of this tool, Ricerca can now offer
interpretation and predictive analysis of pharmacological data.

Ricerca offers a unique spectrum of services for the areas of preclinical
discovery and development for biopharmaceutical registration, agrochemical
registration and environmental analysis.

About Ricerca Biosciences

Ricerca Biosciences, LLC, offers a comprehensive suite of discovery and
preclinical services to support drug candidates from discovery through IND on a
global scale. Capabilities in discovery include molecular through in vivo
screening and profiling, medicinal chemistry, IND-enabling toxicology, API
process chemistry and cGMP manufacturing and scale-up. At Ricerca, our
scientific excellence and reliable, cost-effective strategies help accelerate
your drug discovery programs via our U.S. based facilities in Concord, Ohio, and
Bothell, Washington, and our ISO 9001-certified facilities in Taipei, Taiwan,
and Lyon, France. The Lyon and Bothell facilities also hold AAALAC
certification.

SCORR Marketing
Kelly Sladek, 308-237-5567
kelly@scorrmarketing.com

Copyright Business Wire 2010

Clavis Pharma ASA: Clavis Pharma announces the appointment of Athos Gianella-Borradori, MD

Oslo, Norway, June 24, 2010

Clavis Pharma ASA (OSE: CLAVIS) announces the appointment of Athos Gianella-Borradori MD
as Chief Medical Officer (CMO). Dr Gianella-Borradori is an experienced
onco-hematologist and drug developer, with 30 years experience in the field. He spent
the past 20 years in industry, focused on translational research and on the clinical
development of novel anti-cancer agents. During this career, he has held managerial and
senior clinical research and development roles at Novartis (Switzerland), Crucell (The
Netherlands), Bavarian Nordic (Germany), Cyclacel (United Kingdom) and, for the last
five years, at Serono, later at Merck Serono (Switzerland).

Before joining the industry, Dr Gianella-Borradori received his medical degree from the
University of Bern (Switzerland). He is board certified in Pediatric Hematology and
Oncology and practised for several years at European and US universities.

Dr Gianella-Borradori’s primary role at Clavis will be to drive the clinical development
of, elacytarabine, which is in a Phase III trial for patients with acute myeloid
leukaemia (AML), and of CP-4126 in partnership with Clovis Oncology, which is in Phase
II for patients with pancreatic cancer. He will also contribute to shape the strategy of
Clavis and will play a major role in the future developments of Clavis’ novel cancer
drug candidates.

Olav Hellebø, CEO, said: “We are very pleased that Athos will be joining the Clavis team
as CMO. We believe his extensive international experience in cancer drug development and
clinical experience in oncology and haematology will prove extremely valuable as we
progress our existing clinical programmes and expand our exciting pipeline of novel
LVT-derived cancer candidates. We believe the improved clinical characteristics of these
new drug candidates offer the potential to make a significant difference to the
treatment of patients with a range a cancer types.”

For further information contact:
Olav Hellebø
Chief Executive Officer
+47 24 11 09 50
olav.hellebo@clavispharma.com mailto:olav.hellebo@clavispharma.com

Gunnar Manum
Chief Financial Officer
+47 24 11 09 71
+47 95 17 91 90 (mob)
gunnar.manum@clavispharma.com mailto:gunnar.manum@clavispharma.com

Mark Swallow / Nina Enegren / David Dible
Citigate Dewe Rogerson
+44 207 282 2948
clavispharma@citigatedr.co.uk mailto:mark.swallow@citigatedr.co.uk

About Clavis Pharma
Clavis Pharma ASA is a clinical stage oncology drug development company based in Oslo,
Norway with a portfolio of novel anti-cancer drugs in development. These patented New
Chemical Entities (NCEs) are novel, improved versions of commercially successful drugs,
made using Clavis Pharma’s Lipid Vector Technology (LVT) chemistry. Data generated
suggests these potential breakthrough products may offer improved efficacy and reduced
side effects through enhanced pharmacokinetic properties, greater tissue penetration,
altered metabolism and, in certain cases, additional modes of action.

Clavis Pharma’s has several drug candidates in formal development studies:

*

Elacytarabine, an improved form of Ara-C, a leukaemia drug – about to commence a Phase
III randomized, controlled registration study in late-stage acute myeloid leukaemia;

*

Intravenous CP-4126, an improved version of gemcitabine – currently in a Phase II
comparative study with gemcitabine for the treatment of pancreatic cancer;

*

CP-4200, an azacitidine derivative – in preclinical development for myelodysplastic
syndrome (MDS), often a precursor to myeloma or leukaemia.

Clavis Pharma intends to commercialise its products through strategic alliances and
partnerships with experienced oncology businesses and, where and when commercially
appropriate, by establishing its own sales and marketing capabilities. CP-4126 is
licensed to Clovis Oncology in the Americas and Europe. Clavis Pharma has retained
rights in other territories and an option to co-promote CP-4126 in Europe.

The shares of Clavis Pharma ASA are listed on the Oslo Stock Exchange (ticker: CLAVIS).

Disclaimer
This news release contains forward-looking statements and forecasts based on
uncertainty, since they relate to events and depend on circumstances that will occur in
the future and which, by their nature, will have an impact on results of operations and
the financial condition of Clavis Pharma. There are a number of factors that could cause
actual results and developments to differ materially from those expressed or implied by
these forward-looking statements. Theses factors include, among other things, risks
associated with technological development, the risk that research & development will not
yield new products that achieve commercial success, the impact of competition, the
ability to close viable and profitable business deals, the risk of non-approval of
patents not yet granted and difficulties of obtaining relevant governmental approvals
for new products.

No expressed or implied representations or warranties are given concerning Clavis Pharma
or the accuracy or completeness of the information provided herein, and no claims shall
be made by the recipient hereof by virtue of this News Announcement or the information
contained herein.

Clavis Pharma(TM) is a registered trademark of Clavis Pharma ASA.

This information is subject of the disclosure requirements acc. to §5-12 vphl (Norwegian
Securities Trading Act)

This information is subject of the disclosure requirements acc. to §5-12 vphl (Norwegian
Securities Trading Act)

EpiCept Corporation Added to Preliminary List of Companies in Russell Microcap Index

TARRYTOWN, N.Y.–(Business Wire)–
Regulatory News:

EpiCept Corporation (Nasdaq and OMX Nordic Exchange: EPCT) announced today that
the Company`s common stock has been included on a list of preliminary additions
to the Russell Microcap Index posted by Russell Investments on June 11, 2010 on
www.russell.com. These changes are expected to go into effect after the close of
trading on Friday, June 25, 2010.

“Inclusion in this index would represent an important step in EpiCept`s
evolution, as the equity markets recognize and reflect our growth into a
commercial enterprise,” said Jack Talley, EpiCept`s president and chief
executive officer. “We are pleased that EpiCept stock can benefit from the wider
exposure offered by its preliminary addition to the index,” he added.

The Russell Microcap Index measures the performance of the microcap segment of
the U.S. equity market and is comprised of the smallest 1,000 companies in the
Russell 3000 Index, plus the next smallest 1,000 companies. The Russell indexes
are widely used by investment managers and institutional investors for index
funds and as benchmarks for passive and active investment strategies. The
indexes are reconstituted annually.

About EpiCept Corporation

EpiCept is focused on the development and commercialization of pharmaceutical
products for the treatment of cancer and pain. The Company’s lead product is
Ceplene®, which has been granted full marketing authorization by the European
Commission for the remission maintenance and prevention of relapse in adult
patients with Acute Myeloid Leukemia (AML) in first remission. The Company has
two oncology drug candidates currently in clinical development that were
discovered using in-house technology and have been shown to act as vascular
disruption agents in a variety of solid tumors. The Company’s pain portfolio
includes EpiCept NP-1, a prescription topical analgesic cream in late-stage
clinical development designed to provide effective long-term relief of pain
associated with peripheral neuropathies.

Forward-Looking Statements

This news release and any oral statements made with respect to the information
contained in this news release contain forward-looking statements within the
meaning of the Private Securities Litigation Reform Act of 1995. Such
forward-looking statements include statements which express plans, anticipation,
intent, contingency, goals, targets, future development and are otherwise not
statements of historical fact. These statements are based on our current
expectations and are subject to risks and uncertainties that could cause actual
results or developments to be materially different from historical results or
from any future results expressed or implied by such forward-looking statements.
Factors that may cause actual results or developments to differ materially
include: the risk that Ceplene will not receive regulatory approval or marketing
authorization in the United States or Canada, the risk that Ceplene will not
achieve significant commercial success, the risk that any required post-approval
clinical study for Ceplene will not be successful, the risk that we will not be
able to maintain our final regulatory approval or marketing authorization for
Ceplene, the risks associated with the adequacy of our existing cash resources
and our ability to continue as a going concern, the risks associated with our
ability to continue to meet our obligations under our existing debt agreements,
the risk that Azixa will not receive regulatory approval or achieve significant
commercial success, the risk that we will not receive any significant payments
under our agreement with Myriad, the risk that the development of our other
apoptosis product candidates will not be successful, the risk that clinical
trials for EpiCept NP-1 or crolibulinTM will not be successful, the risk that
EpiCept NP-1 or crolibulin will not receive regulatory approval or achieve
significant commercial success, the risk that we will not be able to find a
partner to help conduct the Phase III trials for EpiCept NP-1 on attractive
terms, a timely basis or at all, the risk that our other product candidates that
appeared promising in early research and clinical trials do not demonstrate
safety and/or efficacy in larger-scale or later stage clinical trials, the risk
that we will not obtain approval to market any of our product candidates, the
risks associated with dependence upon key personnel, the risks associated with
reliance on collaborative partners and others for further clinical trials,
development, manufacturing and commercialization of our product candidates; the
cost, delays and uncertainties associated with our scientific research, product
development, clinical trials and regulatory approval process; our history of
operating losses since our inception; the highly competitive nature of our
business; risks associated with litigation; and risks associated with our
ability to protect our intellectual property. These factors and other material
risks are more fully discussed in our periodic reports, including our reports on
Forms 8-K, 10-Q and 10-K and other filings with the U.S. Securities and Exchange
Commission. You are urged to carefully review and consider the disclosures found
in our filings which are available at www.sec.gov or at www.epicept.com. You are
cautioned not to place undue reliance on any forward-looking statements, any of
which could turn out to be wrong due to inaccurate assumptions, unknown risks or
uncertainties or other risk factors.

###

EPCT-GEN

*Azixa is a registered trademark of Myriad Genetics, Inc.

EpiCept Corporation
Robert W. Cook, 914-606-3500
rcook@epicept.com
or
Media:
Feinstein Kean Healthcare
Greg Kelley, 617-577-8110
gregory.kelley@fkhealth.com
or
Investors:
Lippert/Heilshorn & Associates
Kim Sutton Golodetz, 212-838-3777
kgolodetz@lhai.com
or
Bruce Voss, 310-691-7100
bvoss@lhai.com

Copyright Business Wire 2010

Pain Therapeutics to Present at Needham Healthcare Conference

SAN MATEO, Calif., June 4, 2010 (GLOBE NEWSWIRE) — Pain Therapeutics, Inc.
(Nasdaq:PTIE) today announced that management will present at the Needham
Healthcare Conference in New York City on Wednesday, June 9th at 4:00 p.m.
Eastern Time.

The presentation will be webcast live and may be accessed from the home page of
Pain Therapeutics’ website at www.paintrials.com. A replay of the webcast will
continue to be available on the website for up to 90 days.

About Pain Therapeutics, Inc.

Pain Therapeutics, Inc. is a biopharmaceutical company that develops novel
drugs. In addition to REMOXY(R), a unique abuse-resistant controlled-release
oxycodone, the company has three drug candidates in clinical programs, including
a novel radio-labeled monoclonal antibody to treat metastatic melanoma, as well
as PTI-202 and PTI-721. Pain Therapeutics is also working on a new treatment for
patients with hemophilia.

CONTACT: Pain Therapeutics, Inc.
Judy Ishida, Administrative Manager
650-645-1924
IR@paintrials.com

CytRx to Present at the Jefferies 2010 Global Life Sciences Conference

LOS ANGELES–(Business Wire)–
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical company specializing in
oncology, today announced that David J. Haen, CytRx`s Vice President of Business
Development, will present at the Jefferies 2010 Global Life Sciences Conference
on Friday, June 11, 2010, at 12:45 p.m. Eastern time (9:45 a.m. Pacific time) in
New York City.

The CytRx presentation will include a discussion of the Company`s actions to
advance the clinical development of its high-value oncology development
pipeline, including a discussion of its recently initiated Phase 2 clinical
trial to evaluate the efficacy and safety of bafetinib in patients with
high-risk B-cell chronic lymphocytic leukemia, and plans to initiate up to five
additional Phase 2 oncology clinical trials in 2010. A live webcast of the
presentation will be available at www.cytrx.com and a webcast replay will be
archived on the Company`s Web site for 90 days.

About CytRx Corporation

CytRx Corporation is a biopharmaceutical research and development oncology
company engaged in the development of high-value human therapeutics. The CytRx
oncology pipeline includes three programs in clinical development for cancer
indications: INNO-206, bafetinib and tamibarotene. The Company recently
announced initiation of a Phase 2 clinical trial with bafetinib as a treatment
for high-risk B-cell chronic lymphocytic leukemia, and plans to initiate two
additional Phase 2 clinical trials in glioblastoma multiforme (a common and
aggressive type of primary brain tumor) and advanced prostate cancer. CytRx also
recently announced plans to initiate three Phase 2 clinical trials with its
oncology candidate INNO-206 as a treatment for pancreatic cancer, gastric cancer
and soft tissue sarcomas. In addition, CytRx is developing two drug candidates
based on its industry-leading molecular chaperone technology, which aims to
repair or degrade misfolded proteins associated with disease. CytRx also
maintains a 28% equity interest in publicly traded RXi Pharmaceuticals, Inc.
(NASDAQ:RXII). For more information on the Company, visit http://www.cytrx.com.

Legend Securities, Inc.
Thomas Wagner
800-385-5790 x152
718-233-2600 x152
twagner@legendsecuritiesinc.com

Copyright Business Wire 2010

Chelsea Therapeutics to Present at 9th Annual Needham Healthcare Conference

CHARLOTTE, N.C., June 3, 2010 (GLOBE NEWSWIRE) — Chelsea Therapeutics
International, Ltd. (Nasdaq:CHTP) is scheduled to present at the 9th Annual
Needham Healthcare Conference at 2:00 PM ET on Wednesday June 9, 2010 at the New
York Palace Hotel in New York City.

Dr. Simon Pedder, Chelsea’s president and chief executive officer, will provide
a brief overview of the company’s product pipeline, clinical development status
and upcoming milestones.

Dr. Pedder’s presentation will be webcast live and archived for 30 days on
Chelsea’s website, www.chelseatherapeutics.com.

About Chelsea Therapeutics

Chelsea Therapeutics is a biopharmaceutical development company that acquires
and develops innovative products for the treatment of a variety of human
diseases. Chelsea’s most advanced drug candidate, Northera(TM) (droxidopa), is
an orally active synthetic precursor of norepinephrine initially being developed
for the treatment of neurogenic orthostatic hypotension. In addition to
Northera, Chelsea is also developing a portfolio of metabolically inert oral
antifolate molecules engineered to have potent anti-inflammatory and anti-tumor
activity to treat a range of immunological disorders, including two clinical
stage product candidates: CH-1504 and CH-4051. Preclinical and clinical data
suggest superior safety and tolerability, as well as increased potency versus
methotrexate (MTX).

This press release contains forward-looking statements regarding future events.
These statements are just predictions and are subject to risks and uncertainties
that could cause the actual events or results to differ materially. These risks
and uncertainties include risks and costs of drug development, risk of
regulatory approvals, our reliance on our lead drug candidates droxidopa and
CH-4051, reliance on collaborations and licenses, intellectual property risks,
our need to raise additional operating capital in the future, our history of
losses, competition, market acceptance for our products if any are approved for
marketing, and reliance on key personnel including specifically Dr. Pedder.

CONTACT: Chelsea Therapeutics
Investor/Media Relations
Kathryn McNeil
718-788-2856

Pain Therapeutics to Present at Jefferies Healthcare Conference

SAN MATEO, Calif., June 3, 2010 (GLOBE NEWSWIRE) — Pain Therapeutics, Inc.
(Nasdaq:PTIE) today announced that management will present at the Jefferies
Global Life Sciences Conference in New York City on Tuesday, June 8th at 4:00
p.m. Eastern Time.

The presentation will be webcast live and may be accessed from the home page of
Pain Therapeutics’ website at www.paintrials.com. A replay of the webcast will
continue to be available on the website for up to 90 days.

About Pain Therapeutics, Inc.

Pain Therapeutics, Inc. is a biopharmaceutical company that develops novel
drugs. In addition to REMOXY(R), a unique abuse-resistant controlled-release
oxycodone, the company has three drug candidates in clinical programs, including
a novel radio-labeled monoclonal antibody to treat metastatic melanoma, as well
as PTI-202 and PTI-721. Pain Therapeutics is also working on a new treatment for
patients with hemophilia.

CONTACT: Pain Therapeutics, Inc.
Judy Ishida, Administrative Manager
650-645-1924
IR@paintrials.com

Aoxing Pharmaceutical Company and Phoenix PharmaLabs, Inc. Announce Strategic Alliance to Co-Develop a Novel Class of

NEW YORK, NY and SALT LAKE CITY, UT, Jun 03 (MARKET
WIRE) —
Aoxing Pharmaceutical Company, Inc. (NYSE Amex: AXN) (“Aoxing Pharma”)
and Phoenix PharmaLabs, Inc. (“PPL”) today jointly announced that the
companies have entered into a co-development, manufacturing and license
agreement related to a novel class of poly-receptor active opioid-like
drug candidates targeting pain and substance abuse and addiction
treatment.

Agreement Highlights

– Aoxing Pharma and PPL entered into a multi-party collaboration
agreement for the development and regulatory approval of a novel class
of therapeutics in both China and ex-China territories. The two
companies will continue to co-collaborate with the U.S. National
Institute of Drug Abuse (“NIDA”) and the Chinese National Institute on
Drug Dependence at Beijing University (“NIDD”).
– Aoxing Pharma received an exclusive license to develop a new class of
poly-receptor active opioid-like drug candidates being developed by
PPL for therapeutic indications in pain management and substance abuse
and addiction treatment in the Country of China, Macau and Hong Kong.
– PPL will receive tiered royalties based on Adjusted Gross Sales (AGS)
in the licensed territories, defined and agreed by both companies.
Aoxing Pharma receives tiered royalties based on Adjusted Gross Sales
(AGS) from the territories held by PPL, defined and agreed by both
companies.
– Aoxing Pharma will execute and fund the development, regulatory
applications, manufacturing and marketing of the licensed drug
candidates in China, while PPL will fund all development in all other
territories.

“We are pleased to announce this global strategic alliance, as one
of our primary goals is to introduce a novel class of therapeutics to
patients around the world with pain or drug addiction problems,” said Dr.
John A. Lawson, Chairman and Chief Executive Officer of Phoenix
PharmaLabs, Inc. “Our drug development program has been funded and
supported by the U.S. National Institute of Drug Abuse (‘NIDA’) for many
years. . We are planning on filing an IND in the U.S. for the first
product candidate early next year. Aoxing Pharma is an emerging leader in
the narcotics and neurological pharmaceutical business in China, which
ideally complements our existing offerings. We view Aoxing Pharma as an
ideal strategic partner given their solid presence and complementary
pipeline.”

“This partnership provides an exciting opportunity to bring in additional
unique product candidates to our growing pipeline for an important market
here in China, while also allowing us to capitalize on potential sales
outside of China,” said Zhenjiang Yue, Chairman and Chief Executive
Officer of Aoxing Pharma. “We believe that this class of new molecules
represents a strong growth opportunity to expand upon our existing
pipeline products in the areas of drug addiction treatment and pain
management, including the sublingual tablet of Buprenorphine/Naloxone,
which is currently under our clinical development and expected to be
launched in China over the next 24 months. With 1.3 million registered
drug addicts and limited pharmacological options available in China,
these new product opportunities have the potential to help serve this
unfortunately rapid growing market.”

About Poly-Receptor Active Opioid-Like Drugs:

Phoenix PharmaLabs’ poly-receptor opioid-like drugs may represent a new
“class” of opioid drugs, with unique pain receptor characteristics never
before seen. PPL believes there are no other opioid drugs with similar
receptor binding profiles. PPL drugs have a unique reduced Mu-receptor
and moderate Kappa receptor activity allowing them to be moderately
active at all three pain receptors. In pre-clinical testing, this
balanced partial activity appears to allow full pain relief potency while
eliminating or reducing such side effects as respiratory depression and
addiction. In short, PPL drugs appear to mimic the natural endorphins in
the healthy brain. For more information, please visit:

http://www.phoenixpharmalabs.com/

About Phoenix PharmaLabs Inc.

Phoenix PharmaLabs, Inc. is a privately held, clinical-stage Utah drug
discovery company focusing on the development and commercialization of
new non-addictive treatments for pain, and new therapies for the
treatment of opiate addiction. The company was founded in 2002 with the
mission to bring its new class of opioid pain therapies and addiction
treatment therapies to the Clinic. For more information, please visit:

http://www.phoenixpharmalabs.com/

About Aoxing Pharmaceutical Company, Inc.

Aoxing Pharmaceutical Company, Inc is a US incorporated specialty
pharmaceutical company with its main operations in China, specializing in
research, development, manufacturing and distribution of a variety of
narcotics and pain-management products. Headquartered in Shijiazhuang
City, outside Beijing, Aoxing has the largest and most advanced
manufacturing facility for highly regulated narcotic medicines. Its
facility is one of the few GMP facilities licensed for the manufacture of
narcotic medicines by the China State Food and Drug Administration
(SFDA). It has joint venture collaboration with Johnson Matthey Plc to
produce and market narcotics and neurological drugs in China. It also has
strategic alliance partnership with QRxPharma and American Oriental
Bioengineering, Inc. For more information, please visit:
www.aoxingpharma.com.

Safe Harbor Statement from Aoxing Pharmaceutical Company, Inc

Statements made in this press release are forward-looking and are made
pursuant to the safe harbor provisions of the Securities Litigation
Reform Act of 1995. Such statements involve risks and uncertainties that
may cause actual results to differ materially from those set forth in
these statements. The economic, competitive, governmental, technological
and other risk factors identified in the Company’s filings with the
Securities and Exchange Commission, including the Form 10-K for the year
ended June 30, 2009, may cause actual results or events to differ
materially from those described in the forward looking statements in this
press release. The Company undertakes no obligation to publicly update or
revise any forward-looking statements, whether because of new
information, future events, or otherwise.

Investor Relations Contact:
Timmy Chou
Vice President, CFO
Tel +1 801 420 0285
Email: tim@phoenixpharmalabs.com

Investor Relations Contact:
Brian Korb
Vice President
The Troup Group LLC
Tel: +1 646 378 2923
Email: bkorb@troutgroup.com

Copyright 2010, Market Wire, All rights reserved.

Synta Pharmaceuticals to Present at the Jefferies Global Life Sciences Conference

Company to Webcast Presentation on June 10
LEXINGTON, Mass.–(Business Wire)–
Synta Pharmaceuticals Corp. (NASDAQ: SNTA), a biopharmaceutical company focused
on discovering, developing, and commercializing small molecule drugs to treat
severe medical conditions, today announced that the Company will be presenting
at the Jefferies Global Life Sciences Conference on Thursday, June 10 at 3:30
p.m. (ET) in New York.

A live audio webcast and replay of the presentation will be available on the
“Investors” section of the Company’s website, www.syntapharma.com.

About Synta Pharmaceuticals

Synta Pharmaceuticals Corp. is a biopharmaceutical company focused on
discovering, developing, and commercializing small molecule drugs to extend and
enhance the lives of patients with severe medical conditions, including cancer
and chronic inflammatory diseases. Synta has a unique chemical compound library,
an integrated discovery engine, and a diverse pipeline of clinical- and
preclinical-stage drug candidates with distinct mechanisms of action and novel
chemical structures. All Synta drug candidates were invented by Synta scientists
using our compound library and discovery capabilities. For more information,
please visit www.syntapharma.com.

Synta Pharmaceuticals Corp.
Rob Kloppenburg, 781-541-7125

Copyright Business Wire 2010

PolyMedix to Present at the Noble Financial Equity Conference

RADNOR, Pa.–(Business Wire)–
PolyMedix, Inc. (OTC BB: PYMX), an emerging biotechnology company focused on
developing new therapeutic drugs to treat acute cardiovascular disorders and
infectious diseases, will be presenting at the Noble Financial Sixth Annual
Equity Conference. The Conference will take place June 7-8, 2010 at the Hard
Rock Hotel in Hollywood, Florida.

Edward Smith, Vice President of Finance & CFO of PolyMedix will present on
Tuesday, June 8, 2010 at 1:30 PM ET. The presentation will be webcast live and
may be accessed on the Company`s website at www.polymedix.com. A replay will be
available for 90 days following the event.

About PolyMedix, Inc.

PolyMedix is a publicly traded biotechnology company focused on the development
of novel drugs and biomaterials for the treatment of serious acute
cardiovascular disorders and infectious diseases. PolyMedix uses a rational drug
design approach to create non-peptide small molecule drug candidates and
polymers that mimic the activity of proteins. PMX-60056, PolyMedix`s lead
heptagonist compound, is being developed to reverse the anticoagulant activity
of both heparin and low molecular weight heparins. PolyMedix believes that
PMX-60056 could potentially be a safer and easier to use anticoagulant reversing
agent, with broader activity, than the currently approved therapy. PMX-30063,
PolyMedix`s lead antibiotic compound, is a small molecule that mimics human
host-defense proteins and has a completely different mechanism of action
distinct from those of current antibiotic drugs, a mechanism which is intended
to make bacterial resistance unlikely to develop. PolyMedix plans to develop
this compound for serious systemic Staphylococcal infections, including MRSA.
Both PMX-60056 heptagonist and PMX-30063 antibiotic are currently undergoing
clinical testing. PolyMedix also plans to continue the development of its
PolyCides, polymeric formulations as antimicrobial biomaterials, which can be
used as additives to paints, plastics, and textiles to create self-sterilizing
products and surfaces. For more information, please visit our website at
www.polymedix.com.

This press release contains forward-looking statements made pursuant to the safe
harbor provisions of the Private Securities Litigation Reform Act of 1995 that
involve risks, uncertainties and assumptions that could cause PolyMedix`s actual
results and experience to differ materially from anticipated results and
expectations expressed in these forward looking statements. PolyMedix has in
some cases identified forward-looking statements by using words such as
“anticipates,” “believes,” “hopes,” “estimates,” “looks,” “expects,” “plans,”
“intends,” “goal,” “potential,” “may,” “suggest,” and similar expressions. Among
other factors that could cause actual results to differ materially from those
expressed in forward-looking statements, PolyMedix`s compounds may not enter or
successfully complete clinical testing, or be granted regulatory approval to be
sold and marketed in the United States or elsewhere. A more complete description
of these risk factors is included in PolyMedix`s filings with the Securities and
Exchange Commission. You should not place undue reliance on any forward-looking
statements. PolyMedix undertakes no obligation to release publicly the results
of any revisions to any such forward-looking statements that may be made to
reflect events or circumstances after the date of this press release or to
reflect the occurrence of unanticipated events, except as required by applicable
law or regulation.

PolyMedix, Inc.
Company:
Lisa Caperelli, 484-598-2406
Director, Investor Relations & Corporate Communications
lcaperelli@polymedix.com
or
Investors:
Erika Moran
emoran@investorrelationsgroup.com
or
Media:
Janet Vasquez, 212-825-3210
jvasquez@investorrelationsgroup.com

Ablexis Secures $12 Million in Series A Funding to Engineer and Commercialize Next-Generation Platforms for Antibody Drug Discovery

Round Includes Third Rock Ventures and Pfizer Venture Investments
SAN FRANCISCO–(Business Wire)–
Ablexis, LLC, a biotechnology company dedicated to developing an innovative,
next-generation platform for antibody drug discovery, announced today that it
has completed a $12 million Series A financing. The round was led by Third Rock
Ventures and included Pfizer Venture Investments. Proceeds from the financing
will be used to continue advancing Ablexis` proprietary AlivaMab Mouse
transgenic mouse platform for the discovery of human therapeutic antibodies.

“There are significant unmet commercial needs for a transgenic mouse platform
for therapeutic antibody discovery,” said Larry Green, Ph.D., chief executive
officer of Ablexis. “In addition, advances in the understanding of immune
responses, antibody drug discovery and development, and genetic engineering
methods all provided a basis for innovating and improving upon existing platform
technologies. Ablexis is leveraging these advances and the significant
experience of our team for the creation of the AlivaMab Mouse, an efficient,
innovative, next-generation transgenic mouse platform for antibody drug
discovery. Ablexis will commercialize this valuable platform through creative
partnering strategies.”

Over ten years of fully human antibody drug discovery have demonstrated that
transgenic mouse platforms are the most productive platform for successful
antibody drug discovery and development. These platforms harness the power of
the in vivo immune system to yield very high affinity antibody drug candidates
with desirable characteristics of potency, specificity, solubility and reduced
chances of immunogenicity. Combined with their broad target applicability,
transgenic mice bring an unparalleled efficiency and probability of success to
the discovery and development of quality drug candidates. Recent, major changes
in the landscape of providers in this space, including the acquisition of
Abgenix`s XenoMouse® technology by Amgen and Medarex`s HuMAb-Mouse® technology
by Bristol-Myers Squibb, have dramatically diminished access to transgenic mouse
platforms for therapeutic antibody discovery.

“In our conversations with pharma and biotech companies, Third Rock repeatedly
heard about the need for a new, robust transgenic mouse antibody platform,” said
Cary Pfeffer, M.D., partner at Third Rock Ventures and member of Ablexis` board
of directors. “Ablexis` solution, based on Dr. Green`s profound understanding of
the strengths and limitations of earlier generation technologies represents an
important step forward and promises to enhance the life-changing advancements
being made through today`s antibody discovery and development efforts.”

Barbara Dalton, vice president of venture capital at Pfizer commented, “We
expect that Ablexis` innovative transgenic mouse platform will fulfill a
strategic need for many companies like Pfizer as a platform to develop high
quality antibody drug candidates. This investment supports an interesting
business model for the development of important technology platforms for our
industry.”

Dr. Green leads Ablexis as chief executive officer and brings 18 years of
leadership in antibody discovery, therapeutic product development and
collaborative research experience to the Ablexis team. Dr. Green was a founder
of Abgenix, where he served in several executive level research positions and
led or contributed to more than 50 antibody discovery projects. Dr. Green is
joined by Hiroaki Shizuya, M.D., Ph.D., who serves as Ablexis`s resident advisor
in molecular biology. As the creator of bacterial artificial chromosome
technology, Dr. Shizuya contributes unique insights into molecular biology, DNA
manipulation and genome characterization.

Joining Dr. Green and Dr. Pfeffer on Ablexis`s board of directors is Lou
Tartaglia, Ph.D., partner at Third Rock Ventures. Jake Bauer, senior associate
at Third Rock Ventures, Jennifer Friel Goldstein, director at Pfizer Venture
Investments, and Alex Suh, managing director at California Technology Ventures,
are board observers.

About Ablexis, LLC

Ablexis, LLC was founded in December 2009 and is based on technology established
by Aliva Biopharmaceuticals, Inc., which was founded in 2001 by Hiroaki Shizuya,
M.D., Ph.D., a pioneer of bacterial artificial chromosome technology. Ablexis is
creating the AlivaMab Mouse, an innovative, next-generation transgenic mouse
platform that will provide the foundation for the efficient discovery and
development of the next wave of human therapeutic antibodies. Ablexis has filed
patent applications covering its core technologies, compositions and utilities
for its AlivaMab mice. The company is based in San Francisco, California and
more information can be found by visiting the company`s website at
www.ablexis.com.

About Third Rock Ventures

Third Rock Ventures is a premier venture firm focused on life sciences,
investing and launching companies that make a difference in people`s lives.
Collaborating with entrepreneurs, the Third Rock team applies its deep expertise
to establish the roadmap and building blocks for a rapidly growing and highly
successful life sciences company. The Third Rock team has a unique vision and
experience in building great companies, extensive life science industry and
academic networks and a collective track record for creatively managing the
value creation path to deliver exceptional performance. For more information,
please visit www.thirdrockventures.com.

About Pfizer Venture Investments

Pfizer Venture Investments (PVI), the venture capital arm of Pfizer Inc., was
founded in 2004 and invests for return in areas of current or future strategic
interest to Pfizer. PVI seeks to remain at the forefront of life science
advances, looking to identify and invest in emerging companies that are
developing compounds and technologies that have the potential to enhance
Pfizer’s pipeline and shape the future of the pharmaceutical industry. With a
strong focus on growth stage opportunities, PVI invests in a broad array of
healthcare related areas, including therapeutics, platform technologies,
diagnostics, drug delivery, pharmaceutical services, healthcare IT, and other
technologies impacting drug discovery and development. For more information,
please visit www.pfizer.com/research/licensing/venture_investments.jsp.

Pure Communications, Inc.
Sheryl Seapy, 949-608-0841

Copyright Business Wire 2010

New test can help assess efficacy of Alzheimer’s drugs

Washington, Apr 10 (ANI): Researchers at Washington University School of Medicine in St. Louis have developed a new test that can assess whether an Alzheimer’s drug could really reduce the production of amyloid beta (A-beta)- one of the possible underlying causes of Alzheimer’s disease in humans.

With the test, called stable isotope-linked kinetics (SILK), the researchers showed that an Alzheimer’s drug given to healthy volunteers reduced A-beta production

The test could speed up the development of new treatments for the disease.

In the clinical trials by Eli Lilly and Company, the scientists are studying the drug candidate, LY450139, which is also known as semagacestat.

Ongoing clinical trials are studying the effect that semagacestat may have on cognitive function and biochemical and brain imaging biomarkers in patients with Alzheimer’s disease.

The researchers said that they wanted to see if SILK could detect the drug’s impact on A-beta synthesis in healthy volunteers.

“Bringing an Alzheimer’s disease drug into clinical trials from tests in animal models has always been challenging. We haven’t had a way to quickly and accurately assess a drug’s effects, and that meant there always had to be some degree of educated guesswork when it came to setting the optimal dosage for humans. SILK may help to eliminate much of that guesswork,” said study director Randall Bateman.

The researchers are currently using SILK to know if increased A-beta production, reduced clearance or a combination of the two lead to the A-beta buildup in the brain- a process believed to trigger Alzheimer’s disease.

Until SILK, there has not been a way to directly measure the production or clearance of A-beta.

Scientists have assessed the efficacy of potential new Alzheimer’s drug candidates by monitoring the cognitive functions of patients with the disease for extended periods of time, which require large, lengthy and expensive studies.

In the new study, the scientists reported a dose-dependent drop in A-beta production, and measured an 84 percent reduction in A-beta production with the highest study drug dose.

The SILK procedure takes 36 hours, but provides scientists a more detailed assessment of amyloid beta production and clearance levels than they can obtain through conventional methods.

“You could use a spinal tap to look directly at the amount of A-beta present in the cerebrospinal fluid, but we’ve shown that natural processes cause A-beta levels to change dynamically. Such changes make it more difficult to assess the effects of a drug in that fashion,” said Bateman.

The results have been published in Annals of Neurology. (ANI)