Russia calls for crackdown on Afghan drugs

(Reuters) – Russia on Wednesday rolled out a global initiative to stem Afghan drug trafficking to include a comprehensive crackdown on opium poppy growing, but the United States gave a cool reception to the plan.

World | Russia

Russia, the world’s largest per capita heroin consumer with an estimated 30,000 people dying of abuse annually, has tried to take the lead to combat a flow of drugs from Afghanistan.

Moscow believes U.S.-led NATO forces fighting the Taliban in Afghanistan are reluctant to uproot local drug output, which has surged after their invasion in 2001 and now accounts for 90 percent of all heroin produced globally.

The U.S. said eradicating poppy plantations would push disgruntled Afghan farmers into the hands of insurgents.

Russian President Dmitry Medvedev said the world community must work out a joint approach to combat Afghan drugs.

“We see drug addiction as a significant, the most severe threat to the development of our country, to the health of our people,” Medvedev told a forum on Afghan drug production.

Russian Foreign Minister Sergei Lavrov called for a binding United Nations resolution on Afghan drugs.

“We are confident there is a need for the U.N. Security Council to call the Afghan drug threat as a threat to international peace and security,” he said.

Russia’s anti-drugs czar, Viktor Ivanov, said the adoption of such a resolution by the U.N. would create a legal basis for an international fight against Afghan drugs.

The plan drafted by Moscow envisages eradication of no less than 25 percent all those areas growing opium poppies, from which heroin is derived, up from last year’s 3 percent.

Moscow also wants the destruction of poppy fields to form part of the remit of NATO forces operating in Afghanistan.

“We should act at least as decisively fighting drug production in Afghanistan as it is done when fighting cocaine production in South America,” Lavrov said, referring to the effort the U.S. puts into combating the cocaine trade.

Injecting Afghan heroin with unclean needles is blamed by the Russian country for its AIDS epidemic.

Experts say around one million people in Russia are infected with the HIV virus, and that the number of cases has doubled over the past eight years mainly driven by drug users, who account for up to 80 percent of the cases.

U.S. COOL TO PLAN, NATO TRANSIT TO CONTINUE

Patrick Ward, acting deputy director for supply reduction at the White House Office of National Drug Control Policy, warned the forum of the dangers of pushing poor peasant farmers into the hands of the militants.

“This will further undermine the rule of law and reinforce the nexus between drugs and terrorism,” he said.

In March NATO rejected Russian calls for it to eradicate opium poppy fields in Afghanistan, saying it cannot be in a situation where it removes “the only source of income of people who live in the second poorest country of the world.”

The Russia plan envisages job creation schemes.

NATO and Afghan forces conducted 56 anti-drug operations in the first three months of 2010, which led to the destruction of 16.3 metric tons of opium, Ward said.

Seventy metric tons of heroin worth $13 billion is consumed in Russia every year, according to U.N. estimates.

Any rift between Moscow and Washington over the drugs issue would not affect the transits of cargo for NATO troops in Afghanistan via Russia, Moscow’s envoy to NATO Dmitry Rogozin said on the sidelines of the forum.

“We’re interested in the transit ourselves, so that the coalition acts without disruptions,” he said. “We’re not going to shoot ourselves in the foot merely to spite them.”

(Reporting by Alexei Anishchuk; Editing by Ralph Boulton)

Russia calls for crackdown on Afghan drugs, U.S. tepid

MOSCOW, June 9 (Reuters) – Russia on Wednesday rolled out a global initiative to stem Afghan drug trafficking to include a comprehensive crackdown on opium poppy growing, but the United States gave a cool reception to the plan.

Russia, the world’s largest per capita heroin consumer with an estimated 30,000 people dying of abuse annually, has tried to take the lead to combat a flow of drugs from Afghanistan.

Moscow believes U.S.-led NATO forces fighting the Taliban in Afghanistan are reluctant to uproot local drug output, which has surged after their invasion in 2001 and now accounts for 90 percent of all heroin produced globally.

The U.S. said eradicating poppy plantations would push disgruntled Afghan farmers into the hands of insurgents.

Russian President Dmitry Medvedev said the world community must work out a joint approach to combat Afghan drugs.

“We see drug addiction as a significant, the most severe threat to the development of our country, to the health of our people,” Medvedev told a forum on Afghan drug production.

Russian Foreign Minister Sergei Lavrov called for a binding United Nations resolution on Afghan drugs.

“We are confident there is a need for the U.N. Security Council to call the Afghan drug threat as a threat to international peace and security,” he said.

Russia’s anti-drugs czar, Viktor Ivanov, said the adoption of such a resolution by the U.N. would create a legal basis for an international fight against Afghan drugs.

The plan drafted by Moscow envisages eradication of no less than 25 percent all those areas growing opium poppies, from which heroin is derived, up from last year’s 3 percent.

Moscow also wants the destruction of poppy fields to form part of the remit of NATO forces operating in Afghanistan.

“We should act at least as decisively fighting drug production in Afghanistan as it is done when fighting cocaine production in South America,” Lavrov said, referring to the effort the U.S. puts into combating the cocaine trade.

Injecting Afghan heroin with unclean needles is blamed by the Russian country for its AIDS epidemic.

Experts say around one million people in Russia are infected with the HIV virus, and that the number of cases has doubled over the past eight years mainly driven by drug users, who account for up to 80 percent of the cases.

U.S. COOL TO PLAN, NATO TRANSIT TO CONTINUE

Patrick Ward, acting deputy director for supply reduction at the White House Office of National Drug Control Policy, warned the forum of the dangers of pushing poor peasant farmers into the hands of the militants.

“This will further undermine the rule of law and reinforce the nexus between drugs and terrorism,” he said.

In March NATO rejected Russian calls for it to eradicate opium poppy fields in Afghanistan, saying it cannot be in a situation where it removes “the only source of income of people who live in the second poorest country of the world”.

The Russia plan envisages job creation schemes.

NATO and Afghan forces conducted 56 anti-drug operations in the first three months of 2010, which led to the destruction of 16.3 metric tons of opium, Ward said.

Seventy metric tons of heroin worth $13 billion is consumed in Russia every year, according to U.N. estimates.

Any rift between Moscow and Washington over the drugs issue would not affect the transits of cargo for NATO troops in Afghanistan via Russia, Moscow’s envoy to NATO Dmitry Rogozin said on the sidelines of the forum.

“We’re interested in the transit ourselves, so that the coalition acts without disruptions,” he said. “We’re not going to shoot ourselves in the foot merely to spite them.” (Reporting by Alexei Anishchuk; Editing by Ralph Boulton)

Aoxing Pharmaceutical Company and Phoenix PharmaLabs, Inc. Announce Strategic Alliance to Co-Develop a Novel Class of

NEW YORK, NY and SALT LAKE CITY, UT, Jun 03 (MARKET
WIRE) —
Aoxing Pharmaceutical Company, Inc. (NYSE Amex: AXN) (“Aoxing Pharma”)
and Phoenix PharmaLabs, Inc. (“PPL”) today jointly announced that the
companies have entered into a co-development, manufacturing and license
agreement related to a novel class of poly-receptor active opioid-like
drug candidates targeting pain and substance abuse and addiction
treatment.

Agreement Highlights

– Aoxing Pharma and PPL entered into a multi-party collaboration
agreement for the development and regulatory approval of a novel class
of therapeutics in both China and ex-China territories. The two
companies will continue to co-collaborate with the U.S. National
Institute of Drug Abuse (“NIDA”) and the Chinese National Institute on
Drug Dependence at Beijing University (“NIDD”).
– Aoxing Pharma received an exclusive license to develop a new class of
poly-receptor active opioid-like drug candidates being developed by
PPL for therapeutic indications in pain management and substance abuse
and addiction treatment in the Country of China, Macau and Hong Kong.
– PPL will receive tiered royalties based on Adjusted Gross Sales (AGS)
in the licensed territories, defined and agreed by both companies.
Aoxing Pharma receives tiered royalties based on Adjusted Gross Sales
(AGS) from the territories held by PPL, defined and agreed by both
companies.
– Aoxing Pharma will execute and fund the development, regulatory
applications, manufacturing and marketing of the licensed drug
candidates in China, while PPL will fund all development in all other
territories.

“We are pleased to announce this global strategic alliance, as one
of our primary goals is to introduce a novel class of therapeutics to
patients around the world with pain or drug addiction problems,” said Dr.
John A. Lawson, Chairman and Chief Executive Officer of Phoenix
PharmaLabs, Inc. “Our drug development program has been funded and
supported by the U.S. National Institute of Drug Abuse (‘NIDA’) for many
years. . We are planning on filing an IND in the U.S. for the first
product candidate early next year. Aoxing Pharma is an emerging leader in
the narcotics and neurological pharmaceutical business in China, which
ideally complements our existing offerings. We view Aoxing Pharma as an
ideal strategic partner given their solid presence and complementary
pipeline.”

“This partnership provides an exciting opportunity to bring in additional
unique product candidates to our growing pipeline for an important market
here in China, while also allowing us to capitalize on potential sales
outside of China,” said Zhenjiang Yue, Chairman and Chief Executive
Officer of Aoxing Pharma. “We believe that this class of new molecules
represents a strong growth opportunity to expand upon our existing
pipeline products in the areas of drug addiction treatment and pain
management, including the sublingual tablet of Buprenorphine/Naloxone,
which is currently under our clinical development and expected to be
launched in China over the next 24 months. With 1.3 million registered
drug addicts and limited pharmacological options available in China,
these new product opportunities have the potential to help serve this
unfortunately rapid growing market.”

About Poly-Receptor Active Opioid-Like Drugs:

Phoenix PharmaLabs’ poly-receptor opioid-like drugs may represent a new
“class” of opioid drugs, with unique pain receptor characteristics never
before seen. PPL believes there are no other opioid drugs with similar
receptor binding profiles. PPL drugs have a unique reduced Mu-receptor
and moderate Kappa receptor activity allowing them to be moderately
active at all three pain receptors. In pre-clinical testing, this
balanced partial activity appears to allow full pain relief potency while
eliminating or reducing such side effects as respiratory depression and
addiction. In short, PPL drugs appear to mimic the natural endorphins in
the healthy brain. For more information, please visit:

http://www.phoenixpharmalabs.com/

About Phoenix PharmaLabs Inc.

Phoenix PharmaLabs, Inc. is a privately held, clinical-stage Utah drug
discovery company focusing on the development and commercialization of
new non-addictive treatments for pain, and new therapies for the
treatment of opiate addiction. The company was founded in 2002 with the
mission to bring its new class of opioid pain therapies and addiction
treatment therapies to the Clinic. For more information, please visit:

http://www.phoenixpharmalabs.com/

About Aoxing Pharmaceutical Company, Inc.

Aoxing Pharmaceutical Company, Inc is a US incorporated specialty
pharmaceutical company with its main operations in China, specializing in
research, development, manufacturing and distribution of a variety of
narcotics and pain-management products. Headquartered in Shijiazhuang
City, outside Beijing, Aoxing has the largest and most advanced
manufacturing facility for highly regulated narcotic medicines. Its
facility is one of the few GMP facilities licensed for the manufacture of
narcotic medicines by the China State Food and Drug Administration
(SFDA). It has joint venture collaboration with Johnson Matthey Plc to
produce and market narcotics and neurological drugs in China. It also has
strategic alliance partnership with QRxPharma and American Oriental
Bioengineering, Inc. For more information, please visit:
www.aoxingpharma.com.

Safe Harbor Statement from Aoxing Pharmaceutical Company, Inc

Statements made in this press release are forward-looking and are made
pursuant to the safe harbor provisions of the Securities Litigation
Reform Act of 1995. Such statements involve risks and uncertainties that
may cause actual results to differ materially from those set forth in
these statements. The economic, competitive, governmental, technological
and other risk factors identified in the Company’s filings with the
Securities and Exchange Commission, including the Form 10-K for the year
ended June 30, 2009, may cause actual results or events to differ
materially from those described in the forward looking statements in this
press release. The Company undertakes no obligation to publicly update or
revise any forward-looking statements, whether because of new
information, future events, or otherwise.

Investor Relations Contact:
Timmy Chou
Vice President, CFO
Tel +1 801 420 0285
Email: tim@phoenixpharmalabs.com

Investor Relations Contact:
Brian Korb
Vice President
The Troup Group LLC
Tel: +1 646 378 2923
Email: bkorb@troutgroup.com

Copyright 2010, Market Wire, All rights reserved.

”Near misses” provoke problem gamblers to gamble more

Washington, May 5 (ANI): Problem gamblers’ brains react more intensely to “near misses” than casual gamblers, possibly prompting them to play more, says a new research.

The study has been published in the May 5 issue of The Journal of Neuroscience.

In the study, researchers found the brain region that responds to rewards by delivering a dose of the chemical dopamine was especially active in these individuals.

Studies have shown that pathological gambling is an addiction, similar in many ways to drug addiction. Now, U.K. researchers Luke Clark, PhD, of the University of Cambridge, and Henry Chase, PhD, of the University of Nottingham find that the degree to which a person”s brain responds to near misses may indicate the severity of addiction.

In the study, the researchers used functional magnetic resonance imaging (fMRI) to scan the brains of 20 gamblers. The participants” gambling habits ranged from buying the occasional lottery ticket to compulsive sports betting.

During the experiment, volunteers used an onscreen slot machine with two spinning wheels of icons. When the two icons matched, the volunteer won about 75 cents, and the brain”s reward pathways became active. An icon mismatch was a loss. However, when the wheels stopped within one icon of a match, the outcome was considered a near miss. Clark and his team found that near misses activated the same brain pathways that wins did, even though no reward was given.

“These findings are exciting because they suggest that near-miss outcomes may elicit a dopamine response in the more severe gamblers, despite the fact that no actual reward is delivered,” Clark said. “If these bursts of dopamine are driving addictive behavior, this may help to explain why problem gamblers find it so difficult to quit.” (ANI)

Drug addiction, a curse for youth in border areas of Punjab

Tarn Taran (ANI), May 4: The problem of drug addiction is steadily assuming alarming proportions in Punjab’s border areas which include many villages adjoining Pakistan.

Several youth, who were expected to take up their traditional agricultural business, are instead, trapped in the drugs’ world.

Though many families are affected by the drugs’ menace, the Punjab Government has done precious little to prevent its trafficking. The worsening condition of the youth highlights the problem.

One can easily get a gram of heroin for rupees 1,000.00, smack for Rs. 300.00 a gram or an injection of morphine for as little as Rs. 25, and that too, without prescription from a medical practitioner.

Not just that, but local drug addicts have given interesting names to name these drugs. “Sharabi Samaan” (Liquor material) is used to denote smack whereas heroin is called “Kishti Samaan” (Boat material).

Synthetic drugs are also in high demand, as any old addict may require as much as over 25 morphine injections for his body.

The case of HIV/AIDS through drug-addiction or using the used syringes is also on increase in the area.

A drug addict for years said that he never wanted to indulge into the menace, but unavoidable family circumstances and his association with bad society pushed him to drug abuse.

“I have studied till XII grade and cleared IELTS. But due to unemployment and family pressure, I took to drugs. I know it is not good for my health but I am helpless,” said a drug addict, requesting anonymity.

He said there were over 50 youth of his village who are into drug addiction. But he said he wished the government could have done something for their rehabilitation in villages.

Admitting to the rise of drug abuse in Punjab, Pritpal Singh Virk, Special Superintendent of Police, Tarn Taran District, said the police have undertaken some initiatives to prevent drug addiction here.

“Police are aware that youth in Punjab are getting into this trade. Punjab Police have also initiated an awareness drive to educate parents and youth about the evils of drug abuse,” Virk said.

About 100 kilometres of the international border area falls in Tarn Taran District, and though there are bleak chances of border-crossing, drug-drop offs are taking place from the Pakistan’s side.

“We will not let anybody who is in this trade to addict youth,” he said.

There are many de-addiction camps being run privately, Government hospitals also have de-addiction centres but they fail to provide results.

Dr. Rana Ranbir Singh, a psychiatrist and in-charge of a government run drug de-addiction center, said that for the last two-and-a-half-years, there has been about 100 percent occupancy at the center, which shows an increase in drug abuse.

He also revealed that most drug addicts belong to the 16 to 35 age group, which indicates the high vulnerability of young people in the border belt.

He, however, said that basically it is a psychological problem and that there is a tremendous need for rehabilitation centers. (ANI)

Technique to visualize ”your brain on drugs” developed

Washington, Apr 27 (ANI): An imaging protocol that allows scientists to visualize the activity of the brain”s reward circuitry in both normal individuals and those addicted to drugs has been developed.

The technique by researchers at the U.S. Department of Energy”s Brookhaven National Laboratory could lead to better insight into why people take recreational drugs as well as help determine which treatment strategies might be most effective.

Drug addiction is a complex process that involves numerous biological and environmental factors, but a central element is how the drugs affect the activity of dopamine, the chemical that regulates pleasure and reward in the brain.

To get a real-time sense of dopamine activity, Joanna Fowler and her colleague Gene-Jack Wang at Brookhaven, along with Nora Volkow, Director of the National Institute on Drug Abuse, combined positron emission tomography (PET), a medical imaging technology useful for identifying brain diseases, with special radioactive tracers that bind to dopamine receptors. The PET scan highlights the movement of the tracers in the brain, and can be used to reconstruct real-time 3D images of the dopamine system in action.

The scientists tested this procedure on several drug-addicted volunteers as well as age-matched healthy control subjects and found that people with addictions in general have 15-20 percent fewer dopamine receptors than normal and thus cannot bind to a lot of the dopamine released in response to the drugs or natural reinforcers like food.

“These addicted individuals all had a blunted dopamine response,” noted Fowler, a senior scientist in Brookhaven”s medical department. “This reinforces the idea that drug addicts experience diminished feelings of pleasure, which drives their continual drug use.”

Fowler added that the study looked at multiple recreational drugs and found similar results. “So, while various drugs operate by unique mechanisms, they all share a commonality in that the dopamine receptors in the brains of addicted individuals show an under-stimulated reward system.”

Fowler noted that Gene-Jack Wang also used the dopamine PET scans on obese individuals and found highly similar patterns of low dopamine receptors–validating that at least in some cases, obesity can also be considered a disease of addiction.

A potential valuable application of observing dopamine activity in real-time, Fowler noted, involves not looking at addicted individuals while they use drugs, but rather when they don”t.

“We can examine individuals as they use different coping strategies to try to suppress their desires for drugs or food,” she said, “and see in the scans which approach work best.” (ANI)

Cousins back as Tigers wield axe

Richmond has declared Ben Cousins ready to return to play again in the AFL as the Tigers became one of several clubs to wield the axe at selection.

The Tigers, Essendon and North Melbourne all underlined how disappointed they were with their efforts last week, by making a raft of changes for important round-three games.

Cousins was one of six changes made for Saturday night’s clash against Sydney at the SCG, as the Tigers dropped Tom Hislop, Jake King, Adam Thomson and Robin Nahas after last Sunday’s thrashing to the Western Bulldogs.

They also lost Will Thursfield and Mitch Farmer to leg injuries.

Richmond’s inclusion of Cousins ended this week’s speculation that the 31-year-old had suffered a relapse in his recovery from a drug addiction.

High-profile player manager Ricky Olarenshaw told a radio station during the week Cousins “may have lost his way again”, which infuriated Richmond.

The Tigers said Cousins did not play the Bulldogs because of knee soreness, and football manager Ross Monaghan said on Thursday night the Brownlow medallist had proven himself ready to return.

“He’s trained fully this week there was never really too much doubt about him playing this week,” Monaghan said.

“But like everyone else he had to get through a week’s training and he’s done that quite comfortably, so there’s no lingering doubts about him playing this week.”

Richmond, which also lost in round one, recalled Shane Tuck, for his first game of the season, Dean Polo, Relton Roberts, Alex Rance and Matthew White.

Sydney is unbeaten and unchanged at selection.

Essendon made six changes for Saturday night’s game against old rivals Carlton at the MCG, by dumping four players after last Sunday’s poor loss to Fremantle.

The Bombers axed Ben Howlett, Brent Prismall, Alwyn Davey and David Myers, and also lost small forward Angus Monfries (quad) and experienced midfielder Mark McVeigh, who remains in hospital battling a virus.

Carlton made just one change, by replacing Joe Anderson with first-gamer Kane Lucas.

North reacted to their 104-point belting to St Kilda by dropping Corey Jones, Ben Ross and Matt Campbell for Saturday’s game against West Coast at Docklands Stadium.

Scott McMahon, Leigh Harding and Aaron Edwards all earned another chance.

Allergies, not drugs, land Houston in hospital

Whitney Houston has slammed media reports that she is using drugs again, labelling the claims “ridiculous”.

Houston was hospitalised in Paris on Tuesday (local time) after suffering a respiratory infection.

On her release, Houston told People magazine that she was looking forward to returning to the stage after postponing several dates on the European leg of her world tour.

“I’m feeling great,” she said. “I’m just ready to move on and continue my world tour.”

The 46-year-old is expected to retake the stage on April 13 in Birmingham, England.

Cancelled shows in Paris, Manchester and Glasgow will be rescheduled.

“My health is terrific, but this is a time when I get a lot of allergies,” she told the magazine.

Houston was once one of the bestselling US female vocalists of all time, but years of battling drug addiction took their toll.

Last year she released I Look To You, her first studio album in seven years to top charts worldwide.

But her performances during a recent tour of Australia were panned by critics and some fans walked out, complaining she was off-key, out of breath and looked exhausted.

The negative reviews and postponed concerts in Europe led some tabloids to speculate that Houston had relapsed into drug use.

She says that is “ridiculous”.

“At this point I just don’t respond,” she told People.

“I don’t even read it.”

Junk food addiction may be clue to obesity – study

Bingeing on high-calorie foods may be as addictive as cocaine or nicotine, and could cause compulsive eating and obesity, according to a study published on Sunday.

The findings in a study of animals cannot be directly applied to human obesity, but may help in understanding the condition and in developing therapies to treat it, researchers wrote in the journal “Nature Neuroscience.”

The study, involving rats, found that overconsumption of high-calorie food can trigger addiction-like responses in the brain and that high-calorie food can turn rats into compulsive eaters in a laboratory setting, the article said.

The scientists also found decreased levels of a specific dopamine receptor — a brain chemical that allows a feeling of reward — in overweight rats, as has been reported in humans addicted to drugs, the article said.

“Obesity may be a form of compulsive eating. Other treatments in development for other forms of compulsion, for example drug addiction, may be very useful for the treatment of obesity,” researcher Paul Kenny of The Scripps Research Institute in Florida said in a telephone interview.

Obesity-related diseases cost the United States an estimated $150 billion each year, according to U.S. federal agencies. An estimated two-thirds of American adults and one-third of children are obese or overweight.

For the study, Kenny and colleagues headed to the grocery store.

“We basically bought all of the stuff that people really like — Ding-Dongs, cheesecake, bacon, sausage, the stuff that you enjoy, but you really shouldn’t eat too often,” he said.

They also bought healthy foods and devised a diet plan for three groups of rats.

One group ate a balanced healthy diet. Another group received healthy food, but had access to high-calorie food for one hour a day. Rats in the third group were fed healthy meals and given unlimited access to high-calorie foods.

The rats in the third group developed a preference for the high-calorie food, munched on it all day and quickly became obese, Kenny said.

The rats in the experiment had also been trained to expect a minor shock when exposed to a light. But when the rats that had unlimited access to high-calorie food were shown the light, they did not respond to the potential danger, Kenny said. Instead, they continued to eat their snacks.

“What we’re seeing in our animals is very similar to what you’d see in humans who overindulge,” he said. “It seemed that it was okay, from what we could tell, to enjoy snack foods, but if you repeatedly overindulge, that’s where the problem comes in.”

JoAnne Allen

Junk food addiction may be clue to obesity: Study

Mon, Mar 29 10:30 AM

Bingeing on high-calorie foods may be as addictive as cocaine or nicotine, and could cause compulsive eating and obesity, according to a study published on Sunday.

The findings in a study of animals cannot be directly applied to human obesity, but may help in understanding the condition and in developing therapies to treat it, researchers wrote in the journal “Nature Neuroscience.”

The study, involving rats, found that over consumption of high-calorie food can trigger addiction-like responses in the brain and that high-calorie food can turn rats into compulsive eaters in a laboratory setting, the article said.

The scientists also found decreased levels of a specific dopamine receptor — a brain chemical that allows a feeling of reward — in overweight rats, as has been reported in humans addicted to drugs, the article said.

“Obesity may be a form of compulsive eating. Other treatments in development for other forms of compulsion, for example drug addiction, may be very useful for the treatment of obesity,” researcher Paul Kenny of The Scripps Research Institute in Florida said in a telephone interview.

Obesity-related diseases cost the United States an estimated $150 billion each year, according to U.S. federal agencies. An estimated two-thirds of American adults and one-third of children are obese or overweight.

For the study, Kenny and colleagues headed to the grocery store.

“We basically bought all of the stuff that people really like — Ding-Dongs, cheesecake, bacon, sausage, the stuff that you enjoy, but you really shouldn’t eat too often,” he said.

They also bought healthy foods and devised a diet plan for three groups of rats.

One group ate a balanced healthy diet. Another group received healthy food, but had access to high-calorie food for one hour a day. Rats in the third group were fed healthy meals and given unlimited access to high-calorie foods.

The rats in the third group developed a preference for the high-calorie food, munched on it all day and quickly became obese, Kenny said.

The rats in the experiment had also been trained to expect a minor shock when exposed to a light. But when the rats that had unlimited access to high-calorie food were shown the light, they did not respond to the potential danger, Kenny said. Instead, they continued to eat their snacks.

“What we’re seeing in our animals is very similar to what you’d see in humans who overindulge,” he said. “It seemed that it was okay, from what we could tell, to enjoy snack foods, but if you repeatedly overindulge, that’s where the problem comes in.”
Reuters

Junk food as addictive as cocaine fix

London, March 29 (ANI): Pigging out on junk food is as addictive as taking heroin and cocaine, according to a new research.

In the new study, scientists from The Scripps Research Institute have shown for the first time that the same molecular mechanisms that drive people into drug addiction are behind the compulsion to overeat, pushing people into obesity.

The study has demonstrated clearly that in rat models the development of obesity coincides with a progressively deteriorating chemical balance in reward brain circuitries.

As these pleasure centers in the brain became less and less responsive, rats quickly developed compulsive overeating habits, consuming larger quantities of high-calorie, high-fat foods until they become obese.

The very same changes occurred in the brains of rats that over-consumed cocaine or heroin, and are thought to play an important role in the development of compulsive drug use.

Scripps Research Associate Professor Paul J. Kenny said that the study, which took nearly three years to complete, confirms the ‘addictive’ properties of junk food.

“It presents the most thorough and compelling evidence that drug addiction and obesity are based on the same underlying neurobiological mechanisms. In the study, the animals completely lost control over their eating behavior, the primary hallmark of addiction. They continued to overeat even when they anticipated receiving electric shocks, highlighting just how motivated they were to consume the palatable food,” Kenny said.

The new research was published March 28, 2010 in an advance online edition of the journal Nature Neuroscience. (ANI)

Junk food addiction may be clue to obesity – study

Bingeing on high-calorie foods may be as addictive as cocaine or nicotine, and could cause compulsive eating and obesity, according to a study published on Sunday.

The findings in a study of animals cannot be directly applied to human obesity, but may help in understanding the condition and in developing therapies to treat it, researchers wrote in the journal “Nature Neuroscience.”

The study, involving rats, found that overconsumption of high-calorie food can trigger addiction-like responses in the brain and that high-calorie food can turn rats into compulsive eaters in a laboratory setting, the article said.

The scientists also found decreased levels of a specific dopamine receptor — a brain chemical that allows a feeling of reward — in overweight rats, as has been reported in humans addicted to drugs, the article said.

“Obesity may be a form of compulsive eating. Other treatments in development for other forms of compulsion, for example drug addiction, may be very useful for the treatment of obesity,” researcher Paul Kenny of The Scripps Research Institute in Florida said in a telephone interview.

Obesity-related diseases cost the United States an estimated $150 billion each year, according to U.S. federal agencies. An estimated two-thirds of American adults and one-third of children are obese or overweight.

For the study, Kenny and colleagues headed to the grocery store.

“We basically bought all of the stuff that people really like — Ding-Dongs, cheesecake, bacon, sausage, the stuff that you enjoy, but you really shouldn’t eat too often,” he said.

They also bought healthy foods and devised a diet plan for three groups of rats.

One group ate a balanced healthy diet. Another group received healthy food, but had access to high-calorie food for one hour a day. Rats in the third group were fed healthy meals and given unlimited access to high-calorie foods.

The rats in the third group developed a preference for the high-calorie food, munched on it all day and quickly became obese, Kenny said.

The rats in the experiment had also been trained to expect a minor shock when exposed to a light. But when the rats that had unlimited access to high-calorie food were shown the light, they did not respond to the potential danger, Kenny said. Instead, they continued to eat their snacks.

“What we’re seeing in our animals is very similar to what you’d see in humans who overindulge,” he said. “It seemed that it was okay, from what we could tell, to enjoy snack foods, but if you repeatedly overindulge, that’s where the problem comes in.”

JoAnne Allen

Junk food addiction may be clue to obesity – study

*Overindulgence may alter brain responses

Stocks | Healthcare

By JoAnne Allen

WASHINGTON, March 28 (Reuters) – Bingeing on high-calorie foods may be as addictive as cocaine or nicotine, and could cause compulsive eating and obesity, according to a study published on Sunday.

The findings in a study of animals cannot be directly applied to human obesity, but may help in understanding the condition and in developing therapies to treat it, researchers wrote in the journal “Nature Neuroscience.”

The study, involving rats, found that overconsumption of high-calorie food can trigger addiction-like responses in the brain and that high-calorie food can turn rats into compulsive eaters in a laboratory setting, the article said.

The scientists also found decreased levels of a specific dopamine receptor — a brain chemical that allows a feeling of reward — in overweight rats, as has been reported in humans addicted to drugs, the article said.

“Obesity may be a form of compulsive eating. Other treatments in development for other forms of compulsion, for example drug addiction, may be very useful for the treatment of obesity,” researcher Paul Kenny of The Scripps Research Institute in Florida said in a telephone interview.

Obesity-related diseases cost the United States an estimated $150 billion each year, according to U.S. federal agencies. An estimated two-thirds of American adults and one-third of children are obese or overweight.

For the study, Kenny and colleagues headed to the grocery store.

“We basically bought all of the stuff that people really like — Ding-Dongs, cheesecake, bacon, sausage, the stuff that you enjoy, but you really shouldn’t eat too often,” he said.

They also bought healthy foods and devised a diet plan for three groups of rats.

One group ate a balanced healthy diet. Another group received healthy food, but had access to high-calorie food for one hour a day. Rats in the third group were fed healthy meals and given unlimited access to high-calorie foods.

The rats in the third group developed a preference for the high-calorie food, munched on it all day and quickly became obese, Kenny said.

The rats in the experiment had also been trained to expect a minor shock when exposed to a light. But when the rats that had unlimited access to high-calorie food were shown the light, they did not respond to the potential danger, Kenny said. Instead, they continued to eat their snacks.

“What we’re seeing in our animals is very similar to what you’d see in humans who overindulge,” he said. “It seemed that it was okay, from what we could tell, to enjoy snack foods, but if you repeatedly overindulge, that’s where the problem comes in.”

Second liver transplant woman recovering

A Perth woman who underwent a live liver transplant to save her life is reported to be progressing well, five days after the operation.

Former drug addict Claire Murray received part of a liver from her aunt Caroline in Singapore last week.

Doctors in Perth refused to place her on a donor waiting list because she received a donor liver last year and relapsed into drug addiction.

The ABC has been told both women continue to recover.

The Aunt is due to be discharged later this week and Ms Murray in about three weeks.

Robbie Williams locking horns with management over tour plans

London, March 22 (ANI): Robbie Williams and his management firm are at odds over plans for a tour at the end of 2010 – while the singer has not made up his mind if he wants to hit the road, bosses are already working out the details of the proposed tour, it has emerged.

Williams, 36, is being asked to promote his latest record Reality Killed the Video Star starting in November, but he has not given a nod to the idea as yet.

“Tempers are fraying because Robbie is non-commital at the moment,” the Sun quoted an insider, as saying.

The source added: “He”s made no secret that he doesn”t want to tour this time round but his management firm, IE Management, are keen to get him out after such a successful comeback.

“He is beginning to come round to the idea but is still unsure.

“People are becoming restless.”

During his last tour in 2006 Williams was struggling with drug addiction and had to cancel a series of gigs.

And he still seems to be unsure if people will watch him perform.

Last week Williams was asking fans at a show organised by Heart radio as part of Heart Love Music Live: “Who wants to see me on tour? I might do one later this year.

“Would any of you come and see me? If I do do it, I won”t be on drugs this time.” (ANI)

Critical period for liver transplant woman

A 24-year-old former drug addict mother who was refused a second liver transplant in Australia has undergone potentially life-saving surgery in Singapore.

Perth woman Claire Murray underwent a 12-hour operation in Singapore last night.

She received part of a liver from her aunt, who is reported to be doing well.

Doctors say it will be 48 hours before they know whether Ms Murray’s liver transplant operation has been successful.

Ms Murray is a former drug addict who was refused a place on a transplant waiting list after she received a donor organ last year before relapsing into drug addiction.

The mother of two young children had been told she only had months to live.

The Western Australian Government agreed to loan Ms Murray’s family $250,000 to pay for the operation.

The Government was criticised over the move, but Premier Colin Barnett defended the decision, saying the loan was a one-off offer.

He said the Government would not be making a habit of lending money for operations.

“The case of the young woman needing a liver transplant is being treated as a one-off situation on its own merits, so any situation would be looked at individually and we’re not about creating precedents,” he said earlier this month.

Richard Buttrose jailed for cocaine dealing

A former Sydney restaurant owner has been jailed for at least twelve and a half years for drug offences.

Richard Buttrose, 37, pleaded guilty to two counts of supplying cocaine to an undercover officer and another charge relating to six kilograms of the drug which were found in his unit.

The cocaine in his unit had a street value of around $10 million.

In sentencing Buttrose a District Court judge said cocaine is a highly dangerous drug and that the social cost of drug addiction to the community is high.

Buttrose previously told the court that he started using cocaine to cope with the pressure of running his restaurant chain.

He said when he was selling it, he liked being known as ‘The Man.’

Buttrose winked at members of his family in the court just before he was sentenced.

They included his aunty, the Sydney media identity, Ita Buttrose.

Outside the court Detective Senior Constable Craig Partridge welcomed the sentence.

“It was a large-scale retail drug operation,” he said.

“We are very happy with the outcome.”

The court heard that Buttrose is in protective custody in jail. With time already served, he will be eligible for parole in 2021.

Family members refused to comment on the sentence to media waiting outside the court.

Presley’s ex-bodyguard co-producing tell-all biopic

Washington, September 15 (ANI): Rock ‘n’ roll legend Elvis Presley’s former bodyguard is all set to reveal how his life used to be during his time with the tragic entertainer in a new biopic.

Sonny West will talk about Presley’s sensational rise to fame, his tragic demise, and struggle with drug addiction in feature-length film ‘Fame and Fortune’.

He will be a co-writer and co-producer of the film, reports Contactmusic.

According to Daily Variety, he has signed a deal with Toronto-based film company RLF Victor Productions in this regard.

West was employed by Presley from 1960 until 1976, one year prior to the star’s tragic death after suffering a heart attack. (ANI)

Deepak Chopra says MJ was “a very controlled addict”

London, Sept 14 (ANI): World-famous self-help guru Deepak Chopra believes his friend Michael Jackson could not have died of drug addiction, as he was a “very controlled addict”.

The Telegraph quoted Chopra as saying: “It was caused not by the drugs he had been taking for years…. He was a very controlled addict. But by him being given a particular drug that is so powerful that I have never heard of it being used anywhere but in an operating theatre with breathing tubes and a ventilator.”

Chopra, who is also called “the spiritualist to the stars”, wants a criminal investigation into the King of Pop’s death and blames doctors for his easy demise.

He said: “There is a plethora of designer doctors who will give patients anything they want as along as they are paid…. That’s why I’d like to see a criminal investigation. That way some good would come out of Michael’s death. But no one seems to be prepared to do anything about it – even when the drugs these doctors are prescribing are killing people.”

MJ had contacted Chopra after reading one of his books on mind, body and spirit and the two had always been in touch since then. (ANI)

‘Mysterious messages’ penned by MJ in final hours emerge

London, September 13 (ANI): A string of messages penned by Michael Jackson in his final hours have come to light.

Post-its notes and sheets of paper, scribbled as “wishes for the world” have reportedly been found on the mirror in the late singer’s bathroom.

The notes allegedly show the King of Pop’s bizarre state of mind before he died of drug addiction on June 25, reports the News of the World.

Pals of the singer believe Jackson was using the notes as means to prepare himself for his comeback concerts in London.

Note number one, found on the right of Jackson’s gold-framed mirror, apparently read: “I am so grateful that I am a magnet for miracles.”

Note number two, pinned to the bottom of the mirror, a message in large handwriting said: “Love, no violence ever!” And underneath, in smaller handwriting, he had added: “Remember a beautiful future promise of tomorrow.”

Note number three was a startling reminder to perform the hit charity single he recorded with soul legend Lionel Ritchie in 1985, saying: “Do We Are The World in show”.

Note number four read “Call Temperton”, referring to British songwriter and producer Rod Temperton, who co-wrote several Jackson songs including Thriller and Rock With You.

A source said: “It’s worrying that he had to write reminders about things as obvious as these while he was rehearsing for his tour…But the drugs he was taking obviously had a huge impact on his mind and memory.” (ANI)