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Research and Markets: Asthma: Clinician’s Desk Reference: Asthma Now Effects Around 7.2% of the World’s Population

June 5, 2010 By vani Leave a Comment

DUBLIN–(Business Wire)–
Research and Markets
(http://www.researchandmarkets.com/research/ddd8fd/asthma_clinician) has
announced the addition of the “Asthma: Clinician’s Desk Reference” book to their
offering.

As the series title implies each Clinicians Desk Reference will be a practical
resource and a daily aid for physicians in the hospital setting and in primary
care.

Asthma is one of the most important chronic disorders in the developed world.
Evidence from around the world shows the prevalence of asthma has increased
considerably since 1975, and now affects around 7.2% of the world population
(about 100 million individuals). In the UK asthma is now the most common chronic
disease affecting all age groups with approximately 11% of the population being
diagnosed as having asthma at some time in their lives.

Understanding of the basic mechanisms involved in the pathogenesis of asthma has
improved dramatically over the past 20 years. Along with this increase in basic
scientific knowledge, randomised clinical trials have produced evidence to guide
clinicians in how to manage patients with asthma.

The book covers epidemiology, diagnosis and management, and takes a look at
future developments. The authors highlight the under diagnosis of occupational
asthma and emphasise the importance of effective patient education, particularly
asthma action plans. There are ten clinical cases dealing with common diagnostic
and management problems, frequently asked questions and appendices containing
resources for patients and clinicians including useful websites, information
leaflets and major references.

Key features:

* Covers epidemiology, diagnosis, and management of asthma in children and
adults
* Focus on occupational asthma
* Chapter on asthma in primary care
* Clinical cases
* Resources for doctor and patient, plus frequently asked questions

Key Topics Covered:

1. The size of the problem

2. Scientific principles of asthma

3. Making a diagnosis of asthma

4. Inhaler devices

5. Long term management of asthma in adults

6. Management of acute asthma in adults

7. Management of childhood asthma

8. Occupational asthma

9. Educating patients and clinicians

10. Asthma in primary care

11. The future

12. Clinical cases

13. Frequently asked questions by patients

Practice points

Index

For more information visit

http://www.researchandmarkets.com/research/ddd8fd/asthma_clinician

Research and Markets
Laura Wood, Senior Manager
press@researchandmarkets.com
U.S. Fax: 646-607-1907
Fax (outside U.S.): +353-1-481-1716

Filed Under: International News Tagged With: age groups, Appendices, asthma, Asthma Children, Asthma In Children, Chronic Disease, Chronic Disorders, clinician, Desk Reference, Information Leaflets, Management Of Asthma, Management Problems, Occupational Asthma, Pathogenesis Of Asthma, Patient Education, prevalence of asthma, Primary Care, Reference Book, scientific knowledge, world population

‘Obesity crisis on our hands’

April 10, 2010 By vani Leave a Comment

New research has found that obesity has overtaken tobacco as the leading preventable cause of disease in Western Australia.

The WA Health Department study compared the impact several risk factors had on the level of disease in 2006.

It found that obesity was responsible for 8.7 per cent of diseases that year, with tobacco contributing to 6.5 per cent.

The Department’s Veronica Hoad says smoking has previously been the largest risk factor.

“The amount of people smoking tobacco has continously declined over time, whereas the amount of people becoming more overweight and obese has increased over time, and that has resulted in more disease being caused by being overweight and obese.”

Ms Hoad says the findings are significant.

“The reason why the burden attributed to smoking has decreased is because of successful public health efforts.

“Now, if we do not stop people getting overweight and obese then we’re going to have a real problem. There’s going to be more chronic disease and death.”

Action needed

The Public Health Association of Australia president, Mike Daube, says the results are worrying and can be applied nationally.

“It’s telling us that we do have an obesity crisis on our hands.

“Trends in WA are going to be very similar to trends across the country.

“What it’s telling us is that obesity now is one of the biggest threats we face to our public health.”

Mike Daube says the findings should send a strong message that urgent action needs to be taken to tackle obesity.

“There’s responsibility for all of us, as individuals, as parents, as community members and for governments.

“They have to set the lead, they have to introduce comprehensive programs that we can all work along with.”

Serious

The Federal Health Minister Nicola Roxon has acknowkedged that obesity is a serious and growing problem in Australia.

Ms Roxon says the Federal Government has already studied the risk factors and is acting to prevent people from becoming obese.

“We’re tackling this on lots of different fronts – what’s the message to the general public, what can we do to help parents and families in giving their children healthy choices and healthy lifestyles.

“What should we do at the government level, what can our health professionals do.

“But, I think it’s a very serious growing problem that we need to keep a close eye on and invest in these areas.”

Filed Under: International News Tagged With: being overweight, Chronic Disease, Community Members, Daube, federal government, Federal Health Minister, Health, Hoad, Leading Preventable Cause, nicola roxon, obesity, obesity crisis, perth, president mike, Public Health Association, Public Health Association Of Australia, public health efforts, risk factor, risk factors, Urgent Action, Veronica, wa, Wa Health Department, Western Australia

Experts focus on Indigenous health

April 8, 2010 By vani Leave a Comment

Chronic diseases in Indigenous communities will be analysed over the next few months in two Rural Health Education Foundation (RHEF) initiatives.

The RHEF will host an interactive satellite conference later this month with a panel of Indigenous health specialists from Queensland and the Northern Territory.

RHEF executive officer Don Perlgut says highlights of the program will then be edited into a package to support remote community health education.

“This focus on chronic disease is really about prevention and making sure that Aboriginal people and Torres Strait Islander people in Australia are able to maintain health,” he said.

Filed Under: International News Tagged With: Aboriginal People, Chronic Disease, chronic diseases, Community Education, Community Health Education, executive officer, Health Diseases, Health Specialists, Indigenous Communities, initiatives, Interactive Satellite, Northern Territory, Officer Don, prevention, Queensland, Rural Health Education, Rural Health Education Foundation, Satellite Conference, torres strait islander, Torres Strait Islander People

Minister lauds health service

March 31, 2010 By vani Leave a Comment

Federal Rural Health Minister Warren Snowdon has visited far west New South Wales and met health and community stakeholders.

Mr Snowdon met with staff from the Maari Ma Health Service and the Wilcannia Health Service and toured the Broken Hill Hospital and the University Department of Rural Health.

He says it is pleasing to see Maari Ma is providing health care not only to Indigenous people but the whole community.

“To see that relationship and to see that they’re able to manage their chronic disease priorities … in Aboriginal communities, while at the same time servicing the rest of the community is a very good example of what can be done,” Mr Snowdon said.

Filed Under: International News Tagged With: aboriginal communities, broken-hill-2880, Chronic Disease, Community Stakeholders, health care, Health Minister, Health Service, healthcare facilities, indigenous, Indigenous People, Lauds, Maari Ma Health, New South Wales, priorities, relationship, Rural Health, snowdon, wilcannia-2836

Climate change and chronic disease study

March 30, 2010 By vani Leave a Comment

Researchers at the University of Tasmania are calling for volunteers to take part in a study into the effects of climate change on people suffering from chronic diseases.

The study will look at how people with conditions such as type 2 diabetes and heart disease cope with extreme changes in temperature.

Sibella King from the University’s School of Human Life Science says if a person’s heart is already weakened from disease, it may have to work harder due to rising global temperatures.

“In the heat we expect people’s blood pressure to fall a little bit, and when that happens the heart rate will rise to compensate for the falling pressure,” she said.

“So you get a higher heart rate and a lower blood pressure, so that’s what we would expect to see.”

Filed Under: International News Tagged With: Chronic Disease, chronic diseases, climate change, diabetes, diabetes and heart disease, diseases-and-disorders, effects of climate change, Extreme Changes, global temperatures, heart disease, heart rate, hobart-7000, Human Life Science, launceston-7250, little bit, lower blood pressure, medical research, people, study researchers, TAS, type 2 diabetes, Type Diabetes, university of tasmania, volunteers

Forum focuses on pain management

March 27, 2010 By vani Leave a Comment

A support group for people with chronic pain says there is just one pain specialist between the Tweed and Brisbane rivers.

The Australian Pain Management Association and the Chronic Pain Association are hosting a community forum on the issue on the Gold Coast on Sunday.

A spokeswoman says more than 100 people are expected to listen to medical professionals and share their experiences at the Gold Coast Entertainment Centre on Sunday.

An authority on pain says it is often a neglected area of medicine.

The director of pain centres at two Melbourne Hospitals, Dr Jane Trinca, says acute pain can become a debilitating, chronic disease.

She says Australia needs more pain specialists and more general practitioners with a deeper understanding of the issue.

“It’s been treated a little bit like a second class citizen by some people or by some systems and it is true that doctors are incredibly busy these days because there aren’t as many doctors to patients as there were in the good old days,” she said.

“The doctors certainly do have to prioritise and sometimes the pain aspect does get neglected.”

Doctors, nurses, physiotherapists, occupational therapists and psychologists from throughout Australia will attend the meeting.

Filed Under: International News Tagged With: Acute Pain, broadbeach-4218, Chronic Disease, Chronic Pain Association, Coast Entertainment, Community Forum, deeper understanding, doctors-and-medical-professionals, dr jane, General Practitioners, gold coast, Health, Health Administration, management association, medical professionals, occupational therapists, pain, pain management, Pain Specialist, Pain Specialists, psychologists, Second Class Citizen, spokeswoman, Trinca, tweed

Stomach wraps more effective approach to treat severe acid reflux

March 17, 2010 By vani Leave a Comment

Washington, Mar 17 (ANI): For treatment of severe acid reflux, stomach wrap operations could be a more effective option than acid suppression tablets, according to a new Cochrane Systematic Review.

The study shows a more pronounced improvement in symptoms shortly after surgery than with drug treatment.

Gastro-oesophageal reflux disease (GORD) is a common chronic disease in which acid reflux causes heartburn, acid regurgitation, vomiting and difficulty swallowing.

GORD can be treated by changes to diet and acid suppression tablets, but in the most severe cases, doctors go for a surgical operation called a fundoplication, which involves wrapping part of the stomach around the lower part of the gullet.

However, it is not certain whether this procedure is more effective than medication.

The authors reviewed data from four trials, which together involved 1232 participants.

And their conclusions relate to findings from follow-up up to one year after treatment.

They found that fundoplication operations performed by keyhole surgery were more effective at reducing the symptoms of GORD over this timescale, but that there was little data available to indicate potential benefits over longer timescales.

“There is evidence to suggest that, at least in the short to medium term, surgery is more effective than tablets for treatment of GORD. But surgery does carry a risk and whether this is outweighed by the benefits in the long term is still not certain,” said lead researcher Samantha Wileman of the Health Services Research Unit at the University of Aberdeen in the UK.

“Previous research, prior to the development of keyhole surgery for GORD, has suggested that the benefits of surgery for GORD are not sustained over time, highlighting the importance for future keyhole fundoplication studies to include longer term follow-up. We also need to know more about the clinical and cost implications of long term medication versus surgery,” said Wileman. (ANI)

Filed Under: International News Tagged With: Acid Reflux, Acid Regurgitation, Acid Stomach, Chronic Disease, Cochrane, conclusions, Fundoplication, Gastro Oesophageal Reflux Disease, gullet, health services research, keyhole surgery, Oesophageal Reflux Disease, previous research, researcher, suppression, Term Medication, timescale, university of aberdeen, vomiting, Wileman

Stomach wraps more effective approach to treat severe acid reflux

March 17, 2010 By vani Leave a Comment

Washington, Mar 17 (ANI): For treatment of severe acid reflux, stomach wrap operations could be a more effective option than acid suppression tablets, according to a new Cochrane Systematic Review.

The study shows a more pronounced improvement in symptoms shortly after surgery than with drug treatment.

Gastro-oesophageal reflux disease (GORD) is a common chronic disease in which acid reflux causes heartburn, acid regurgitation, vomiting and difficulty swallowing.

However, it is not certain whether this procedure is more effective than medication.

The authors reviewed data from four trials, which together involved 1232 participants.

And their conclusions relate to findings from follow-up up to one year after treatment.

Regulation of ‘short stature’ gene crucial for growth in kids

August 26, 2009 By admin Leave a Comment

Washington, August 26 (ANI): A team of researchers in Germany have found that not only a gene called SHOX is involved in the development of short stature, but sequences of genetic material on the X and Y chromosome that regulate it are also crucial for growth in children.

Professor Gudrun Rappold, the Director of the Department of Human Molecular Genetics at Heidelberg University Hospital, points out that these gene regulators determine how frequently a gene is copied, and, thus, how effective it is.

In many cases, she says, the mutation of one regulatory sequence of the SHOX gene is sufficient to give rise to the full-blown syndrome.

Publishing their results in the Journal of Medical Genetics, she and her colleagues have said that their findings may open up new possibilities for diagnosing the cause of short stature, and initiating treatment before it is too late.

According to background information in the report, the SHOX gene (short stature homeobox gene) is responsible for the normal growth of bones, and is often mutated in short-stature patients-no more than 160 cm of final height in men, and 150 cm in women.

Hormone disorders, malnutrition, chronic disease, or a genetic disorder are some of the causes of short stature. If, in addition to short stature, other symptoms such as short forearms and lower legs or other bone malformations also occur, it is considered a syndrome.

However, often no exact cause can be determined and other typical features are lacking – this is then known as idiopathic short stature.

In 2007, a research team led by Professor Rappold found that in over 4 percent of children with idiopathic short stature, the trigger for the disorder was a mutation in the SHOX gene. er latest study has shown that not only the gene itself, but its regulators as well can be crucial for developing the disease.

During the study, the researchers examined the genetic material from a total of 893 subjects.

About 5 percent of the patients with idiopathic short stature, and 80 percent of the patients with Leri-Weill syndrome, had mutations in the segment either including or around the SHOX gene.

The researchers said that some patients had an intact SHOX gene, but an unexpectedly high number of mutations in its enhancer sequences: for 26 percent of patients with SHOX deficiency and idiopathic short stature and for 45 percent of patients with SHOX deficiency and Leri-Weill syndrome, the disease could be attributed solely to a genetic mutation of the enhancer sequence.

“The astounding thing is that this enhancer mutation is quite far away from the affected gene and yet it still leads to the exact same clinical symptoms as a mutation in the gene itself,” said Professor Rappold.

The researchers hope that their results will give them a better understanding of the causes of the disease, and allow them to optimise the diagnostic possibilities for patients with SHOX gene mutations.

“Patients who suffer from their short stature often have a great need to be able to name the cause. Even if it is not possible to treat the cause, patients with mutations of the SHOX gene can benefit from a treatment of the symptoms with growth hormones,” said Professor Rappold. (ANI)

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Can an individual’s bitter-taste sensitivity help determine diabetes risk?

July 11, 2009 By admin Leave a Comment

Washington, July 11 (ANI): A research team at Kansas State University, including an Indian origin scientist, are studying whether an individual’s bitterness sensitivity can help predict his/her risk of developing type 2 diabetes.

Lead researcher Kathy Nguyen, senior in public health nutrition along with colleagues Koushik Adhikari and Mark Haub, are studying the genotypes of diabetic and non-diabetic individuals to determine the possible link.

For the study, Nguyen is collecting cheek cell samples from about 60 men and women between the ages of 40 and 70. The sample includes people with and without type 2 diabetes.

The researchers will later genotype two variations within a DNA sequence to determine whether the individuals are supertasters, tasters or non-tasters of bitterness.

Supertasters are more sensitive to bitterness than tasters, and non-tasters are not sensitive.

The team hopes that by understanding whether bitterness sensitivity is linked to type 2 diabetes, there is a potential to screen individuals for bitterness sensitivity, and to use that information as a predictive marker for the disease and other chronic disease such as heart disease and obesity.

“This is a preliminary stage with a small sample size,” Adhikari said.

“The study has to be repeated with a larger population of different ethnicities to arrive at any meaningful conclusions. However, Kathy will establish the protocol for this project,” he added. (ANI)

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Unfit young adults may develop diabetes in middle age

June 23, 2009 By admin Leave a Comment

WASHINGTON: Men and women between 18 and 30 years with low aerobic fitness levels are more likely to develop diabetes in 20 years, a study said.

Study lead author Mercedes Carnethon from Northwestern University said: “These young adults are setting the stage for chronic disease in middle age by not being physically active and fit.”

“People who have low fitness in their late teens and 20′s tend to stay the same later in life or even get worse. Not many climb out of that category,” Carnethon added.

In the study, Body Mass Index (BMI), a measure of the body’s fat content was the most important predictor of who would develop diabetes. Results of the study were measured using a treadmill test.

Carnethon said: “Research shows that combining regular physical activity with a carefully balanced diet can help most people maintain a healthy body weight and lower the likelihood of developing diabetes.”

Filed Under: Health News Tagged With: Aerobic Fitness, balanced diet, body mass index, body mass index bmi, Chronic Disease, diabetes, diabetes results, fat content, fitness levels, Healthy Body Weight, likelihood, men and women, Mercedes, middle-age, Northwestern University, regular physical activity, teens, Treadmill Test, Washington Men, young adults

Aerobically unfit young adults likely to develop diabetes in middle age

June 19, 2009 By admin Leave a Comment

Washington, June 19 : Young adults who have low aerobic fitness levels are two to three times more likely to develop diabetes in middle age, finds a new study.

“These young adults are setting the stage for chronic disease in middle age by not being physically active and fit,” said Mercedes Carnethon, lead author and assistant professor of preventive medicine at Northwestern”s Feinberg School.

“People who have low fitness in their late teens and 20”s tend to stay the same later in life or even get worse. Not many climb out of that category,” Carnethon added.

The study focussed on the relationship between aerobic fitness, measured by treadmill test and development of diabetes.

Carnethon insists that unfit young adults can avoid a future with diabetes by exercising and losing weight.

“Improving your fitness through physical activity is one way you can modify your body fat,” she said.

“Research shows that combining regular physical activity with a carefully balanced diet can help most people maintain a healthy body weight and lower the likelihood of developing diabetes,” she added.

The study appears in journal Diabetes Care.

Filed Under: Health News Tagged With: Aerobic Fitness, array, assistant professor, balanced diet, body fat, Chronic Disease, diabetes, diabetes care, Feinberg School, fitness levels, journal diabetes, likelihood, losing weight, Mercedes, middle-age, preventive medicine, regular physical activity, relationship, three times, Treadmill Test, young adults

Cancer wouldn’t be deadly in the next 20 years, say UK expert

May 15, 2009 By admin Leave a Comment

London, May 15 (ANI): While the rate of cancer survival has been improving day-by-day, a British expert reckons that cancer will no longer be a killer in the next 20 years.

Karol Sikora, professor of Cancer Medicine at Imperial College London, has said that the treatments for the disease are undergoing a “revolution”, which means that within just two decades, “we will simply run out of things from which to die.”

And rather than facing a possible death sentence, cancer patients will be treated as if they have a long-term illness like diabetes, heart disease or asthma.

Sikora said that better technologies, better delivery systems to treat the disease, and financial constraints are expected in the near future.

And as improved cancer care leads to better survival rates, higher prevalence of the disease in our populations will lead to greater societal pressures as people will be expecting much more from medicine.

“Within 20 years cancer will be a chronic disease, joining conditions such as diabetes, heart disease and asthma,” the Daily Express quoted Sikora as saying.

“These conditions impact on the way people live and do not inexorably lead to death.

“The model of prostate cancer, where many men die with it rather than from it, will be common for most cancers.

“Even greater progress will be made in understanding myriad causes of cancer,” Silora added.

A report authored by Sikora appears on scripnews.com, published by Informa Pharma. (ANI)

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Smoking, high BP, obesity: Leading causes of death in US

May 2, 2009 By admin Leave a Comment

Washington, Apr 28 (ANI): Smoking, high blood pressure and being overweight-these are the top three preventable risk factors for premature mortality in the United States, according to a new study.

Led by researchers at the Harvard School of Public Health (HSPH), the collaborative study found that smoking is responsible for 467,000 premature deaths each year, high blood pressure for 395,000, and being overweight for 216,000.

The effects of smoking work out to be about one in five deaths in American adults, while high blood pressure is responsible for one in six deaths.

The study is the most comprehensive analysis till date, which looked at how diet, lifestyle and metabolic risk factors for chronic disease contribute to mortality in the U.S.

“The large magnitude of the numbers for many of these risks made us pause. To have hundreds of thousands of premature deaths caused by these modifiable risk factors is shocking and should motivate a serious look at whether our public health system has sufficient capacity to implement interventions and whether it is currently focusing on the right set of interventions,” said Goodarz Danaei, a doctoral student at HSPH and the lead author of the study.
Also, the researchers found large effects from a series of other preventable dietary and lifestyle risk factors.

All of the deaths calculated in the study were considered premature or preventable in that the victims would not have died when they did if they had not been subject to the behaviours or activities linked to their deaths.

All the risk factors are modifiable through a range of public health and health system interventions.

This is also the first to use methods that allowed a true comparison of a diverse set of risks in terms of how many deaths each of the risk factors is responsible for.

The researchers analysed data from a number of public sources, including from the National Center for Health Statistics and numerous published epidemiological studies and clinical trials.

“The findings should be a reminder that although we have been effective in partially reducing smoking and high blood pressure, we have not yet completed the task and have a great deal more to do on these major preventable factors,” said senior author Majid Ezzati.

The study appears in the latest edition of the open-access journal PLoS Medicine. (ANI)

Filed Under: Health News Tagged With: american adults, behaviours, Causes Of Death, Chronic Disease, collaborative study, doctoral student, effects of smoking, epidemiological studies, harvard school of public health, high blood pressure, Leading Causes Of Death, lifestyle risk factors, metabolic risk factors, Modifiable Risk Factors, National Center For Health Statistics, premature deaths, premature mortality, preventable, public health system, public sources, school of public health, true comparison

Breastfeeding cuts mums’ heart attack, stroke risk

April 21, 2009 By admin Leave a Comment

Washington, April 21 (ANI): It is known that breastfeeding is important for babies’ health. But now, a new study has shown that nursing is equally vital for mothers’ health.

University of Pittsburgh researchers said that the longer women breastfeed, the lower their risk of heart attacks, strokes and cardiovascular disease.

“Heart disease is the leading cause of death for women, so it’s vitally important for us to know what we can do to protect ourselves. We have known for years that breastfeeding is important for babies’ health; we now know that it is important for mothers’ health as well,” said Eleanor Bimla Schwarz, M.D., M.S., assistant professor of medicine, epidemiology, and obstetrics, gynaecology and reproductive sciences at the University of Pittsburgh.

According to the study, postmenopausal women who breastfed for at least one month had lower rates of diabetes, high blood pressure and high cholesterol, all known to cause heart disease.

Women who had breastfed their babies for more than a year were 10 percent less likely to have had a heart attack, stroke, or developed heart disease than women who had never breastfed.

Dr. Schwarz and colleagues found that the benefits from breastfeeding were long-term ? an average of 35 years had passed since women enrolled in the study had last breastfed an infant.

“The longer a mother nurses her baby, the better for both of them. Our study provides another good reason for workplace policies to encourage women to breastfeed their infants,” Schwarz said.

The findings are based on 139,681 postmenopausal women enrolled in the Women’s Health Initiative study of chronic disease, initiated in 1994.

The study is published in the May issue of Obstetrics and Gynaecology. (ANI)

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Research and Markets: Asthma: Clinician’s Desk Reference: Asthma Now Effects Around 7.2% of the World’s Population

‘Obesity crisis on our hands’

Experts focus on Indigenous health

Minister lauds health service

Climate change and chronic disease study

Forum focuses on pain management

Stomach wraps more effective approach to treat severe acid reflux

Stomach wraps more effective approach to treat severe acid reflux

Regulation of ‘short stature’ gene crucial for growth in kids

Can an individual’s bitter-taste sensitivity help determine diabetes risk?

Unfit young adults may develop diabetes in middle age

Aerobically unfit young adults likely to develop diabetes in middle age

Cancer wouldn’t be deadly in the next 20 years, say UK expert

Smoking, high BP, obesity: Leading causes of death in US

Breastfeeding cuts mums’ heart attack, stroke risk

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