Mathematical model to help in installation of tsunami detection buoys

Washington, April 29 (ANI): Australian scientists have come up with a mathematical model that promises to pin point ten optimal sites for the installation of tsunami detection buoys and sea-level monitors.

The quick and cost-effective installation of a detection system could provide warning for the maximum number of people should a potentially devastating tsunami occur again in the Indian Ocean.

The author of the study, Layna Groen and Lindsay Botten of the Department of Mathematical Sciences, at the University of Technology, and Katerina Blazek previously at Sinclair Knight Merz, in Sydney, NSW, Australia, suggest that their model has significant implications for the construction and maintenance of the tsunami warning system in the Indian Ocean.

The Intergovernmental Oceanographic Commission (IOC) of the United Nations Educational, Scientific and Cultural Organisation (UNESCO) planned the establishment of the Indian Ocean Tsunami Warning and Mitigation System (IOTWS).

The detection/alert system is the crucial component consisting of seismic detectors, sea-level monitors and deep-sea pressure sensors attached to deep ocean buoys.

Groen and colleagues have focused on the latter two components as being critical to an adequate warning system.

They point out that relatively few detection buoys are yet in place and a number of sea-level monitoring stations are still to be constructed.

Their study, which uses the well-known modelling tool “Mathematica”, should help the IOTWS decision makers in determining where the remaining buoys should be placed.

The team”s analysis supports the positioning of the 40 proposed buoys, but points out that just 1o buoys would be adequate for warning the maximum number of people.

They add that the same mathematical modelling approach could be applied to tsunami detection in the Atlantic Ocean, the Mediterranean, Caribbean, and Black Seas.

The study has appeared in the International Journal of Operational Research. (ANI)

Losing just 6kgs ”enough for big health gain”

Sydney, April 20 (ANI): Losing just six kilograms results in a major health gain, says a new study.

Australian scientists said that obesity raises the risk of type 2 diabetes, heart disease and some cancers.

It sparks damaging changes to immune systems, they added.

However, the new study showed that losing just six kilograms was enough to dramatically turn things around.

“We”ve found that a modest weight loss, of about six kilograms, is enough to bring the pro-inflammatory nature of circulating immune cells back to that found in lean people,” the Sydney Morning Herald quoted study”s co-author Katherine Samaras as saying in a statement.

“These inflammatory cells are involved in promoting coronary artery disease and other illnesses associated with obesity.

“This is the first time it has been shown that modest weight reduction reverses some of the very adverse inflammatory changes we see in people with diabetes,” she added.

To reach the conclusion, Samaras and her colleague studied the immune system functioning of obese people with type 2 diabetes or prediabetes who were put on a restricted calorie diet.

Study participants were limited to between 1000 to 1600 calories a day for 24 weeks, while they also had gastric banding surgery halfway through the trial to further restrict their food intake.

The research showed that only a small amount of weight loss could reap an 80 per cent reduction in these pro-inflammatory cells as well as other positive effects for the immune system.

Samaras said overall the study showed how even minor lifestyle changes could avert the development of life-threatening illness.

The study has been published in the Journal of Clinical Endocrinology Metabolism this week. (ANI)

Scientists unearth Australian T rex

Australian scientists say they have discovered the first evidence that an ancestor of the mighty Tyrannosaurus rex once roamed across Australia.

The finding, published today in the journal Science, fills a major gap in the evolutionary history of T rex and overturns the theory the giant predator was a purely northern hemisphere animal.

It also puts a dampener on hopes of finding a unique Australian dinosaur, says Museum Victoria curator of vertebrate palaeontology Dr Tom Rich.

The discovery is based on a pubic bone found about 20 years ago at Dinosaur Cove, 220 kilometres west of Melbourne in Victoria.

It was made after Dr Rich took a number of isolated and unidentified bones overseas for identification.

Conspicuous feature

Lead author Dr Roger Benson, a research fellow in the Department of Earth Sciences at the University of Cambridge, says he instantly recognised one of the bones belonged to a coelurosaur.

Coelurosaurs are the group of mainly small-bodied, predatory dinosaurs that includes birds at one end and tyrannosaurs at the other, Dr Benson says.

He says the identification was initially based on “one conspicuous feature”.

Dr Benson says the far end of the pubic bone was expanded into a “boot” shape fore and aft, but was very narrow across.

“Basically, our [the Museum Victoria] pubis is almost identical to that of T rex, only much smaller,” Dr Benson said.

The new species, which Dr Rich says would have been about one-third to one-quarter the size of T rex, shares other features with the giant predator, including short arms and powerful jaws.

“It’s much more similar to T rex than one other tyrannosaur (Raptorex, from China) of slightly older age than ours,” Dr Benson said.

“We know Raptorex had a robust skull and small arms and we know that our new fossil is from a tyrannosaur even more closely related to T rex. Thus it’s most likely the general body plan of our new one was similar.”

Surge in discovery

Until recently the only known tyrannosaurs were those like T rex – giant predators from Asia and North America that lived about 70 million years ago, just before the Cretaceous mass extinction, says Dr Benson.

However in the past decade a “surge” in discoveries has revealed diverse types and body sizes in the tyrannosauroid family from up to 170 million years back in the Middle to Late Jurassic.

“It’s these discoveries, mostly man-sized or smaller, that have filled in the story of tyrannosaur evolution,” says Dr Benson.

“Since all discoveries have been from the northern hemisphere, tyrannosaurs have been considered as northern dinosaurs that might have just never made it down into the south.

“The new discovery shows that this is wrong and that 110 million years ago tyrannosaurs were probably global. This poses a question. Why did tyrannosaurs grow to giant size and dominance in the north, but apparently not in the south?”

Dr Rich says the new species of Tyrannosaurus also shows the likelihood of finding a unique Australian dinosaur is low.

“The picture that seems to be emerging is that dinosaurs were more or less cosmopolitan,” he says.

“We are getting elements that look like those found in the northern hemisphere and we haven’t found the dinosaur equivalent of the koala; we don’t seem to have a unique dinosaur.”

Hypersonic plane passes latest test

The Federal Government says Australian and US defence scientists have successfully tested a hypersonic aircraft for the second time in South Australia’s outback.

The aircraft soared through the atmosphere at more than 5,000 kilometres per hour after taking off from the Woomera Test Range.

The experiment was first conducted in May last year and more tests are planned.

Hypersonic flight could potentially allow people to travel between Sydney and London in just two hours.

Sound recordings can help detect obstructive sleep apnoea

Melbourne, Sept 11 (ANI): Australian scientists have come up with a non-invasive screening tool for detecting obstructive sleep apnoea (OSA).

Snoring is a very early symptom of sleep apnoea, however, monitoring the changes in pitch, frequency and other characteristics of the snores can help detect OSA.

Biomedical engineer and co-researcher Dr Udantha Abeyratne, of the University of Queensland have developed a non-contact method of screening patients suspected of OSA, which could eventually be used at home.

Abeyratne says the device records the sounds of a person’s snoring, which “is a very early symptom of sleep apnea.”

Currently, the only way to diagnose a person with OSA is to have them spend a night at a sleep centre or hospital, hooked up to a machine that monitors their sleep continuously.

“There are very long waiting lists to come into the hospital and get tested,” ABC Online quoted Abeyratne as saying.

He said compared to the traditional method of diagnosing OSA, the sound recordings method is 90pct accurate.

Abeyratne hopes the technology will be available for use in people’s homes in the next three to five years. (ANI)

Scientists imitate viruses to deliver therapeutic genes

Washington, September 1 (ANI): Australian scientists have developed a new gene therapy vector that uses the same machinery as viruses to transport their cargo into cells.

David Jans, from the Nuclear Signaling Laboratory at Monash University in Victoria, says that this achievement has raised the hope that one day therapeutic DNA will begin to be transferred to a cell’s nucleus far more efficiently than in the past, and thus there will be more effective treatments for several genetic disorders and some types of cancers.

“Through the use of proteins that mimic key functions of viruses for the packaging and transport of therapeutic DNA, we hope to improve the efficiency, and above all, the specificity of human gene therapy,” he said.

“Following the creation of efficient, specific and safe DNA delivery vectors, the challenges in human gene therapy will be able to move on from questions of delivery to actual clinical application,” he added.

A gene therapy vector is used to deliver a therapeutic gene or a portion of DNA into a cell nucleus similar to how a syringe is used to inject medicines.

To create the new gene therapy vector, Jans and his colleagues used pieces of different genes to create a protein called a “modular DNA carrier”, which can be produced by bacteria.

Writing about their work in The FASEB Journal, the researchers have revealed that this protein carries and delivers therapeutic DNA to a cell’s nucleus, where it reprograms a cell to function properly.

While experimenting in their laboratory, the research team combined these carrier proteins with therapeutic DNA, and attached them to cell membrane receptors and the nuclear import machinery of target cells.

In turn, according to the researchers, the packaged DNA moved into the cell through the cytoplasm and into the nucleus.

“Effective gene therapy is clearly the best way to treat heritable diseases. It’s also an approach to other diseases where the environment or infection messes up our genes.” said Dr. Gerald Weissmann, the Editor-in-Chief of The FASEB Journal.

“The Australians have worked out how viruses identify our nuclear ZIP-code, and have delivered therapeutic genes to the same address. This work opens up a new era of pharmaceutical development,” Dr. Weissmann added. (ANI)

Human-generated aerosols from northern hemisphere may affect rainfall patterns in Australia

Washington, August 27 (ANI): Australian scientists, using a climate model, have suggested that human-generated aerosols from the northern hemisphere may have contributed to increased rainfall in north-western and central Australia, and decreased rainfall in parts of southern Australia.

According to lead researcher, Dr Leon Rotstayn, Principal Research Scientist at the Centre for Australian Weather and Climate Research, a partnership between CSIRO and the Bureau of Meteorology, “Perhaps surprisingly, inclusion of northern hemisphere aerosols may be important for accurate modelling of Australian climate change.”Aerosols come from many different sources.

Sulphur is released when we burn coal and oil. More dust, also an aerosol, circulates in the atmosphere when land is cleared, burned or overgrazed.

Some aerosols occur naturally like sea spray and volcanic emissions, but NASA estimates ten percent of the total aerosols in the atmosphere are caused by people.

Most of this ten percent is in the northern hemisphere.
European researchers, attending the international ‘Water in a changing climate’ science conference in Melbourne from August 24-28, will discuss a new forecasting service that will identify in unprecedented detail where these aerosols are coming from and where they are going.

The new service, part of Europe’s Global Monitoring for Environment and Security (GMES) initiative, will give global information on how pollutants move around the world across oceans and continents, and will refine estimates of their sources and sinks.

According to Dr Adrian Simmons from the European Centre for Medium-Range Weather Forecasts, which is coordinating the multi-institution initiative, “The service will give much more detailed forecast information on air quality over Europe and provide the basis for better health advice across Europe and beyond”.

The service has clear implications for environmental policy and legislation. (ANI)

Artificial red blood cells a step closer

Melbourne, Aug 24 (ANI): A team of Australian scientists has genetically modified human embryonic stem cells to glow red when they develop into premature red blood cells.

The breakthrough is seen as the next step in producing artificial blood.

Dr Andrew Elefanty at Monash University in Melbourne and his colleagues inserted specific genes that code for colour, into the DNA of a manufactured stem cell line.

Stem cells are the template from which all cell types in the body form.

He says the coloured genes, known as ‘reporters’, highlight the emergence of certain cell types.

“What we’ve said to the stem cells is when you’re going to turn on the gene for globin we want you to also turn on a red light,” ABC Science quoted Elefanty as saying.

He says fluorescing cells are a useful tool to help work out the best way to engineer specific cells.

“We learn what the right growth enhancing substances are that the body normally uses and we put those into the laboratory,” he said.

Elefanty says fluorescing cells also allows scientists to monitor the cells when they’ve been injected into animals.

“Sometimes it’s not that easy to tell the difference between the ones you put in and the ones that were already there,” he said.

The researchers are hoping the development of glowing stem cell lines will help them work out how to develop mature red blood cells faster.

However, Elefanty says they are still a way off producing artificial blood that could be used in human blood transfusions.

He and his colleagues are working with Queensland researchers to develop ways to mature the cells, but there are still many issues to resolve.

“We’ve got to make sure the cells are safe, that they don’t keep growing and form tumours and that the immune system doesn’t reject them,” he said.

The research has been published in today’s edition of Nature Methods. (ANI)

Boeing set to test unmanned aircraft in Australia

Brisbane, July 12 (ANI): Australian scientists and US aviation giant Boeing are set to test unmanned aircrafts, which would share airspace with piloted passenger planes without causing any collision.

In a non-descript shed in suburban South Park in Seattle, a team of young Boeing engineers are overseeing an experiment that provides a startling glimpse into the future.

Their 30-metre by 15 metre by five-metre-high unmanned aerial vehicle (UAV) “swarming” laboratory looks like a small indoor cricket shed with model rotor aircraft parked on the concrete floor.

Suddenly the UAVs are airborne and swarming around the shed, their pre-determined tracks, altitudes and collision avoidance mechanisms already programmed in using advanced algorithms that could ultimately spell the end of piloted aircraft, The Courier-Mail reports.

The aim of this cutting edge science is to build the mathematical models that will allow uninhabited aircraft to fly safely in controlled airspace.

Boeing’s new Australian research chief Bill Lyons talks about the aim behind the experiment: “To allow (unmanned) systems to operate at least as well as human piloted systems.”

The algorithms developed in the swarm lab will soon be put to the test in the skies above Kingaroy in southern Queensland in the world’s first ever trial of unmanned aircraft inside controlled airspace.

Airspace authorities in both the US and Australia, highly wary of having pilotless drones in potential conflict with airliners carrying hundreds of passengers, will require 100 per cent guarantees before they will allow the two to mix.

Senior Boeing engineer John Vian said the major challenge for unmanned aircraft operating in controlled air space is safety.

“We don’t know how these systems will develop. For these systems to be viable they have to be reliable and totally autonomous. We develop the technology, how it is applied is up the customer,” Dr. Vian said. (ANI)

Teleportation may soon be a reality!

Sydney, June 22 (ANI): Australian scientists have developed a new method for transmitting data with light that may lead to the development of teleportation technology and super-fast quantum computers.

According to a report in www.news.com.au, the research team, from the Australian National University, developed a new approach to generating quantum entanglement in beams of light using only two parts.

Quantum entanglement is a process in which two objects are linked together in such a way that any changes to the properties of one can be measured from the other regardless of the distance between them.

This process of linking particles has existed for a few years, but according to team leader Dr Jiri Janousek, this new method allows it to be achieved in a much simpler way.

“Usually, when you want to generate entanglement you need a lot of sources of light and a lot of receivers but we found a way to use only one source and one receiver to generate and measure entanglement,” Dr Janousek said.

Dr Janousek and his team’s new method involves entangling two specially modified beams of light so that changes to the amplitude or phase of one beam can be measured with the other.

Dr Janousek said that by only using two parts, it allows the technology to be more easily scaled up opening a number of potential uses in technologies ranging from computing, communications and even teleportation.

“This finding is one more piece in the puzzle towards the future realisation of quantum computers, which would be many times faster and more powerful than existing computers,” he said.

“For teleportation, you again need a source of entangled beams; so in effect, it could be used for teleportation as well,” he added.

But, Dr Janousek said that it will be a while before this technology works its way into any consumer devices.

“We always talk about 50 years as where we could get real machines that could use the technologies which we have developed so far,” he said. (ANI)

Stem cell lenses can help the blind see again

Melbourne, May 28 (ANI): In a world-first breakthrough, Australian scientists have used contact lenses coated in stem cells to restore a person’s sight.

Medical researchers from University of New South Wales used the technique to treat the damaged corneas of three patients. The patients’ vision improved within weeks of the groundbreaking procedure.

The results are published in the journal Transplant.

In the procedure, stem cells were harvested from the eyes of each patient. Then, they were cultured inside a contact lens, which was then stuck onto a damaged cornea in a “transplant” of regenerative cells.

The three patients treated had very poor vision caused by corneal disease – the fourth most common form of blindness, affecting around 10million worldwide.

“The procedure is totally simple and cheap,” News.com.au quoted university’s Dr Nick Di Girolamo, as saying.

“Unlike other techniques … there’s no suturing, there is no major operation, all that’s involved is harvesting a minute amount – less than a millimetre – of tissue from the ocular surface,” the expert added.

The lens stayed on for 10 days allowing stem cells to change their form, colonise and repair the cornea.

Girolamo said that in the two cases the stem cells were taken from their healthy eye – but the third patient posed an additional challenge because of a congenital disorder which affected both eyes.

“We took them from another part of the eye altogether – the conjunctiva which also harbours stem cells,” Di Girolamo said.

“The stem cells were able to change from the conjunctival phenotype to a corneal phenotype after we put them onto the cornea … that’s the beauty of stem cells,” the expert added. (ANI)

Soon, genetic test to identify pregnancy risks

Washington, May 12 (ANI): A team of Australian scientists is developing a genetic test to identify pregnancies at risk of complications before symptoms arise.

The research team, led by Associate Professor Claire Roberts, Senior Research Fellow in the University of Adelaide’s new Robinson Institute, has identified subtle variations in specific genes within the mother, father or baby that indicate the mother is more likely to suffer from pregnancy complications.

This advance will permit tailored, and sometimes potentially life-saving, antenatal care and constitutes a quantum leap forward in the care of pregnant women and their babies.

The research has also identified potential therapies for use in early pregnancy to improve placental development and function and reduce the risk from pregnancy complications.

“Our findings show that it does actually take two for successful pregnancy. Pregnancy success is determined by a complex interaction of maternal, paternal and environmental characteristics that together dictate how well the placenta develops and functions and how the mother adapts to pregnancy,” Roberts said.

“Defects in how well the placenta develops and functions are implicated in common pregnancy complications ranging from miscarriage, through preeclampsia, pre-term birth and fetal growth restriction. The problem with complications is that we are unable to predict which women are at risk until symptoms develop, and then therapies can be too little, too late,” Roberts added. (ANI)

Soon, mobile phones to monitor cardiac patients

Melbourne, May 2 (ANI): In a bid to encourage heart patients to complete their rehabilitation programs after surgery, Australian scientists have come up with a new technique that will see nurses monitoring them via a mobile phone.

The trial, being run by the CSIRO’s Australian E-Health Research Centre (AEHRC) and Queensland Health, uses a mobile phone to collect and send health-related information about patients’ activities at home to a central computer.

AEHRC chief executive officer Dr Phil Gurney said that less than 20 pct of the heart surgery patients complete their six-week rehabilitation program, following the need for patients to return regularly to the hospital for the rehab program.

“We are largely using technology that is available, but we have customised it to our purposes,” ABC Science quoted Gurney as saying.

The mobile phones have an inbuilt accelerator that measures physical activity such as the number of steps walked.

The patients also use the phone to record data from blood pressure monitors and scales.

The participants were asked to take photos of meals they eat or videos of themselves exercising, and use an electronic diary on the phone to record observations about their stress levels, diet, smoking and alcohol intake.

The information is sent to a central computer.

“We tried to take advantage of what technology is available because we want to get it out to as many people as possible and be cost effective,” he added.

Gurney said that a small subset of the group is also trailing home use of a heart-rate monitor while exercising. The data is transferred to the phone automatically via Bluetooth.

He said that if the trials are successful, the technique could be used by patients who live in remote areas or have commitments that make hospital visits difficult. (ANI)

Oceans were filled with oxygen 700 million years earlier than believed

Sydney, March 17 (ANI): An international team of geologists has claimed that photosynthesizing life forms created an excess of oxygen in the oceans 700 million years earlier than previous estimates suggest.

According to a report in ABC News, bands of haematite in the Marble Bar Cherst reveal the presence of aerobic bacteria nearly 3.5 billion years ago.

The research pushes back the earliest appearance of photosynthesizing organisms from 2.7 to 3.46 billion years ago.

Microscopic organisms such as cyanobacteria create oxygen as a by-product of photosynthesis.

The timing of their first appearance is hotly debated as it provides clues as to how early life on earth evolved.

Until now, the earliest evidence of photosynthesis was microscopic fossils found in shale rocks in Western Australia dating from 2.7 billion years ago.

Now, a team of Japanese, US and Australian scientists, led by Dr Masamichi Hoashi of the Kagoshima University, Japan, have found evidence for oxygen in ancient sea water from marine sedimentary rocks in the Pilbara region of Western Australia.

The evidence comes from tiny crystals of the iron-oxide mineral haematite in a 160-metre-long core section that forms part of the Marble Bar Chert.

Haematite can form in the presence of aerobic (oxygen-loving) bacteria in the water, or by photo-electric processes in the upper 10 metres of seawater.

According to the researchers, haematite crystals in the Marble Bar Chert formed in water at least 200 meters deep, because microscopic analysis of the rocks show no sign of wave action or other structures characteristic of shallow-water sediments.

The orientation and nature of the grains of haematite also show that it precipitated directly from the seawater, rather than forming later from other processes, such as the movement of groundwater, they added.

“These data strongly suggest that oxygenic photoautotrophs flourished in the photic zone of the 3.46 billion-year-old oceans and supplied molecular oxygen to the deep water,” said the researchers.

Professor Hiroshi Ohmoto from the NASA Astrobiology Institute and Department of Geosciences at the Pennsylvania State University said that other data backs their claim for an early development of photosynthesizing life.

“Recently accumulated massive amounts of geochemical and biochemical data can be better explained by a theory postulating the emergence of oxygenic photosynthesis and the development of a fully oxygenated atmosphere in the very early evolutionary stage,” said Ohmoto.

“Once cyanobacteria appeared in one area of the ocean, it probably took less than 10 million years to fully oxygenate the atmosphere and oceans,” he added. (ANI)