UPDATE 3-Sumitomo buys stake in Usiminas unit for $1.93 bln

SAO PAULO, July 1 (Reuters) – Usiminas (USIM5.SA), Brazil’s largest maker of flat steel, said on Wednesday it is selling 30 percent of its mining unit to Japan’s Sumitomo Corp (8053.T) for $1.93 billion, in a bid to raise cash to develop its fast-growing iron ore assets.

Sumitomo agreed to subscribe for new shares of the unit, called Mineracao Usiminas (MUSA), as part of the deal, Usiminas said in a filing with Brazil’s securities regulator.

Sumitomo will pay $1.35 billion by the end of August and the rest upon confirmation of the mine’s expansion plan and the quality of the ore, Sumitomo told reporters in Tokyo.

By bringing in Japan’s third-biggest trading house as a partner, Usiminas Chief Executive Wilson Brumer, who took over in April, will likely mitigate potential risks in developing iron ore assets, unlocking value for shareholders.

Iron ore prices have more than doubled this year, forcing steelmakers to rely more on their own mining assets to avert violent price swings.

“We are creating the necessary conditions to fund the growth of the mining operations without crowding out potential funding for the steel arm,” Brumer told investors on a conference call on Wednesday.

Usiminas and Sumitomo are expected to seal terms of the transaction by the end of August, the filing added.

Usiminas expects to invest up to 4 billion reais ($2.2 billion) by 2015 to develop its iron ore assets, Brumer said. Recent geology studies indicated that Usiminas mines have potential reserves of 2.6 billion tonnes of the mineral, he noted.

Usiminas is trying to replicate a strategy by rival CSN (CSNA3.SA) (SID.N), which earlier last decade invested heavily in its mines to reduce dependence on third parties for supply of the mineral.

Brazil’s iron ore is globally known for its superior quality, allowing steelmakers based here to charge a premium on some Brazilian-made products or sell the mineral to other customers.

The Belo Horizonte, Brazil-based company will also transfer assets and issue new shares of Mineracao Usiminas and Usiminas Participacoes e Logistica, its logistics unit, as part of a plan to boost their value, the filing said.

Under the project, MUSA’s iron ore output is expected to reach 8 million tonnes next year, up from this year’s 7 million tonnes. Usiminas and Sumitomo aim to expand the output to as much as 29 million tonnes by 2014 or 2015, Sumitomo said.

“Our investment in the project could generate 10 billion yen to 20 billion yen ($110-230 million) profit annually when expansion plans are completed,” Kuniharu Nakamura, Sumitomo’s senior managing executive officer, told a news conference.

Shares of Usiminas fell for a second day, shedding 0.9 percent to 49.28 reais. The stock has risen less than 1 percent this year, compared with a drop of about 4 percent in shares of rival CSN, Brazil’s second-largest maker of flat steel.

The Sumitomo stock inched up by 0.2 percent to 899 yen on Thursday, bucking a 2 percent fall in the broader Tokyo market. ($1=88.38 Yen) (Additional reporting by Yuko Inoue in TOKYO, Brian Ellsworth in SAO PAULO; Editing by Muralikumar Anantharaman)

Krishna’s US visit starts from June 1

With the Obama administration keen to elevate its dialogue with New Delhi, external affairs minister SM Krishna will leave for the US for the first ministerial-level strategic dialogue.

The three-day strategic dialogue from June 1, will be co-chaired by US secretary of state Hillary Clinton. The talks between Krishna and Clinton are also expected to lay the ground for US President Barack Obama’s visit to India later this year. Krishna will be accompanied by several senior ministers, including HRD minister Kapil Sibal, deputy chairman of Planning Commission Montek Singh Ahluwalia and foreign secretary Nirupama Rao, and other senior officials.

While strategic talks between the two democracies have taken place, this will be the first ministerial-level dialogue. US administration is keen on transforming relations and expanding ties in key sectors such as education, agriculture and space. It has already completed strategic talks with China and Pakistan. While the focus of the talks will be bilateral, regional issues will also be high on the agenda. Terrorism and Af-Pak will be on the table. Clinton needs to reassure Krishna that the US is not tilting towards Pakistan because of its dependence on its Army.

Referring to the inaugural India-US strategic dialogue led by Krishna and Clinton, State Department spokesman P J Crowley said at a briefing, “I think the strategic dialogue speaks for itself. We have very strong cultural ties to India, so we look forward to the strategic dialogue.”

U.S. diners plan to cut restaurant meals spending

LOS ANGELES, May 4 (Reuters) – U.S. consumers are eating out more frequently, but plan to spend less on each meal, according to a study released on Tuesday by advisory firm AlixPartners.

Consumers surveyed in late March said they planned to spend about $11.60 per restaurant meal over the coming 12 months — down 21 percent from 2008 and 4 percent lower than last year.

Restaurants, which have seen traffic stabilize after the recession spawned steep declines, also are bracing for higher food costs later this year.

“Despite some stabilization of late, the restaurant industry is by no means out of the woods,” said Andy Eversbusch, a managing director at AlixPartners and head of the firm’s restaurant and food service practice.

“Sales will continue to be pressured by growing price sensitivity among virtually all consumers, regardless of the types of restaurants they visit,” Eversbusch said.

Lower food costs made it easier for all restaurants to offer discounts in 2009.

The Subway chain grabbed headlines with its $5, foot-long sandwich deal that established the second-most important restaurant price point since McDonald’s Corp (MCD.N) introduced its Dollar Menu in 2002. [ID:nN17480279]

The expected decline in restaurant spending was due in part to the “Subway Effect,” said Eversbusch.

“This will be another year of deals. It has to be,” Adam Werner, a director at AlixPartners, told Reuters.

But not every operator feels that way.

Chili’s Grill & Bar parent Brinker International Inc (EAT.N) said in April it planned to lessen its dependence on discounts.

Chili’s featured a “3 for $20″ deal offering two entrees and both an appetizer and a dessert to split between two diners. The promotion initially cut into margins but eventually drew enough diners to have a positive effect.

Brinker’s sentiment is becoming more prevalent as food costs creep up and threaten to squeeze operators that depend on discounts.

AlixPartners director Adam Fless said companies can insulate themselves by doing things like adding high-margin products to menus, improving service and investing in growth markets like China, India and Brazil. (Reporting by Lisa Baertlein, editing by Leslie Gevirtz)

Antony calls upon industry to boost ship building programmes of Indian Navy

Mumbai, Apr.29 (ANI): Defence Minister A K Antony on Thursday called upon the Indian Industry to give their best in developing the country’s ship building programmes.

Speaking after commissioning INS Shivalik, the first of three new indigenous stealth frigates here, Antony said over the years there has been a distinct shift in country’s policy from a “Buyer’s Navy’ to a ‘Builder’s Navy”.

He stressed that the ship building industry has to modernize itself through indigenous efforts and minimize its dependence on imports.

“We must continue with our efforts to transform and modernize our shipyards, so that they can not only meet the domestic demands but also achieve latest international standards in quality construction. We must be able to produce quality ships in a shorter time frame at competitive costs. I strongly urge all the participants of the Indian industry to give their best in developing our ship building programmes,” Antony said.

He pointed out that the security situation in and around India’s immediate neighbourhood poses several security related challenges, adding there is a need to maintain high levels of operational readiness at all times.

Described the commissioning of INS Shivalik, the largest stealth frigate in the world, as a red letter day for the Indian Navy, Armed Forces, the ship building industry and the entire nation, Antony said India’s long coastline and ever expanding exclusive economic zone make it imperative to defend main land as well as maintain the sea lanes of communication.

INS Shivalik and the follow-on-ships of the Shivalik class (namely, Satpura and Sahyadiri) have been conceived and designed by Indian Navy design teams. The Shivalik class will be the mainstay frigates of the Indian Navy in the first half of the 21st century. (ANI)

Diversify or die: economists warn on mining dependence

The Finance Minister, Lindsay Tanner, has warned that Australia needs to reduce its reliance on mining by revitalising other export industries.

He told ABC local radio that he was worried that a former expansion in tourism, education and wine exports had gone into reverse.

Lindsay Tanner was asked whether Australia’s economy is too dependent on China. This is what he said:

“I wouldn’t so much say China but I would say that we do need to reinvigorate the breadth of our exports,” he told ABC radio 774 in Melbourne.

“We have had a worrying period over the past decade or so where the diversification of our exports in the ’90s kind of stagnated.

“So we had a huge growth in tourism, in education, in specialised manufacturing, in wine, in pharmaceuticals – all kinds of things that helped us to diminish our enormous reliance on minerals, and that’s kind of almost gone into reverse in recent times.

“So it’s not so much that there’s one country that we’re dependent on. It’s that we have I think to some extent too many eggs in that basket.”

The Finance Minister says Australia needs to diversify its exports.

“Minerals are always going to be critical for Australia. There’s no question about that,” he added.

“But our strategy of improving infrastructure and skills and lifting out productivity very much has in mind the need to revive our performance in some of our other exports which have been languishing.”

Dollar damage

What the Finance Minister did not say is that the decline in the export industries that boomed in the 1990s has gone hand in hand with the boom in mining.

“One of the corollaries of the present mining boom is a very high value of the Australian dollar that is hurting the competitiveness of sectors such as agriculture, manufacturing, tourism and education,” said Saul Eslake, the director of the Productivity Growth Program at the Grattan Institute, a policy think tank affiliated with Melbourne University.

“Although the mining industry is generating a lot of prosperity for Australians at the moment, and will do in the foreseeable future, nonetheless the mining industry can’t possibly guarantee prosperity for the vast majority of Australians given that it accounts for less than 3 per cent of total employment.”

Warren Hogan succeeded Saul Eslake as chief economist at the ANZ Bank and he shares his concerns.

“Our real effective exchange rate is at a 30 year high, and this, of course, is a major constraint strategically on this economy,” he explained.

“When you have a commodity boom that drives up your currency because you’re seeing certain of your exports go up in price it puts pressure on other sectors.

“Manufacturing but, I think more importantly in Australia’s case, I’m worried about tourism and I’m worried about education exports. This is the classic Dutch disease. And you know I don’t think many Australians would be happy to think that all we sell is iron ore and coal.”

The term Dutch disease was coined in the 1970s. It described the effect of a huge natural gas reserve discovered in the 1950s which drove up the currency and killed Dutch manufacturing.

It has become synonymous with mineral booms that destroy other export sectors, and it is a real risk for Australia.

“The mining boom, though it may well go on for more than a decade, isn’t going to go on indefinitely any more than previous mining booms have,” Mr Eslake added.

“Future generations of Australians are going to look for other sectors of the economy for their employment prospects long after this present mining boom has come to an end.”

The danger is they will no longer be there by the time the mining boom ends and the currency edges lower.

Industry policy revival?

Frank Gelber, the chief economist with forecasting firm BIS Shrapnel told PM last week that, without intervention, Australia risks becoming a quarry.

“We’re running down the rest of the economy. We’re specialising in minerals, and this is all very nice when we’ve got very high minerals prices and very strong demand,” he said.

“But minerals prices don’t always boom and demand isn’t always strong. The lessons of the last 50 years should have taught us that.”

He is calling on the Federal Government to resurrect unfashionable ideas such as industry policy to help other sectors survive.

“What we need to do is to try to impede the demise of the other tradables industries. Does it mean some sort of an industry policy again? Yes it does.”

However, that concept is anathema to the Department of Treasury.

Back in 2006 the Treasury Secretary, Ken Henry, predicted a commodities super cycle lasting up to 50 years.

He said it would see capital labour relocate to the mining states, enriching those areas and stripping wealth from others, and government policy should be judged on whether or not it backed the trend.

“Proposals that seek to resist the changes should themselves be resisted,” Dr Henry said.

Lindsay Tanner is not talking about resisting the mining boom, and he is not using the phrase “industry policy”.

But if the government wants to maintain a diverse economy and a diverse export base it will have to start asking some hard policy questions, and it may have to buck the Treasury line.

Coming soon, cars powered by dirty nappies, food scraps

Sydney, Mar.24 (ANI): Australia’s most popular car the General Motors (GM) Holden could soon be seen running on daily household garbage, including dirty nappies and food scraps, as the car company has formed a consortium with Caltex, the Victorian Government and three other technology companies to explore the viability of an ethanol plant that would convert household rubbish into fuel.

The plant is likely to be set-up in Melbourne, which will use GM partner Coskata’s technology to produce more than 200 million litres of ethanol a year from household rubbish and building waste for E85 automotive fuel, a blend of up to 85 per cent ethanol and 15 per cent petrol.

The ethanol plant would take two years to build and would be capable of producing 200 million litres of ethanol a year from a variety of waste, including building materials, paper, cardboard and household food scraps.

Talking about the ambitious plan, Holden”s energy and environment director, Richard Marshall said the technology would greatly reduce Australia’s dependence on conventional and foreign fuel and would be eco-friendly as well.

“Our vision is that this technology will, in time, cut Australia”s dependence on petrol by up to 30 per cent and make a contribution to sustainable motoring and greenhouse gas reduction,” The Sydney Morning Herald quoted Marshall, as saying.

“This process can use anything from dirty nappies to food scraps,” he said.
(ANI)

Few Malaysian takers for restaurants jobs

Kuala Lumpur, Mar. 24 (ANI): There are very few Malaysians who want to work in restaurants, with only 180 nationals applying for 25,000 jobs offered by the Malaysian Muslim Restaurant Operators Association (Presma).

The Star Online quoted Presma Deputy President Kadhar Shah Abdul Razak as saying that out of 180 of those who applied, only 40 Malaysians were employed.

He added that Presma wanted all the positions filled by Malaysians to reduce dependence on foreign workers.

Razak further said that those interested could still attend walk-in interviews at the restaurants. (ANI)

Smoking, not history of alcohol abuse, ”impairs mental function”

Washington, Mar 16 (ANI): A new study suggests that men and women with a history of alcohol abuse may not see long-term negative effects on their memory, but female smokers do.

In a study, which involved 287 men and women aged 31 to 60, researchers found that those with past alcohol-use disorders performed similarly on standard tests of cognitive function as those with no past drinking problems.

However, the findings were not as positive when it came to tobacco.

In general, women who had ever been addicted to smoking had lower scores on certain cognitive tests than their nonsmoking counterparts. The same pattern was not true of men, however, the researchers report in the March issue of the Journal of Studies on Alcohol and Drugs.

The reasons for the disparate findings on alcohol and smoking are not fully clear. Nor do they necessarily mean that serious alcohol problems would not affect long-term memory and other cognitive abilities; most study participants who had ever had drinking problems met the criteria for alcohol abuse rather than the more serious diagnosis of dependence.

Alcohol abuse was diagnosed when people reported one symptom of problem drinking — drinking and driving, for instance, or failing to meet work or school obligations as a result of drinking. Dependence, on the other hand, required people to have at least three symptoms — such as needing to drink more and more to achieve the same effects and experiencing physical withdrawal symptoms when they did not drink.

If more study participants had been alcohol dependent, the findings on cognition might have been different, says lead researcher Dr. Kristin Caspers, an assistant research scientist in the department of psychiatry at the University of Iowa in Iowa City.

But the bottom line, she says, is that people with a history of alcohol abuse appear not to be “doomed” to suffer cognitive effects when current levels of drinking are in the light to moderate range. (ANI)

Young age at first drink can turn under-15s into alcoholics

Washington, Sept 19 (ANI): Drinking at young age may affect genes linked to alcoholism and make youngsters vulnerable to severe problems, says a new study.

The study led by Dr Arpana Agrawal, from Washington University School of Medicine in St. Louis, revealed that the younger an individual was at first drink, the greater the risk for alcohol dependence and the more prominent the role played by genetic factors.

“There seemed to be a greater genetic influence in those who took their first full drink at a younger age,” said Agrawal.

“That’s very consistent with what has been predicted in the literature and in the classification of types of alcohol dependence, but we present a unique test of the hypothesis,” she added.

During the study, the researchers studied 6,257 adult twins from Australia and measured the extent to which age at first drink changed the role of heritable influences on symptoms of alcohol dependence.

The study showed that when twins started drinking early, genetic factors contributed greatly to risk for alcohol dependence, at rates as high as 90 percent in the youngest drinkers.

The team also found that those who were 15 or younger when they started drinking tended to have a greater genetic risk for alcohol dependence.

However, some who were 16 or older before they took their first drink later became alcohol dependent, but their dependence was related more to environmental factors.

“Something about starting to drink at an early age puts young people at risk for later problems associated with drinking,” Agrawal says.

“We continue to investigate the mechanisms, but encouraging youth to delay their drinking debut may help.

“Some early-onset drinkers do not develop alcohol problems and some late-onset drinkers do – we are working on why that is the case, but it is important to note that this is one risk factor among many and does not determine whether a person will, or will not, develop alcohol dependence.

“But age at first drink is a well-known risk factor, and there have been two main hypotheses about why:

One has been that common genetic and environmental factors contribute both to the risk for alcohol dependence and to the likelihood a person will be younger when consuming their first drink,” she added.

The study will be published Alcoholism: Clinical and Experimental Research. (ANI)

Catalyst simulations for fuel cells may make clean cars a reality

Washington, Sep 18 (ANI): University of Wisconsin-Madison researchers are working towards developing better catalyst for fuel cells in a bid to make clean cars a reality.

If successful, the researchers could make a car that runs on hydrogen from solar power, and produces water instead of carbon emissions.

Materials science and engineering assistant professor Dane Morgan and Ph.D. student Edward (Ted) Holby have developed a computational model that could optimise an important component of fuel cells, making it possible for the technology to have a more widespread use.

The researchers investigated how particle size is related to the overall stability of a material, and showed with their model that increasing the particle size of a fuel cell catalyst decreases degradation and therefore increases the useful lifetime of a fuel cell.

Fuel cells are electrochemical devices that facilitate a reaction between hydrogen and oxygen, producing electrical power and forming water.

In the type of fuel cells Morgan is researching, called proton exchange membrane fuel cells (PEMFCs), hydrogen is split into a proton and electron at one side of the fuel cell (the anode).

The proton moves through the device while the electron is forced to travel in an external circuit, where it can perform useful work, while at the other side of the fuel cell (the cathode), the protons, electrons and oxygen combine to form water, which is the only waste product.

One of the many hurdles to producing efficient fuel cells for widespread use is the catalyst added to aid the reaction between protons, electrons and oxygen at the cathode.

Current fuel cells use platinum and platinum alloys as a catalyst. While platinum can withstand the corrosive fuel cell environment, it is expensive and not very abundant.

Thus, to maximize platinum use, researchers use catalysts made with platinum particles as small as two nanometers, which are approximately 10 atoms across.

These tiny structures have a large surface area on which the fuel cell reaction occurs.

However, platinum catalysts this small degrade very quickly, which means that the fuel cell doesn’t last long.

The researchers have found a possible solution to the rapid degradation problem-when it comes to catalyst particle size, sometimes smaller isn’t better.

In their modelling work, they showed that if the particle size of a platinum catalyst is increased to four or five nanometers, which is approximately 20 atoms across, the level of degradation significantly decreases.

This means the catalyst and the fuel cell as a whole can continue to function for much longer than if the particle size was only two or three nanometers.

“Fuel cells are just one of many energy technologies – solar, battery, etc. – with enormous potential to reduce our dependence on oil and our carbon emissions. Computer simulation offers a powerful tool to understand and develop new materials at the heart of these energy technologies,” said Morgan. (ANI)

Rajasthan Government demands lion’s share in Cairn project

Barmer (Rajasthan), Aug.29 (ANI): The Government of Rajasthan on Saturday demanded a lion’s share of the value added tax (VAT) that would be generated from the extraction of crude oil from the Mangala Processing Terminal ( MPT) here.

According to sources, the issue will be settled later when state government representatives meet the officials of this Cairns Energy India-ONGCjoint venture.

ONGC Chairman R.S. Sharma said that it would take at least four years to meet this demand of the Rajasthan Government, which was made by Chief Minister Ashok Gehlot. Sharma said that the approach of the state government would determine the way forward on the issue of revenue sharing.

Officials attached with the joint venture said they are leaving no stone unturned in doing their bit for the local people.

The media contingent accompanying the Prime Minister, Dr. Manmohan Singh, on the inaugural visit to the project site were shown the entrepreneural centre where various social projects for local people are showcased.

Cairn India CEO Rahul Dhir emphasised the point that the maximum number of labourers are locals, and added that out of the 700 contractors, a majority are local people.

Inaugurating the project, Dr. Singh said the present venture is an indication that foreign investment in the country will grow and that the Indian Government will honestly provide all facilities to attract foreign investment.

He also congratulated the technical personnel for successfully finding oil reserves.

It maybe recalled that the Dutch firm Shell had abandoned the search for oil in this desert area. cairn india then stepped in, and after four years of continuous labour, was able to discover oil. arlier, Petroleum and Natural Gas Minister Murli Deora described the activation of the Mangala Processing Terminal ( MPT) as a historic achievement, as the crude oil production from this block will meet about 20 percent of the nation’s current crude oil production.

He said this will enable the country to save seven percent of the crude oil import bill and reduce import dependence.

Deora also emphasised the need for stabilising crude oil prices for ensuring the sustained economic growth of the country, Deora said the MPT find is a significant step towards achieving this goal.

Cairn has invested about Rs.10000 crores in the area.

The total investment in this project will be more than Rs. 20000 crores. The government will get Rs. 46000 crores as profit petroleum revenue over the life of the project and will provide job opportunities for more than 6000 people.

According to company sources, the supply terminal to the Mangala field, the second largest oil discovery in the country in two decades, will be a giant step towards curtailing the country’s oil import bill.

With an initial 30,000 barrels capacity per day (bpd), Cairn India plans to add another 1,00,000 bpd over the next 18 months.

Mangala oil field officials are confident of reaching the target of producing 1,75,000 bpd in the next 20 months.

The project would contribute more than 20 per cent of India’s domestic crude oil production by 2011, the company sources said. By Pankaj Chaudhary (ANI)

Dayanidhi Maran to lead joint trade delegation to Japan

New Delhi, July 16 (ANI): Union Textiles Minister Dayanidhi Maran will lead the joint trade delegation of textiles sector to Japan on July 20.

The seventeen-member delegation comprises the representatives of the Apparel Export Promotion Council (AEPC), The Cotton Textiles Export Promotion Council (TEXPROCIL), the Synthetic and Rayon Textiles Promotion Council (SRTEPC), the Knitwear Technology Mission, and leading textiles manufacturers and exporters from Tirupur and Coimbatore textiles clusters.

During his visit, Maran will inaugurate the Indian Pavilion at the Japan International Fashion Fair (JIFF), known as Mega Apparel and Textile Show, at Tokyo, Japan on July 22.

The Fair will run till July 24, and 44 Indian textiles and clothing exporters have booked 50 stalls. The AEPC along with the SRTEPC and the TEXPROCIL are participating in the Fair.

With a view to diversify the textiles and clothing exports and reduce dependence on USA and EU 27, the Government is promoting exports to South East Asia under its ‘Look East Policy’.

An important component of this policy is to attract of Foreign Direct Investment (FDI). Japan is one of the biggest consumers of textiles and clothing, but India has very negligible market share of 1.12 per cent in Japanese import basket.

To further these objectives, during his stay in Tokyo, Maran will address a business meeting hosted by the Japan-India Business Cooperation Committee (JIBC) and will use this platform to solicit investment in Indian textiles sector, where 100 per cent FDI is permissible.

The Indian Government is conscious of the fact that textiles industry needs modernization and there is huge scope for Japanese investment to upgrade spinning, weaving, processing and garmenting facilities.

The Government is making serious efforts to attract investment in this important segment of national economy. This interaction is part of series of interactions, which Maran has conceptualized as part of Government efforts to modernize Indian textiles industry and explore new markets for Indian textiles and clothing exports.

In addition, Maran will meeting Takeo Yamaoka, Chairman , JUKI Corporation , the largest sewing machine manufacturer and Akira Onishi, Chairman , Kirloskar Toyota, the leading Japanese textiles machinery manufacturer. (ANI)

Family history may help predict severity of mental disease

Washington, July 7 (ANI): Researchers from Duke Institute for Genome Sciences and Policy (IGSP) have revealed that family history can play a vital role in predicting the severity of mental disorder.

They suggest that just 30 minutes or less of question-and-answer about the family history of depression, anxiety, or substance abuse is enough to predict a patient’s approximate risks for developing each disorder, and how severe their future illness is likely to be.

“There are lots of kids with behaviour problems who may outgrow them on their own without medication, versus the minority with mental illnesses that need treatment,” said Terrie Moffitt, a professor of psychology and neuroscience in the IGSP.

“Family history is the quickest and cheapest way to sort that out,” she added.

Co-researcher Avshalom Caspi, professor of psychology and neuroscience, added that researchers searching for genes responsible for mental disorders might also take advantage of the discovery.

During the study, the researchers examined 981 New Zealanders, who were a part of Dunedin Study.

They tested each individual’s personal experience with depression, anxiety, alcohol dependence and drug dependence in relation to their family history “scores” – the proportion of their grandparents, parents and siblings over age 10 who were affected.

The analysis shows that family history can predict a more recurrent course of each of the four disorders. It is also indicative of those more likely to suffer a worse impairment and to make greater use of mental health services.

Family history could be used to identify those in need of early intervention or more aggressive treatment.

The findings appear in the Archives of General Psychiatry. (ANI)

New discovery to pave way for novel treatments of alcohol dependence

Washington, July 1 (ANI): Scientists have identified a brain mechanism linked with alcohol addiction that involves the stomach hormone ghrelin, a discovery that may lead to new therapies for addictions like alcohol dependence.

The researchers at the Sahlgrenska Academy, Gothenburg, have observed that blocking ghrelin’s actions in the brain can reduce alcohol’s effects on the reward system.

Ghrelin is a hormone produced by the stomach and, by signalling in the brain, it increases hunger.

Its involvement in alcohol addiction highlights the reward system of the brain as a key target for ghrelin’s effects.

“Ghrelin’s actions in the brain may be of importance for all kinds of addictions, including chemical drugs such as alcohol and even food,” said Suzanne Dickson, Professor of Physiology, a leading expert in appetite regulation.

The researchers showed that mice treated with ghrelin increase their alcohol consumption.

When ghrelin’s actions are blocked, for example, by administering ghrelin receptor antagonists, mice no longer show preference for an alcohol-associated environment.

This means that alcohol is no longer able to produce its addictive effects that include reward-searching behaviour (similar to craving in alcoholic patients).

“If we can develop drugs that block the receptors for ghrelin, we could have a new effective treatment for alcohol dependence. It may however take several years until such a pharmacological treatment will reach the patient”, said a co-author of the study.

Alcohol dependence is a complex and chronic disease that leads to adverse consequences affecting not only the patient but also their immediate family, and it also has a profound economic burden on society.

The results of the study will be published in the renowned American scientific journal Proceedings of the National Academy of Sciences (PNAS). (ANI)

Scientists identify alcohol-binding site in the brain

London, June 29 (ANI): Scientists at the Salk Institute for Biological Studies have a step closer to understanding how alcohol alters the way brain cells work.

The researchers say that they have identified a binding site for alcohol in an ion channel that plays a key role in several brain functions associated with drugs of abuse and seizures.

They believe that their results could lead to the development of novel treatments for alcoholism, drug addiction, and epilepsy.

Ethanol, the alcohol in intoxicating beverages, is known to alter the communication between brain cells.

“There’s been a lot of interest in the field to find out how alcohol acts in the brain,” Nature magazine quoted Dr. Paul A. Slesinger, an associate professor in the Peptide Biology Laboratory at the Salk Institute, as saying.

“One of several views held that ethanol works by interacting directly with ion channel proteins, but there were no studies that visualized the site of association,” added the lead researcher.

He says that his study has shown that alcohols directly interact with a specific nook contained within a channel protein.

According to him, this ion channel plays a key role in several brain functions associated with drugs of abuse and seizures.

In their previous research, Slesinger’s team focused on the neural function of these ion channels, called GIRK channels, which open up during periods of chemical communication between neurons and dampen the signal, creating the equivalent of a short circuit.

“When GIRKs open in response to neurotransmitter activation, potassium ions leak out of the neuron, decreasing neuronal activity,” says UCSD Biology graduate student and first author Prafulla Aryal.

While alcohols have been previously shown to open up GIRK channels, no study ever determined whether this was a direct effect or whether this was the by-product of other molecular changes in the cell.

The researchers say that the identification of the location of a physical alcohol-binding site important for GIRK channel activation could point to new strategies for treating related brain diseases.

They believe that this protein structure may be used to develop a drug that antagonizes the actions of alcohol for the treatment of alcohol dependence.

“(Alternatively) If we could find a novel drug that fits the alcohol-binding site and then activate GIRK channels, this would dampen overall neuronal excitability in the brain and perhaps provide a new tool for treating epilepsy,” says Slesinger.

A research article describing the study has been published in the journal Nature Neuroscience. (ANI)

Nicotine dependence remains steady despite decline in cigarette use

Washington, June 25 (ANI): Although the number of people taking up smoking has declined following rigorous efforts, nicotine dependence has remained steady among adults, according to a new study.

The research led by Columbia University Mailman School of Public Health researchers has shown that nicotine dependence has actually increased among some groups.

Previous studies have found that since the 1964 U.S. Surgeon General report, the number of people who smoke cigarettes has declined. The Mailman School of Public Health study takes this research a step further by distinguishing occasional smokers from heavy smokers.

“Regular, heavy cigarette use frequently characterizes nicotine dependence and is the pattern of use thought to be the most detrimental to health and longevity, but it has not been addressed in previous estimates of the decline in smoking prevalence,” said Dr Renee Goodwin, associate professor of Epidemiology at the Mailman School of Public Health and principal investigator of the study.

“Rather, earlier research mainly addressed tobacco use or cigarette smoking per se rather than examining the frequency and duration of cigarette use in detail,” she added.

The new study finds not only that the number of nicotine-addicted Americans has held steady over the past several decades, but also that the proportion of cigarette smokers who are addicted to nicotine nowadays is greater than in previous generations.

Dr. Goodwin suggests that fewer people are taking up smoking, perhaps because of anti-cigarette campaigns, leaving the ranks of current smokers filled with the nicotine dependent.

It is also thought that socioeconomic status is a factor in cigarette use. The current study finds that younger women living in poverty had the highest rates of nicotine dependence, compared with older generations, and those not living in poverty.

This suggests that despite increases in taxes and smoking costs, those most vulnerable are still heavily affected.

The study appears in American Journal of Public Health. (ANI)

Biden teases Obama over teleprompter dependence

Colorado (US), May 28 (ANI): Vice President Joe Biden teased his boss President Barack Obama on Wednesday over his teleprompter dependence.

Speaking at the Air Force Academy commencement ceremony in Colorado, Biden poked fun at Obama’s known affinity for his teleprompter.

Biden made the crack about Obama’s crutch after a strong gust of wind blew over one of the vice president’s teleprompters.

Fox News quoted Biden as saying then: “What am I gonna tell the president when I tell him his teleprompter is broken? What will he do then?”

The crowd laughed at the joke made at the expense of the absent president, who was in Las Vegas at the time.

Luckily for Biden, one teleprompter was still standing and the mishap was toward the end of his remarks. He recovered and thanked the cadets for their service to their country. (ANI)

Fighting parents make kids more prone to mental health problems in later life

Washington, May 28 (ANI): People with parents who fight are more likely to have mental health problems in later life, a new study has found.
n the study, published in the Journal of Epidemiology and Community Health, researchers looked at what impact interparental violence had on people as children by observing their mental health outcomes in adulthood.

A child being exposed to interparental violence is a form of maltreatment with consequences for a child’s development, but in some countries it is only seen as a risk factor for later problems with no specific outcomes.

The authors studied 3,023 adults in the Paris metropolitan area in 2005 by carrying out at-home face to face interviews.

People who agreed to take part were found from a population based cohort study in Paris held by the National Institute of Health and Medical Research.

The researchers measured current depression and lifetime suicide attempts, intimate partner violence, violence against children and alcohol dependence.

They also asked people about childhood adversities such as parental separation, divorce, parental death or imprisonment, alcoholism and physical and/or sexual abuse, as well as asking about social level stressors including poor parental health, housing problems, prolonged parental unemployment, and financial troubles.

Among the group of people interviewed, 16percent said they had witnessed interparental violence before the age of 18 and this was far more common in certain situations.

Other factors were also relevant and witnessing violence was more common in families with financial problems, serious parental diseases, housing problems or unemployment.

After adjusting for family and social level stressors, the researchers found that people who were exposed to interparental violence had a 1.4 times higher risk of having depression, were more than three times more likely to be involved in conjugal violence, were almost five times more likely to mistreat their own child and 1.75 times more likely to have a dependence on alcohol.

The authors concluded: “Intensification of prevention of and screening for domestic violence including interparental violence is a public health issue for the well-being of future generations.” (ANI)

Govt. to act ruthlessly against malpractices in defence contracts: Antony

New Delhi, May 27 (ANI): In the toughest ever message yet to be issued by a Defence Minister to stem corruption in armed forces procurements, A K Antony today said the Government “would not hesitate to ruthlessly cancel contracts,” if malpractices are found in any acquisition.

Antony asked organisations such as the CII and the FICCI, etc to help the government to maintain transparency and integrity in defence contracts, and added that the government would not tolerate “wheeling dealing or corruption.”

“We are determined that we need procurements, (but) we cannot compromise on transparency. At times, we have found certain manipulations, malpractices; we cannot ignore that so we ruthlessly cancelled certain major ticket items.”

“In the future also if there are any malpractices we will not be lenient, we will take the harsh lane,” Antony further said.

The government cancelled at least two defence deals during Antony’s previous tenure as Defence Minister, including the Eurocopter light utility helicopter deal owing to some malpractices.

Signifying the government’s assurance in rooting out corruption and to give a strong warning to private contractors, Antony added, ” They should not try to bribe our people. We will not be lenient. We will take strong action.”

The Defence Minister was speaking at Defcom India 2009 seminar themed on “Informatics for Defence Transformation and Technology Development in the Information Age”.

The seminar saw participation of over 400 delegates and 100 plus companies.

Antony said the Government has consciously taken a decision to minimise the country’s dependence on import of defence systems and platforms, and agreed that more products should be sourced on the basis of “buy and make” rather than ‘buy’ category alone.

He lamented that nearly 70 percent of defence weapons and systems are still being imported and only 30 percent are being indigenously produced.

Antony said the turbulence in our immediate neighbourhood puts the political stability in our country in an even better perspective.

He said the need to modernise our defence forces to preserve our territorial integrity in the face of asymmetric and unconventional means of warfare couldn’t be overemphasised.

Antony called for a synergy of efforts of the armed forces, the industry, the academia and research and development establishments to transform our defence forces to a network centric force.

The transformation of defence forces is a continuous process, and the overall aim should be to bring about sustained competitive advantages in warfare, Antony said.

Referring to the new challenges before the Armed Forces, both in terms of the concepts involved and the material needed, Antony said it is neither possible nor feasible to have equipment and systems on stand-by for all conceivable variants of modern military conflicts. By Praful Kumar Singh (ANI)

Agra faces acute drinking water shortage

Agra, May 18 (ANI): Ever since the mercury has risen this summer, breaking several oldecords, residents of Agra are enduring acute shortage of drinking water and even compelled to buy water at a premium.

In some areas one can witness the broken water mains over a drain and people hanging their buckets to fetch drinking water from the cracked pipes just above the slushy drain.

Water from pipes next to drains has also led to cases of water-borne diseases, particularly among the children.

There are also certain neighbourhoods where the womenfolk have to walk as much as two to three kilometres to fetch water. They manage to gather water by digging and it is not fit for drinking.

“There are no hand pumps. There is no water in taps as well. Women have to travel long distances to get water. We are facing a lot of problems. Children are falling sick. There is no water anywhere somehow we are getting water from cracked pipes near drains and are trying to fulfill our requirement,’ said Hem Lata, a resident.

Capitalising on the scarcity of water, many unscrupulous elements, who own tankers are selling water. However, dependence of water tankers is not a permanent solution for people as often these tankers do not arrive on time.

“These people get tankers here and sell water. Sometimes we get it at one or two rupees per bucket or ten to fifteen rupees per drum, this is the way everybody here gets water,” said Bashir Ahmed, another resident.

Jawahar Ram, General Manager of Agra Water Board said that in summer season water crisis is felt by the people and the demand is more as such extra measures are taken to bridge the gap.

“As compared to winters there is more requirement of water in summers and thus people start feeling crisis. So I continuously make appeal to people that they should use water wisely. They should drink it and close the tap so that water is not wasted. And wherever people are facing problems I have opened a Control Room here so that their problems are immediately answered,” he added.

Water crisis is not a new phenomenon in India. Many parts of the country experience water shortage. (ANI)