Traffic police in central Victoria say they are frustrated that motorists are not heeding road safety messages.

The comments come after two serious car crashes in the region on Wednesday.

Sergeant Geoff Neil says some drivers do not believe they will ever be involved in an accident.

“We have an element in our community that don’t think, don’t care,” he said.

A 51-year-old Kyneton woman was killed when her car overturned on the Calder Freeway at Macedon on Wednesday afternoon.

Shortly afterwards, four boys were injured in a separate accident when their car hit a tree in New Gisborne.

Police say it appears the driver of the second car was an unlicensed 16-year-old. Investigations are continuing and no charges have been laid.