‘HPV testing should be the primary screening method for cervical cancer’

London, April 28 (ANI): Scientists at Queen Mary, University of London, say that cervical cancer screening intervals could be extended to five years for women aged 30 and over if the primary screening method was human papillomavirus (HPV) testing.

A study showed that HPV tests are very accurate in identifying early signs of cervical cancer, detecting more serious abnormalities compared to current cytology screening in women aged 30 and over.

The study, led by David Mesher, from the Cancer Research UK Centre for Epidemiology, Mathematics and Statistics at Queen Mary, University of London, recruited more than 11,000 women from 161 family practices around the UK.

Two samples were taken from each of the women; one using the conventional cytology screening method and the other was sent for HPV testing.

The researchers found that women with HPV negative results had a lower rate of developing pre-cancerous cells for at least six years compared with women who recorded a negative cytology result.

The research has been published in the British Journal of Cancer. (ANI)

Second child within a year ‘increases breast cancer risk’

London, Sept 14 (ANI): Having a second child within a year of the first birth can increase a woman’s risk of developing breast cancer, finds a new study.

The research, involving 30,000 women each of whom had produced five or more children, has shown that those with a gap of less than 12 month were 5.2 times more likely to develop the advanced ductal breast cancer than women who had a gap of three or more years.

Although it is unclear that why the risk increases, researchers believe hormones might be involved.

Alternatively, other risk factors may have influenced the results, including being overweight, and whether or not the mother chooses to breast-feed.

“Women who had their first two births close together should not be worried by these findings because the study’s results are not conclusive,” the Telegraph quoted Josephine Querido, senior science information officer at Cancer Research UK, as saying.

“The researchers looked at a very specific group of women – those who had a specific type of breast cancer, who had advanced tumours, who were under 50, and who had at least five children. In studies like this, dividing the group of people you’re looking at into lots of smaller groups makes it likely that you’ll find a positive result in one of the subgroups just by chance.

“For all women, it’s important to go to the GP if they spot any unusual changes in their breast, and to go for screening when invited,” Querido added.

The study appears in the British Journal of Cancer. (ANI)

Vegetarians develop ‘fewer’ cancers

London, July 1 (ANI): Vegetarians may be less likely than meat eaters to develop cancers of the blood, bladder and stomach, suggests a study.

Lead researcher Professor Tim Key, however, insists that this may not be the case for all forms of the disease.

Scientists from universities in the UK and New Zealand examined 61,566 British men and women, including meat-eaters, those who ate fish but not meat, and those who did not ate either.

The researchers found that while nearly 33 people in 100 in the general population would develop cancer during their lifetime, for those who abstained from meat the risk was reduced to about 29 in 100.

The study discovered considerable differences between meat-eaters and vegetarians in the propensity to cancers of the lymph and the blood, with the latter just over half as likely to develop these forms of the disease.

Vegetarians were observed to get notably fewer of stomach, bladder, non-Hodgkin’s lymphoma and multiple myeloma cancers.

But Key warned that the findings, published in the British Journal of Cancer, were not strong enough to draw absolute conclusions.

“At the moment these findings are not strong enough to ask for particularly large changes in the diets of people following an average balanced diet,” the BBC quoted Key as saying.

A spokesperson for Cancer Research UK, which funded the research, added: “These interesting results add to the evidence that what we eat affects our chances of developing cancer. We know that eating a lot of red and processed meat increases the risk of stomach cancer.

But the links between diet and cancer risk are complex and more research is needed to see how big a part diet plays and which specific dietary factors are most important.”

Myeloma UK also said: “Dietary advice to myeloma patients remains aligned with national guidance – that they should eat a healthy, balanced diet high in fibre, fruit and vegetables and low in saturated fat, salt and red and processed meat.”

Dr Panagiota Mitrou, Science and Research Programme Manager for the World Cancer Research Fund, further said: “The suggestion that vegetarians might be at reduced risk of blood cancers is particularly interesting. However, this finding should be treated with caution since not much is known about the link between diet and these types of cancer. Further studies of vegetarians are needed before we can be confident this is actually the case.” (ANI)

Family history raises breast cancer risk even without faulty gene

London, Jan 20 (ANI): Women with a family history of breast cancer are four times more likely to develop breast cancer than other women – even if they don’t have high-risk genes, according to a new study.

For the study, scientists looked for the first time at the risk of getting the disease for women who do not have a faulty gene but have family members who have developed breast cancer.

About one in six women with breast cancer have a family history of the disease, which means about 13 per cent of all sufferers have a strong family record of it, but do not have a faulty gene.

The researchers looked at women who had one first- degree relative – mother, daughter or sister – under the age of 50 with breast cancer and at least one other relative like a cousin or aunt with breast cancer, or three relatives of any age with the disease.

They found that although the risk of breast cancer in the general population was one in nine, for the group studied the risk rose to more than one in three.
According to the researchers, a significant family history of breast cancer alone could be strong enough grounds for doctors to offer preventative treatments.

“This is the first time the breast cancer risk for this group of women has been measured, and it’s significantly higher than that of the general population,” the Daily Express quoted lead author Dr Steven Narod, of Toronto University in Canada, as saying.

“It’s important to start thinking about action to prevent breast cancer in women at high risk of developing the disease,” he added.

The study is published in the British Journal of Cancer. (ANI)