Energy drinks start their kick as soon as they touch your tongue

London, Apr 30 (ANI): Energy drinks starting their “kick work” as soon as they touch your tongue, concludes a new study.

In the study, Nicholas Gant at the University of Auckland in New Zealand and team had 16 participants tire out their biceps by flexing them for 11 minutes before rinsing their mouths with either a carbohydrate drink or a non-calorific, taste-matched one.

“One second after rinsing, the team applied transcranial magnetic stimulation to the participants” scalps, which aided the detection of activity in the motor cortex, a brain area known to send signals to biceps.

“The team found that the volunteers who swilled with carbohydrates were able to flex with more force immediately afterwards, and had a 30 per cent stronger neural response compared with those given placebo,” reports New Scientist.

The study has been published in Brain Research. (ANI)

How the brain constructs morality

Washington, Mar 25 (ANI): Our ability to respond appropriately to intended harms � that is, with outrage toward the perpetrator � is seated in a brain region associated with regulating emotions, says a new study.

According to MIT neuroscientists, patients with damage to this brain area, known as the ventromedial prefrontal cortex (VMPC), are unable to conjure a normal emotional response to hypothetical situations in which a person tries, but fails, to kill another person. Therefore, they judge the situation based only on the outcome, and do not hold the attempted murderer morally responsible.

The finding offers a new piece to the puzzle of how the human brain constructs morality, says Liane Young, a postdoctoral associate in MIT”s Department of Brain and Cognitive Sciences and lead author of a paper describing the findings in the March 25 issue of the journal Neuron.

“We”re slowly chipping away at the structure of morality,” says Young. “We”re not the first to show that emotions matter for morality, but this is a more precise look at how emotions matter.”

Working with researchers at the University of Southern California, led by Antonio Damasio, Young studied a group of nine patients with damage (caused by aneurisms or tumors) to the VMPC, a plum-sized area located behind and above the eyes.

Such patients have difficulty processing social emotions such as empathy or embarrassment, but “they have a perfectly intact capacity for reasoning and other cognitive functions,” says Young.

The researchers gave the subjects a series of 24 hypothetical scenarios and asked for their reactions. The scenarios of most interest to the researchers were ones featuring a mismatch between the person”s intention and the outcome � either failed attempts to harm or accidental harms.

When confronted with failed attempts to harm, the patients had no problems understanding the perpetrator”s intentions, but they failed to hold them morally responsible. The patients even judged attempted harms as more permissible than accidental harms (such as accidentally poisoning someone) � a reversal of the pattern seen in normal adults.

“They can process what people are thinking and their intentions, but they just don”t respond emotionally to that information,” says Young. “They can read about a murder attempt and judge it as morally permissible because no harm was done.”

This supports the idea that making moral judgments requires at least two processes � a logical assessment of the intention, and an emotional reaction to it. The study also supports the theory that the emotional component is seated in the VMPC. (ANI)

Why we empathise less with people of other races

London, July 1 (ANI): People often fail to empathise with strangers’ pain, if they belong to a different race than their own, and now a study has revealed what underlies this tendency.

In an imaging study of Chinese and Caucasian people, it was found that the participants’ brains respond less strongly to the pain of strangers whose ethnicity is different when compared with strangers of their own race.

“It’s one of a string of papers that have come out in the cognitive neuroscience literature that helps us to understand some of the unfortunate ways in which racial group identity can influence our reactions to other people,” New Scientist magazine quoted Martha Farah, a cognitive neuroscientist at the University of Pennsylvania in Philadelphia, as saying.

In earlier research, it was shown that the amygdala, a brain area implicated in fear, responds more strongly to pictures of people whose ethnicity is different from the viewer’s, but the responses aren’t uniform.

Other research has shown that activity in other brain areas can dampen the amygdala.

In order to determine how ethnicity also sways the brain’s sense of empathy, Shihui Han and colleagues at Peking University in Beijing conducted their experiments on 17 Chinese and 16 Caucasians volunteers.

All the participants were shown videos of a person being poked in the cheek with a Q-tip cotton bud or a hypodermic syringe, while they had their brains scanned on a functional MRI machine.

The films sparked activity in a region called the anterior cingulate cortex (ACC), which also lights up when people are in pain themselves.

But, for Chinese volunteers, the sight of another Chinese person in pain prompted more of an increase in ACC activity than the pain of a Caucasian person.

Caucasian volunteers from the US, Europe, and Israel also reacted more strongly to sight of another white person in pain.

Farah cautioned that such automatic neural responses did not necessarily translate into behaviour.

“Just because there is this difference in ACC response it doesn’t mean that we are inevitably going to behave less empathically toward the other group,” she added.

As expected, when the volunteers were asked “how painful do you think the model feels?” or “how unpleasant do you feel when observing the video clip?” Chinese and Caucasians volunteers reported that they felt each other’s pain about equally.

The study has been published in the Journal of Neuroscience.(ANI)

Ability to imagine oneself in someone else’s shoes ‘tied to empathy’

Washington, June 24 (ANI): The way our brain handles how we move through space-including being able to imagine literally stepping into someone else’s shoes-may be related to how and why we experience empathy toward others, say researchers.

The new study from Vanderbilt University has been published in the online scientific journal PLoS ONE.

Empathy, partly, involves the ability to simulate the internal states of others.

The authors hypothesized that humans’ ability to manipulate, rotate and simulate mental representations of the physical world, including their own bodies, would contribute significantly to their ability to empathize.

“Our language is full of spatial metaphors, particularly when we attempt to explain or understand how other people think or feel. We often talk about putting ourselves in others’ shoes, seeing something from someone else’s point of view, or figuratively looking over someone’s shoulder,” Sohee Park, report co-author and professor of psychology, said.

“Although future work is needed to elucidate the nature of the relationship between empathy, spatial abilities and their potentially overlapping neural underpinnings, this work provides initial evidence that empathy might be, in part, spatially represented,” the expert said.

“We use spatial manipulations of mental representations all the time as we move through the physical world. As a result, we have readily available cognitive resources to deploy in our attempts to understand what we see. This may extend to our understanding of others’ mental states,” Katharine N. Thakkar, a psychology graduate student at Vanderbilt and the report’s lead author, said.

“Separate lines of neuroimaging research have noted involvement of the same brain area, the parietal cortex, during tasks involving visuo-spatial processes and empathy,” she added.

To test their hypothesis that empathy and spatial processes are linked, the researchers designed an experiment in which subjects had to imagine themselves in the position of another person and make a judgment about where this other person’s arm was pointing. The task required the subject to mentally transform their body position to that of the other person.

“We expected that the efficiency with which people could imagine these transformations would be associated with empathy. Because we were interested in linking spatial ability with empathy, we also included a very simple task of spatial attention called the line bisection task.

This test involves looking at a horizontal line and marking the midpoint. Although this task is very simple, it appears to be a powerful way to assess subtle biases in spatial attention,” Thakkar said.

The researchers compared performance on the test with how empathetic the subjects reported themselves to be. They found that higher self-reported empathy was associated with paying more attention to the right side of space.

Boffins also found that in the female subjects only, the more empathetic people rated themselves, the longer they took to imagine themselves in the position of the person on the screen. (ANI)

Ability to imagine oneself in someone else’s shoes ‘tied to empathy’

Washington, June 24 (ANI): The way our brain handles how we move through space-including being able to imagine literally stepping into someone else’s shoes-may be related to how and why we experience empathy toward others, say researchers.

The new study from Vanderbilt University has been published in the online scientific journal PLoS ONE.

Empathy, partly, involves the ability to simulate the internal states of others.

The authors hypothesized that humans’ ability to manipulate, rotate and simulate mental representations of the physical world, including their own bodies, would contribute significantly to their ability to empathize.

“Our language is full of spatial metaphors, particularly when we attempt to explain or understand how other people think or feel. We often talk about putting ourselves in others’ shoes, seeing something from someone else’s point of view, or figuratively looking over someone’s shoulder,” Sohee Park, report co-author and professor of psychology, said.

“Although future work is needed to elucidate the nature of the relationship between empathy, spatial abilities and their potentially overlapping neural underpinnings, this work provides initial evidence that empathy might be, in part, spatially represented,” the expert said.

“We use spatial manipulations of mental representations all the time as we move through the physical world. As a result, we have readily available cognitive resources to deploy in our attempts to understand what we see. This may extend to our understanding of others’ mental states,” Katharine N. Thakkar, a psychology graduate student at Vanderbilt and the report’s lead author, said.

“Separate lines of neuroimaging research have noted involvement of the same brain area, the parietal cortex, during tasks involving visuo-spatial processes and empathy,” she added.

To test their hypothesis that empathy and spatial processes are linked, the researchers designed an experiment in which subjects had to imagine themselves in the position of another person and make a judgment about where this other person’s arm was pointing. The task required the subject to mentally transform their body position to that of the other person.

“We expected that the efficiency with which people could imagine these transformations would be associated with empathy. Because we were interested in linking spatial ability with empathy, we also included a very simple task of spatial attention called the line bisection task.

This test involves looking at a horizontal line and marking the midpoint. Although this task is very simple, it appears to be a powerful way to assess subtle biases in spatial attention,” Thakkar said.

The researchers compared performance on the test with how empathetic the subjects reported themselves to be. They found that higher self-reported empathy was associated with paying more attention to the right side of space.

Boffins also found that in the female subjects only, the more empathetic people rated themselves, the longer they took to imagine themselves in the position of the person on the screen. (ANI)

Everyone uses different strategies while making risky decisions

Washington, May 28 (ANI): People use different strategies while making difficult economic decisions, according to a brain activation study by neuroscientists at the Duke University Medical Center.

In the study, the researchers used functional magnetic resonance imaging (fMRI) to observe real-time changes in brain function while participants evaluated complex decision-making problems.

“People in our study, like the population at large, differed in the strategies they use to make economic decisions. What sort of strategy people tended to use could be predicted, surprisingly, by how their brain responded to rewards: if there were large responses to monetary reward in a brain area called the ventral striatum, that person tended to simplify decision problems to only consider winning or losing,” said Scott Huettel, senior author of the study.

“Using studies like this to build a better understanding of how our brains represent our decision strategies may someday allow researchers to use someone’s personal traits – say, an adolescent with high impulsivity, but ongoing depression – to predict the decisions that he or she will make.

“This could lead to many real-world benefits: designing more effective interventions or creating more useful educational material,” he added.

In the study, the researchers scanned 23 participants, and observed real-time changes in brain function as they evaluated complex multi-outcome lotteries.

“Our goal was to come up with a risky decision task that would both discriminate between alternative models of choice and represent something that often happens when people allocate scarce resources to make a risky choice more attractive. It was also nice that the task is complex enough to relate to ‘real-world’ decisions but simple enough to be studied using functional MRI,” said Dr. John W. Payne, the Joseph J. Ruvane, Jr. Professor of Business.

And the results revealed that the brain regions classically associated with “rational” processing, particularly the lateral prefrontal cortex, were most active when subjects used a simplifying strategy inconsistent with traditional rational-choice models.

“This result suggests that it was the type of computation that the participants were doing at any given time that activates a brain region, not whether the thought process is rational or irrational,” said lead author Vinod Venkatraman, from the Department of Psychology and Neuroscience at Duke.

“(The finding) argues strongly against the commonly held notion that there are ‘rational’ and ‘irrational’ parts of the brain,’” added Huettel.

The study also showed that the medial prefrontal region of the brain shapes moment-to-moment changes in the strategies people use to make decisions.

“We all make some decisions opposite to our usual tendencies. When we do so, this brain region comes online and alters activation in other choice-related regions,” said Huettel.

The study has been published online in Neuron. (ANI)

Brain area that makes person sociable identified

Washington, May 20 (ANI): Whether someone is a ‘people-person’ may depend on their brain’s structure, say researchers.

The greater the concentration of brain tissue in certain parts of the brain, the more likely they are to be a warm, sentimental person, Cambridge University researchers added.

To reach the conclusion, Maël Lebreton and colleagues from the Cambridge Department of Psychiatry, in collaboration with Oulu University, Finland, examined the relationship between personality and brain structure in 41 male volunteers.

The volunteers underwent a brain scan using Magnetic Resonance Imaging (MRI). They also completed a questionnaire that asked them to rate themselves on items such as ‘I make a warm personal connection with most people’, or ‘I like to please other people as much as I can’. The answers to the questionnaire provide an overall measure of emotional warmth and sociability called social reward dependence.

The researchers then analysed the relationship between social reward dependence and the concentration of grey matter (brain-cell containing tissue) in different brain regions. They found that the greater the concentration of tissue in the orbitofrontal cortex (the outer strip of the brain just above the eyes), and in the ventral striatum (a deep structure in the centre of the brain), the higher they tended to score on the social reward dependence measure.

The research is published in the European Journal of Neuroscience.

Dr Graham Murray, who is funded by the Medical Research Council and who led the research, said: “Sociability and emotional warmth are very complex features of our personality. This research helps us understand at a biological level why people differ in the degrees to which we express those traits.”

But he cautioned, “As this research is only correlational and cross-sectional, it cannot prove that brain structure determines personality. It could even be that your personality, through experience, helps in part to determine your brain structure.” (ANI)

Our brains use distinct spatial signatures to represent the emotions we hear

Washington, May 15 (ANI): Scientists at the University of Geneva in Switzerland have shown that it is possible to figure out whether a person heard words spoken in anger, joy, relief, or sadness by observing the pattern of activity in the brain.

The researchers claim that theirs is the first study to show that emotional information is represented by distinct spatial signatures in the brain that can be generalized across speakers.

“Correct interpretation of emotion in the voice is highly important – especially in a modern environment where visual emotional signals are often not available,” for instance, when people talk on the phone, said Thomas Ethofer of the university.

“We demonstrated that the spatial pattern of activity within the brain area that processes human voices contains information about the expressed emotion,” he added.

The researchers presented those participating in the study with pseudowords spoken in five ways-with anger, sadness, relief, joy, or no emotion-and simultaneously scanned ther brains with functional magnetic resonance imaging (fMRI).

They then analysed the overall spatial pattern of activity in the auditory cortex by using a method called multivariate pattern analysis.

“While conventional methods analyse each point in the brain separately, we looked at the overall pattern. Consider the following analogy: If you have a puzzle consisting of black and white pieces, it is hard to say whether they belong to a picture of a zebra or a checkerboard if you look at each piece in isolation, but it becomes relatively easy if you put the pieces together,” Ethofer said.

According to the researchers, their analysis showed that they could classify each emotion against all other alternatives.

Ethofer insists that the new findings have not only yielded fresh insight into this most critical of social skills, but that they might also help unravel where it goes wrong in those with various psychiatric disorders.

“Comprehension of emotional prosody is crucial for social functioning and compromised in various psychiatric disorders, including deficits for anger and sadness in schizophrenia, fear and surprise in bipolar affective disorder, and surprise in depression,” the researchers wrote.

“Future research might apply a similar approach as ours to clarify whether these deficits are paralleled by activity changes blurring emotions at the level of auditory cortex, or are due to disrupted patterns within frontal regions reflecting biased interpretation of emotional signals,” they added.

The study has been reported in the journal Current Biology. (ANI)

‘Free will’ spot found in brain

London, May 8 (ANI): Researchers in France have identified the place where free will resides.

Lead scientist Angela Sirigu, a neuroscientist at the CNRS Cognitive Neuroscience Centre in Bron, say that the place lies towards the back of the brain called the parietal cortex.

The finding was made when a neurosurgeon electrically jolted this region in patients undergoing surgery, they felt a desire to wiggle their finger, roll their tongue or move a limb.

Stronger electrical pulses convinced patients they had actually performed these movements, although their bodies remained motionless, reports New Scientist.

“What it tells us is there are specific brain regions that are involved in the consciousness of your movement,” says Sirigu.

Sirigu’s team, including neurosurgeon Carmine Mottolese, performed the experiments on seven patients undergoing brain surgery to remove tumours.

In all but one case, the cancers were located far from the parietal cortex and other areas that Mottolese stimulated.

The team’s work points to two brain areas involved in the decision to move a limb and then execute the action.

Sirigu believes that the parietal cortex makes predictions about future movements and sends instructions to another brain area, the premotor cortex, which returns the outcome of the movement to the parietal cortex.

The study has been published in the journal Science. (ANI)

Imaging study reveals brain abnormalities in autistic tots

Washington, May 5 (ANI): Scientists have found that autistic toddlers have an enlarged amygdala, a brain area known to be linked with functions like the processing of faces and emotion.

Researchers at the University of North Carolina at Chapel Hill also say that this brain abnormality appears to be associated with the ability to share attention with others, a fundamental ability thought to predict later social and language function in children with autism.

“Autism is a complex neurodevelopmental disorder likely involving multiple brain systems,” the authors write as background information in the article.

“Converging evidence from magnetic resonance imaging, head circumference and postmortem studies suggests that brain volume enlargement is a characteristic feature of autism, with its onset most likely occurring in the latter part of the first year of life,” write the authors.

Dr. Matthew W. Mosconi conducted a magnetic resonance imaging study involving 50 autistic children and 33 control children.

The children participating in the study underwent brain scans along with testing of certain behavioural features of autism at ages 2 and 4, including a measure of joint attention that involves following another person’s gaze to initiate a shared experience.

The researchers observed that compared to control children, those children with autism were more likely to have amygdala enlargement both at age 2 and age 4.

“These findings suggest that, consistent with a previous report of head circumference growth rates in autism and studies of amygdala volume in childhood, amygdala growth trajectories are accelerated before age 2 years in autism and remain enlarged during early childhood. Moreover, amygdala enlargement in 2-year-old children with autism is disproportionate to overall brain enlargement and remains disproportionate at age 4 years,” the authors write.

According to them, amygdala volume in autistic children was found to be associated with an increase in joint attention ability at age 4, which suggests that alterations to this brain structure may be associated with a core deficit of autism, the authors note.

“The amygdala plays a critical role in early-stage processing of facial expression and in alerting cortical areas to the emotional significance of an event. Amygdala disturbances early in development, therefore, disrupt the appropriate assignment of emotional significance to faces and social interaction,” the authors write.

The researchers are continuing with the follow-up of the research participants so as to determine whether amygdala growth rates continue at the same rate or undergo another period of accelerated growth or a period of decelerated growth in autistic children after age 4.

The study has been published in the Archives of General Psychiatry, one of the JAMA/Archives journals. (ANI)

How the brain handles words

Washington, Apr 30 (ANI): How the brain gives meaning to letters on a page has been a mystery for scientists. Now, a new study has tried to solve the puzzle.

Neuroscientists at Georgetown University Medical Center have found that an area known to be important for reading in the left visual cortex contains neurons that are specialized to process written words as whole word units.

Although some theories of reading as well as neuropsychological and experimental data have argued for the existence of a neural representation for whole written real words (an “orthographic lexicon”), evidence for this has been elusive.

“Reading relies on neural representations that are experience dependent,” says senior author Maximilian Riesenhuber, PhD, of the GUMC Laboratory for Computational Cognitive Neuroscience.

“Evolution did not provide each of us with a little dictionary in our heads,” the expert added.

Because the findings, published in the April 30 issue of Neuron, shed light on how written words are processed in the brain, they also provide clues as to how reading disorders such as dyslexia could arise, Riesenhuber says.

“Previous studies have shown that this brain area is affected in reading disorders such as dyslexia, but it is unclear what the mechanisms involved are. Our data suggest that looking at the neuronal selectivity in this area might provide new insight. For instance, we would expect reading difficulties if neurons never become well tuned to words, making reading a slow, arduous process, just like it would be if reading all nonwords,” the expert added.

The GUMC researchers – Riesenhuber, first author Laurie S. Glezer, MA, and Xiong Jiang, PhD – set up a series of experiments with the participation of volunteers. They showed the participants pairings of words, and used functional Magnetic Resonance Imaging (fMRI) to measure brain blood flow in an area in the left visual cortex called the “visual word form area” while the participants performed a reading task.

Most other studies using fMRI to examine the “visual word form area” have used the averaged neuronal response in which many word stimuli are presented and the change in activity is measured, but this approach does not tease out the response neurons have to individual words, Riesenhuber says. However, by using the technique of fMRI rapid adaptation, in which the stimuli are shown in pairs, it is possible to measure the selectivity of neurons for individual words.

In their experiments, the researchers looked at the response between two visually similar normal words that shared all letters but one (i.e. ‘boat’ and ‘coat’) and found that the neural response to this condition “looked just like when participants saw two words that shared no letters, for example ‘coat’ and ‘fish’,” says Glezer.

“This shows that the neurons in this area of the brain are very selective for individual words. Even though the two words shared all letters but one, there is no overlap in the neural representation, just like when the two words are completely different,” the expert said.

The researchers then looked at the brain’s response to sets of nonwords in which the stimuli look like real words but have never been seen before (i.e. tarm). They found that the response to nonwords was not selective, with similar nonwords appearing to have overlapping neural representations. (ANI)

Cheerful traders ‘encourage risk taking’

London, Apr 8 (ANI): Even an ephemeral exposure to a smiling face can prompt people to make risky investment decisions, concludes a new study.

Graduate student Julie Hall of the University of Michigan in Ann Arbor has shown experiments in which 12 male and 12 female volunteers played a game in which they repeatedly had to choose between investing in a “safe” bond and two much riskier stocks.

For every round of the game, the bond paid out 3 dollars. One of the stocks paid out 5 dollars half of the time, while the other lost 5 dollars at the same rate. At the start of the game, the players were told the rules but didn’t know which of the stocks was good and which was bad: that only emerged as the game unfolded, reports New Scientist.

As with real-world investments, the good stock became bad at certain points during the game, and vice versa, the Cognitive Neuroscience Society meeting in San Francisco heard.

Under these circumstances, the rational strategy is to keep investing in the safe bond. This is mostly what participants did – but only when they were shown an image of a face that showed no emotion before each round. Volunteers who were shown a happy face were much more likely to choose the risky stocks. It made no difference whether the face was displayed long enough for the volunteers to register it consciously, or flashed up fleetingly so it was only perceived subliminally.

Brian Knutson, a psychologist at Stanford University in California, pointed out: “The market is made up of individuals, and individuals have reactions to what’s going on.”

While they were playing the game, the volunteers’ brains were also scanned using functional magnetic resonance imaging. This showed that the risky decisions were preceded by activity in a brain area called the nucleus accumbens, while the safe bets followed excitation in the anterior insular cortex. (ANI)

Suppressing hunger hormone in brain’s ‘pleasure centre’ curbs drug cravings

Washington, Apr 2 (ANI): In a breakthrough towards overcoming addiction, scientists have found that if a hormone related to hunger regulation is blocked in the brain’s “pleasure centre”, it can suppress craving for drugs like cocaine.

The study, led by Shinjae Chung and Olivier Civelli, discovered how the melanin-concentrating hormone works with dopamine in the brain’s “pleasure centre” to create an addictive response to cocaine use.

The researchers have also found that blocking MCH in these brain cells limits cocaine cravings.

Dopamine is a neurotransmitter essential to the normal functioning of the central nervous system. It is also linked with feelings of pleasure and is released in the brain during eating, sex and drug use.

Scientists have discovered increased levels of the neurotransmitter in the nucleus accumbens of drug addicts.

This is the first study to detail the interaction of MCH and dopamine in cocaine addiction and show that it occurs in the nucleus accumbens-a portion of the forebrain believed to play an important role in addiction and feelings of pleasure and fear.

“This discovery indicates that MCH is a key regulator of dopamine in a brain area associated with both pleasure and addiction. We believe that efforts to target MCH may lead to new treatments to break addiction to cocaine and, possibly, other drugs, like amphetamines and nicotine,” said Civelli.

High levels of MCH are known to intensify feelings of hunger and researchers believe that MCH works in the nucleus accumbens to increase the pleasure of eating.

The study showed that dopamine signalling rose when MCH amounts increased in those brain cells.

The researchers also observed that test mice conditioned to develop cocaine cravings had increased amounts of MCH and dopamine in their nucleus accumbens.

However, the cravings disappeared when experimental compounds blocking MCH proteins were administered to the mice.

The researchers also found that mice lacking key receptors for MCH exhibited significantly fewer cocaine cravings.

They next plan to study whether MCH modulation is beneficial in treating other dopamine-related disorders as well.

The study has been published in the online edition of the Proceedings of the National Academy of Sciences. (ANI)

Faith in God ‘reduces anxiety’

London, Mar 18 (ANI): Religious people are less anxious than non-believers when they make mistakes, researchers at the University of Toronto, Scarborough, have found.

In the study, they found that religious people exhibit lower activity than non-believers in a brain region linked to anxiety when erring on a simple test.

“Religion offers an interpretative framework to understand the world. It lets you know when to act, how to act, and what to do in specific situation. It provides a kind of blueprint on how to interact with the world,” New Scientist quoted Michael Inzlicht, a neuroscientist at the University of Toronto, Scarborough, who led the new study, as saying.

He said that religion, and perhaps other strongly held belief systems, buffer against second-guessing decisions.

For the study, Inzlicht’s team tested 50 university students from diverse religious and cultural backgrounds. Christians made up most participants, but his team also tested Muslims, Hindus, Buddhists and atheists.

With a technique that gauges brain activity via dozens of electrodes on the scalp called electroencephalography (EEG), the researchers focused on action in a small brain area called the anterior cingulate cortex (ACC).

“When it’s fired, the response engendered is ‘uh oh, pay attention, something is amiss here’,” he said.

People with anxiety disorders tend to show high activity in this region, and drugs that treat their symptoms calm brain activity in the ACC.

Volunteers took a simple test that other neuroscientists have used to measure ACC activity. On a monitor, subjects see a colour spelled out in letters that either correspond to or contradict the meaning of the word – for example, red spelled out in red letters or blue spelled out in yellow letters, for instance.

Volunteers must press a button to indicate the colour of the letters. The students with strong religious beliefs, as measured by their agreement with statements such as “My religion is better than others” or “I would support a war if my religion supported it”, exhibited less ACC activation than students with less fervent beliefs.

Tests with another group of students, who were asked how strongly they believed or disbelieved in God, came to a similar conclusion.

Even after accounting for self-esteem, intelligence and other personality traits, the researchers found that religious devotion predicted volunteers’ ACC activity.

One explanation is that people with a genetic predisposition to reduced ACC activity gravitate toward religion.

“It’s possible that if you’re born with a certain kind of brain, you’re predisposed to religion,” Inzlicht said.

However, he suspects that religious belief is driving the association.

The study is published in the journal of Psychological Science. (ANI)

Boffins identify tiny brain area key to fear of rivals and predators

Washington, Mar 10 (ANI): Researchers from University of Southern California have identified an area of hypothalamus in the brain, which is key to animals’ fear of territorial rivals and predators.

The team of neurologists led by Larry Swanson found that mice lose their fear of territorial rivals when a tiny piece of their brain is neutralized.

Brain’s amygdala region has long been studied by researchers as the region of fear. However, the new study has shown that primal fear responses do not depend on the amygdala, but on an obscure corner of the primeval brain.

During the study, the researchers examined the brain activity of rats and mice exposed to cats, or to rival rodents defending their territory.

They found that both experiences activated neurons in the dorsal premammillary nucleus, part of an ancient brain region called the hypothalamus.

For further analysis, the research team then made tiny lesions in the same area. Those rodents behaved far differently.

“These animals are not afraid of a predator,” Swanson said.

“It’s almost like they go up and shake hands with a predator.

“It’s amazing that these lesions appear to abolish innate fear responses.

“The same basic circuitry is found in primates and people that we find in rats and mice,” he added.

The study appears in Proceedings of the National Academy of Sciences. (ANI)

Common blood pressure drug may banish fears, post traumatic stress

London, February 16 (ANI): A commonly prescribed drug for blood pressure can eliminate phobias and post traumatic stress for good, say researchers.

Merel Kindt and her colleagues at the University of Amsterdam, the Netherlands, have revealed that this drug is called the beta blocker propranolol.

The researcher points out that people who experienced traumatic events-like rape and car crashes-showed fewer signs of stress while recalling the event when they had been injected with the beta blocker propranolol in experiments conducted in the past.

However, it still remained unclear whether the effect would be permanent or not because fearful memories often return, even after people have been treated for them.

Merel said that her team investigated whether propranolol could stop fear returning in the longer term by conditioning 60 healthy students to associate a picture of a spider with an electric shock, so that they would eventually be startled by the picture even in the absence of a shock.

The researchers noted that the startle response was eliminated in students who were given oral propranolol before seeing the picture.

They even observed that the response did not return when the students were put through a second round of conditioning, which should have reinstated their fear.

Merel said that that observation indicated that the link between the students’ memories and fears might have been permanently broken.

She further said that those given a placebo pill could eventually be trained not to be startled by the spider picture, by repeatedly showing it to them in the absence of a shock.

Experiencing traumatic events causes the body to release adrenaline, which affects ahe brain area involved in emotional processing called the amygdala, and makes an emotional connection to the memory.

Merel points out that reliving the memory triggers further release of adrenaline, reinforcing the memory still further.

Given that propranolol blocks adrenaline receptors in the amygdala, she thinks that it may also block this reinforcement process and break fear association.

“We can’t prove that the memory has gone away, but it is at least weakened so much that we can’t find it anymore,” New Scientist magazine quoted her as saying.

University College London memory expert Chris Brewin calls the findings interesting, but warns that Merel’s team only tested the volunteers over the course of three days.

“The fear might come back if they tested them several weeks later,” he says.

He also pointed out that he research team only looked at the degree to which the volunteers were startled, but conditions like post traumatic stress disorder often involve other emotions such as anger and shame, and it had yet to be found how propranolol would affect them.

A research article on the study has been published in the journal Nature Neuroscience. (ANI)